Published in J Lipid Res on July 01, 2001
Genetic variation in ABC transporter A1 contributes to HDL cholesterol in the general population. J Clin Invest (2004) 2.86
Cooperative, ATP-dependent association of the nucleotide binding cassettes during the catalytic cycle of ATP-binding cassette transporters. J Biol Chem (2002) 2.64
Targeted ablation of the abcc6 gene results in ectopic mineralization of connective tissues. Mol Cell Biol (2005) 2.64
Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface. J Clin Invest (2002) 2.02
An ABC transporter controls export of a Drosophila germ cell attractant. Science (2009) 2.02
ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal. Cancer Cell Int (2005) 1.83
Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1. Biochem Pharmacol (2009) 1.75
High density lipoprotein structure-function and role in reverse cholesterol transport. Subcell Biochem (2010) 1.69
The chemical defensome: environmental sensing and response genes in the Strongylocentrotus purpuratus genome. Dev Biol (2006) 1.54
Mechanism of coupling of transport to hydrolysis in bacterial ATP-binding cassette transporters. J Bacteriol (2002) 1.45
ATP-binding cassette (ABC) transporters in normal and pathological lung. Respir Res (2005) 1.37
An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic beta cells. J Clin Invest (2010) 1.36
Overcoming drug resistance in pancreatic cancer. Expert Opin Ther Targets (2011) 1.36
Stimulation of rat erythrocyte P2X7 receptor induces the release of epoxyeicosatrienoic acids. Br J Pharmacol (2007) 1.34
Transcription factors that mediate epithelial-mesenchymal transition lead to multidrug resistance by upregulating ABC transporters. Cell Death Dis (2011) 1.34
ABC transporters in Saccharomyces cerevisiae and their interactors: new technology advances the biology of the ABCC (MRP) subfamily. Microbiol Mol Biol Rev (2009) 1.34
Vanadate-catalyzed photocleavage of the signature motif of an ATP-binding cassette (ABC) transporter. Proc Natl Acad Sci U S A (2002) 1.33
Molecular biology of the blood-brain and the blood-cerebrospinal fluid barriers: similarities and differences. Fluids Barriers CNS (2011) 1.33
Therapy of X-linked adrenoleukodystrophy. NeuroRx (2006) 1.27
Ignicoccus hospitalis and Nanoarchaeum equitans: ultrastructure, cell-cell interaction, and 3D reconstruction from serial sections of freeze-substituted cells and by electron cryotomography. Arch Microbiol (2008) 1.26
Multidrug resistance in fungi. Eukaryot Cell (2007) 1.20
The ABC transporter gene family of Daphnia pulex. BMC Genomics (2009) 1.20
Modulation of the host cell proteome by the intracellular apicomplexan parasite Toxoplasma gondii. Infect Immun (2007) 1.18
The role of ATP-binding cassette transporter A1 in Alzheimer's disease and neurodegeneration. Biochim Biophys Acta (2010) 1.17
The ABCs of sterol transport. J Lipid Res (2008) 1.17
Increased expression of P-glycoprotein and doxorubicin chemoresistance of metastatic breast cancer is regulated by miR-298. Am J Pathol (2012) 1.15
Mutations at arginine 352 alter the pore architecture of CFTR. J Membr Biol (2008) 1.13
Altered profile of secondary metabolites in the root exudates of Arabidopsis ATP-binding cassette transporter mutants. Plant Physiol (2007) 1.13
Principal expression of two mRNA isoforms (ABCB 5alpha and ABCB 5beta ) of the ATP-binding cassette transporter gene ABCB 5 in melanoma cells and melanocytes. Pigment Cell Res (2005) 1.12
Side population cells from human melanoma tumors reveal diverse mechanisms for chemoresistance. J Invest Dermatol (2012) 1.12
Functional analysis of the ATP-binding cassette (ABC) transporter gene family of Tribolium castaneum. BMC Genomics (2013) 1.11
RscA, a member of the MDR1 family of transporters, is repressed by CovR and required for growth of Streptococcus pyogenes under heat stress. J Bacteriol (2006) 1.10
Adipose tissue ATP binding cassette transporter A1 contributes to high-density lipoprotein biogenesis in vivo. Circulation (2011) 1.09
Crizotinib (PF-02341066) reverses multidrug resistance in cancer cells by inhibiting the function of P-glycoprotein. Br J Pharmacol (2012) 1.08
Dynamic ligand-induced conformational rearrangements in P-glycoprotein as probed by fluorescence resonance energy transfer spectroscopy. J Biol Chem (2011) 1.08
Impaired development of atherosclerosis in Abcg1-/- Apoe-/- mice: identification of specific oxysterols that both accumulate in Abcg1-/- Apoe-/- tissues and induce apoptosis. Arterioscler Thromb Vasc Biol (2010) 1.07
ABCG2 transports and transfers heme to albumin through its large extracellular loop. J Biol Chem (2010) 1.06
Sterol transfer by ABCG5 and ABCG8: in vitro assay and reconstitution. J Biol Chem (2006) 1.03
Genome-wide identification and characterization of ATP-binding cassette transporters in the silkworm, Bombyx mori. BMC Genomics (2011) 1.02
Ligand-dependent contribution of RXRbeta to cholesterol homeostasis in Sertoli cells. EMBO Rep (2004) 1.01
Direct and coordinate regulation of ATP-binding cassette transporter genes by Myc factors generates specific transcription signatures that significantly affect the chemoresistance phenotype of cancer cells. J Biol Chem (2010) 1.01
P-glycoprotein retains drug-stimulated ATPase activity upon covalent linkage of the two nucleotide binding domains at their C-terminal ends. J Biol Chem (2011) 1.00
ABCA1 gene variants regulate postprandial lipid metabolism in healthy men. Arterioscler Thromb Vasc Biol (2010) 0.99
Involvement of extracellular vesicle long noncoding RNA (linc-VLDLR) in tumor cell responses to chemotherapy. Mol Cancer Res (2014) 0.99
Localization, regulation, and substrate transport properties of Bpt1p, a Saccharomyces cerevisiae MRP-type ABC transporter. Eukaryot Cell (2002) 0.99
Mutational analysis of threonine 402 adjacent to the GXXXG dimerization motif in transmembrane segment 1 of ABCG2. Biochemistry (2010) 0.96
Opioid analgesics and P-glycoprotein efflux transporters: a potential systems-level contribution to analgesic tolerance. Curr Top Med Chem (2011) 0.96
ABC transporters B1, C1 and G2 differentially regulate neuroregeneration in mice. PLoS One (2012) 0.94
ATP-binding cassette transporter A1 gene polymorphisms and serum lipid levels in young Greek nurses. Lipids Health Dis (2011) 0.93
Requirement of the N-terminal extension for vacuolar trafficking and transport activity of yeast Ycf1p, an ATP-binding cassette transporter. Mol Biol Cell (2002) 0.93
Diversity in ABC transporters: type I, II and III importers. Crit Rev Biochem Mol Biol (2014) 0.93
PDE5 inhibitors, sildenafil and vardenafil, reverse multidrug resistance by inhibiting the efflux function of multidrug resistance protein 7 (ATP-binding Cassette C10) transporter. Cancer Sci (2012) 0.92
In vivo and in vitro multitracer analyses of P-glycoprotein expression-related multidrug resistance. Eur J Nucl Med Mol Imaging (2003) 0.92
Environmental sensing and response genes in cnidaria: the chemical defensome in the sea anemone Nematostella vectensis. Cell Biol Toxicol (2008) 0.92
Cloning of ABCA17, a novel rodent sperm-specific ABC (ATP-binding cassette) transporter that regulates intracellular lipid metabolism. Biochem J (2005) 0.92
Genome-wide identification, characterization and phylogenetic analysis of 50 catfish ATP-binding cassette (ABC) transporter genes. PLoS One (2013) 0.92
Modeling the conformational changes underlying channel opening in CFTR. PLoS One (2013) 0.92
[Pseudoxanthoma elasticum]. Ophthalmologe (2006) 0.92
Combined phylogeny and neighborhood analysis of the evolution of the ABC transporters conferring multiple drug resistance in hemiascomycete yeasts. BMC Genomics (2009) 0.91
Mutational studies of G553 in TM5 of ABCG2: a residue potentially involved in dimerization. Biochemistry (2006) 0.91
Transcriptional responses in honey bee larvae infected with chalkbrood fungus. BMC Genomics (2010) 0.91
Pharmacogenetics: implications for therapy in rheumatic diseases. Nat Rev Rheumatol (2011) 0.90
Role of ALDP (ABCD1) and mitochondria in X-linked adrenoleukodystrophy. Mol Cell Biol (2003) 0.90
Molecular models of human P-glycoprotein in two different catalytic states. BMC Struct Biol (2009) 0.90
Genetic variant of V825I in the ATP-binding cassette transporter A1 gene and serum lipid levels in the Guangxi Bai Ku Yao and Han populations. Lipids Health Dis (2011) 0.90
RNA-Seq reveals different mRNA abundance of transporters and their alternative transcript isoforms during liver development. Toxicol Sci (2012) 0.90
Regulation of ABCA1 functions by signaling pathways. Biochim Biophys Acta (2011) 0.90
Contributions of Aspergillus fumigatus ATP-binding cassette transporter proteins to drug resistance and virulence. Eukaryot Cell (2013) 0.89
A survey of integral alpha-helical membrane proteins. J Struct Funct Genomics (2009) 0.89
Gene and functional up-regulation of the BCRP/ABCG2 transporter in hepatocellular carcinoma. BMC Gastroenterol (2012) 0.89
Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-β production by altering Nicastrin maturation and intracellular localization. J Biol Chem (2011) 0.88
Transporters at CNS barrier sites: obstacles or opportunities for drug delivery? Curr Pharm Des (2014) 0.88
Prognostic impact of multidrug resistance gene expression on the management of breast cancer in the context of adjuvant therapy based on a series of 171 patients. Br J Cancer (2006) 0.88
Characterization of the LSGGQ and H motifs from the Escherichia coli lipid A transporter MsbA. Biochemistry (2006) 0.88
Arginine 383 is a crucial residue in ABCG2 biogenesis. Biochim Biophys Acta (2009) 0.88
Expression and function of ABCG2 in head and neck squamous cell carcinoma and cell lines. Exp Ther Med (2011) 0.88
Loperamide, an FDA-approved antidiarrhea drug, effectively reverses the resistance of multidrug resistant MCF-7/MDR1 human breast cancer cells to doxorubicin-induced cytotoxicity. Cancer Invest (2012) 0.88
EPR spectroscopy of MolB2C2-a reveals mechanism of transport for a bacterial type II molybdate importer. J Biol Chem (2013) 0.87
Retracted Influence of ATP-Binding Cassette Transporters in Root Exudation of Phytoalexins, Signals, and in Disease Resistance. Front Plant Sci (2012) 0.87
Ligand and structure-based classification models for prediction of P-glycoprotein inhibitors. J Chem Inf Model (2014) 0.87
Novel roles for ATP-binding cassette G transporters in lipid redistribution in Toxoplasma. Mol Microbiol (2010) 0.87
An agomir of miR-144-3p accelerates plaque formation through impairing reverse cholesterol transport and promoting pro-inflammatory cytokine production. PLoS One (2014) 0.86
Cholesterol metabolism and homeostasis in the brain. Protein Cell (2015) 0.86
ABCA5 resides in lysosomes, and ABCA5 knockout mice develop lysosomal disease-like symptoms. Mol Cell Biol (2005) 0.86
A new approach to the estimation of functional activity of ABC-transporters regulating intracellular distribution of anticancer drugs using flow cytometry. Dokl Biochem Biophys (2006) 0.86
Regulation of ABC transporter function via phosphorylation by protein kinases. Curr Pharm Biotechnol (2011) 0.86
WHI-P154 enhances the chemotherapeutic effect of anticancer agents in ABCG2-overexpressing cells. Cancer Sci (2014) 0.85
ABC transporters in fish species: a review. Front Physiol (2014) 0.85
Localization and substrate selectivity of sea urchin multidrug (MDR) efflux transporters. J Biol Chem (2012) 0.85
Proteases, cystic fibrosis and the epithelial sodium channel (ENaC). Cell Tissue Res (2012) 0.85
The biology of the germ line in echinoderms. Mol Reprod Dev (2014) 0.84
Circumvention of multi-drug resistance of cancer cells by Chinese herbal medicines. Chin Med (2010) 0.84
The novel ABC transporter ABCH1 is a potential target for RNAi-based insect pest control and resistance management. Sci Rep (2015) 0.83
Expression of the Abca-subfamily of genes in Abcc6-/- mice--upregulation of Abca4. Exp Dermatol (2011) 0.83
Functional hot spots in human ATP-binding cassette transporter nucleotide binding domains. Protein Sci (2010) 0.83
Lentiviral vector-based therapy in head and neck cancer (Review). Oncol Lett (2013) 0.83
KATP Channels in the Cardiovascular System. Physiol Rev (2016) 0.82
Expression pattern of human ATP-binding cassette transporters in skin. Pharmacol Res Perspect (2013) 0.82
Semi-synthetic ocotillol analogues as selective ABCB1-mediated drug resistance reversal agents. Oncotarget (2015) 0.82
The secretory route of the leaderless protein interleukin 1beta involves exocytosis of endolysosome-related vesicles. Mol Biol Cell (1999) 3.24
High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1. Proc Natl Acad Sci U S A (2000) 2.64
Transport of lipids from golgi to plasma membrane is defective in tangier disease patients and Abc1-deficient mice. Nat Genet (2000) 2.26
ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine. Nat Cell Biol (2000) 2.25
Molecular cloning of the human ATP-binding cassette transporter 1 (hABC1): evidence for sterol-dependent regulation in macrophages. Biochem Biophys Res Commun (1999) 2.08
The ATP binding cassette transporter ABC1, is required for the engulfment of corpses generated by apoptotic cell death. EMBO J (1996) 1.69
Interleukin-1beta secretion is impaired by inhibitors of the Atp binding cassette transporter, ABC1. Blood (1997) 1.67
Cloning of two novel ABC transporters mapping on human chromosome 9. Genomics (1994) 1.63
A novel coding sequence belonging to a new multicopy gene family mapping within the human MHC class I region. Immunogenetics (1993) 1.47
Human ATP-binding cassette transporter 1 (ABC1): genomic organization and identification of the genetic defect in the original Tangier disease kindred. Proc Natl Acad Sci U S A (1999) 1.42
A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern. Proc Natl Acad Sci U S A (1996) 1.39
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Hepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDL. J Clin Invest (2001) 1.28
Engulfment of apoptotic cells involves the redistribution of membrane phosphatidylserine on phagocyte and prey. Nat Cell Biol (1999) 1.27
Complete genomic sequence of the human ABCA1 gene: analysis of the human and mouse ATP-binding cassette A promoter. Proc Natl Acad Sci U S A (2000) 1.26
The phagocytosis of apoptotic cells. Semin Immunol (2001) 1.21
A two-step mechanism for free cholesterol and phospholipid efflux from human vascular cells to apolipoprotein A-1. Biochemistry (2000) 1.14
CpG islands and HTF islands in the HLA class I region: investigation of the methylation status of class I genes leads to precise physical mapping of the HLA-B and -C genes. Nucleic Acids Res (1988) 1.13
ABC1, an ATP binding cassette transporter required for phagocytosis of apoptotic cells, generates a regulated anion flux after expression in Xenopus laevis oocytes. J Biol Chem (1997) 1.11
Specific docking of apolipoprotein A-I at the cell surface requires a functional ABCA1 transporter. J Biol Chem (2001) 1.05
Molecular cloning of a mammalian ABC transporter homologous to Drosophila white gene. Mamm Genome (1996) 1.01
The ABCA subclass of mammalian transporters. Biochim Biophys Acta (1999) 0.97
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Endogenous PTX3 translocates at the membrane of late apoptotic human neutrophils and is involved in their engulfment by macrophages. Cell Death Differ (2008) 0.96
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Hybrid genes between HLA-A2 and HLA-A3 constructed by in vivo recombination allow mapping of HLA-A2 and HLA-A3 polymorphic antigenic determinants. J Immunol (1988) 0.86
ABC1, the mammalian homologue of the engulfment gene ced-7, is required during phagocytosis of both necrotic and apoptotic cells. Biochem Soc Trans (1998) 0.85
Comparative analysis of the promoter structure and genomic organization of the human and mouse ABCA7 gene encoding a novel ABCA transporter. Cytogenet Cell Genet (2001) 0.85
Isolation and chromosomal mapping of a novel ATP-binding cassette transporter conserved in mouse and human. Genomics (1997) 0.85
Characteristics of bacteriocins produced by Klebsiella bacilli. Arch Immunol Ther Exp (Warsz) (1967) 0.85
HLA-E is the only class I gene that escapes CpG methylation and is transcriptionally active in the trophoblast-derived human cell line JAR. Immunogenetics (1993) 0.84
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Engulfing by lipids: a matter of taste? Cell Death Differ (2001) 0.77
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Membrane degradation of receptor bound insulin. Influence of glipizide. Minerva Endocrinol (1985) 0.75
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[New technics for sterilization of bacteriocin preparations]. Ann Inst Pasteur (Paris) (1966) 0.75
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