Published in Blood on September 15, 2001
A 76-kb duplicon maps close to the BCR gene on chromosome 22 and the ABL gene on chromosome 9: possible involvement in the genesis of the Philadelphia chromosome translocation. Proc Natl Acad Sci U S A (2002) 1.25
Chronic myeloid leukemia treatment guidelines: Brazilian Association of Hematology, Hemotherapy and Cell Therapy. Brazilian Medical Association Guidelines Project - 2012. Rev Bras Hematol Hemoter (2012) 1.22
Non random distribution of genomic features in breakpoint regions involved in chronic myeloid leukemia cases with variant t(9;22) or additional chromosomal rearrangements. Mol Cancer (2010) 0.97
FISH mapping of Philadelphia negative BCR/ABL1 positive CML. Mol Cytogenet (2008) 0.94
Reciprocal t(9;22) ABL/BCR fusion proteins: leukemogenic potential and effects on B cell commitment. PLoS One (2009) 0.90
Gene expression profiling of chronic myeloid leukemia with variant t(9;22) reveals a different signature from cases with classic translocation. Mol Cancer (2013) 0.89
Large scale copy number variation (CNV) at 14q12 is associated with the presence of genomic abnormalities in neoplasia. BMC Genomics (2006) 0.89
ABL-BCR expression does not correlate with deletions on the derivative chromosome 9 or survival in chronic myeloid leukemia. Blood (2001) 0.83
An approach to the management of chronic myeloid leukemia in British Columbia. Curr Oncol (2008) 0.82
On the Power of Additional and Complex Chromosomal Aberrations in CML. Curr Genomics (2012) 0.81
Targeted treatment of chronic myeloid leukemia: role of imatinib. Onco Targets Ther (2009) 0.78
Derivative chromosome 9 deletions in chronic myeloid leukaemia: interpretation of atypical D-FISH pattern. J Clin Pathol (2003) 0.75
Application of tri-colour, dual fusion fluorescence in situ hybridization (FISH) system for the characterization of BCR-ABL1 fusion in chronic myelogenous leukaemia (CML) and residual disease monitoring. BMC Blood Disord (2009) 0.75
Molecular techniques for the personalised management of patients with chronic myeloid leukaemia. Biomol Detect Quantif (2017) 0.75
[Current diagnostic requirements in chronic myeloid leukemia]. Wien Med Wochenschr (2013) 0.75
Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2. N Engl J Med (2013) 8.89
Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts. N Engl J Med (2011) 7.89
Effects of atropine on heart-rate in healthy man. Lancet (1967) 5.10
Cross-cultural primary care: a patient-based approach. Ann Intern Med (1999) 5.06
Effect of homeopathic treatment on fibrositis (primary fibromyalgia) BMJ (1989) 5.00
Guidelines for the use of antifungal agents in the treatment of invasive Candida and mould infections. Intern Med J (2004) 4.70
Rapid method for the determination of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in small regions of rat brain. Br J Pharmacol (1970) 4.48
Localization of the human alpha-globin structural gene to chromosome 16 in somatic cell hybrids by molecular hybridization assay. Cell (1977) 4.34
Analysis of vertebrate SCL loci identifies conserved enhancers. Nat Biotechnol (2000) 4.01
The effects of a new beta-adrenoceptive receptor blocking drug on heart rate in man. Br J Pharmacol Chemother (1968) 3.95
Effect of peripheral-blood progenitor cells mobilised by filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy. Lancet (1992) 3.76
Mucosal adherence of human enteropathogenic Escherichia coli. Lancet (1975) 3.54
The effect of propranolol on anxiety. Lancet (1966) 3.33
The Radical Cure of Inguinal Hernia in Children. Proc R Soc Med (1912) 3.29
Preliminary investigations of a new beta-adrenoceptive receptor blocking drug, LB46, in man. Br J Pharmacol (1969) 3.25
A gene-expression signature to predict survival in breast cancer across independent data sets. Oncogene (2006) 3.21
Ecstasy and neurodegeneration. BMJ (1996) 2.93
Linkage of the angiotensinogen gene to essential hypertension. N Engl J Med (1994) 2.80
Differences in human alpha-, beta- and delta-globin gene expression in monkey kidney cells. Cell (1982) 2.78
Total synthesis of a human leukocyte interferon gene. Nature (1981) 2.76
Chromosomal localization of human beta globin gene on human chromosome 11 in somatic cell hybrids. Proc Natl Acad Sci U S A (1978) 2.65
How to improve plastic surgery knowledge, skills and career interest in undergraduates in one day. J Plast Reconstr Aesthet Surg (2009) 2.54
Mechanism of action of immunomodulatory drugs (IMiDS) in multiple myeloma. Leukemia (2009) 2.50
Sensitive method for the routine determination tricyclic antidepressants in plasma using a specific nitrogen detector. J Chromatogr (1975) 2.48
The SCL gene specifies haemangioblast development from early mesoderm. EMBO J (1998) 2.47
Recombinant activated factor VII in treatment of bleeding complications following hematopoietic stem cell transplantation. J Thromb Haemost (2005) 2.46
Studies of the interaction of desmethylimipramine with tyramine in man after a single oral dose, and its correlation with plasma concentration. Br J Clin Pharmacol (1976) 2.29
The socioemotional development of 5-year-old children of postnatally depressed mothers. J Child Psychol Psychiatry (1999) 2.23
Plasma concentrations of fenfluramine and its metabolite, norfenfluramine, after single and repeated oral administration. Br J Pharmacol (1971) 2.23
The severity of asthma in relation to beta agonist prescribing. N Z Med J (1991) 2.20
Talking about drugs - the role of the clinical pharmacologist. J R Soc Med (1982) 2.15
Cardiac and pulmonary effects of acebutolol. Lancet (1975) 2.12
The interactions of local guanethidine and sympathomimetic amines in the human eye. Arch Ophthalmol (1969) 2.09
Effect of adrenergic receptor blockade of the tachycardia of thyrotoxicosis and anxiety state. Lancet (1965) 2.09
African trypanosomiasis in two travelers from the United States. Clin Infect Dis (1999) 2.08
Critical flicker frequency and centrally-acting drugs. Br J Ophthalmol (1968) 2.08
A simple method to measure drug effects on human sperm motility. Br J Clin Pharmacol (1981) 2.06
A randomized study of high-dose cytarabine in induction in acute myeloid leukemia. Blood (1996) 2.06
Exercise increases muscle GLUT-4 levels and insulin action in subjects with impaired glucose tolerance. Am J Physiol (1993) 2.06
Molecular characteristics and prognostic features of breast cancer in Nigerian compared with UK women. Breast Cancer Res Treat (2012) 2.05
An investigation into the cardiac and pulmonary beta-adrenoceptor blocking activity of ICI 66,082 in man. Br J Clin Pharmacol (1975) 2.05
The mechanism of adenosine diphosphate induced platelet aggregation: binding to platelet receptors and inhibition of binding and aggregation by prostaglandin E 1 . J Physiol (1972) 2.05
Long-range comparison of human and mouse SCL loci: localized regions of sensitivity to restriction endonucleases correspond precisely with peaks of conserved noncoding sequences. Genome Res (2001) 2.04
Mechanism of the antidepressant action of electroconvulsive therapy. Lancet (1978) 2.03
Adrenergic blockade and the eye signs of thyrotoxicosis. Lancet (1966) 2.02
BCL2 in breast cancer: a favourable prognostic marker across molecular subtypes and independent of adjuvant therapy received. Br J Cancer (2010) 1.99
Relative potencies of sympathetic amines in human smooth muscle. Br J Pharmacol (1969) 1.98
Intravenous tyramine pressor response in depression. Lancet (1975) 1.98
Morphological and immunophenotypic analysis of breast carcinomas with basal and myoepithelial differentiation. J Pathol (2006) 1.97
Guidelines for the diagnosis, investigation and management of polycythaemia/erythrocytosis. Br J Haematol (2005) 1.96
Some central and peripheral effects of meclastine, a new antihistaminic drug, in man. J Clin Pharmacol New Drugs (1971) 1.94
Action of fenfluramine on isolated human smooth muscle. Lancet (1969) 1.94
The inhibitory action of procaine, (+)-propranolol and (+/-)-propranolol on human sperm motility: antagonism by caffeine. Br J Clin Pharmacol (1981) 1.88
Written information given to patients and families by palliative care units: a national survey. Lancet (2000) 1.88
Some clinical pharmacological studies with terfenadine, a new antihistamine drug. Br J Clin Pharmacol (1978) 1.86
The bioavailability of quinine. J Trop Med Hyg (1976) 1.80
Rituximab in the adjuvant treatment of pemphigus vulgaris: a prospective open-label pilot study in five patients. Br J Dermatol (2007) 1.80
Loss and representativeness in a biomedical survey at age 45 years: 1958 British birth cohort. J Epidemiol Community Health (2008) 1.80
Effects of drugs on the processes regulating the functional activity of brain 5-hydroxytryptamine. Nature (1976) 1.77
The prognostic significance of B lymphocytes in invasive carcinoma of the breast. Breast Cancer Res Treat (2011) 1.74
Treatment for acute myelocytic leukemia with allogeneic bone marrow transplantation following preparation with BuCy2. Blood (1991) 1.72
Class experiment in clinical pharmacology with benzilonium bromide, an anticholinergic drug. Eur J Clin Pharmacol (1974) 1.72
Analysis of pineal and brain indole alkylamines by gas chromatography-mass spectrometry. Adv Biochem Psychopharmacol (1973) 1.71
International trial of long-term dexfenfluramine in obesity. Lancet (1989) 1.70
A comparison of the effects of chlorphentermine, diethylpropion and phenmetrazine on critical flicker frequency. Br J Pharmacol Chemother (1967) 1.70
Inadequacy of iridium implant as sole radiation treatment for operable breast cancer. Eur J Cancer (1996) 1.70
Decrease of 5-hydroxytryptamine in the brain provoked by hydrocortisone and its prevention by allopurinol. Nature (1968) 1.69
Prescription of benzodiazepines in a London teaching hospital. J R Soc Med (1990) 1.69
Autonomic actions and interactions of mianserin hydrochloride (Org. GB 94) and amitriptyline in patients with depressive illness. Psychopharmacology (Berl) (1976) 1.68
hOCT1 transcript levels and single nucleotide polymorphisms as predictive factors for response to imatinib in chronic myeloid leukemia. Leukemia (2010) 1.67
An SCL 3' enhancer targets developing endothelium together with embryonic and adult haematopoietic progenitors. Development (1999) 1.67
The SCL gene: from case report to critical hematopoietic regulator. Blood (1999) 1.65
Active conformation of the globin genes in uninduced and induced mouse erythroleukemia cells. Cell (1978) 1.64
Prospective randomised trial of amifostine cytoprotection in myeloma patients undergoing high-dose melphalan conditioned autologous stem cell transplantation. Bone Marrow Transplant (2005) 1.64
The BH3 mimetic compound, ABT-737, synergizes with a range of cytotoxic chemotherapy agents in chronic lymphocytic leukemia. Leukemia (2009) 1.63
Variable carbohydrate modifications to the catalytic chains of the RgpA and RgpB proteases of Porphyromonas gingivalis W50. Infect Immun (1999) 1.61
Alpha receptor blockade by thymoxamine in the human eye. Clin Pharmacol Ther (1968) 1.60
Effects of NXY-059 in experimental stroke: an individual animal meta-analysis. Br J Pharmacol (2009) 1.60
Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member. Biochem Biophys Res Commun (2000) 1.59
Large deletions at the t(9;22) breakpoint are common and may identify a poor-prognosis subgroup of patients with chronic myeloid leukemia. Blood (2000) 1.58
Breast carcinoma with basal differentiation: a proposal for pathology definition based on basal cytokeratin expression. Histopathology (2007) 1.57
Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56
Cephalosporin-induced immune neutropenia. Br J Haematol (1985) 1.56
Absorption of propranolol and practolol in Coeliac disease. Gut (1976) 1.55
Caveolin 1 and Caveolin 2 are associated with breast cancer basal-like and triple-negative immunophenotype. Br J Cancer (2008) 1.55
Neurological events associated with the infusion of cryopreserved bone marrow and/or peripheral blood progenitor cells. Bone Marrow Transplant (2000) 1.54
Introduction to the updated Australian and New Zealand consensus guidelines for the use of antifungal agents in the haematology/oncology setting, 2014. Intern Med J (2014) 1.54
Bile duct injury during laparoscopic cholecystectomy: a report of the Standards Sub-committee of the Victorian State Committee of the Royal Australasian College of Surgeons. Aust N Z J Surg (1993) 1.53
The Treatment of a Denture, Swallowed and Impacted in the OEsophagus, by means of Killian's OEsophageal Tube. Proc R Soc Med (1909) 1.51
Short-term primary culture of epithelial cells derived from human breast tumours. Br J Cancer (1998) 1.51
Electroconvulsive shock increases the behavioural responses of rats to brain 5-hydroxytryptamine accumulation and central nervous system stimulant drugs. Br J Pharmacol (1976) 1.48
The effects of putative 5-hydroxytryptamine antagonists on the behaviour produced by administration of tranylcypromine and L-tryptophan or tranylcypromine and L-DOPA to rats. Br J Pharmacol (1978) 1.48
Explanation for potency of repeated oral doses of morphine? Lancet (1987) 1.47
Proceedings: Effect of fenfluramine and norfenfluramine on glucose uptake by the isolated rat diaphragm. Br J Pharmacol (1974) 1.46
Environmental impacts and sustainability of egg production systems. Poult Sci (2011) 1.46
A comparison of the effects of propranolol and practolol on forced expiratory volume and resting heart rate in normal subjects. Arch Int Pharmacodyn Ther (1971) 1.45
Intravenous treatment with rimiterol and salbutamol in asthma. Br Med J (1975) 1.45