Published in Nat Neurosci on July 01, 2001
Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza. Sci Transl Med (2010) 3.02
Signaling mechanisms underlying Slit2-induced collapse of Xenopus retinal growth cones. Neuron (2006) 2.45
Robo4 cooperates with CXCR4 to specify hematopoietic stem cell localization to bone marrow niches. Cell Stem Cell (2011) 1.98
Dystroglycan organizes axon guidance cue localization and axonal pathfinding. Neuron (2012) 1.76
Binding site for Robo receptors revealed by dissection of the leucine-rich repeat region of Slit. EMBO J (2004) 1.59
MicroRNA-218 regulates vascular patterning by modulation of Slit-Robo signaling. Circ Res (2010) 1.56
Cell migration in the normal and pathological postnatal mammalian brain. Prog Neurobiol (2009) 1.56
A molecular mechanism for the heparan sulfate dependence of slit-robo signaling. J Biol Chem (2006) 1.37
The chemical neurobiology of carbohydrates. Chem Rev (2008) 1.33
Modulation of syndecan-1 shedding after hemorrhagic shock and resuscitation. PLoS One (2011) 1.32
Regulation of axonal outgrowth and pathfinding by integrin-ECM interactions. Dev Neurobiol (2011) 1.27
Dual function of Slit2 in repulsion and enhanced migration of trunk, but not vagal, neural crest cells. J Cell Biol (2003) 1.24
Wnt modulators in the biotech pipeline. Dev Dyn (2010) 1.23
Assembly of lamina-specific neuronal connections by slit bound to type IV collagen. Cell (2011) 1.22
Sugar codes for axons? Neuron (2005) 1.22
Extracellular matrix: functions in the nervous system. Cold Spring Harb Perspect Biol (2011) 1.21
Structural and functional analysis of slit and heparin binding to immunoglobulin-like domains 1 and 2 of Drosophila Robo. J Biol Chem (2008) 1.19
Vascular Robo4 restricts proangiogenic VEGF signaling in breast. Proc Natl Acad Sci U S A (2010) 1.15
Endogenous endothelial cell signaling systems maintain vascular stability. Angiogenesis (2009) 1.12
Extracellular sugar modifications provide instructive and cell-specific information for axon-guidance choices. Curr Biol (2008) 1.12
A roundabout way to cancer. Adv Cancer Res (2012) 1.11
Permissive corridor and diffusible gradients direct medial ganglionic eminence cell migration to the neocortex. Proc Natl Acad Sci U S A (2003) 1.08
Modulation of inflammation by slit protein in vivo in experimental crescentic glomerulonephritis. Am J Pathol (2004) 1.07
Slit/Robo signaling modulates the proliferation of central nervous system progenitors. Neuron (2012) 1.01
Extracellular matrix and its receptors in Drosophila neural development. Dev Neurobiol (2011) 0.98
Robo4-dependent Slit signaling stabilizes the vasculature during pathologic angiogenesis and cytokine storm. Curr Opin Hematol (2011) 0.97
Heparan sulfate regulates intraretinal axon pathfinding by retinal ganglion cells. Invest Ophthalmol Vis Sci (2011) 0.96
Proteoglycans and neuronal migration in the cerebral cortex during development and disease. Front Neurosci (2015) 0.95
A role for S1P signalling in axon guidance in the Xenopus visual system. Development (2007) 0.94
Netrin-1 attracts axons through FAK-dependent mechanotransduction. J Neurosci (2012) 0.94
MicroRNA control of vascular endothelial growth factor signaling output during vascular development. Arterioscler Thromb Vasc Biol (2013) 0.90
High structural resolution hydroxyl radical protein footprinting reveals an extended Robo1-heparin binding interface. J Biol Chem (2015) 0.89
Structure and functional relevance of the Slit2 homodimerization domain. EMBO Rep (2009) 0.88
Characterization of the interaction between Robo1 and heparin and other glycosaminoglycans. Biochimie (2013) 0.87
The extracellular matrix proteoglycan perlecan facilitates transmembrane semaphorin-mediated repulsive guidance. Genes Dev (2012) 0.87
Heparan sulfate proteoglycan specificity during axon pathway formation in the Drosophila embryo. Dev Neurobiol (2011) 0.86
Glycosaminoglycans of the porcine central nervous system. Biochemistry (2010) 0.84
Mechanochemical regulation of growth cone motility. Front Cell Neurosci (2015) 0.80
The C-terminal fragment of axon guidance molecule Slit3 binds heparin and neutralizes heparin's anticoagulant activity. Glycobiology (2012) 0.79
Inhibitors of slit protein interactions with the heparan sulphate proteoglycan glypican-1: potential agents for the treatment of spinal cord injury. Clin Exp Pharmacol Physiol (2009) 0.78
Sugar glues for broken neurons. Biomol Concepts (2013) 0.78
Cationic Peptides and Peptidomimetics Bind Glycosaminoglycans as Potential Sema3A Pathway Inhibitors. Biophys J (2016) 0.76
The role of heparan sulphate in development: the ectodermal story. Int J Exp Pathol (2016) 0.75
Integrated Approach to Identify Heparan Sulfate Ligand Requirements of Robo1. J Am Chem Soc (2016) 0.75
Panels of chemically-modified heparin polysaccharides and natural heparan sulfate saccharides both exhibit differences in binding to Slit and Robo, as well as variation between protein binding and cellular activity. Mol Biosyst (2016) 0.75
Analyzing the role of heparan sulfate proteoglycans in axon guidance in vivo in zebrafish. Methods Mol Biol (2015) 0.75
The role of heparan sulfate deficiency in autistic phenotype: potential involvement of Slit/Robo/srGAPs-mediated dendritic spine formation. Neural Dev (2016) 0.75
The Amyloid Precursor Protein Is a Conserved Receptor for Slit to Mediate Axon Guidance. eNeuro (2017) 0.75