Anthrax.

Furin at the cutting edge: from protein traffic to embryogenesis and disease. Nat Rev Mol Cell Biol (2002) 6.37

Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor. Proc Natl Acad Sci U S A (2003) 5.95

Sortases and the art of anchoring proteins to the envelopes of gram-positive bacteria. Microbiol Mol Biol Rev (2006) 4.88

Population structure and evolution of the Bacillus cereus group. J Bacteriol (2004) 3.08

Identification of the immunodominant protein and other proteins of the Bacillus anthracis exosporium. J Bacteriol (2003) 2.48

Routine markerless gene replacement in Bacillus anthracis. Infect Immun (2006) 2.42

Diversity among French Bacillus anthracis isolates. J Clin Microbiol (2002) 2.41

Murine model of pulmonary anthrax: kinetics of dissemination, histopathology, and mouse strain susceptibility. Infect Immun (2004) 2.14

An overview of anthrax infection including the recently identified form of disease in injection drug users. Intensive Care Med (2012) 2.10

Polymorphism in the collagen-like region of the Bacillus anthracis BclA protein leads to variation in exosporium filament length. J Bacteriol (2003) 1.99

Roles of macrophages and neutrophils in the early host response to Bacillus anthracis spores in a mouse model of infection. Infect Immun (2006) 1.93

Role of pore-forming toxins in bacterial infectious diseases. Microbiol Mol Biol Rev (2013) 1.91

Cytokine response to infection with Bacillus anthracis spores. Infect Immun (2004) 1.86

Sensor complexes regulating two-component signal transduction. Curr Opin Struct Biol (2007) 1.82

Anthrax lethal toxin induces endothelial barrier dysfunction. Am J Pathol (2005) 1.81

Characterization of anthrolysin O, the Bacillus anthracis cholesterol-dependent cytolysin. Infect Immun (2003) 1.81

Bacillus thuringiensis: a genomics and proteomics perspective. Bioeng Bugs (2011) 1.77

The secret life of the anthrax agent Bacillus anthracis: bacteriophage-mediated ecological adaptations. PLoS One (2009) 1.73

Primary involvement of pharynx and peyer's patch in inhalational and intestinal anthrax. PLoS Pathog (2007) 1.70

Complete sequence analysis of novel plasmids from emetic and periodontal Bacillus cereus isolates reveals a common evolutionary history among the B. cereus-group plasmids, including Bacillus anthracis pXO1. J Bacteriol (2006) 1.70

Functional analysis of Bacillus anthracis protective antigen by using neutralizing monoclonal antibodies. Infect Immun (2004) 1.64

Bacillus anthracis produces membrane-derived vesicles containing biologically active toxins. Proc Natl Acad Sci U S A (2010) 1.62

Retrograde transport pathways utilised by viruses and protein toxins. Virol J (2006) 1.61

A high-affinity monoclonal antibody to anthrax protective antigen passively protects rabbits before and after aerosolized Bacillus anthracis spore challenge. Infect Immun (2005) 1.61

Norepinephrine increases blood pressure but not survival with anthrax lethal toxin in rats. Crit Care Med (2009) 1.60

Mapping dominant-negative mutations of anthrax protective antigen by scanning mutagenesis. Proc Natl Acad Sci U S A (2003) 1.59

The intestinal life cycle of Bacillus subtilis and close relatives. J Bacteriol (2006) 1.55

A dually active anthrax vaccine that confers protection against both bacilli and toxins. Proc Natl Acad Sci U S A (2003) 1.54

A novel FtsZ-like protein is involved in replication of the anthrax toxin-encoding pXO1 plasmid in Bacillus anthracis. J Bacteriol (2006) 1.54

Characterization of the exosporium basal layer protein BxpB of Bacillus anthracis. J Bacteriol (2005) 1.52

atxA controls Bacillus anthracis capsule synthesis via acpA and a newly discovered regulator, acpB. J Bacteriol (2004) 1.52

Role of luxS in Bacillus anthracis growth and virulence factor expression. Virulence (2010) 1.52

Capsules, toxins and AtxA as virulence factors of emerging Bacillus cereus biovar anthracis. PLoS Negl Trop Dis (2015) 1.51

Bacillus anthracis-derived nitric oxide is essential for pathogen virulence and survival in macrophages. Proc Natl Acad Sci U S A (2008) 1.49

Enhancement of anthrax lethal toxin cytotoxicity: a subset of monoclonal antibodies against protective antigen increases lethal toxin-mediated killing of murine macrophages. Infect Immun (2004) 1.47

Bacillus anthracis secretes proteins that mediate heme acquisition from hemoglobin. PLoS Pathog (2008) 1.47

Detailed genomic analysis of the Wbeta and gamma phages infecting Bacillus anthracis: implications for evolution of environmental fitness and antibiotic resistance. J Bacteriol (2006) 1.46

Bacillus anthracis sortase A (SrtA) anchors LPXTG motif-containing surface proteins to the cell wall envelope. J Bacteriol (2005) 1.46

Nucleation of platelets with blood-borne pathogens on Kupffer cells precedes other innate immunity and contributes to bacterial clearance. Nat Immunol (2013) 1.46

Selective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infection. Proc Natl Acad Sci U S A (2004) 1.46

The integrin Mac-1 (CR3) mediates internalization and directs Bacillus anthracis spores into professional phagocytes. Proc Natl Acad Sci U S A (2008) 1.44

Direct inhibition of T-lymphocyte activation by anthrax toxins in vivo. Infect Immun (2005) 1.43

Morphogenesis of the Bacillus anthracis spore. J Bacteriol (2006) 1.43

Beta-lactamase genes of the penicillin-susceptible Bacillus anthracis Sterne strain. J Bacteriol (2003) 1.42

Bacillus anthracis multiplication, persistence, and genetic exchange in the rhizosphere of grass plants. Appl Environ Microbiol (2006) 1.42

Cereulide synthetase gene cluster from emetic Bacillus cereus: structure and location on a mega virulence plasmid related to Bacillus anthracis toxin plasmid pXO1. BMC Microbiol (2006) 1.41

Human neutrophils kill Bacillus anthracis. PLoS Pathog (2005) 1.38

Genome-wide single nucleotide polymorphism typing method for identification of Bacillus anthracis species and strains among B. cereus group species. J Clin Microbiol (2010) 1.38

Single-copy chromosomal integration systems for Francisella tularensis. Microbiology (2009) 1.34

Population structure of the Bacillus cereus group as determined by sequence analysis of six housekeeping genes and the plcR Gene. Infect Immun (2004) 1.33

Distinct mutations in PlcR explain why some strains of the Bacillus cereus group are nonhemolytic. J Bacteriol (2004) 1.32

Murine aerosol challenge model of anthrax. Infect Immun (2007) 1.30

Anthrax toxins inhibit neutrophil signaling pathways in brain endothelium and contribute to the pathogenesis of meningitis. PLoS One (2008) 1.29

Proteomic profiling and identification of immunodominant spore antigens of Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis. Appl Environ Microbiol (2006) 1.29

Characterization of sporulation histidine kinases of Bacillus anthracis. J Bacteriol (2005) 1.28

Differential proteomic analysis of the Bacillus anthracis secretome: distinct plasmid and chromosome CO2-dependent cross talk mechanisms modulate extracellular proteolytic activities. J Bacteriol (2006) 1.28

Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins. EMBO J (2002) 1.28

Conjugative plasmid pAW63 brings new insights into the genesis of the Bacillus anthracis virulence plasmid pXO2 and of the Bacillus thuringiensis plasmid pBT9727. BMC Genomics (2005) 1.28

Identification of in vivo-expressed immunogenic proteins by serological proteome analysis of the Bacillus anthracis secretome. Infect Immun (2007) 1.28

Synthetic and crystallographic studies of a new inhibitor series targeting Bacillus anthracis dihydrofolate reductase. J Med Chem (2008) 1.26

Search for potential vaccine candidate open reading frames in the Bacillus anthracis virulence plasmid pXO1: in silico and in vitro screening. Infect Immun (2002) 1.26

The ExsY protein is required for complete formation of the exosporium of Bacillus anthracis. J Bacteriol (2006) 1.25

Rap phosphatase of virulence plasmid pXO1 inhibits Bacillus anthracis sporulation. J Bacteriol (2006) 1.23

ESAT-6-like protein secretion in Bacillus anthracis. J Bacteriol (2008) 1.23

Anthrax vaccine design: strategies to achieve comprehensive protection against spore, bacillus, and toxin. Med Immunol (2005) 1.22

MyD88-dependent signaling contributes to protection following Bacillus anthracis spore challenge of mice: implications for Toll-like receptor signaling. Infect Immun (2005) 1.22

Contributions of four cortex lytic enzymes to germination of Bacillus anthracis spores. J Bacteriol (2009) 1.22

Bacillus anthracis exosporium protein BclA affects spore germination, interaction with extracellular matrix proteins, and hydrophobicity. Infect Immun (2007) 1.22

Combining anthrax vaccine and therapy: a dominant-negative inhibitor of anthrax toxin is also a potent and safe immunogen for vaccines. Infect Immun (2005) 1.22

The InhA metalloproteases of Bacillus cereus contribute concomitantly to virulence. J Bacteriol (2010) 1.21

Bacillus anthracis surface-layer proteins assemble by binding to the secondary cell wall polysaccharide in a manner that requires csaB and tagO. J Mol Biol (2010) 1.21

Anthrax toxin protective antigen: inhibition of channel function by chloroquine and related compounds and study of binding kinetics using the current noise analysis. Biophys J (2004) 1.20

An anthrax lethal factor-neutralizing monoclonal antibody protects rats before and after challenge with anthrax toxin. Infect Immun (2005) 1.20

Immune defence, parasite evasion strategies and their relevance for 'macroscopic phenomena' such as virulence. Philos Trans R Soc Lond B Biol Sci (2009) 1.20

SporeWeb: an interactive journey through the complete sporulation cycle of Bacillus subtilis. Nucleic Acids Res (2013) 1.19

A peptide-based fluorescence resonance energy transfer assay for Bacillus anthracis lethal factor protease. Proc Natl Acad Sci U S A (2002) 1.18

Macrophages release tumor necrosis factor alpha and interleukin-12 in response to intracellular Bacillus anthracis spores. Infect Immun (2004) 1.18

Use of 16S rRNA, 23S rRNA, and gyrB gene sequence analysis to determine phylogenetic relationships of Bacillus cereus group microorganisms. J Clin Microbiol (2004) 1.18

Bacillus anthracis spores of the bclA mutant exhibit increased adherence to epithelial cells, fibroblasts, and endothelial cells but not to macrophages. Infect Immun (2007) 1.18

Complement depletion renders C57BL/6 mice sensitive to the Bacillus anthracis Sterne strain. Infect Immun (2005) 1.17

Characterization of genetic diversity of Bacillus anthracis in France by using high-resolution melting assays and multilocus variable-number tandem-repeat analysis. J Clin Microbiol (2011) 1.17

Noninvasive imaging technologies reveal edema toxin as a key virulence factor in anthrax. Am J Pathol (2011) 1.16

Draft genome sequence of Bacillus anthracis BF-1, isolated from Bavarian cattle. J Bacteriol (2012) 1.14

The spore differentiation pathway in the enteric pathogen Clostridium difficile. PLoS Genet (2013) 1.14

Anthrose biosynthetic operon of Bacillus anthracis. J Bacteriol (2008) 1.14

BslA, the S-layer adhesin of B. anthracis, is a virulence factor for anthrax pathogenesis. Mol Microbiol (2009) 1.14

The global regulator CodY regulates toxin gene expression in Bacillus anthracis and is required for full virulence. Infect Immun (2009) 1.12

Anti-toxin antibodies in prophylaxis and treatment of inhalation anthrax. Future Microbiol (2009) 1.11

Frequency and domain specificity of toxin-neutralizing paratopes in the human antibody response to anthrax vaccine adsorbed. Infect Immun (2009) 1.11

Characteristic features in the structure and collagen-binding ability of a thermophilic collagenolytic protease from the thermophile Geobacillus collagenovorans MO-1. J Bacteriol (2006) 1.11

Genome-based bioinformatic selection of chromosomal Bacillus anthracis putative vaccine candidates coupled with proteomic identification of surface-associated antigens. Infect Immun (2003) 1.11

Two capsular polysaccharides enable Bacillus cereus G9241 to cause anthrax-like disease. Mol Microbiol (2011) 1.11

The Bacillus anthracis SleL (YaaH) protein is an N-acetylglucosaminidase involved in spore cortex depolymerization. J Bacteriol (2008) 1.11

Efficient growth inhibition of Bacillus anthracis by knocking out the ribonucleotide reductase tyrosyl radical. Proc Natl Acad Sci U S A (2005) 1.11

Effects of endogenous D-alanine synthesis and autoinhibition of Bacillus anthracis germination on in vitro and in vivo infections. Infect Immun (2007) 1.11

Targeting the anthrax receptors, TEM-8 and CMG-2, for anti-angiogenic therapy. Front Biosci (Landmark Ed) (2011) 1.10

Bacillus anthracis HssRS signalling to HrtAB regulates haem resistance during infection. Mol Microbiol (2009) 1.10

Detection of a luxS-signaling molecule in Bacillus anthracis. Infect Immun (2003) 1.10

Updating perspectives on the initiation of Bacillus anthracis growth and dissemination through its host. Infect Immun (2012) 1.10

The Bacillus anthracis cholesterol-dependent cytolysin, Anthrolysin O, kills human neutrophils, monocytes and macrophages. BMC Microbiol (2006) 1.09

Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis--one species on the basis of genetic evidence. Appl Environ Microbiol (2000) 7.87

Bacterial SLH domain proteins are non-covalently anchored to the cell surface via a conserved mechanism involving wall polysaccharide pyruvylation. EMBO J (2000) 2.66

The sacT gene regulating the sacPA operon in Bacillus subtilis shares strong homology with transcriptional antiterminators. J Bacteriol (1990) 2.40

The incompatibility between the PlcR- and AtxA-controlled regulons may have selected a nonsense mutation in Bacillus anthracis. Mol Microbiol (2001) 2.20

Characterization of the Bacillus anthracis S-layer: cloning and sequencing of the structural gene. J Bacteriol (1995) 2.01

Molecular characterization of the Bacillus anthracis main S-layer component: evidence that it is the major cell-associated antigen. Mol Microbiol (1997) 1.96

The three Bacillus anthracis toxin genes are coordinately regulated by bicarbonate and temperature. J Bacteriol (1994) 1.85

Production and cell surface anchoring of functional fusions between the SLH motifs of the Bacillus anthracis S-layer proteins and the Bacillus subtilis levansucrase. Mol Microbiol (1999) 1.65

AtxA activates the transcription of genes harbored by both Bacillus anthracis virulence plasmids. FEMS Microbiol Lett (1997) 1.37

Molecular tools for the study of transcriptional regulation in Bacillus anthracis. Res Microbiol (1996) 1.32

Nucleotide sequence of the sucrase gene of Bacillus subtilis. Gene (1986) 1.30

The capsule and S-layer: two independent and yet compatible macromolecular structures in Bacillus anthracis. J Bacteriol (1998) 1.30

Regulation of pag gene expression in Bacillus anthracis: use of a pag-lacZ transcriptional fusion. FEMS Microbiol Lett (1992) 1.17

Cloning and expression in Escherichia coli of the sucrase gene from Bacillus subtilis. Mol Gen Genet (1982) 1.10

Molecular biology of S-layers. FEMS Microbiol Rev (1997) 1.06

Distinct control sites located upstream from the levansucrase gene of Bacillus subtilis. Mol Microbiol (1987) 1.05

The S-layer homology domain as a means for anchoring heterologous proteins on the cell surface of Bacillus anthracis. J Appl Microbiol (1999) 1.05

Distribution of S-layers on the surface of Bacillus cereus strains: phylogenetic origin and ecological pressure. Environ Microbiol (2001) 1.03

Cell surface-exposed tetanus toxin fragment C produced by recombinant Bacillus anthracis protects against tetanus toxin. Infect Immun (1999) 1.01

Characterization of the precursor form of the exocellular levansucrase from Bacillus subtilis. Biochem Biophys Res Commun (1984) 0.97

Characterization of a plasmid region involved in Bacillus anthracis toxin production and pathogenesis. Int J Med Microbiol (2000) 0.95

A general strategy for identification of S-layer genes in the Bacillus cereus group: molecular characterization of such a gene in Bacillus thuringiensis subsp. galleriae NRRL 4045. Microbiology (2001) 0.91

Identification of CodY targets in Bacillus anthracis by genome-wide in vitro binding analysis. J Bacteriol (2013) 0.89

Co-existence of clpB and clpC in the Bacillaceae. FEMS Microbiol Lett (1999) 0.85