M A Shuman

Author PubWeight™ 95.60‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption. Neoplasia 2001 4.22
2 A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation. J Cell Biol 1985 3.02
3 Detection and sequence of mutations in the factor VIII gene of haemophiliacs. Nature 1985 2.30
4 Prothrombin is activated on vascular endothelial cells by factor Xa and calcium. Proc Natl Acad Sci U S A 1983 2.06
5 Redistribution of alpha-granules and their contents in thrombin-stimulated platelets. J Cell Biol 1984 2.06
6 Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue. Proc Natl Acad Sci U S A 1999 2.01
7 Prevention of metastasis by inhibition of the urokinase receptor. Proc Natl Acad Sci U S A 1993 1.82
8 Vascular endothelial growth factor and basic fibroblast growth factor urine levels as predictors of outcome in hormone-refractory prostate cancer patients: a cancer and leukemia group B study. Cancer Res 2001 1.71
9 Characterization of a human Kaposi's sarcoma cell line that induces angiogenic tumors in animals. AIDS 1994 1.68
10 Characterization of the effects of cultured vascular cells on the activation of blood coagulation. Blood 1983 1.63
11 Development of antithrombin antibodies following surgery in patients with prosthetic cardiac valves. Blood 1988 1.60
12 Identification of a missense mutation in the factor VIII gene of a mild hemophiliac. Science 1986 1.60
13 An AIDS-related cytotoxic autoantibody reacts with a specific antigen on stimulated CD4+ T cells. Nature 1987 1.57
14 The measurement of thrombin in clotting blood by radioimmunoassay. J Clin Invest 1976 1.56
15 Thrombin-cellular interactions. Ann N Y Acad Sci 1986 1.47
16 The platelet fibrinogen receptor: an immunogold-surface replica study of agonist-induced ligand binding and receptor clustering. J Cell Biol 1987 1.47
17 Urokinase receptor antagonists inhibit angiogenesis and primary tumor growth in syngeneic mice. Cancer Res 1996 1.45
18 Anaphylactoid reactions to vascular graft material presenting with vasodilation and subsequent disseminated intravascular coagulation. Anesthesiology 1989 1.39
19 Biogenesis of the platelet receptor for fibrinogen: evidence for separate precursors for glycoproteins IIb and IIIa. Proc Natl Acad Sci U S A 1986 1.37
20 Retracted Target platelet antigen in homosexual men with immune thrombocytopenia. N Engl J Med 1985 1.36
21 The urokinase receptor is expressed in invasive breast cancer but not in normal breast tissue. Cancer Res 1994 1.36
22 Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth. Cancer Res 1996 1.35
23 Platelet glycoprotein IIb. Chromosomal localization and tissue expression. J Clin Invest 1987 1.31
24 Cloning of glycoprotein IIIa cDNA from human erythroleukemia cells and localization of the gene to chromosome 17. Blood 1988 1.27
25 Endocytosis of fibrinogen into megakaryocyte and platelet alpha-granules is mediated by alpha IIb beta 3 (glycoprotein IIb-IIIa) Blood 1993 1.25
26 Co-expression of urokinase, urokinase receptor and PAI-1 is necessary for optimum invasiveness of cultured lung cancer cells. Int J Cancer 1995 1.23
27 Immunohistochemical localization of membrane and alpha-granule proteins in human megakaryocytes: application to plastic-embedded bone marrow biopsy specimens. Blood 1986 1.19
28 Effects of urokinase receptor occupancy on plasmin generation and proteolysis of basement membrane by human tumor cells. Blood 1991 1.17
29 Incorporation of a circulating protein into megakaryocyte and platelet granules. Proc Natl Acad Sci U S A 1987 1.14
30 Characteristics of the membrane defect in the hereditary stomatocytosis syndrome. Blood 1975 1.11
31 The zymogen forms of blood coagulation factor XIII bind specifically to fibrinogen. J Biol Chem 1982 1.10
32 Physical linkage of the genes for platelet membrane glycoproteins IIb and IIIa. Proc Natl Acad Sci U S A 1988 1.08
33 The binding of human and bovine thrombin to human platelets. Blood 1976 1.08
34 The perturbation of thrombin binding to human platelets by anions. J Clin Invest 1975 1.07
35 Optimal techniques for the immunocytochemical demonstration of beta-thromboglobulin, platelet factor 4, and fibrinogen in the alpha granules of unstimulated platelets. Histochem J 1984 1.06
36 Incorporation of intravenously injected albumin, immunoglobulin G, and fibrinogen in guinea pig megakaryocyte granules. J Clin Invest 1989 1.06
37 Thrombopoietin levels in patients with cirrhosis before and after orthotopic liver transplantation. Ann Intern Med 1997 1.03
38 Relationship between secretion of platelet Factor 4 and thrombin generation during in vitro blood clotting. J Clin Invest 1980 1.02
39 Identification of an abnormal gene for the GPIIIa subunit of the platelet fibrinogen receptor resulting in Glanzmann's thrombasthenia. Blood 1990 0.98
40 Activation of plasminogen by tissue plasminogen activator on normal and thrombasthenic platelets: effects on surface proteins and platelet aggregation. Blood 1986 0.94
41 The number of receptors for factor VII correlates with the ability of cultured cells to initiate coagulation. Blood 1984 0.94
42 Thrombin generation and secretion of platelet Factor 4 during blood clotting. J Clin Invest 1978 0.94
43 Immunohistochemical localization of the plasminogen activator inhibitor-1 in breast cancer. Int J Cancer 1995 0.94
44 Topographic distribution of a granule membrane protein (GMP-140) that is expressed on the platelet surface after activation: an immunogold-surface replica study. Blood Cells 1986 0.93
45 Internalization and degradation of thrombin and up regulation of thrombin-binding sites in corneal endothelial cells. J Biol Chem 1981 0.92
46 Specific binding of blood coagulation factor XIIIa to thrombin-stimulated platelets. J Biol Chem 1984 0.90
47 Kistrin, an integrin antagonist, blocks endocytosis of fibrinogen into guinea pig megakaryocyte and platelet alpha-granules. J Clin Invest 1993 0.89
48 Human platelets and megakaryocytes contain alternately spliced glycoprotein IIb mRNAs. J Biol Chem 1990 0.89
49 The isolation of vascular endothelial cell lines with altered cell surface and platelet-binding properties. Cell 1978 0.89
50 Acquired Bernard-Soulier syndrome. Evidence for the role of a 210,000-molecular weight protein in the interaction of platelets with von Willebrand factor. J Clin Invest 1985 0.87
51 The transglutaminase in vascular cells and tissues could provide an alternate pathway for fibrin stabilization. Blood 1987 0.87
52 Cleavage of blood coagulation factor XIII and fibrinogen by thrombin during in vitro clotting. J Clin Invest 1985 0.86
53 Thrombin-induced platelet secretion. Further evidence for a specific pathway. J Clin Invest 1979 0.86
54 Inhibition of prostate cancer neovascularization and growth by urokinase-plasminogen activator receptor blockade. Cancer Res 1997 0.86
55 Effects of cellular transformation on expression of plasminogen activator inhibitors 1 and 2. Evidence for independent regulation. J Biol Chem 1989 0.86
56 Characterization of the interaction between factor Xa and bovine aortic endothelial cells. Biochim Biophys Acta 1985 0.85
57 Localization of the gene for coagulation factor XIII a-chain to chromosome 6 and identification of sites of synthesis. J Clin Invest 1987 0.85
58 Identification of normal human peripheral blood monocytes and liver as sites of synthesis of coagulation factor XIII a-chain. Blood 1987 0.85
59 Endothelial cell and platelet binding sites for thrombin. Ann N Y Acad Sci 1981 0.85
60 Patterns of protease production during prostate cancer progression: proteomic evidence for cascades in a transgenic model. Prostate Cancer Prostatic Dis 2003 0.84
61 Posttransfusion purpura associated with an autoantibody directed against a previously undefined platelet antigen. Blood 1987 0.84
62 Effect of cell density on thrombin binding to a specific site on bovine vascular endothelial cells. J Cell Biol 1981 0.83
63 Covalent binding of thrombin to specific sites on corneal endothelial cells. Biochemistry 1981 0.82
64 Radioisotopic measurement of plasma kallikrein. Thromb Res 1982 0.82
65 In vivo defibrination results in markedly decreased amounts of fibrinogen in rat megakaryocytes and platelets. Am J Pathol 1990 0.82
66 Death-defying yeast identify novel apoptosis genes. Cell 1998 0.81
67 The origin of platelet alpha-granule proteins. Prog Clin Biol Res 1990 0.80
68 Synthesis of plasminogen activator by bovine corneal endothelial cells. Exp Eye Res 1979 0.79
69 Circulating thrombopoietin concentrations in thrombocytopenic patients, including cancer patients following chemotherapy, with or without peripheral blood progenitor cell transplantation. Br J Haematol 1996 0.79
70 Evidence that a 210,000-molecular-weight glycoprotein (GP 210) serves as a platelet Fc receptor. J Clin Invest 1987 0.79
71 Quinidine purpura: evidence that glycoprotein V is a target platelet antigen. Blood 1986 0.79
72 Adenocarcinoma of Skene's duct associated with a systemic coagulopathy. Gynecol Oncol 1985 0.79
73 Immunogold-surface replica study of ADP-induced ligand binding and fibrinogen receptor clustering in human platelets. Am J Anat 1989 0.79
74 Combined idiopathic neutropenia and thrombocytopenia: evidence for an immune basis for the syndrome. Ann Intern Med 1980 0.79
75 Management of treatment failures in thrombotic thrombocytopenic purpura. Am J Hematol 1986 0.78
76 A nonradioactive assay for type IV collagen degradation. Anal Biochem 1990 0.78
77 Proliferation and differentiation of bovine corneal endothelial cells in culture. Metab Pediatr Syst Ophthalmol 1982 0.78
78 Endocytosis of fibrinogen into hamster megakaryocyte alpha granules is dependent on a dimeric gamma A configuration. Blood 1995 0.78
79 Thrombin increases expression of urokinase receptor by activation of the thrombin receptor. Invest Ophthalmol Vis Sci 1995 0.77
80 Urokinase binding to bovine corneal endothelial cells. Exp Eye Res 1985 0.77
81 Decreased prostate cancer cell migration by inhibition of the insulin-like growth factor II/Mannose-6-Phosphate receptor. Urol Oncol 2011 0.77
82 Differential effect of platelets on plasminogen activation by tissue plasminogen activator, urokinase, and streptokinase. Thromb Res 1990 0.76
83 Interferon-induced thrombocytopenia: is it time for thrombopoietin. Hepatology 1998 0.75
84 Congenital thrombotic disorders. Am J Hematol 1986 0.75
85 Enhancement of prothrombin activation on platelets by endothelial cells and mechanism of activation of factor V. Thromb Res 1987 0.75
86 Acquired cyclic neutropenia: successful treatment with prednisone. Am J Hematol 1982 0.75
87 Letter: Polycythemia vera and acute leukemia. Ann Intern Med 1975 0.75
88 Aplastic anemia complicating systemic lupus erythematosus: response to androgens in two patients. Am J Hematol 1984 0.75
89 Retraction. Target platelet antigen in homosexual men with immune thrombocytopenia. N Engl J Med 1991 0.75
90 Prophylactic heparin in APL. Blood 1987 0.75