Published in Stem Cells on January 01, 2001
Core transcriptional regulatory circuitry in human embryonic stem cells. Cell (2005) 34.93
Growth factors essential for self-renewal and expansion of mouse spermatogonial stem cells. Proc Natl Acad Sci U S A (2004) 4.77
Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells. Mol Cell Biol (2005) 4.54
Oct4 distribution and level in mouse clones: consequences for pluripotency. Genes Dev (2002) 3.52
Alternative splicing events identified in human embryonic stem cells and neural progenitors. PLoS Comput Biol (2007) 2.71
Isolation of male germ-line stem cells; influence of GDNF. Dev Biol (2005) 2.40
Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development. Mol Cell Biol (2003) 2.40
Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development. Mol Cell Biol (2005) 2.32
Conservation of spermatogonial stem cell self-renewal signaling between mouse and rat. Proc Natl Acad Sci U S A (2005) 2.28
Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells. Genes Dev (2009) 2.18
Isolation of a novel population of multipotent adult stem cells from human hair follicles. Am J Pathol (2006) 2.13
Newer insights into premeiotic development of germ cells in adult human testis using Oct-4 as a stem cell marker. J Histochem Cytochem (2010) 1.92
Reorganization of enhancer patterns in transition from naive to primed pluripotency. Cell Stem Cell (2014) 1.81
Concise review: isoforms of OCT4 contribute to the confusing diversity in stem cell biology. Stem Cells (2010) 1.74
G9a and Jhdm2a regulate embryonic stem cell fusion-induced reprogramming of adult neural stem cells. Stem Cells (2008) 1.68
Human embryonic and neuronal stem cell markers in retinoblastoma. Mol Vis (2007) 1.66
Hyaluronan-CD44v3 interaction with Oct4-Sox2-Nanog promotes miR-302 expression leading to self-renewal, clonal formation, and cisplatin resistance in cancer stem cells from head and neck squamous cell carcinoma. J Biol Chem (2012) 1.57
The embryonic stem cell transcription factors Oct-4 and FoxD3 interact to regulate endodermal-specific promoter expression. Proc Natl Acad Sci U S A (2002) 1.52
Epigenetic memory of active gene transcription is inherited through somatic cell nuclear transfer. Proc Natl Acad Sci U S A (2005) 1.50
Identification of an OCT4 and SRY regulatory module using integrated computational and experimental genomics approaches. Genome Res (2007) 1.50
Embryonic stem cells markers SOX2, OCT4 and Nanog expression and their correlations with epithelial-mesenchymal transition in nasopharyngeal carcinoma. PLoS One (2013) 1.41
Embryonic stem cell differentiation: a chromatin perspective. Reprod Biol Endocrinol (2003) 1.37
Dppa3 / Pgc7 / stella is a maternal factor and is not required for germ cell specification in mice. BMC Dev Biol (2004) 1.35
Pyruvate kinase M2 regulates glucose metabolism by functioning as a coactivator for hypoxia-inducible factor 1 in cancer cells. Oncotarget (2011) 1.33
Effects of ectopic Nanog and Oct4 overexpression on mesenchymal stem cells. Stem Cells Dev (2009) 1.32
Simplifying gene trees for easier comprehension. BMC Bioinformatics (2006) 1.30
Selective apoptosis of pluripotent mouse and human stem cells by novel ceramide analogues prevents teratoma formation and enriches for neural precursors in ES cell-derived neural transplants. J Cell Biol (2004) 1.29
Toward the identification of a "renopoietic system"? Stem Cells (2009) 1.27
Oct4A is expressed by a subpopulation of prostate neuroendocrine cells. Prostate (2009) 1.25
Side population in adult murine epidermis exhibits phenotypic and functional characteristics of keratinocyte stem cells. Proc Natl Acad Sci U S A (2006) 1.22
Regulation of cell death in mitotic neural progenitor cells by asymmetric distribution of prostate apoptosis response 4 (PAR-4) and simultaneous elevation of endogenous ceramide. J Cell Biol (2003) 1.22
Metformin represses self-renewal of the human breast carcinoma stem cells via inhibition of estrogen receptor-mediated OCT4 expression. PLoS One (2011) 1.19
Phosphorylation regulates human OCT4. Proc Natl Acad Sci U S A (2012) 1.19
Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes. Cell Rep (2014) 1.14
Side population cells in the mouse thyroid exhibit stem/progenitor cell-like characteristics. Endocrinology (2007) 1.13
MAPK/ERK signalling mediates VEGF-induced bone marrow stem cell differentiation into endothelial cell. J Cell Mol Med (2008) 1.13
The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation. J Cell Sci (2009) 1.12
Oct-4 controls cell-cycle progression of embryonic stem cells. Biochem J (2010) 1.12
Role of Oct4 in maintaining and regaining stem cell pluripotency. Stem Cell Res Ther (2010) 1.12
The role of engineered tendon matrix in the stemness of tendon stem cells in vitro and the promotion of tendon-like tissue formation in vivo. Biomaterials (2011) 1.11
In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach. BMC Genomics (2009) 1.09
Reagentless, electrochemical approach for the specific detection of double- and single-stranded DNA binding proteins. Anal Chem (2009) 1.08
Very small embryonic-like stem cells: implications in reproductive biology. Biomed Res Int (2013) 1.07
Targeting Aggressive Cancer Stem Cells in Glioblastoma. Front Oncol (2015) 1.05
Oct-3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β-catenin signalling. EMBO J (2010) 1.05
Specific detection of OCT3/4 isoform A/B/B1 expression in solid (germ cell) tumours and cell lines: confirmation of OCT3/4 specificity for germ cell tumours. Br J Cancer (2011) 1.05
Amnion-derived stem cells: in quest of clinical applications. Stem Cell Res Ther (2011) 1.05
The Oct4 protein: more than a magic stemness marker. Am J Stem Cells (2014) 1.05
Establishment of totipotency does not depend on Oct4A. Nat Cell Biol (2013) 1.05
Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3. BMC Dev Biol (2008) 1.02
Transcriptional regulation of the Oct4 gene, a master gene for pluripotency. Histol Histopathol (2010) 1.01
CXXC finger protein 1 contains redundant functional domains that support embryonic stem cell cytosine methylation, histone methylation, and differentiation. Mol Cell Biol (2009) 1.00
Nuclear Receptors in Regulation of Mouse ES Cell Pluripotency and Differentiation. PPAR Res (2007) 1.00
Very small embryonic-like stem cells are involved in pancreatic regeneration and their dysfunction with age may lead to diabetes and cancer. Stem Cell Res Ther (2015) 0.99
Regulative germ cell specification in axolotl embryos: a primitive trait conserved in the mammalian lineage. Philos Trans R Soc Lond B Biol Sci (2003) 0.99
Keeping mtDNA in shape between generations. PLoS Genet (2014) 0.98
Cdk2ap1 is required for epigenetic silencing of Oct4 during murine embryonic stem cell differentiation. J Biol Chem (2008) 0.98
Construction and validation of a regulatory network for pluripotency and self-renewal of mouse embryonic stem cells. PLoS Comput Biol (2014) 0.97
Gold nanoparticle-based surface-enhanced Raman scattering for noninvasive molecular probing of embryonic stem cell differentiation. PLoS One (2011) 0.96
Enhanced proliferation and differentiation of Oct4- and Sox2-overexpressing human adipose tissue mesenchymal stem cells. Exp Mol Med (2014) 0.94
Role of Oct4 in the early embryo development. Cell Regen (Lond) (2014) 0.94
Phenotypical and ultrastructural features of Oct4-positive cells in the adult mouse lung. J Cell Mol Med (2014) 0.94
Human tendon stem cells better maintain their stemness in hypoxic culture conditions. PLoS One (2013) 0.93
Sequential counteracting kinases restrict an asymmetric gene expression program to early G1. Mol Biol Cell (2010) 0.93
Nuclear reprogramming in mammalian somatic cell nuclear cloning. Cytogenet Genome Res (2004) 0.92
Expression of OCT4 in human esophageal squamous cell carcinoma is significantly associated with poorer prognosis. World J Gastroenterol (2012) 0.92
The oncogene c-Jun impedes somatic cell reprogramming. Nat Cell Biol (2015) 0.91
Dedifferentiation derived cells exhibit phenotypic and functional characteristics of epidermal stem cells. J Cell Mol Med (2010) 0.90
Initial colony morphology-based selection for iPS cells derived from adult fibroblasts is substantially improved by temporary UTF1-based selection. PLoS One (2010) 0.90
PPARgamma2 Regulates a Molecular Signature of Marrow Mesenchymal Stem Cells. PPAR Res (2007) 0.90
Tip110 maintains expression of pluripotent factors in and pluripotency of human embryonic stem cells. Stem Cells Dev (2012) 0.90
Snail contributes to the maintenance of stem cell-like phenotype cells in human pancreatic cancer. PLoS One (2014) 0.90
CD117(+) amniotic fluid stem cells: state of the art and future perspectives. Organogenesis (2012) 0.89
Oct4 is required ~E7.5 for proliferation in the primitive streak. PLoS Genet (2013) 0.89
Octamer-binding transcription factors: genomics and functions. Front Biosci (Landmark Ed) (2013) 0.88
Platelet-rich plasma promotes the proliferation of human muscle derived progenitor cells and maintains their stemness. PLoS One (2013) 0.88
Cloning and Characterization of 3.1kb Promoter Region of the Oct4 Gene from the Fischer 344 Rat. Open Stem Cell J (2009) 0.88
The topographical regulation of embryonic stem cell differentiation. Philos Trans R Soc Lond B Biol Sci (2004) 0.87
BMP induction of cardiogenesis in P19 cells requires prior cell-cell interaction(s). Dev Dyn (2006) 0.87
Differentiation of murine embryonic stem cells induces progesterone receptor gene expression. Exp Cell Res (2005) 0.87
Ectopic expression of GATA6 bypasses requirement for Grb2 in primitive endoderm formation. Dev Dyn (2010) 0.85
Development of antibodies to human embryonic stem cell antigens. BMC Dev Biol (2005) 0.85
Markers of stem cells in human ovarian granulosa cells: is there a clinical significance in ART? J Ovarian Res (2012) 0.85
Assessment of stem cell markers during long-term culture of mouse embryonic stem cells. Cytotechnology (2004) 0.85
Epigenetic dynamics during preimplantation development. Reproduction (2015) 0.85
The maintenance of pluripotency following laser direct-write of mouse embryonic stem cells. Biomaterials (2010) 0.85
Oxidized low density lipoprotein, stem cells, and atherosclerosis. Lipids Health Dis (2012) 0.85
Ox-LDL modifies the behaviour of bone marrow stem cells and impairs their endothelial differentiation via inhibition of Akt phosphorylation. J Cell Mol Med (2011) 0.85
JMJD3 as an epigenetic regulator in development and disease. Int J Biochem Cell Biol (2015) 0.85
In vitro and in vivo study of human amniotic fluid-derived stem cell differentiation into myogenic lineage. Clin Exp Med (2010) 0.85
Wdr74 is required for blastocyst formation in the mouse. PLoS One (2011) 0.85
Identification and characterisation of the early differentiating cells in neural differentiation of human embryonic stem cells. PLoS One (2012) 0.84
Oct4-induced reprogramming is required for adult brain neural stem cell differentiation into midbrain dopaminergic neurons. PLoS One (2011) 0.84
Expression of the pluripotency markers Oct3/4, Nanog and Sox2 in human breast cancer cell lines. Oncol Lett (2012) 0.84
Self/nonself perception, reproduction and the extended MHC. Self Nonself (2010) 0.84
Increased multi-drug resistance and reduced apoptosis in osteosarcoma side population cells are crucial factors for tumor recurrence. Exp Ther Med (2016) 0.83
OCT-4 expression in follicular and luteal phase endometrium: a pilot study. Reprod Biol Endocrinol (2010) 0.83
Spatial and temporal distribution of Oct-4 and acetylated H4K5 in rabbit embryos. Reprod Biomed Online (2012) 0.83
The Dynamics of Global Chromatin Remodeling are Pivotal for Tracking the Normal Pluripotency of Human Embryonic Stem Cells. Anat Physiol (2012) 0.83
Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells. Development (1996) 7.00
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Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation. Dev Biol (1994) 3.88
Germline-specific expression of the Oct-4/green fluorescent protein (GFP) transgene in mice. Dev Growth Differ (1999) 3.56
New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2. Genes Dev (1998) 3.43
Cell type-specific transcriptional enhancement in vitro requires the presence of trans-acting factors. EMBO J (1985) 2.70
A transcription factor which binds to the enhancers of SV40, immunoglobulin heavy chain and U2 snRNA genes. Nature (1987) 2.48
Mouse germline restriction of Oct4 expression by germ cell nuclear factor. Dev Cell (2001) 2.27
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Modulation of the activity of multiple transcriptional activation domains by the DNA binding domains mediates the synergistic action of Sox2 and Oct-3 on the fibroblast growth factor-4 enhancer. J Biol Chem (2000) 2.04
Comparative analysis of human, bovine, and murine Oct-4 upstream promoter sequences. Mamm Genome (2001) 1.89
Simplified generation of targeting constructs using ET recombination. Nucleic Acids Res (1999) 1.79
In line with our ancestors: Oct-4 and the mammalian germ. Bioessays (1998) 1.79
Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles. EMBO J (1997) 1.73
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Reduced fertility and spermatogenesis defects in mice lacking chromosomal protein Hmgb2. Development (2001) 1.63
Oct-4: control of totipotency and germline determination. Mol Reprod Dev (2000) 1.57
Differential dimer activities of the transcription factor Oct-1 by DNA-induced interface swapping. Mol Cell (2001) 1.50
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Mouse Oct-1 contains a composite homeodomain of human Oct-1 and Oct-2. Nucleic Acids Res (1993) 1.07
Phage display screening reveals an association between germline-specific transcription factor Oct-4 and multiple cellular proteins. J Mol Biol (2000) 0.99
Crystallization of redox-insensitive Oct1 POU domain with different DNA-response elements. Acta Crystallogr D Biol Crystallogr (2001) 0.97
Synergism with germ line transcription factor Oct-4: viral oncoproteins share the ability to mimic a stem cell-specific activity. Mol Cell Biol (1999) 0.92
A transcription factor interacting with the class I gene enhancer is inactive in tumorigenic cell lines which suppress major histocompatibility complex class I genes. Mol Cell Biol (1990) 0.90
Binding of Sp1 and Sp3 transcription factors to the Oct-4 gene promoter. Cell Mol Biol (Noisy-le-grand) (1999) 0.90
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Laser secondary neutral mass spectrometry for copper detection in micro-scale biopsies. J Mass Spectrom (2009) 0.87
Distinct populations of tumor-initiating cells derived from a tumor generated by rat mammary cancer stem cells. Proc Natl Acad Sci U S A (2008) 0.83
Oct-4: more than just a POUerful marker of the mammalian germline? APMIS (1998) 0.83
Cell-cell fusion as a means to establish pluripotency. Ernst Schering Res Found Workshop (2006) 0.82
Repression of Oct-4 during embryonic cell differentiation correlates with the appearance of TRIF, a transiently induced DNA-binding factor. Cell Mol Biol (Noisy-le-grand) (1999) 0.79
Recombinant human albumin supports development of somatic cell nuclear transfer embryos in mice: toward the establishment of a chemically defined cloning protocol. Cloning Stem Cells (2006) 0.75
Derivation of germ cells from embryonic stem cells. Ernst Schering Res Found Workshop (2006) 0.75
Bcar3 is expressed in sertoli cells and germ cells of the developing testis in mice. Sex Dev (2011) 0.75