Published in Proc Natl Acad Sci U S A on July 17, 2001
Collaboration of homologous recombination and nonhomologous end-joining factors for the survival and integrity of mice and cells. Genes Dev (2004) 1.77
A palindrome-mediated mechanism distinguishes translocations involving LCR-B of chromosome 22q11.2. Hum Mol Genet (2003) 1.67
A large AZFc deletion removes DAZ3/DAZ4 and nearby genes from men in Y haplogroup N. Am J Hum Genet (2003) 1.62
A mechanism of palindromic gene amplification in Saccharomyces cerevisiae. Genes Dev (2005) 1.45
Fusion of nearby inverted repeats by a replication-based mechanism leads to formation of dicentric and acentric chromosomes that cause genome instability in budding yeast. Genes Dev (2009) 1.25
Rapid, stabilizing palindrome rearrangements in somatic cells by the center-break mechanism. Mol Cell Biol (2003) 1.21
A novel recombination pathway initiated by the Mre11/Rad50/Nbs1 complex eliminates palindromes during meiosis in Schizosaccharomyces pombe. Genetics (2005) 1.21
Spontaneous mitotic homologous recombination at an enhanced yellow fluorescent protein (EYFP) cDNA direct repeat in transgenic mice. Proc Natl Acad Sci U S A (2003) 1.12
Meiotic recombination and spatial proximity in the etiology of the recurrent t(11;22). Am J Hum Genet (2006) 1.05
The transposon Galileo generates natural chromosomal inversions in Drosophila by ectopic recombination. PLoS One (2009) 0.99
A method for cloning and sequencing long palindromic DNA junctions. Nucleic Acids Res (2004) 0.95
Molecular characterization and chromosomal distribution of Galileo, Kepler and Newton, three foldback transposable elements of the Drosophila buzzatii species complex. Genetics (2005) 0.94
Methods to determine DNA structural alterations and genetic instability. Methods (2009) 0.90
Species-specific typing of DNA based on palindrome frequency patterns. DNA Res (2011) 0.84
DNA secondary structure at chromosomal fragile sites in human disease. Curr Genomics (2015) 0.82
The yin and yang of repair mechanisms in DNA structure-induced genetic instability. Mutat Res (2012) 0.82
Strand invasion and DNA synthesis from the two 3' ends of a double-strand break in Mammalian cells. Genetics (2003) 0.81
A mechanism of gene amplification driven by small DNA fragments. PLoS Genet (2012) 0.81
Statistical Enrichment of Epigenetic States Around Triplet Repeats that Can Undergo Expansions. Front Neurosci (2016) 0.75
Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (1999) 19.25
Homology-directed repair is a major double-strand break repair pathway in mammalian cells. Proc Natl Acad Sci U S A (1998) 5.37
The mouse Spo11 gene is required for meiotic chromosome synapsis. Mol Cell (2000) 5.16
Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells. EMBO J (2000) 4.94
Double-strand break repair by interchromosomal recombination: suppression of chromosomal translocations. Genes Dev (1998) 4.68
Chromosome synapsis defects and sexually dimorphic meiotic progression in mice lacking Spo11. Mol Cell (2000) 4.47
Trinucleotide repeats that expand in human disease form hairpin structures in vitro. Cell (1995) 4.35
Meiosis: how could it work? Proc Natl Acad Sci U S A (1996) 3.40
Long DNA palindromes, cruciform structures, genetic instability and secondary structure repair. Bioessays (1994) 2.91
Expansions and contractions in a tandem repeat induced by double-strand break repair. Mol Cell Biol (1998) 2.79
Coupled homologous and nonhomologous repair of a double-strand break preserves genomic integrity in mammalian cells. Mol Cell Biol (2000) 2.57
The SbcCD nuclease of Escherichia coli is a structural maintenance of chromosomes (SMC) family protein that cleaves hairpin DNA. Proc Natl Acad Sci U S A (1998) 2.47
Regions of genomic instability on 22q11 and 11q23 as the etiology for the recurrent constitutional t(11;22). Hum Mol Genet (2000) 2.47
Spermatid-specific expression of protamine 1 in transgenic mice. Proc Natl Acad Sci U S A (1987) 2.36
AT-rich palindromes mediate the constitutional t(11;22) translocation. Am J Hum Genet (2000) 2.21
Palindrome resolution and recombination in the mammalian germ line. Mol Cell Biol (1997) 2.17
Hairpins are formed by the single DNA strands of the fragile X triplet repeats: structure and biological implications. Proc Natl Acad Sci U S A (1995) 2.10
Inverted Alu repeats unstable in yeast are excluded from the human genome. EMBO J (2000) 2.01
Biased distribution of inverted and direct Alus in the human genome: implications for insertion, exclusion, and genome stability. Genome Res (2001) 1.97
Recombination by replication. Cell (1996) 1.96
Factors affecting inverted repeat stimulation of recombination and deletion in Saccharomyces cerevisiae. Genetics (1998) 1.78
One-sided invasion events in homologous recombination at double-strand breaks. Mutat Res (1994) 1.67
Instability of long inverted repeats within mouse transgenes. EMBO J (1996) 1.67
A 140-bp-long palindromic sequence induces double-strand breaks during meiosis in the yeast Saccharomyces cerevisiae. Genetics (1997) 1.57
Recombination-induced CAG trinucleotide repeat expansions in yeast involve the MRE11-RAD50-XRS2 complex. EMBO J (2000) 1.56
Yeast ARMs (DNA at-risk motifs) can reveal sources of genome instability. Mutat Res (1998) 1.53
The intrinsically unstable life of DNA triplet repeats associated with human hereditary disorders. Prog Nucleic Acid Res Mol Biol (2001) 1.44
P nucleotide insertions and the resolution of hairpin DNA structures in mammalian cells. Proc Natl Acad Sci U S A (1994) 1.42
Palindromes as substrates for multiple pathways of recombination in Escherichia coli. Genetics (2000) 1.38
Genetic instabilities in (CTG.CAG) repeats occur by recombination. J Biol Chem (1999) 1.37
Long palindromic sequences induce double-strand breaks during meiosis in yeast. Mol Cell Biol (2000) 1.22
The effects of trinucleotide repeats found in human inherited disorders on palindrome inviability in Escherichia coli suggest hairpin folding preferences in vivo. Genetics (1995) 1.10
Gene conversion (recombination) mediates expansions of CTG[middle dot]CAG repeats. J Biol Chem (2000) 1.01
Palindromic DNA and genome stability. Further studies. Ann N Y Acad Sci (1999) 1.00
Gene conversion in mitotically dividing cells: a view from Drosophila. Trends Genet (1998) 0.97
Palindromy is eliminated through a structure-specific recombination process in rodent cells. Nucleic Acids Res (1999) 0.96
Analysis of Escherichia coli beta-galactosidase expression in transgenic mice by flow cytometry of sperm. Proc Natl Acad Sci U S A (1992) 0.88
XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. Genes Dev (1999) 9.50
Brca1 controls homology-directed DNA repair. Mol Cell (1999) 7.82
Recombinational DNA double-strand breaks in mice precede synapsis. Nat Genet (2001) 6.91
BRCA2 is required for homology-directed repair of chromosomal breaks. Mol Cell (2001) 6.75
Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease. Mol Cell Biol (1994) 6.08
Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells. Genes Dev (2001) 5.60
Homology-directed repair is a major double-strand break repair pathway in mammalian cells. Proc Natl Acad Sci U S A (1998) 5.37
Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells. Proc Natl Acad Sci U S A (1994) 5.37
Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells. EMBO J (2000) 4.94
Double-strand break repair by interchromosomal recombination: suppression of chromosomal translocations. Genes Dev (1998) 4.68
Chromosome synapsis defects and sexually dimorphic meiotic progression in mice lacking Spo11. Mol Cell (2000) 4.47
Gene conversion tracts from double-strand break repair in mammalian cells. Mol Cell Biol (1998) 4.46
Deletion of an essential gene in Escherichia coli by site-specific recombination with linear DNA fragments. J Bacteriol (1984) 4.30
Frequent chromosomal translocations induced by DNA double-strand breaks. Nature (2000) 3.27
Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination. Nature (1999) 3.24
Cycloheximide resistance in yeast: the gene and its protein. Nucleic Acids Res (1983) 3.02
Chromosomal double-strand break repair in Ku80-deficient cells. Proc Natl Acad Sci U S A (1996) 2.91
Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation. Cancer Res (2001) 2.76
A long and complex enhancer activates transcription of the gene coding for the highly abundant immediate early mRNA in murine cytomegalovirus. Proc Natl Acad Sci U S A (1985) 2.74
Mouse RAD54 affects DNA double-strand break repair and sister chromatid exchange. Mol Cell Biol (2000) 2.66
Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells. Mol Cell Biol (1998) 2.60
Coupled homologous and nonhomologous repair of a double-strand break preserves genomic integrity in mammalian cells. Mol Cell Biol (2000) 2.57
Double-strand breaks and tumorigenesis. Trends Cell Biol (2001) 2.53
Ku80-deficient cells exhibit excess degradation of extrachromosomal DNA. J Biol Chem (1996) 2.40
Double-strand-break-induced homologous recombination in mammalian cells. Biochem Soc Trans (2001) 2.36
Double-strand breaks at the target locus stimulate gene targeting in embryonic stem cells. Nucleic Acids Res (1995) 2.36
Loss of heterozygosity induced by a chromosomal double-strand break. Proc Natl Acad Sci U S A (1997) 2.17
Palindrome resolution and recombination in the mammalian germ line. Mol Cell Biol (1997) 2.17
High frequency of homologous recombination in mammalian cells between endogenous and introduced SV40 genomes. Cell (1985) 2.14
Modular arrangement of functional domains along the sequence of an aminoacyl tRNA synthetase. Nature (1984) 2.04
Genetic analysis of the DNA-dependent protein kinase reveals an inhibitory role of Ku in late S-G2 phase DNA double-strand break repair. J Biol Chem (2001) 1.73
Repair of double-strand breaks by homologous recombination in mismatch repair-defective mammalian cells. Mol Cell Biol (2001) 1.68
A mouse homolog of the Saccharomyces cerevisiae meiotic recombination DNA transesterase Spo11p. Genomics (1999) 1.65
Double-strand breaks and translocations in cancer. Cell Mol Life Sci (2002) 1.60
Chromosome healing in mouse embryonic stem cells. Proc Natl Acad Sci U S A (1999) 1.55
Dispensable pieces of an aminoacyl tRNA synthetase which activate the catalytic site. Cell (1984) 1.28
Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stages. Exp Cell Res (2006) 1.09
Transmeiotic differentiation of male germ cells in culture. Cell (1993) 1.04
A double-strand break in a chromosomal LINE element can be repaired by gene conversion with various endogenous LINE elements in mouse cells. Mol Cell Biol (2000) 1.03
Chromosomal double-strand breaks introduced in mammalian cells by expression of I-Sce I endonuclease. Methods Mol Biol (1999) 1.01
Palindromic DNA and genome stability. Further studies. Ann N Y Acad Sci (1999) 1.00
NHEJ deficiency and disease. Mol Cell (2001) 0.90
Two mutations in the dispensable part of alanine tRNA synthetase which affect the catalytic activity. J Biol Chem (1985) 0.87
Recombination between two chromosomes: implications for genomic integrity in mammalian cells. Cold Spring Harb Symp Quant Biol (2000) 0.86
A model for testing recombinogenic sequences in the mouse germline. Hum Mol Genet (1996) 0.84
Amino acid replacements that compensate for a large polypeptide deletion in an enzyme. Science (1985) 0.84
Studies on the influence of cytosine methylation on DNA recombination and end-joining in mammalian cells. J Biol Chem (1995) 0.83
Size polymorphism and the structure of aminoacyl-tRNA synthetases. Fed Proc (1984) 0.81
Extrachromosomal assay for DNA double-strand break repair. Methods Mol Biol (1999) 0.80
Homologous recombination between heterologs during repair of a double-strand break. Suppression of translocations in normal cells. Ann N Y Acad Sci (1999) 0.79