Published in Int J Cancer on August 20, 2001
Cytokines in radiobiological responses: a review. Radiat Res (2012) 1.29
Mitigation of radiation-induced lung injury by genistein and EUK-207. Int J Radiat Biol (2011) 1.10
Intraesophageal administration of GS-nitroxide (JP4-039) protects against ionizing irradiation-induced esophagitis. In Vivo (2010) 1.05
Radioprotection in vitro and in vivo by minicircle plasmid carrying the human manganese superoxide dismutase transgene. Hum Gene Ther (2008) 1.04
Endothelial targeting of antibody-decorated polymeric filomicelles. ACS Nano (2011) 1.03
Targeted modulation of reactive oxygen species in the vascular endothelium. J Control Release (2011) 0.97
Enhanced expression of mitochondrial superoxide dismutase leads to prolonged in vivo cell cycle progression and up-regulation of mitochondrial thioredoxin. Free Radic Biol Med (2010) 0.94
Strategies for discovery of small molecule radiation protectors and radiation mitigators. Front Oncol (2012) 0.92
Heavy ions, radioprotectors and genomic instability: implications for human space exploration. Radiat Environ Biophys (2009) 0.91
Irradiated esophageal cells are protected from radiation-induced recombination by MnSOD gene therapy. Radiat Res (2010) 0.89
Enhancing the antitumor activity of adriamycin and ionizing radiation. Cancer Res (2009) 0.88
Antioxidant-chemoprevention diet ameliorates late effects of total-body irradiation and supplements radioprotection by MnSOD-plasmid liposome administration. Radiat Res (2011) 0.87
New approaches to radiation protection. Front Oncol (2015) 0.85
Modulation of in utero total body irradiation induced newborn mouse growth retardation by maternal manganese superoxide dismutase-plasmid liposome (MnSOD-PL) gene therapy. Gene Ther (2011) 0.82
Cell cycle regulators guide mitochondrial activity in radiation-induced adaptive response. Antioxid Redox Signal (2014) 0.81
The zebrafish--Danio rerio--is a useful model for measuring the effects of small-molecule mitigators of late effects of ionizing irradiation. In Vivo (2012) 0.78
Effectiveness of combined modality radiotherapy of orthotopic human squamous cell carcinomas in Nu/Nu mice using cetuximab, tirapazamine and MnSOD-plasmid liposome gene therapy. In Vivo (2010) 0.78
GST-TAT-SOD: Cell Permeable Bifunctional Antioxidant Enzyme-A Potential Selective Radioprotector. Oxid Med Cell Longev (2016) 0.78
Radioprotection by short-term oxidative preconditioning: role of manganese superoxide dismutase. FEBS Lett (2009) 0.77
Role of the esophageal vagus neural pathway in ionizing irradiation-induced seizures in nitric oxide synthase-1 homologous recombinant negative NOS1-/- mice. In Vivo (2011) 0.76
Antioxidant Approaches to Management of Ionizing Irradiation Injury. Antioxidants (Basel) (2015) 0.75
Gene therapy for radioprotection. Cancer Gene Ther (2015) 0.75
Current status of tumor radiogenic therapy. World J Gastroenterol (2005) 0.75
In Vivo Radioprotective Activity of Cell-Permeable Bifunctional Antioxidant Enzyme GST-TAT-SOD against Whole-Body Ionizing Irradiation in Mice. Oxid Med Cell Longev (2017) 0.75
Radiation-Induced Oral Mucositis. Front Oncol (2017) 0.75
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science (2000) 8.56
Bone marrow as a potential source of hepatic oval cells. Science (1999) 8.52
The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling. Cell (1992) 8.20
Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts. Genes Dev (1993) 7.41
Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling. Nature (1993) 6.38
Nucleolar Arf sequesters Mdm2 and activates p53. Nat Cell Biol (1999) 5.78
Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2. Science (1993) 5.02
Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins. Science (1986) 4.99
Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras. Nature (1993) 4.54
The structural basis of the activation of Ras by Sos. Nature (1998) 4.50
A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway. Cell (1997) 4.43
Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis. Am J Physiol Lung Cell Mol Physiol (2008) 3.80
Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines. Proc Natl Acad Sci U S A (1983) 3.76
Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation. Cell (1985) 3.73
RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase. Science (1996) 3.30
Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization. Curr Biol (1997) 3.22
Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis. J Exp Med (1991) 3.21
Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS. Science (1996) 3.18
Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos. Science (1998) 3.17
Multiple biologic activities of a cloned inducer T-cell population. Proc Natl Acad Sci U S A (1981) 2.95
A prospective, randomized, controlled evaluation of peripheral nerve stimulation versus standard clinical dosing of neuromuscular blocking agents in critically ill patients. Crit Care Med (1997) 2.76
Inhibition of ras-induced proliferation and cellular transformation by p16INK4. Science (1995) 2.42
Signal transduction through the EGF receptor transfected in IL-3-dependent hematopoietic cells. Science (1988) 2.29
Functional changes in human leukemic cell line HL-60. A model for myeloid differentiation. J Cell Biol (1979) 2.28
Hepatic oval cells express the hematopoietic stem cell marker Thy-1 in the rat. Hepatology (1998) 2.21
Elevated levels of S-nitrosoalbumin in preeclampsia plasma. Circ Res (2001) 2.21
Results of treatment of 127 patients with systemic histiocytosis. Medicine (Baltimore) (1981) 2.17
G-protein beta gamma-subunits activate the cardiac muscarinic K+-channel via phospholipase A2. Nature (1989) 2.14
Two forms of transforming growth factor-beta distinguished by multipotential haematopoietic progenitor cells. Nature (1987) 2.13
An SH3 binding region in the epithelial Na+ channel (alpha rENaC) mediates its localization at the apical membrane. EMBO J (1994) 2.10
Identification of a novel Rac1-interacting protein involved in membrane ruffling. EMBO J (1996) 2.00
Sensitivity of corticosteroid-dependent insulin-resistant lipogenesis in marrow preadipocytes of obese-diabetic (db/db) mice. Nature (1978) 1.88
Mechanisms of pulmonary toxicity and medical applications of carbon nanotubes: Two faces of Janus? Pharmacol Ther (2008) 1.85
Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein. Cell (1998) 1.77
Differential activation of the Rac pathway by Ha-Ras and K-Ras. J Biol Chem (2001) 1.72
Structure-based mutagenesis reveals distinct functions for Ras switch 1 and switch 2 in Sos-catalyzed guanine nucleotide exchange. J Biol Chem (2001) 1.71
The Ras superfamily of GTPases. FASEB J (1996) 1.70
Site-specific incorporation of a phosphotyrosine mimetic reveals a role for tyrosine phosphorylation of SHP-2 in cell signaling. Mol Cell (2001) 1.68
Phenotypic characteristics of cell lines requiring interleukin 3 for growth. J Immunol (1982) 1.67
Role of beta 1 and beta 2 integrins in the adhesion of human CD34hi stem cells to bone marrow stroma. J Clin Invest (1992) 1.65
Identification of the mitogen-activated protein kinase phosphorylation sites on human Sos1 that regulate interaction with Grb2. Mol Cell Biol (1996) 1.63
The role of lipid peroxidation in pathogenesis of ischemic damage and the antioxidant protection of the heart. Basic Res Cardiol (1983) 1.60
Constitutive and inducible granulocyte-macrophage functions in mouse, rat, and human myeloid leukemia-derived continuous tissue culture lines. Cancer Res (1978) 1.59
Oxidative stress and inflammatory response in dermal toxicity of single-walled carbon nanotubes. Toxicology (2008) 1.58
The role of the PH domain in the signal-dependent membrane targeting of Sos. EMBO J (1997) 1.54
Histiocytosis-X. N Engl J Med (1981) 1.51
Kinase suppressor of Ras inhibits the activation of extracellular ligand-regulated (ERK) mitogen-activated protein (MAP) kinase by growth factors, activated Ras, and Ras effectors. J Biol Chem (1998) 1.48
In vitro induction of continuous acute promyelocytic leukemia cell lines by Friend or Abelson murine leukemia virus. Blood (1979) 1.48
Regulation of Sos activity by intramolecular interactions. Mol Cell Biol (1998) 1.46
Rac1 mediates STAT3 activation by autocrine IL-6. Proc Natl Acad Sci U S A (2001) 1.46
A multicenter phase II study of cetuximab in combination with chest radiotherapy and consolidation chemotherapy in patients with stage III non-small cell lung cancer. Lung Cancer (2013) 1.43
Cell-cell adhesion mediated by binding of membrane-anchored transforming growth factor alpha to epidermal growth factor receptors promotes cell proliferation. Proc Natl Acad Sci U S A (1990) 1.40
Inhibition of Ras-induced DNA synthesis by expression of the phosphatase MKP-1. Science (1994) 1.40
Ras effectors and their role in mitogenesis and oncogenesis. J Mol Med (Berl) (1997) 1.40
Independent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathways. Proc Natl Acad Sci U S A (1989) 1.39
Radiation therapy in children: continued need to assess risk versus gain. Int J Radiat Oncol Biol Phys (1992) 1.38
Evidence for structured variation in self-renewal capacity within long-term bone marrow cultures. Proc Natl Acad Sci U S A (1980) 1.38
A Rac1 effector site controlling mitogenesis through superoxide production. J Biol Chem (1998) 1.35
Structural and dynamic membrane properties of alpha-tocopherol and alpha-tocotrienol: implication to the molecular mechanism of their antioxidant potency. Biochemistry (1993) 1.30
Decreased pulmonary radiation resistance of manganese superoxide dismutase (MnSOD)-deficient mice is corrected by human manganese superoxide dismutase-Plasmid/Liposome (SOD2-PL) intratracheal gene therapy. Radiat Res (2000) 1.28
Induction of mouse type-C RNA virus by lipopolysaccharide. J Immunol (1975) 1.28
Granulopoiesis longevity in continuous bone marrow cultures and factor-dependent cell line generation: significant variation among 28 inbred mouse strains and outbred stocks. J Natl Cancer Inst (1982) 1.28
Interleukin 3-dependent hematopoietic progenitor cell lines. Fed Proc (1983) 1.27
Suppression of Ras-induced apoptosis by the Rac GTPase. Mol Cell Biol (1999) 1.26
Modulation of radiation-induced cytokine elevation associated with esophagitis and esophageal stricture by manganese superoxide dismutase-plasmid/liposome (SOD2-PL) gene therapy. Radiat Res (2001) 1.26
Oxidative stress following traumatic brain injury in rats: quantitation of biomarkers and detection of free radical intermediates. J Neurochem (2000) 1.26
Genotoxicity of carbon nanofibers: are they potentially more or less dangerous than carbon nanotubes or asbestos? Toxicol Appl Pharmacol (2011) 1.25
Intratracheal injection of manganese superoxide dismutase (MnSOD) plasmid/liposomes protects normal lung but not orthotopic tumors from irradiation. Gene Ther (2000) 1.23
Engraftment of a clonal bone marrow stromal cell line in vivo stimulates hematopoietic recovery from total body irradiation. Proc Natl Acad Sci U S A (1987) 1.21
Morphologic revertants of murine sarcoma virus transformed nonproducer BALB-3T3: selective techniques for isolation and biologic properties in vitro and in vivo. Virology (1974) 1.20
Dissociation of opsonized particle phagocytosis and respiratory burst activity in an Epstein-Barr virus-infected myeloid cell line. J Cell Biol (1980) 1.19
Multimodality therapy for malignant mesothelioma based on a study of natural history. Am J Med (1980) 1.19
The role of nanotoxicology in realizing the 'helping without harm' paradigm of nanomedicine: lessons from studies of pulmonary effects of single-walled carbon nanotubes. J Intern Med (2010) 1.19
Effect of tunicamycin, an inhibitor of protein glycosylation, on the biological properties of acetylcholine receptor in cultured muscle cells. J Biol Chem (1983) 1.18
Apoptotic interactions of cytochrome c: redox flirting with anionic phospholipids within and outside of mitochondria. Biochim Biophys Acta (2006) 1.15
Murine sarcoma viruses block corticosteroid-induced differentiation of bone marrow preadipocytes associated with long-term in vitro hemopoiesis. Virology (1979) 1.13
Co-capping of ras proteins with surface immunoglobulins in B lymphocytes. Nature (1990) 1.12
Redox gene therapy protects human IB-3 lung epithelial cells against ionizing radiation-induced apoptosis. Hum Gene Ther (1998) 1.12
Intratracheal injection of adenovirus containing the human MnSOD transgene protects athymic nude mice from irradiation-induced organizing alveolitis. Int J Radiat Oncol Biol Phys (1999) 1.11
Granulocyte-macrophage colony-stimulating factor and tetradecanoyl phorbol acetate induce a distinct, restricted subset of primary-response TIS genes in both proliferating and terminally differentiated myeloid cells. Mol Cell Biol (1989) 1.11
Oncogenicity of an endogenous C-type virus chemically activated from mouse cells in culture. J Virol (1974) 1.10
Mechanisms of muscle stem cell expansion with cytokines. Stem Cells (2002) 1.10
Different hematological diseases induced by type C viruses chemically activated from embryo cells of different mouse strains. Cancer Res (1975) 1.10
The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association of diffuse B cell lymphoma and pleckstrin homology domains. J Biol Chem (1997) 1.10
Differential interactions of human Sos1 and Sos2 with Grb2. J Biol Chem (1995) 1.10
Activation of Ras and other signaling pathways by receptor tyrosine kinases. Cold Spring Harb Symp Quant Biol (1994) 1.09
Cell phenotype specific kinetics of expression of intratracheally injected manganese superoxide dismutase-plasmid/liposomes (MnSOD-PL) during lung radioprotective gene therapy. Gene Ther (2003) 1.08
Release of spleen focus-forming virus (SFFV) from differentiation inducible promyelocytic leukemia cell lines transformed in vitro by Friend leukemia virus. Virology (1980) 1.08
Increased accumulation of neutrophils and decreased fibrosis in the lung of NADPH oxidase-deficient C57BL/6 mice exposed to carbon nanotubes. Toxicol Appl Pharmacol (2008) 1.08
Phospholipid signaling in apoptosis: peroxidation and externalization of phosphatidylserine. Toxicology (2000) 1.07
Prevention of irradiation-induced esophagitis by plasmid/liposome delivery of the human manganese superoxide dismutase transgene. Radiat Oncol Investig (1999) 1.07
Modeling stem cell population growth: incorporating terms for proliferative heterogeneity. Stem Cells (2003) 1.06
Redistribution of phosphatidylethanolamine and phosphatidylserine precedes reperfusion-induced apoptosis. Am J Physiol (1998) 1.05
Milk fat globule epidermal growth factor 8 (MFG-E8) binds to oxidized phosphatidylserine: implications for macrophage clearance of apoptotic cells. Cell Death Differ (2004) 1.05
Cytoplasmic metallothionein overexpression protects NIH 3T3 cells from tert-butyl hydroperoxide toxicity. J Biol Chem (1994) 1.04
Biological characterization of cloned permanent stromal cell lines from anemic Sl/Sld mice and +/+ littermates. Exp Hematol (1987) 1.04
Inhalation delivery of manganese superoxide dismutase-plasmid/liposomes protects the murine lung from irradiation damage. Gene Ther (2005) 1.03