Published in J Biol Chem on July 17, 2001
The GSK3-like kinase BIN2 phosphorylates and destabilizes BZR1, a positive regulator of the brassinosteroid signaling pathway in Arabidopsis. Proc Natl Acad Sci U S A (2002) 3.26
Characterization and identification of microRNA core promoters in four model species. PLoS Comput Biol (2007) 2.86
NR4A orphan nuclear receptors: transcriptional regulators of gene expression in metabolism and vascular biology. Arterioscler Thromb Vasc Biol (2010) 1.53
The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells. Mol Biol Cell (2007) 1.53
Alteration of large-scale chromatin structure by estrogen receptor. Mol Cell Biol (2002) 1.36
MicroRNA-27a Indirectly Regulates Estrogen Receptor {alpha} Expression and Hormone Responsiveness in MCF-7 Breast Cancer Cells. Endocrinology (2010) 1.26
ESR1 mutations—a mechanism for acquired endocrine resistance in breast cancer. Nat Rev Clin Oncol (2015) 1.22
Thiol-disulfide redox dependence of heme binding and heme ligand switching in nuclear hormone receptor rev-erb{beta}. J Biol Chem (2010) 1.11
Nuclear Receptors in Regulation of Mouse ES Cell Pluripotency and Differentiation. PPAR Res (2007) 1.00
Chemopreventive n-3 fatty acids activate RXRalpha in colonocytes. Carcinogenesis (2003) 1.00
Androgen receptor (AR) expression is an independent unfavorable prognostic factor in gastric cancer. J Cancer Res Clin Oncol (2004) 0.99
iNR-PhysChem: a sequence-based predictor for identifying nuclear receptors and their subfamilies via physical-chemical property matrix. PLoS One (2012) 0.99
The emerging role of nuclear receptor RORalpha and its crosstalk with LXR in xeno- and endobiotic gene regulation. Exp Biol Med (Maywood) (2008) 0.97
Orphan nuclear receptors as targets for drug development. Pharm Res (2010) 0.97
The potential role of lycopene for the prevention and therapy of prostate cancer: from molecular mechanisms to clinical evidence. Int J Mol Sci (2013) 0.95
Activation of xenobiotic receptors: driving into the nucleus. Expert Opin Drug Metab Toxicol (2010) 0.92
Identification and regulation of novel PPAR-gamma splice variants in human THP-1 macrophages. Biochim Biophys Acta (2006) 0.91
Nuclear Receptors and Clearance of Apoptotic Cells: Stimulating the Macrophage's Appetite. Front Immunol (2014) 0.89
Ligand unbinding pathways from the vitamin D receptor studied by molecular dynamics simulations. Eur Biophys J (2008) 0.87
Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors. J Biol Chem (2012) 0.87
Alzheimer's disease: relevant molecular and physiopathological events affecting amyloid-β brain balance and the putative role of PPARs. Front Aging Neurosci (2014) 0.86
Nonsteroidal bivalent estrogen ligands: an application of the bivalent concept to the estrogen receptor. ACS Chem Biol (2013) 0.86
Regulation of ABC efflux transporters at blood-brain barrier in health and neurological disorders. Brain Res (2015) 0.85
BRCA1 inhibits AR-mediated proliferation of breast cancer cells through the activation of SIRT1. Sci Rep (2016) 0.84
Coactivation of estrogen receptor alpha (ER alpha)/Sp1 by vitamin D receptor interacting protein 150 (DRIP150). Arch Biochem Biophys (2007) 0.83
The Effect of Baicalin as A PPAR Activator on Erythroid Differentiation of CD133(+)Hematopoietic Stem Cells in Umbilical Cord Blood. Cell J (2015) 0.83
Cholestasis. Gut (2003) 0.82
Modulation of xenobiotic receptors by steroids. Molecules (2013) 0.82
Chaperones and the maturation of steroid hormone receptor complexes. Oncotarget (2011) 0.81
A coregulatory network of NR2F1 and microRNA-140. PLoS One (2013) 0.81
Human ADA3 regulates RARalpha transcriptional activity through direct contact between LxxLL motifs and the receptor coactivator pocket. Nucleic Acids Res (2010) 0.81
Dietary modulation of inflammation-induced colorectal cancer through PPARγ. PPAR Res (2009) 0.80
Retinoic acid decreases adherence of murine myeloid dendritic cells and increases production of matrix metalloproteinase-9. J Nutr (2008) 0.80
In silico and in vivo analysis of binding affinity of estrogens with estrogen receptor alpha in Channa punctatus (Bloch). Fish Physiol Biochem (2014) 0.79
Design, synthesis, and biological evaluation of indenoisoquinoline rexinoids with chemopreventive potential. J Med Chem (2013) 0.79
RORα binds to E2F1 to inhibit cell proliferation and regulate mammary gland branching morphogenesis. Mol Cell Biol (2014) 0.78
Differential regulation of CYP3A4 promoter activity by a new class of natural product derivatives binding to pregnane X receptor. Biochem Pharmacol (2013) 0.78
Isomer specificity of conjugated linoleic acid (CLA): 9E,11E-CLA. Nutr Res Pract (2008) 0.76
Conjugated linoleic acid isomers modulate protein expression profile in rat hepatocytes. Genes Nutr (2012) 0.76
ONRLDB-manually curated database of experimentally validated ligands for orphan nuclear receptors: insights into new drug discovery. Database (Oxford) (2015) 0.76
Linoleic and α-linolenic fatty acid consumption over three generations exert cumulative regulation of hepatic expression of genes related to lipid metabolism. Genes Nutr (2014) 0.76
Computational characterization of modes of transcriptional regulation of nuclear receptor genes. PLoS One (2014) 0.76
The cellular membrane as a mediator for small molecule interaction with membrane proteins. Biochim Biophys Acta (2016) 0.75
Anti-Transcription Factor RNA Aptamers as Potential Therapeutics. Nucleic Acid Ther (2015) 0.75
Exploration of the Hypothalamic-Pituitary-Adrenal Axis to Improve Animal Welfare by Means of Genetic Selection: Lessons from the South African Merino. Animals (Basel) (2013) 0.75
Endogenous Nur77 Is a Specific Indicator of Antigen Receptor Signaling in Human T and B Cells. J Immunol (2016) 0.75
A Structural Investigation into Oct4 Regulation by Orphan Nuclear Receptors, Germ Cell Nuclear Factor (GCNF) and Liver Receptor Homolog-1 (LRH-1). J Mol Biol (2016) 0.75
Transmembrane helices in "classical" nuclear reproductive steroid receptors: a perspective. Nucl Recept Signal (2015) 0.75
Postprandial molecular responses in the liver of the barramundi, Lates calcarifer. Fish Physiol Biochem (2013) 0.75