Assembly of gap junction channels: mechanism, effects of calmodulin antagonists and identification of connexin oligomerization determinants.

PubWeight™: 1.06‹?› | Rank: Top 15%

🔗 View Article (PMID 11502216)

Published in Eur J Biochem on August 01, 2001

Authors

S Ahmad1, P E Martin, W H Evans

Author Affiliations

1: Department of Medical Biochemistry, University of Wales College of Medicine, Heath Park, Cardiff, Wales, UK.

Articles citing this

The gap junction cellular internet: connexin hemichannels enter the signalling limelight. Biochem J (2006) 2.24

CMTX1 patients' cells present genomic instability corrected by CamKII inhibitors. Orphanet J Rare Dis (2015) 1.41

Specific heterodimer formation is a prerequisite for uroplakins to exit from the endoplasmic reticulum. Mol Biol Cell (2002) 1.33

Critical role of the first transmembrane domain of Cx26 in regulating oligomerization and function. Mol Biol Cell (2012) 0.92

Molecular interaction and functional regulation of connexin50 gap junctions by calmodulin. Biochem J (2011) 0.92

Gating of connexin 43 gap junctions by a cytoplasmic loop calmodulin binding domain. Am J Physiol Cell Physiol (2012) 0.90

Different domains are critical for oligomerization compatibility of different connexins. Biochem J (2011) 0.89

Post-translational integration and oligomerization of connexin 26 in plasma membranes and evidence of formation of membrane pores: implications for the assembly of gap junctions. Biochem J (2002) 0.88

CamKII inhibitors reduce mitotic instability, connexon anomalies and progression of the in vivo behavioral phenotype in transgenic animals expressing a mutated Gjb1 gene. Front Neurosci (2014) 0.88

The role of Connexin 46 promoter in lens and other hypoxic tissues. Commun Integr Biol (2012) 0.82

Calmodulin antagonists suppress gap junction coupling in isolated Hensen cells of the guinea pig cochlea. Pflugers Arch (2003) 0.82

The Cx43-like connexin protein Cx40.8 is differentially localized during fin ontogeny and fin regeneration. PLoS One (2012) 0.79

Is the voltage gate of connexins CO2-sensitive? Cx45 channels and inhibition of calmodulin expression. J Membr Biol (2003) 0.78

A cataract-causing connexin 50 mutant is mislocalized to the ER due to loss of the fourth transmembrane domain and cytoplasmic domain. FEBS Open Bio (2012) 0.76

CMTX Disorder and CamKinase. Front Cell Neurosci (2016) 0.75

Connexinopathies: a structural and functional glimpse. BMC Cell Biol (2016) 0.75

Articles by these authors

The Anti-Neuritic Bases of Vegetable Origin in relationship to Beri-Beri, with a Method of Isolation of Torulin the Anti-Neuritic Base of Yeast. Biochem J (1912) 17.48

Functional polarity of the rat hepatocyte surface membrane. Isolation and characterization of plasma-membrane subfractions from the blood-sinusoidal, bile-Canalicular and contiguous surfaces of the hepatocyte. Biochem J (1975) 2.62

Topological analysis of the major protein in isolated intact rat liver gap junctions and gap junction-derived single membrane structures. J Biol Chem (1987) 2.30

Fractionation of liver plasma membranes prepared by zonal centrifugation. Biochem J (1970) 2.27

Central role of heterocellular gap junctional communication in endothelium-dependent relaxations of rabbit arteries. J Physiol (1998) 2.08

Properties of a 5'-nucleotidase purified from mouse liver plasma membranes. Biochem J (1973) 1.85

Purification of myeloperoxidases from the bone marrow of the guinea pig. Biochemistry (1969) 1.84

Connexin mimetic peptides reversibly inhibit Ca(2+) signaling through gap junctions in airway cells. Am J Physiol Lung Cell Mol Physiol (2000) 1.83

Subtilisin Carlsberg. V. The complete sequence; comparison with subtilisin BPN'; evolutionary relationships. J Biol Chem (1968) 1.79

The endothelial component of cannabinoid-induced relaxation in rabbit mesenteric artery depends on gap junctional communication. J Physiol (1999) 1.69

Insulin binding to rat liver Golgi fractions. J Cell Biol (1973) 1.65

Differential expression of connexins during neocortical development and neuronal circuit formation. J Neurosci (1997) 1.60

The complete amino acid sequence of two types of subtilisin, BPN' and Carlsberg. J Biol Chem (1966) 1.58

The lipid composition of plasma membrane subfractions originating from the three major functional domains of the rat hepatocyte cell surface. Biochim Biophys Acta (1976) 1.55

Environmental and demographic risk factors for egg allergy in a population-based study of infants. Allergy (2012) 1.53

Peptides homologous to extracellular loop motifs of connexin 43 reversibly abolish rhythmic contractile activity in rabbit arteries. J Physiol (1997) 1.51

The effect of polystyrene beads on cyclic 3',5'-adenosine monophosphate concentration in leukocytes. J Clin Invest (1971) 1.49

Targeting motifs and functional parameters governing the assembly of connexins into gap junctions. Biochem J (2000) 1.45

Inhibition of the gap junctional component of endothelium-dependent relaxations in rabbit iliac artery by 18-alpha glycyrrhetinic acid. Br J Pharmacol (1998) 1.43

Separation of bone marrow cells by sedimentation at unit gravity. Nature (1967) 1.41

Preparation and properties of nexuses and lipid-enriched vesicles from mouse liver plasma membranes. Biochem J (1972) 1.41

pH in the endosome. Measurements during pinocytosis and receptor-mediated endocytosis. Exp Cell Res (1984) 1.41

Wales is not part of England! Science (2002) 1.40

Guinea pig heterophil and eosinophil peroxidase. Arch Biochem Biophys (1972) 1.35

Smallpox Handler's Lung. Proc R Soc Med (1963) 1.32

Gap junctional communication underpins EDHF-type relaxations evoked by ACh in the rat hepatic artery. Am J Physiol Heart Circ Physiol (2001) 1.31

Proteoglycan-degrading enzymes. A radiochemical assay method and the detection of a new enzyme cathepsin F. Biochem J (1977) 1.30

Properties of connexin26 gap junctional proteins derived from mutations associated with non-syndromal heriditary deafness. Hum Mol Genet (1999) 1.30

Transverse organization of phospholipids across the bilayer of plasma-membrane subfractions of rat hepatocytes. Biochem J (1978) 1.30

Specific motifs in the external loops of connexin proteins can determine gap junction formation between chick heart myocytes. J Physiol (1995) 1.29

Purification and properties of a mouse liver plasma-membrane glycoprotein hydrolysing nucleotide pyrophosphate and phosphodiester bonds. Biochem J (1973) 1.29

Nucleotide pyrophosphatase, a sialoglycoprotein located on the hepatocyte surface. Nature (1974) 1.28

Role of heterocellular Gap junctional communication in endothelium-dependent smooth muscle hyperpolarization: inhibition by a connexin-mimetic peptide. Biochem Biophys Res Commun (1999) 1.27

A biochemical dissection of the functional polarity of the plasma membrane of the hepatocyte. Biochim Biophys Acta (1980) 1.26

Receptor-rich intracellular membrane vesicles transporting asialotransferrin and insulin in liver. Nature (1982) 1.24

Multiple pathways in the trafficking and assembly of connexin 26, 32 and 43 into gap junction intercellular communication channels. J Cell Sci (2001) 1.22

Assembly of chimeric connexin-aequorin proteins into functional gap junction channels. Reporting intracellular and plasma membrane calcium environments. J Biol Chem (1998) 1.22

Factors affecting running economy. Sports Med (1989) 1.21

Assembly of hepatic gap junctions. Topography and distribution of connexin 32 in intracellular and plasma membranes determined using sequence-specific antibodies. J Biol Chem (1993) 1.20

Connexin 32 of gap junctions contains two cytoplasmic calmodulin-binding domains. Biochem J (1997) 1.19

Distribution of liver plasma membrane 5' nucleotidase as indicated by its reaction with anti-plasma membrane serum. Arch Biochem Biophys (1974) 1.18

Role of membranes in bile formation. Comparison of the composition of bile and a liver bile-canalicular plasma-membrane subfraction. Biochem J (1976) 1.17

Connexin 43 hemichannels contribute to the propagation of apoptotic cell death in a rat C6 glioma cell model. Cell Death Differ (2008) 1.17

Purification and properties of cytidine deaminase from normal and leukemic granulocytes. J Clin Invest (1974) 1.16

Blood lead concentrations and lead intake in children of different ethnic origin. Hum Toxicol (1985) 1.16

Intercellular calcium waves in HeLa cells expressing GFP-labeled connexin 43, 32, or 26. Mol Biol Cell (2000) 1.15

Nitric oxide-independent relaxations to acetylcholine and A23187 involve different routes of heterocellular communication. Role of Gap junctions and phospholipase A2. Circ Res (1999) 1.15

Separation of granulocytes, monocytes, lymphocytes, erythrocytes, and platelets from human blood and relative tagging with diisopropylfluorophosphate (DFP). J Lab Clin Med (1969) 1.15

A novel missense mutation in GJB2 disturbs gap junction protein transport and causes focal palmoplantar keratoderma with deafness. J Med Genet (2007) 1.13

Functional analysis of amino acid sequences in connexin43 involved in intercellular communication through gap junctions. J Cell Sci (1995) 1.13

Topography of connexin32 in rat liver gap junctions. Evidence for an intramolecular disulphide linkage connecting the two extracellular peptide loops. J Cell Sci (1991) 1.13

Preparation of plasma-membrane subfractions from isolated rat hepatocytes. Biochem J (1977) 1.11

Biosynthesis of liver membranes. Incorporation of ( 3 H)leucine into proteins and of ( 14 C)glucosamine into proteins and lipids of liver microsomal and plasma-membrane fractions. Biochem J (1971) 1.11

Subfractionation of hepatic endosomes in Nycodenz gradients and by free-flow electrophoresis. Separation of ligand-transporting and receptor-enriched membranes. Biochem J (1985) 1.10

Relative rates of degradation of mouse-liver surface-membrane proteins. Eur J Biochem (1973) 1.09

Phospholipid, cholesterol, polypeptide and glycoprotein composition of hepatic endosome subfractions. Biochem J (1985) 1.08

Porcine aortic endothelial gap junctions: identification and permeation by caged InsP3. J Cell Sci (1996) 1.08

Characteristic patterns of gait in the healthy old. Ann N Y Acad Sci (1988) 1.08

Gap junctions in the adult cerebral cortex: regional differences in their distribution and cellular expression of connexins. J Comp Neurol (1996) 1.07

Assembly of heteromeric connexons in guinea-pig liver en route to the Golgi apparatus, plasma membrane and gap junctions. Eur J Biochem (1999) 1.04

Enrichment of cell types from the rat adenohypophysis by sedimentation at unit gravity. Endocrinology (1973) 1.04

Role of gap junctions in endothelium-derived hyperpolarizing factor responses and mechanisms of K(+)-relaxation. Eur J Pharmacol (2000) 1.03

Intercellular communication in the immune system: differential expression of connexin40 and 43, and perturbation of gap junction channel functions in peripheral blood and tonsil human lymphocyte subpopulations. Immunology (2000) 1.03

Intracellular trafficking pathways in the assembly of connexins into gap junctions. J Biol Chem (1999) 1.03

Intercellular Ca2+ signaling in alveolar epithelial cells through gap junctions and by extracellular ATP. Am J Physiol Lung Cell Mol Physiol (2001) 1.03

Walking symmetry and energy cost in persons with unilateral transtibial amputations: matching prosthetic and intact limb inertial properties. Arch Phys Med Rehabil (2000) 1.02

The contribution of lead in water to dietary lead intakes. J Sci Food Agric (1981) 1.02

Preparation of a gap junction fraction from uteri of pregnant rats: the 28-kD polypeptides of uterus, liver, and heart gap junctions are homologous. J Cell Biol (1985) 1.02

The relationship between cadence and lower extremity EMG in cyclists and noncyclists. Med Sci Sports Exerc (1995) 1.01

Studies on the distribution of some histocompatibility antigens in mouse liver plasma membrane and microsomal fractions. Immunology (1970) 1.01

Factors influencing myeloperoxidase and catalase activities in polymorphonuclear leukocytes. Biochim Biophys Acta (1967) 1.01

Distribution of G-proteins in rat liver plasma-membrane domains and endocytic pathways. Biochem J (1989) 1.01

Gap junctions and connexin expression in the inner ear. Novartis Found Symp (1999) 1.00

Fractionation of granule proteins of granulocytes by copper chelate chromatography. Biochim Biophys Acta (1979) 1.00

Location of nucleotide pyrophosphatase and alkaline phosphodiesterase activities on the lymphocyte surface membrane. Biochem J (1976) 1.00

Gap26, a connexin mimetic peptide, inhibits currents carried by connexin43 hemichannels and gap junction channels. Pharmacol Res (2012) 1.00

Connexin expression in Huntington's diseased human brain. Cell Biol Int (1998) 1.00

Biogenesis of hepatocyte plasma-membrane domains. Incorporation of (3H)fucose into plasma-membrane and golgi-apparatus glycoproteins. Biochem J (1980) 1.00

Analysis of gap junction assembly using mutated connexins detected in Charcot-Marie-Tooth X-linked disease. J Neurochem (2000) 1.00

Synthesis and assembly of connexins in vitro into homomeric and heteromeric functional gap junction hemichannels. Biochem J (1999) 0.99

Developmental expression and assembly of connexins into homomeric and heteromeric gap junction hemichannels in the mouse mammary gland. J Cell Physiol (2000) 0.98

The distribution of surface antigens during fractionation of mouse liver plasma membranes. Biochem J (1972) 0.98

Preferential localization of rat liver D-myo-inositol 1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase in bile-canalicular plasma membrane and 'late' endosomal vesicles. Biochem J (1988) 0.98

The HealthNuts population-based study of paediatric food allergy: validity, safety and acceptability. Clin Exp Allergy (2010) 0.98

Preparation of hepatic gap (communicating) junctions. Identification of the constituent polypeptide subunits. Biochem J (1977) 0.96

The effect of carried loads on the walking patterns of men and women. Ergonomics (1986) 0.96

Ten kilometer performance and predicted velocity at VO2max among well-trained male runners. Med Sci Sports Exerc (1989) 0.95

Glycoproteins of mouse liver smooth microsomal and plasma membrane fractions. Biochim Biophys Acta (1970) 0.95

A biochemical dissection of the cardiac intercalated disk: isolation of subcellular fractions containing fascia adherentes and gap junctions. J Cell Sci (1981) 0.95

Variability in running economy and mechanics among trained male runners. Med Sci Sports Exerc (1991) 0.95

Effect of cycling experience, aerobic power, and power output on preferred and most economical cycling cadences. Med Sci Sports Exerc (1997) 0.94

Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness. Nat Nanotechnol (2011) 0.94

Hepatic endosome fractions contain an ATP-driven proton pump. Biochem J (1985) 0.94

Priority targeting of glycosyl-phosphatidylinositol-anchored proteins to the bile-canalicular (apical) plasma membrane of hepatocytes. Involvement of 'late' endosomes. Biochem J (1990) 0.93

Sequence-specific antibodies to connexins block intercellular calcium signaling through gap junctions. Cell Calcium (1998) 0.93

Estimating segment inertial properties: comparison of magnetic resonance imaging with existing methods. J Biomech (1990) 0.93