Phosphorylation of Mcm4 at specific sites by cyclin-dependent kinase leads to loss of Mcm4,6,7 helicase activity.

Eukaryotic MCM proteins: beyond replication initiation. Microbiol Mol Biol Rev (2004) 4.19

The Mcm complex: unwinding the mechanism of a replicative helicase. Microbiol Mol Biol Rev (2009) 2.29

Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency. J Clin Invest (2012) 1.35

Genomic instability in cancer. Cold Spring Harb Perspect Biol (2013) 1.23

Identification of a G(2) arrest domain in the E1 wedge E4 protein of human papillomavirus type 16. J Virol (2002) 1.21

Cyclin/CDK regulates the nucleocytoplasmic localization of the human papillomavirus E1 DNA helicase. J Virol (2004) 1.15

Phosphorylation of MCM4 at sites inactivating DNA helicase activity of the MCM4-MCM6-MCM7 complex during Epstein-Barr virus productive replication. J Virol (2006) 1.13

Human cytomegalovirus infection leads to accumulation of geminin and inhibition of the licensing of cellular DNA replication. J Virol (2003) 1.11

Interplay between S-cyclin-dependent kinase and Dbf4-dependent kinase in controlling DNA replication through phosphorylation of yeast Mcm4 N-terminal domain. Mol Biol Cell (2008) 1.11

Simian virus 40 activates ATR-Delta p53 signaling to override cell cycle and DNA replication control. J Virol (2010) 1.03

Intra-S-phase checkpoint activation by direct CDK2 inhibition. Mol Cell Biol (2004) 1.01

Domain within the helicase subunit Mcm4 integrates multiple kinase signals to control DNA replication initiation and fork progression. Proc Natl Acad Sci U S A (2014) 0.95

Phosphorylation of Mcm2 modulates Mcm2-7 activity and affects the cell's response to DNA damage. Nucleic Acids Res (2011) 0.90

Functional cooperation between FACT and MCM is coordinated with cell cycle and differential complex formation. J Biomed Sci (2010) 0.86

Mcm2 phosphorylation and the response to replicative stress. BMC Genet (2012) 0.85

Multi-step loading of human minichromosome maintenance proteins in live human cells. J Biol Chem (2013) 0.85

MCM Paradox: Abundance of Eukaryotic Replicative Helicases and Genomic Integrity. Mol Biol Int (2014) 0.85

The role of APC/C(Cdh1) in replication stress and origin of genomic instability. Oncogene (2015) 0.82

Visualization of the MCM DNA helicase at replication factories before the onset of DNA synthesis. Chromosoma (2012) 0.82

Interactions of the human MCM-BP protein with MCM complex components and Dbf4. PLoS One (2012) 0.81

Phosphorylation of minichromosome maintenance protein 7 (MCM7) by cyclin/cyclin-dependent kinase affects its function in cell cycle regulation. J Biol Chem (2013) 0.78

Geminin functions downstream of p53 in K-ras-induced gene amplification of dihydrofolate reductase. Cancer Res (2012) 0.77

Genome wide comparative comprehensive analysis of Plasmodium falciparum MCM family with human host. Commun Integr Biol (2012) 0.76

Electron microscopic observation and single-stranded DNA binding activity of the Mcm4,6,7 complex. J Mol Biol (2000) 1.24

Inhibition of Mcm4,6,7 helicase activity by phosphorylation with cyclin A/Cdk2. J Biol Chem (2000) 1.10

Biochemical activities associated with mouse Mcm2 protein. J Biol Chem (2001) 0.94