Published in J Exp Med on August 20, 2001
The pathophysiology of IgA nephropathy. J Am Soc Nephrol (2011) 2.27
IgA glycosylation and IgA immune complexes in the pathogenesis of IgA nephropathy. Semin Nephrol (2008) 1.64
Secretory IgA mediates retrotranscytosis of intact gliadin peptides via the transferrin receptor in celiac disease. J Exp Med (2007) 1.43
Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia. J Exp Med (2010) 1.39
Pathogenesis of IgA nephropathy. Nat Rev Nephrol (2012) 1.22
Heterologous protection induced by the inner capsid proteins of rotavirus requires transcytosis of mucosal immunoglobulins. J Virol (2002) 1.18
Immunopathogenesis of IgAN. Semin Immunopathol (2007) 1.16
Involvement of Fc receptors in disorders of the central nervous system. Neuromolecular Med (2009) 1.15
Functional flexibility of intestinal IgA - broadening the fine line. Front Immunol (2012) 1.13
Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia. Nat Med (2011) 1.09
Glycosylation of IgA1 and pathogenesis of IgA nephropathy. Semin Immunopathol (2012) 1.09
Transglutaminase is essential for IgA nephropathy development acting through IgA receptors. J Exp Med (2012) 1.08
New developments in the genetics, pathogenesis, and therapy of IgA nephropathy. Kidney Int (2015) 1.04
Immunoglobulin heavy chain constant regions regulate immunity and tolerance to idiotypes of antibody variable regions. Proc Natl Acad Sci U S A (2002) 1.02
Analysis of IgA1 N-glycosylation and its contribution to FcalphaRI binding. Biochemistry (2008) 1.00
Immunomodulatory properties of human serum immunoglobulin A: anti-inflammatory and pro-inflammatory activities in human monocytes and peripheral blood mononuclear cells. Clin Exp Immunol (2005) 0.97
Biologics for the treatment of autoimmune renal diseases. Nat Rev Nephrol (2016) 0.97
New insights into the pathogenesis of IgA nephropathy. Semin Immunopathol (2014) 0.96
The IgA1 immune complex-mediated activation of the MAPK/ERK kinase pathway in mesangial cells is associated with glomerular damage in IgA nephropathy. Kidney Int (2012) 0.95
Sphingomyelin synthase 1-generated sphingomyelin plays an important role in transferrin trafficking and cell proliferation. J Biol Chem (2011) 0.90
Mesangial cell-specific antibodies are central to the pathogenesis of lupus nephritis. Clin Dev Immunol (2011) 0.88
Primary breast cancer tumours contain high amounts of IgA1 immunoglobulin: an immunohistochemical analysis of a possible carrier of the tumour-associated Tn antigen. PLoS One (2013) 0.87
Role of IgA and IgA fc receptors in inflammation. J Clin Immunol (2009) 0.87
Henoch-Schönlein purpura nephritis. Pediatr Nephrol (2014) 0.86
Antigen binding to secretory immunoglobulin A results in decreased sensitivity to intestinal proteases and increased binding to cellular Fc receptors. J Biol Chem (2009) 0.86
Differential binding characteristics of native monomeric and polymeric immunoglobulin A1 (IgA1) on human mesangial cells and the influence of in vitro deglycosylation of IgA1 molecules. Clin Exp Immunol (2007) 0.85
IL5RA and TNFRSF6B gene variants are associated with sporadic IgA nephropathy. J Am Soc Nephrol (2008) 0.85
Dysfunctions of the Iga system: a common link between intestinal and renal diseases. Cell Mol Immunol (2011) 0.84
MPO-ANCA-positive IgA nephropathy successfully treated with tonsillectomy. Clin Exp Nephrol (2007) 0.83
Tissue deposits of IgA-binding streptococcal M proteins in IgA nephropathy and Henoch-Schonlein purpura. Am J Pathol (2010) 0.83
Antibodies and their receptors: different potential roles in mucosal defense. Front Immunol (2013) 0.82
The role of Fc receptors in HIV prevention and therapy. Immunol Rev (2015) 0.81
The unexplored roles of human serum IgA. DNA Cell Biol (2014) 0.81
IgA and IgA-specific receptors in human disease: structural and functional insights into pathogenesis and therapeutic potential. Springer Semin Immunopathol (2006) 0.81
Immunoglobulin A: A next generation of therapeutic antibodies? MAbs (2011) 0.81
Suppression of adiponectin by aberrantly glycosylated IgA1 in glomerular mesangial cells in vitro and in vivo. PLoS One (2012) 0.79
Rare Variants in the Complement Factor H-Related Protein 5 Gene Contribute to Genetic Susceptibility to IgA Nephropathy. J Am Soc Nephrol (2016) 0.78
In vitro-generated immune complexes containing galactose-deficient IgA1 stimulate proliferation of mesangial cells. Results Immunol (2012) 0.78
siRNA delivery to the glomerular mesangium using polycationic cyclodextrin nanoparticles containing siRNA. Nucleic Acid Ther (2015) 0.78
IgA1 Protease Treatment Reverses Mesangial Deposits and Hematuria in a Model of IgA Nephropathy. J Am Soc Nephrol (2016) 0.77
Differential expression of functional Fc-receptors and additional immune complex receptors on mouse kidney cells. Mol Immunol (2013) 0.77
Update on immunoglobulin A nephropathy, Part I: Pathophysiology. World J Nephrol (2015) 0.76
Development of Animal Models of Human IgA Nephropathy. Drug Discov Today Dis Models (2014) 0.76
Rotavirus specific plasma secretory immunoglobulin in children with acute gastroenteritis and children vaccinated with an attenuated human rotavirus vaccine. Hum Vaccin Immunother (2013) 0.76
Erythropoiesis lagging? pIgA1 steps in to assist Epo. Nat Med (2011) 0.75
Why, when and how should immunosuppressive therapy considered in patients with immunoglobulin A nephropathy? Clin Exp Immunol (2016) 0.75
Inflammation in IgA nephropathy. Pediatr Nephrol (2017) 0.75
Maternal Immunization: New Perspectives on Its Application Against Non-Infectious Related Diseases in Newborns. Vaccines (Basel) (2017) 0.75
Transcriptomic and Proteomic Profiling Provides Insight into Mesangial Cell Function in IgA Nephropathy. J Am Soc Nephrol (2017) 0.75
New procedure for DNA transfection with polycation and dimethyl sulfoxide. Mol Cell Biol (1984) 8.63
Primary structure of human transferrin receptor deduced from the mRNA sequence. Nature (1984) 4.04
The receptor for transepithelial transport of IgA and IgM contains multiple immunoglobulin-like domains. Nature (1984) 3.33
Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor. Cell (1998) 2.80
Circulating immune complexes in IgA nephropathy consist of IgA1 with galactose-deficient hinge region and antiglycan antibodies. J Clin Invest (1999) 2.77
Fc alpha/mu receptor mediates endocytosis of IgM-coated microbes. Nat Immunol (2000) 2.66
The structure and function of human IgA. Biochem J (1990) 2.65
Secretory component of epithelial cells is a surface receptor for polymeric immunoglobulins. J Exp Med (1978) 2.26
Selective deposition of immunoglobulin A1 in immunoglobulin A nephropathy, anaphylactoid purpura nephritis, and systemic lupus erythematosus. J Clin Invest (1980) 2.11
Structural requirements for basolateral sorting of the human transferrin receptor in the biosynthetic and endocytic pathways of Madin-Darby canine kidney cells. J Cell Biol (1997) 1.78
Sorting signals in the MHC class II invariant chain cytoplasmic tail and transmembrane region determine trafficking to an endocytic processing compartment. J Cell Biol (1994) 1.73
Cellular distribution, regulation, and biochemical nature of an Fc alpha receptor in humans. J Exp Med (1990) 1.60
Expression cloning of a human Fc receptor for IgA. J Exp Med (1990) 1.59
Charge and size of mesangial IgA in IgA nephropathy. Kidney Int (1985) 1.34
IgA interaction with the asialoglycoprotein receptor. Proc Natl Acad Sci U S A (1982) 1.29
Soluble IgA and IgG aggregates are catabolized by cultured rat mesangial cells and induce production of TNF-alpha and IL-6, and proliferation. J Immunol (1994) 1.23
Molecular heterogeneity of Fc alpha receptors detected by receptor-specific monoclonal antibodies. J Immunol (1992) 1.20
Immunofluorescence analysis of IgA binding by human mononuclear cells in blood and lymphoid tissue. J Immunol (1989) 1.13
Lack of association of secretory component with IgA in J chain-deficient mice. J Immunol (1996) 1.13
Definition of immunoglobulin A receptors on eosinophils and their enhanced expression in allergic individuals. J Clin Invest (1993) 1.07
My 43, a monoclonal antibody that reacts with human myeloid cells inhibits monocyte IgA binding and triggers function. J Immunol (1989) 1.07
The N-glycans determine the differential blood clearance and hepatic uptake of human immunoglobulin (Ig)A1 and IgA2 isotypes. J Exp Med (2000) 1.06
Absence of CD89, polymeric immunoglobulin receptor, and asialoglycoprotein receptor on human mesangial cells. J Am Soc Nephrol (2000) 1.02
Colostral neutrophils express Fc alpha receptors (CD89) lacking gamma chain association and mediate noninflammatory properties of secretory IgA. J Leukoc Biol (2001) 1.01
Evidence for a specific IgA receptor in rat and human mesangial cells. J Immunol (1993) 1.00
A subset of human dendritic cells expresses IgA Fc receptor (CD89), which mediates internalization and activation upon cross-linking by IgA complexes. J Immunol (2001) 0.98
Evaluation of monoclonal antibodies with specificity for human IgA, IgA subclasses and allotypes and secretory component. Results of an IUIS/WHO collaborative study. J Immunol Methods (1996) 0.96
Expression of receptors for IgA on mitogen-stimulated human T lymphocytes. Eur J Immunol (1988) 0.96
Vectors and genes for improvement of animal strains. J Reprod Fertil Suppl (1990) 0.93
Prostaglandin synthesis by human glomerular cells in culture. Prostaglandins (1983) 0.91
Elevation of serum IgA in spondyloarthropathies and IgA nephropathy and its pathogenic role. Curr Opin Rheumatol (1999) 0.91
Mucosal immunoglobulins and their contribution to defence mechanisms: an overview. Biochem Soc Trans (1997) 0.91
IgA induced activation of human mesangial cells: independent of FcalphaR1 (CD 89). Kidney Int (1998) 0.91
Human mesangial cells in culture and in kidney sections fail to express Fc alpha receptor (CD89). J Am Soc Nephrol (1999) 0.84
Identification of a novel Fcalpha receptor expressed by human mesangial cells. Kidney Int (2000) 0.83
The cDNA sequence and primary structure of the chicken transferrin receptor. Gene (1991) 0.82
Human intestinal epithelial cells express a novel receptor for IgA. J Immunol (2000) 0.79
Spontaneous expression of a low affinity Fc receptor for IgA (Fc alpha R) on human B cell lines. Clin Exp Immunol (1989) 0.79
Functional analysis of two human T-cell subpopulations: help and suppression of B-cell responses by T cells bearing receptors for IgM or IgG. J Exp Med (1977) 9.57
Signal-dependent membrane protein trafficking in the endocytic pathway. Annu Rev Cell Biol (1993) 7.16
The T cell dependence of B cell differentiation induced by pokeweed mitogen. J Immunol (1976) 4.40
The functions of the thymus system and the bursa system in the chicken. J Exp Med (1966) 4.07
Immunofluorescent studies of the development of pre-B cells, B lymphocytes and immunoglobulin isotype diversity in humans. Eur J Immunol (1977) 4.00
The IgA system. I. Studies of the transport and immunochemistry of IgA in the saliva. J Exp Med (1966) 3.97
Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen. J Exp Med (1999) 3.78
Wiskott-Aldrich syndrome. An immunologic deficiency disease involving the afferent limb of immunity. Am J Med (1968) 3.54
Pinocytosis by epithelium associated with lymphoid follicles in the bursa of Fabricius, appendix, and Peyer's patches. An electron microscopic study. Am J Anat (1973) 3.38
Suppression of immunoglobulin class synthesis in mice. I. Effects of treatment with antibody to -chain. J Exp Med (1972) 3.32
Early production of intracellular IgM by B-lymphocyte precursors in mouse. Nature (1976) 3.29
A map of local adaptation in Arabidopsis thaliana. Science (2011) 3.27
Human T lymphocyte subpopulations defined by Fc receptors and monoclonal antibodies. A comparison. J Exp Med (1980) 3.03
Suppression of immunoglobulin G synthesis as a result of antibody-mediated suppression of immunoglobulin M synthesis in chickens. Proc Natl Acad Sci U S A (1970) 2.93
Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes. J Exp Med (1998) 2.75
Differentiation capacity of cultured B lymphocytes from immunodeficient patients. J Clin Invest (1973) 2.65
Characterization of HNK-1+ (Leu-7) human lymphocytes. I. Two distinct phenotypes of human NK cells with different cytotoxic capability. J Immunol (1982) 2.63
Morphological and histochemical analyses of two human T-cell subpopulations bearing receptors for IgM or IgG. J Exp Med (1978) 2.58
Agammaglobulinaemia with B lymphocytes. Specific defect of plasma-cell differentiation. Lancet (1971) 2.55
Mouse pre-B cells synthesize and secrete mu heavy chains but not light chains. Cell (1980) 2.50
Development and distribution of immunoglobulin-containing cells in the chicken. An immunofluorescent analysis using purified antibodies to mu, gamma and light chains. J Immunol (1971) 2.46
A monoclonal antibody (MMA) that identifies a differentiation antigen on human myelomonocytic cells. Clin Immunol Immunopathol (1982) 2.41
Immunologic abnormalities in pathogen-free cats experimentally infected with feline immunodeficiency virus. J Virol (1990) 2.40
Differences in susceptibility of mature and immature mouse B lymphocytes to anti-immunoglobulin-induced immunoglobulin suppression in vitro. Possible implications for B-cell tolerance to self. J Exp Med (1975) 2.40
Postnatal expansion of the natural killer and keller cell population in humans identified by the monoclonal HNK-1 antibody. J Exp Med (1982) 2.35
Differential activation requirements for virgin and memory T cells. J Immunol (1988) 2.34
A mammalian equivalent of the avian bursa of Fabricius. Lancet (1966) 2.11
Selective deposition of immunoglobulin A1 in immunoglobulin A nephropathy, anaphylactoid purpura nephritis, and systemic lupus erythematosus. J Clin Invest (1980) 2.11
A novel pair of immunoglobulin-like receptors expressed by B cells and myeloid cells. Proc Natl Acad Sci U S A (1997) 2.11
Circulating B-cells in patients with immunodeficiency. Am J Pathol (1972) 2.07
Expression of C3d receptors during human B cell differentiation: immunofluorescence analysis with the HB-5 monoclonal antibody. J Immunol (1984) 2.06
Development and function of the immunoglobulin producing system. I. Effect of bursectomy at different stages of development on germinal centers, plasma cells, immunoglobulins and antibody production. Int Arch Allergy Appl Immunol (1969) 2.06
In vitro generation of B lymphocytes in mouse foetal liver, a mammalian 'bursa equivalent'. Nature (1974) 2.05
Pre-B-cell leukemia. A new phenotype of childhood lymphoblastic leukemia. N Engl J Med (1978) 2.05
Behavior of glycopolypeptides with empirical molecular weight estimation methods. 1. In sodium dodecyl sulfate. Biochemistry (1980) 2.03
Identification of the TCL1 gene involved in T-cell malignancies. Proc Natl Acad Sci U S A (1994) 2.02
Restriction of surface immunoglobulin determinants to lymphocytes of the plasma cell line. J Immunol (1971) 2.01
Sequential expression of immunoglobulin on developing mouse B lymphocytes: a systematic survey that suggests a model for the generation of immunoglobulin isotype diversity. J Immunol (1978) 1.99
Tissue localization and CD8 accessory molecule expression of T gamma delta cells in humans. J Immunol (1989) 1.96
T cells can bind antigen via cytophilic IgM antibody made by B cells. J Immunol (1973) 1.95
Human B cell differentiation. II. Pokeweed mitogen-responsive B cells belong to a surface immunoglobulin D-negative subpopulation. J Exp Med (1982) 1.92
Human lymphocyte differentiation antigens HB-10 and HB-11. II. Differential production of B cell growth and differentiation factors by distinct helper T cell subpopulations. J Immunol (1985) 1.91
Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors. J Biol Chem (1993) 1.88
B lymphocyte precursors in human bone marrow: an analysis of normal individuals and patients with antibody-deficiency states. J Immunol (1978) 1.88
Identification of a family of Fc receptor homologs with preferential B cell expression. Proc Natl Acad Sci U S A (2001) 1.84
Human T lymphocyte subpopulations: studies of the mechanism by which T cells bearing Fc receptors for IgG suppress T-dependent B cell differentiation induced by pokeweed mitogen. J Immunol (1979) 1.80
Role of the thymus and other central lymphoid tissues in immunological disease. Annu Rev Med (1967) 1.76
Acquired immune dysfunction in cats with experimentally induced feline immunodeficiency virus infection: comparison of short-term and long-term infections. J Acquir Immune Defic Syndr (1991) 1.75
The primary immunodeficiencies (1). N Engl J Med (1984) 1.74
Imbalances in T cell subpopulations associated with immunodeficiency and autoimmune syndromes. Eur J Immunol (1977) 1.74
Sorting signals in the MHC class II invariant chain cytoplasmic tail and transmembrane region determine trafficking to an endocytic processing compartment. J Cell Biol (1994) 1.73
Studies on the clonal origin of multiple myeloma. Use of individually specific (idiotype) antibodies to trace the oncogenic event to its earliest point of expression in B-cell differentiation. J Exp Med (1979) 1.70
Evidence for an IgD homologue on chicken lymphocytes. J Immunol (1982) 1.70
Avian T cells expressing gamma delta receptors localize in the splenic sinusoids and the intestinal epithelium. J Immunol (1988) 1.70
A large subpopulation of avian T cells express a homologue of the mammalian T gamma/delta receptor. J Exp Med (1988) 1.70
Lymphoid tissue abnormalities associated with ataxia-telangiectasia. Am J Med (1966) 1.69
Modification of B lymphocyte differentiation by anti-immunoglobulins. Contemp Top Immunobiol (1974) 1.66
The primary immunodeficiencies. N Engl J Med (1995) 1.65
Ontogeny of B cells in the chicken. I. Sequential development of clonal diversity in the bursa. J Exp Med (1976) 1.63
IgG subclass expression by human B lymphocytes and plasma cells: B lymphocytes precommitted to IgG subclass can be preferentially induced by polyclonal mitogens with T cell help. J Immunol (1983) 1.61
Cellular distribution, regulation, and biochemical nature of an Fc alpha receptor in humans. J Exp Med (1990) 1.60
Mu heavy chains can associate with a pseudo-light chain complex (psi L) in human pre-B cell lines. Int Immunol (1989) 1.59
Pathogenesis of IgA1 protease-producing and -nonproducing Haemophilus influenzae in human nasopharyngeal organ cultures. J Infect Dis (1986) 1.58
Mutations in the human lambda5/14.1 gene result in B cell deficiency and agammaglobulinemia. J Exp Med (1998) 1.55
A novel cell surface molecule on early B-lineage cells. Nature (1986) 1.55
Molecular cloning of the murine BP-1/6C3 antigen: a member of the zinc-dependent metallopeptidase family. Proc Natl Acad Sci U S A (1990) 1.54
Pathogenesis of avian lymphoid leukosis. I. Histogenesis. J Natl Cancer Inst (1968) 1.54
Ontogeny of circulating immunoglobulin in normal, bursectomized and irradiated chickens. J Immunol (1969) 1.54
Impairment of T and B cell development by treatment with a type I interferon. J Exp Med (1998) 1.54
T cell receptor gene deletion circles identify recent thymic emigrants in the peripheral T cell pool. Proc Natl Acad Sci U S A (1999) 1.54
A two-stage model for development of antibody-producing cells. Clin Exp Immunol (1972) 1.53
Identification of the avian homologues of mammalian CD4 and CD8 antigens. J Immunol (1988) 1.52
A feline thymocyte antigen defined by a monoclonal antibody (FT2) identifies a subpopulation of non-helper cells capable of specific cytotoxicity. J Immunol (1986) 1.52
Two new acute lymphoblastic leukemia cell lines with early B-cell phenotypes. Blood (1982) 1.52
Pre-B cells: bone marrow persistence in anti-mu-suppressed mice, conversion to B lymphocytes, and recovery after destruction by cyclophosphamide. J Immunol (1978) 1.51
Identification of a CD4 homologue in the cat. Tissue Antigens (1990) 1.51
Studies on the generation of B lymphocytes in the mouse embryo. Eur J Immunol (1976) 1.51
Abnormalities of T cell maturation and regulation in human beings with immunodeficiency disorders. J Clin Invest (1981) 1.50
Memory B lymphocytes migrate to bone marrow in humans. Proc Natl Acad Sci U S A (1997) 1.50
Thymic function can be accurately monitored by the level of recent T cell emigrants in the circulation. Immunity (1998) 1.49
Rosette formation with mouse erythrocytes defines a population of human B lymphocytes unresponsive to pokeweed mitogen. Clin Exp Immunol (1981) 1.48
B cells are generated throughout life in humans. J Immunol (1996) 1.47
B lymphocyte differentiation induced by lipopolysaccharide. III. Suppression of B cell maturation by anti-mouse immunoglobulin antibodies. J Immunol (1976) 1.47
Identification of a T3/T cell receptor complex in chickens. J Exp Med (1986) 1.46
Differential expression of two T cell receptors, TcR1 and TcR2, on chicken lymphocytes. Eur J Immunol (1988) 1.46
Biochemical nature and cellular distribution of the paired immunoglobulin-like receptors, PIR-A and PIR-B. J Exp Med (1999) 1.44
Ontogeny of Ia and IgD on IgM-bearing B lymphocytes in mice. J Exp Med (1977) 1.44
The primary immunodeficiencies. (2). N Engl J Med (1984) 1.43
Characterization of human T-cell subpopulations as defined by specific receptors for immunoglobulins. Contemp Top Immunobiol (1978) 1.42
Activation of human B cells and inhibition of their terminal differentiation by monoclonal anti-mu antibodies. J Immunol (1985) 1.40
Generation of immunoglobulin class diversity in b cells: a discussion with emphasis on idg development. Ann Immunol (Paris) (1976) 1.40
Radiometric estimation of the replication time of bacteria in culture: an objective and precise approach to quantitative microbiology. J Nucl Med (1978) 1.40
Basal ganglia regional glucose metabolism asymmetry during a catatonic episode. Biol Psychiatry (1989) 1.38
Studies on the nature of the abnormality of B cell differentiation in avian lymphoid leukosis: production of heterogeneous IgM by tumor cells. J Immunol (1974) 1.37
Syntaxin 1A inhibits CFTR chloride channels by means of domain-specific protein-protein interactions. Proc Natl Acad Sci U S A (1998) 1.35
Efficient endocytosis of the cystic fibrosis transmembrane conductance regulator requires a tyrosine-based signal. J Biol Chem (1999) 1.35
gamma/delta T cell-deficient mice have impaired mucosal immunoglobulin A responses. J Exp Med (1996) 1.35
Charge and size of mesangial IgA in IgA nephropathy. Kidney Int (1985) 1.34
Human IL-7: a novel T cell growth factor. J Immunol (1989) 1.34