Published in Trends Pharmacol Sci on July 01, 2001
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An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4. J Exp Med (2003) 2.91
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The Arabidopsis cupin domain protein AtPirin1 interacts with the G protein alpha-subunit GPA1 and regulates seed germination and early seedling development. Plant Cell (2003) 1.51
Persistent signaling by dysregulated thrombin receptor trafficking promotes breast carcinoma cell invasion. Mol Cell Biol (2004) 1.50
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Dynamic regulation of a GPCR-tetraspanin-G protein complex on intact cells: central role of CD81 in facilitating GPR56-Galpha q/11 association. Mol Biol Cell (2004) 1.36
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Gamma-linolenic and stearidonic acids are required for basal immunity in Caenorhabditis elegans through their effects on p38 MAP kinase activity. PLoS Genet (2008) 1.09
The G-protein-coupled receptor GCR1 regulates DNA synthesis through activation of phosphatidylinositol-specific phospholipase C. Plant Physiol (2003) 1.08
A human homeotic transformation resulting from mutations in PLCB4 and GNAI3 causes auriculocondylar syndrome. Am J Hum Genet (2012) 1.07
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Signaling from the human melanocortin 1 receptor to ERK1 and ERK2 mitogen-activated protein kinases involves transactivation of cKIT. Mol Endocrinol (2010) 1.06
The G protein-coupled receptor 87 is necessary for p53-dependent cell survival in response to genotoxic stress. Cancer Res (2009) 1.05
Role of G12 proteins in oncogenesis and metastasis. Br J Pharmacol (2009) 1.05
Role of the amino terminus of G protein-coupled receptor kinase 2 in receptor phosphorylation. Biochemistry (2009) 1.05
The angiotensin II type I receptor-associated protein, ATRAP, is a transmembrane protein and a modulator of angiotensin II signaling. Mol Biol Cell (2003) 1.04
The Src kinase Lyn is required for CCR5 signaling in response to MIP-1beta and R5 HIV-1 gp120 in human macrophages. Blood (2006) 1.03
Human herpesvirus 8-encoded vGPCR activates nuclear factor of activated T cells and collaborates with human immunodeficiency virus type 1 Tat. J Virol (2003) 1.02
The C terminus of mouse monocyte chemoattractant protein 1 (MCP1) mediates MCP1 dimerization while blocking its chemotactic potency. J Biol Chem (2010) 1.02
A new aspect of the TrkB signaling pathway in neural plasticity. Curr Neuropharmacol (2009) 1.01
Driving cellular plasticity and survival through the signal transduction pathways of metabotropic glutamate receptors. Curr Neurovasc Res (2005) 1.01
G protein-coupled receptors participate in cytokinesis. Cytoskeleton (Hoboken) (2012) 1.01
Molecular basis of a novel oncogenic mutation in GNAO1. Oncogene (2011) 1.00
Cellular and chemical neuroscience of mammalian sleep. Sleep Med (2010) 0.99
Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin. Mol Biol Cell (2014) 0.98
RANTES stimulates Ca2+ mobilization and inositol trisphosphate (IP3) formation in cells transfected with G protein-coupled receptor 75. Br J Pharmacol (2006) 0.98
G-protein-coupled receptors and melanoma. Pigment Cell Melanoma Res (2008) 0.97
The evolving impact of g protein-coupled receptor kinases in cardiac health and disease. Physiol Rev (2015) 0.97
Functional modulation of human monocytes derived DCs by anaphylatoxins C3a and C5a. Immunobiology (2011) 0.97
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Luteinizing hormone receptor mRNA down-regulation is mediated through ERK-dependent induction of RNA binding protein. Mol Endocrinol (2010) 0.96
Synthesis, trafficking, and localization of muscarinic acetylcholine receptors. Pharmacol Ther (2008) 0.96
Sexual experience in female rodents: cellular mechanisms and functional consequences. Brain Res (2006) 0.96
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Ceramide kinase regulates phospholipase C and phosphatidylinositol 4, 5, bisphosphate in phototransduction. Proc Natl Acad Sci U S A (2009) 0.95
Adrenomedullin Function in Vascular Endothelial Cells: Insights from Genetic Mouse Models. Curr Hypertens Rev (2011) 0.95
Regulation of G-protein-coupled signaling pathways in allergic inflammation. Immunol Res (2009) 0.94
A regulator of G protein signaling-containing kinase is important for chemotaxis and multicellular development in dictyostelium. Mol Biol Cell (2003) 0.93
Novel osmotin attenuates glutamate-induced synaptic dysfunction and neurodegeneration via the JNK/PI3K/Akt pathway in postnatal rat brain. Cell Death Dis (2014) 0.93
CysLT1 receptor-induced human airway smooth muscle cells proliferation requires ROS generation, EGF receptor transactivation and ERK1/2 phosphorylation. Respir Res (2006) 0.92
Beta-arrestin scaffolding of phosphatidylinositol 4-phosphate 5-kinase Ialpha promotes agonist-stimulated sequestration of the beta2-adrenergic receptor. J Biol Chem (2008) 0.92
Phospholipase Cγ1 connects the cell membrane pathway to the nuclear receptor pathway in insect steroid hormone signaling. J Biol Chem (2014) 0.92
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Epigenetic repression of regulator of G-protein signaling 2 promotes androgen-independent prostate cancer cell growth. Int J Cancer (2011) 0.91
Genome wide survey of G protein-coupled receptors in Tetraodon nigroviridis. BMC Evol Biol (2005) 0.90
G protein-coupled receptors as therapeutic targets for multiple sclerosis. Cell Res (2012) 0.90
Adrenergic and serotonin receptors affect retinal superoxide generation in diabetic mice: relationship to capillary degeneration and permeability. FASEB J (2015) 0.90
Signalling of the M3-muscarinic receptor to the anti-apoptotic pathway. Biochem J (2004) 0.90
Rapgef2 connects GPCR-mediated cAMP signals to ERK activation in neuronal and endocrine cells. Sci Signal (2013) 0.90
Disruption of aminergic signalling reveals novel compounds with distinct inhibitory effects on mosquito reproduction, locomotor function and survival. Sci Rep (2014) 0.89
Structural permeability of complex networks to control signals. Nat Commun (2015) 0.89
Regulation of neurite outgrowth by G(i/o) signaling pathways. Front Biosci (2008) 0.89
Molecular basis of lysophosphatidic acid-induced NF-κB activation. Cell Signal (2010) 0.89
RGS16 attenuates pulmonary Th2/Th17 inflammatory responses. J Immunol (2012) 0.89
The clinical and functional relevance of microparticles induced by activated protein C treatment in sepsis. Crit Care (2011) 0.89
Denatonium induces secretion of glucagon-like peptide-1 through activation of bitter taste receptor pathways. Diabetologia (2014) 0.89
Endogenous mono-ADP-ribosylation of the free Gbetagamma prevents stimulation of phosphoinositide 3-kinase-gamma and phospholipase C-beta2 and is activated by G-protein-coupled receptors. Biochem J (2002) 0.87
Pulmonary fibroblasts, an emerging target for anti-obstructive drugs. Naunyn Schmiedebergs Arch Pharmacol (2008) 0.87
Genomic profiling of mixer and Sox17beta targets during Xenopus endoderm development. Dev Dyn (2006) 0.87
Functional significance of GnRH and kisspeptin, and their cognate receptors in teleost reproduction. Front Endocrinol (Lausanne) (2013) 0.87
Direct binding of the beta1 adrenergic receptor to the cyclic AMP-dependent guanine nucleotide exchange factor CNrasGEF leads to Ras activation. Mol Cell Biol (2002) 0.87
Impaired osteoblast function in GPRC6A null mice. J Bone Miner Res (2010) 0.87
Non-receptor tyrosine kinase Src is required for ischemia-stimulated neuronal cell proliferation via Raf/ERK/CREB activation in the dentate gyrus. BMC Neurosci (2009) 0.87
Cyr61 is regulated by cAMP-dependent protein kinase with serum levels correlating with prostate cancer aggressiveness. Prostate (2011) 0.87
Src-dependent TrkA transactivation is required for pituitary adenylate cyclase-activating polypeptide 38-mediated Rit activation and neuronal differentiation. Mol Biol Cell (2010) 0.86
Role of the mu-opioid receptor in opioid modulation of immune function. Amino Acids (2011) 0.86
Heterotrimeric G protein-dependent WNT-5A signaling to ERK1/2 mediates distinct aspects of microglia proinflammatory transformation. J Neuroinflammation (2012) 0.86
Neural mechanisms of reproduction in females as a predisposing factor for drug addiction. Front Neuroendocrinol (2010) 0.85
Regulated and constitutive activation of specific signalling pathways by the human S1P5 receptor. Br J Pharmacol (2003) 0.85
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