Published in J Immunol on October 15, 2001
The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity (2008) 10.55
Increased expression of interleukin 17 in inflammatory bowel disease. Gut (2003) 9.16
Structure and signalling in the IL-17 receptor family. Nat Rev Immunol (2009) 6.38
IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice. J Clin Invest (2008) 3.64
The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease. Clin Exp Immunol (2007) 3.51
Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites. Immunol Rev (2008) 3.33
The role of T-cell interleukin-17 in conducting destructive arthritis: lessons from animal models. Arthritis Res Ther (2004) 2.54
A novel subset of CD4(+) T(H)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma. J Exp Med (2010) 2.53
Blocking of interleukin-17 during reactivation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and interleukin-1. Am J Pathol (2005) 2.26
Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F. J Immunol (2007) 2.24
Structure-function relationships in the IL-17 receptor: implications for signal transduction and therapy. Cytokine (2008) 2.19
IL-17 expression by breast-cancer-associated macrophages: IL-17 promotes invasiveness of breast cancer cell lines. Breast Cancer Res (2008) 1.80
IL-17 contributes to angiogenesis in rheumatoid arthritis. J Immunol (2010) 1.57
IL-17F: regulation, signaling and function in inflammation. Cytokine (2009) 1.56
The interleukin-17 cytokine family: critical players in host defence and inflammatory diseases. Immunology (2011) 1.53
IL-17 Expression by macrophages is associated with proliferative inflammatory atrophy lesions in prostate cancer patients. Int J Clin Exp Pathol (2011) 1.52
Angiogenesis drives psoriasis pathogenesis. Int J Exp Pathol (2009) 1.49
Thymic stromal lymphopoietin, OX40-ligand, and interleukin-25 in allergic responses. Clin Exp Allergy (2009) 1.49
Regulation and pro-inflammatory function of interleukin-17 family cytokines. Immunol Rev (2008) 1.36
The influence of polymorphisms of interleukin-17A and interleukin-17F genes on the susceptibility to ulcerative colitis. J Clin Immunol (2007) 1.34
Up for Mischief? IL-17/Th17 in the tumour microenvironment. Oncogene (2010) 1.32
A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303. Clin Cancer Res (2011) 1.26
The IL-17 cytokine family and their role in allergic inflammation. Curr Opin Immunol (2008) 1.23
Recent advances in asthma genetics. Respir Res (2008) 1.23
Interleukin-17 causes Rho-kinase-mediated endothelial dysfunction and hypertension. Cardiovasc Res (2012) 1.19
The IL-17 family cytokines in immunity and disease. J Clin Immunol (2010) 1.16
The potential role of interleukin-17 in severe asthma. Curr Allergy Asthma Rep (2011) 1.15
Evolutionary divergence and functions of the human interleukin (IL) gene family. Hum Genomics (2010) 1.15
Th 17 cells interplay with Foxp3+ Tregs in regulation of inflammation and autoimmunity. Front Biosci (Landmark Ed) (2010) 1.11
A protective role by interleukin-17F in colon tumorigenesis. PLoS One (2012) 1.08
Differentiation and function of pro-inflammatory Th17 cells. Microbes Infect (2009) 1.05
Phenotype of CD4+ T cell subsets that develop following mouse facial nerve axotomy. Brain Behav Immun (2007) 1.01
Lamprey (Lethenteron japonicum) IL-17 upregulated by LPS-stimulation in the skin cells. Immunogenetics (2007) 1.01
Improved survival, vascular differentiation and wound healing potential of stem cells co-cultured with endothelial cells. PLoS One (2011) 0.98
IL-17 contributes to the development of chronic rejection in a murine heart transplant model. J Clin Immunol (2010) 0.98
The role of interleukin 17 in tumour proliferation, angiogenesis, and metastasis. Mediators Inflamm (2014) 0.98
Shared signaling systems in myeloid cell-mediated muscle regeneration. Development (2014) 0.95
Therapeutic potential and challenges of natural killer cells in treatment of solid tumors. Front Immunol (2015) 0.93
Regulatory mechanisms of helper T cell differentiation: new lessons learned from interleukin 17 family cytokines. Pharmacol Ther (2008) 0.93
Barriers to preclinical investigations of anti-dengue immunity and dengue pathogenesis. Nat Rev Microbiol (2013) 0.91
Clinical and immunological responses in ocular demodecosis. J Korean Med Sci (2011) 0.89
Anti-inflammatory treatment of uveitis with biologicals: new treatment options that reflect pathogenetic knowledge of the disease. Graefes Arch Clin Exp Ophthalmol (2010) 0.88
Interleukin 17A promotes gastric cancer invasiveness via NF-κB mediated matrix metalloproteinases 2 and 9 expression. PLoS One (2014) 0.88
Role of TH17 cytokines in the control of colorectal cancer. Oncoimmunology (2013) 0.87
Genetic polymorphisms of interleukin 17A and interleukin 17F and their association with inflammatory bowel disease in a Chinese Han population. Inflamm Res (2013) 0.87
IFN-γ induction by neutrophil-derived IL-17A homodimer augments pulmonary antibacterial defense. Mucosal Immunol (2015) 0.86
IL-17F-induced IL-11 release in bronchial epithelial cells via MSK1-CREB pathway. Am J Physiol Lung Cell Mol Physiol (2009) 0.86
Macrophages in homeostatic immune function. Front Physiol (2014) 0.86
A distinct regulatory role of Th17 cytokines IL-17A and IL-17F in chemokine secretion from lung microvascular endothelial cells. Inflammation (2012) 0.85
Potential involvement of IL-17F in asthma. J Immunol Res (2014) 0.85
The transcriptomic response of rat hepatic stellate cells to endotoxin: implications for hepatic inflammation and immune regulation. PLoS One (2013) 0.84
The use of genomic information to optimize cancer chemotherapy. Semin Oncol (2011) 0.84
Cytokine-Induced Modulation of Colorectal Cancer. Front Oncol (2016) 0.84
The other T helper cells in asthma pathogenesis. J Allergy (Cairo) (2010) 0.84
Grape seed proanthocyanidin extract inhibits interleukin-17-induced interleukin-6 production via MAPK pathway in human pulmonary epithelial cells. Naunyn Schmiedebergs Arch Pharmacol (2011) 0.83
Th17 cytokines induce pro-fibrotic cytokines release from human eosinophils. Respir Res (2013) 0.83
Angiogenesis in rheumatoid arthritis is fostered directly by toll-like receptor 5 ligation and indirectly through interleukin-17 induction. Arthritis Rheum (2013) 0.83
Regulation of IL-17 family members by adrenal hormones during experimental sepsis in mice. Am J Pathol (2013) 0.82
Cloning and characterization of rainbow trout interleukin-17A/F2 (IL-17A/F2) and IL-17 receptor A: expression during infection and bioactivity of recombinant IL-17A/F2. Infect Immun (2012) 0.82
IL-17F Induces CCL20 in Bronchial Epithelial Cells. J Allergy (Cairo) (2011) 0.81
Evolution of the IL17 receptor family in chordates: a new subfamily IL17REL. Immunogenetics (2011) 0.81
IL-25/IL-33-responsive TH2 cells characterize nasal polyps with a default TH17 signature in nasal mucosa. J Allergy Clin Immunol (2015) 0.80
Differential effects of interleukin-17 receptor signaling on innate and adaptive immunity during central nervous system bacterial infection. J Neuroinflammation (2012) 0.79
Modulation of innate host factors by Mycobacterium avium complex in human macrophages includes interleukin 17. J Infect Dis (2012) 0.79
MicroRNAs and other mechanisms regulate interleukin-17 cytokines and receptors. Front Biosci (Elite Ed) (2012) 0.79
Cross Talk between Proliferative, Angiogenic, and Cellular Mechanisms Orchestred by HIF-1α in Psoriasis. Mediators Inflamm (2015) 0.78
IL-17A in human respiratory diseases: innate or adaptive immunity? Clinical implications. Clin Dev Immunol (2013) 0.78
Cytokine crowdsourcing: multicellular production of TH17-associated cytokines. J Leukoc Biol (2014) 0.78
IL-17B Can Impact on Endothelial Cellular Traits Linked to Tumour Angiogenesis. J Oncol (2010) 0.77
Therapeutic Potential of IL-17-Mediated Signaling Pathway in Autoimmune Liver Diseases. Mediators Inflamm (2015) 0.76
Prenatal alcohol exposure potentiates chronic neuropathic pain, spinal glial and immune cell activation and alters sciatic nerve and DRG cytokine levels. Brain Behav Immun (2016) 0.76
Increased Interleukin-17F is Associated with Elevated Autoantibody Levels and More Clinically Relevant Than Interleukin-17A in Primary Sjögren's Syndrome. J Immunol Res (2017) 0.75
Novel SNPs in IL-17F and IL-17A genes associated with somatic cell count in Chinese Holstein and Inner-Mongolia Sanhe cattle. J Anim Sci Biotechnol (2017) 0.75
Interleukin-17F 7488T/C polymorphism is associated with protection against asthma: a meta-analysis. Int J Clin Exp Med (2015) 0.75
IL-17F induces IL-6 via TAK1-NFκB pathway in airway smooth muscle cells. Immun Inflamm Dis (2017) 0.75
Association between IL-17F rs763780 polymorphism and susceptibility of asthma: a meta-analysis. Int J Clin Exp Med (2015) 0.75
Immune analysis of expression of IL-17 relative ligands and their receptors in bladder cancer: comparison with polyp and cystitis. BMC Immunol (2016) 0.75
IL-10 and IL-17F Promoter Single Nucleotide Polymorphism and Asthma: A Case-Control Study in South India. Lung (2015) 0.75
Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice. J Clin Invest (1997) 7.58
Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently. Cell (1992) 5.87
A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency. Immunity (1996) 5.64
NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2. Oncogene (2006) 3.91
Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance. J Biol Chem (2001) 3.86
Transcription factors, normal myeloid development, and leukemia. Blood (1997) 3.71
Characterization of human bone marrow fibroblast colony-forming cells (CFU-F) and their progeny. Blood (1980) 3.51
The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1. Mol Cell Biol (1993) 2.84
Expression of Ia-like antigen molecules on human granulocytes during early phases of differentiation. Proc Natl Acad Sci U S A (1977) 2.80
Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1. J Exp Med (1997) 2.79
Transplantation of umbilical cord blood after myeloablative therapy: analysis of engraftment. Blood (1992) 2.77
Pilot study of a point-of-use decision support tool for cancer clinical trials eligibility. J Am Med Inform Assoc (1999) 2.60
Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors. Cell (1992) 2.50
Allogeneic sibling umbilical-cord-blood transplantation in children with malignant and non-malignant disease. Lancet (1995) 2.40
Chemokines: signal lamps for trafficking of T and B cells for development and effector function. J Leukoc Biol (1999) 2.34
Diagnostic electron microscopy of faeces. II. Acute gastroenteritis associated with reovirus-like particles. J Clin Pathol (1974) 2.33
Life-styles, adaptive strategies, and sexual behaviors of homeless adolescents. Hosp Community Psychiatry (1993) 2.28
Bortezomib in patients with relapsed or refractory mantle cell lymphoma: updated time-to-event analyses of the multicenter phase 2 PINNACLE study. Ann Oncol (2008) 2.23
Stimulation of megakaryocyte and platelet production by a single dose of recombinant human thrombopoietin in patients with cancer. Ann Intern Med (1997) 2.22
Selective modulation of human natural killer cells in vivo after prolonged infusion of low dose recombinant interleukin 2. J Clin Invest (1993) 2.18
RARs and RXRs: evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo. EMBO J (1993) 2.17
Health status and access to health services among the urban homeless. Am J Public Health (1986) 2.15
Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells. Nat Med (2000) 2.09
Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies. Clin Cancer Res (1997) 2.08
Genesis, a winged helix transcriptional repressor with expression restricted to embryonic stem cells. J Biol Chem (1996) 2.02
1st International consensus guidelines for advanced breast cancer (ABC 1). Breast (2012) 1.96
Identification of lactoferrin as the granulocyte-derived inhibitor of colony-stimulating activity production. J Exp Med (1978) 1.94
Multiple inhibitory cytokines induce deregulated progenitor growth and apoptosis in hematopoietic cells from Fac-/- mice. Blood (1998) 1.93
Comparative analysis of the influences of human gamma, alpha and beta interferons on human multipotential (CFU-GEMM), erythroid (BFU-E) and granulocyte-macrophage (CFU-GM) progenitor cells. J Immunol (1983) 1.88
Isolation and characterization of Exodus-2, a novel C-C chemokine with a unique 37-amino acid carboxyl-terminal extension. J Immunol (1997) 1.87
Vi reaction in Hong Kong. Br Med J (1967) 1.85
Familial backgrounds and risk behaviors of youth with thrownaway experiences. J Adolesc (1998) 1.78
A retinoic acid response element is present in the mouse cellular retinol binding protein I (mCRBPI) promoter. EMBO J (1991) 1.74
Membrane-bound Steel factor induces more persistent tyrosine kinase activation and longer life span of c-kit gene-encoded protein than its soluble form. Blood (1995) 1.69
Low levels of erythroid and myeloid progenitors in thrombopoietin-and c-mpl-deficient mice. Blood (1996) 1.63
Limitation of excessive myelopoiesis by the intrinsic modulation of macrophage-derived prostaglandin E. Science (1978) 1.60
CK beta-11/macrophage inflammatory protein-3 beta/EBI1-ligand chemokine is an efficacious chemoattractant for T and B cells. J Immunol (1998) 1.60
Characterization of the DNA-binding properties of the myeloid zinc finger protein MZF1: two independent DNA-binding domains recognize two DNA consensus sequences with a common G-rich core. Mol Cell Biol (1994) 1.60
Mouse retinoic acid receptor alpha 2 isoform is transcribed from a promoter that contains a retinoic acid response element. Proc Natl Acad Sci U S A (1991) 1.57
Paclitaxel sensitivity of breast cancer cells with constitutively active NF-kappaB is enhanced by IkappaBalpha super-repressor and parthenolide. Oncogene (2000) 1.57
Characterization of the ets oncogene family member, fli-1. J Biol Chem (1993) 1.57
Cloning of BRAK, a novel divergent CXC chemokine preferentially expressed in normal versus malignant cells. Biochem Biophys Res Commun (1999) 1.56
Effects of recombinant human granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndromes. N Engl J Med (1987) 1.55
SCID mice as an in vivo model of human cord blood hematopoiesis. Blood Cells (1994) 1.54
Regulation of macrophage and granulocyte proliferation. Specificities of prostaglandin E and lactoferrin. J Exp Med (1979) 1.51
Biased suppression of hematopoiesis and multiple developmental defects in chimeric mice containing Shp-2 mutant cells. Mol Cell Biol (1998) 1.50
Nuclear factors bind to regulatory regions of the mouse kappa immunoglobulin gene. Nucleic Acids Res (1986) 1.48
Hematopoietic defects in mice lacking the sialomucin CD34. Blood (1996) 1.46
Cloning and characterization of exodus, a novel beta-chemokine. Blood (1997) 1.44
Mzf1 controls cell proliferation and tumorigenesis. Genes Dev (2001) 1.43
Differential chemotactic behavior of developing T cells in response to thymic chemokines. Blood (1998) 1.42
Inducible production of human macrophage growth factor, CSF-1. Blood (1986) 1.40
Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling. J Exp Med (2000) 1.38
Macrophage migration inhibitory factor release by macrophages after ingestion of Plasmodium chabaudi-infected erythrocytes: possible role in the pathogenesis of malarial anemia. Infect Immun (2000) 1.37
Forkhead box A1 expression in breast cancer is associated with luminal subtype and good prognosis. J Clin Pathol (2007) 1.36
Involvement of SH2-containing phosphotyrosine phosphatase Syp in erythropoietin receptor signal transduction pathways. J Biol Chem (1995) 1.34
MRG1, the product of a melanocyte-specific gene related gene, is a cytokine-inducible transcription factor with transformation activity. Proc Natl Acad Sci U S A (1998) 1.33
Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: implications of p53 mutation or isoform expression on breast cancer cell invasion. Oncogene (2006) 1.33
Inhibition of human erythropoietic colony formation in culture by treatment with Ia antisera. J Exp Med (1978) 1.32
Interleukin 2 signaling involves the phosphorylation of Stat proteins. Proc Natl Acad Sci U S A (1995) 1.32
Repression of transforming-growth-factor-beta-mediated transcription by nuclear factor kappaB. Biochem J (2000) 1.31
Can the poor adhere? Incentives for adherence to TB prevention in homeless adults. Int J Tuberc Lung Dis (2004) 1.31
P2Y1-receptors in human platelets which are pharmacologically distinct from P2Y(ADP)-receptors. Br J Pharmacol (1998) 1.30
Repression of GADD153/CHOP by NF-kappaB: a possible cellular defense against endoplasmic reticulum stress-induced cell death. Oncogene (2001) 1.30
Immature human cord blood progenitors engraft and proliferate to high levels in severe combined immunodeficient mice. Blood (1994) 1.29
Expression of sialyl-Lewis X, an E-selectin ligand, in inflammation, immune processes, and lymphoid tissues. Am J Pathol (1992) 1.29
Myelosuppressive effects in vivo of purified recombinant murine macrophage inflammatory protein-1 alpha. J Immunol (1992) 1.28
Glucocorticoid-dependent oncogenic transformation by type 16 but not type 11 human papilloma virus DNA. Nature (1988) 1.28
Adeno-associated virus 2-mediated high efficiency gene transfer into immature and mature subsets of hematopoietic progenitor cells in human umbilical cord blood. J Exp Med (1994) 1.26
Cell-free granulocyte colony inhibiting activity derived from human polymorphonuclear neutrophils. Exp Hematol (1977) 1.26
Analysis of engraftment, graft-versus-host disease, and immune recovery following unrelated donor cord blood transplantation. Blood (2000) 1.26
Characterization of adult human marrow hematopoietic progenitors highly enriched by two-color cell sorting with My10 and major histocompatibility class II monoclonal antibodies. J Immunol (1987) 1.26
CD69 is a stimulatory receptor for natural killer cell and its cytotoxic effect is blocked by CD94 inhibitory receptor. Immunology (1999) 1.26
Control of EVI-1 oncogene expression in metastatic breast cancer cells through microRNA miR-22. Oncogene (2010) 1.26
Inhibition of selective signaling events in natural killer cells recognizing major histocompatibility complex class I. Proc Natl Acad Sci U S A (1995) 1.25
Interleukin 2 receptor gamma chain expression on resting and activated lymphoid cells. J Exp Med (1994) 1.25
Flt3 signaling involves tyrosyl-phosphorylation of SHP-2 and SHIP and their association with Grb2 and Shc in Baf3/Flt3 cells. J Leukoc Biol (1999) 1.24
CNI-1493 inhibits monocyte/macrophage tumor necrosis factor by suppression of translation efficiency. Proc Natl Acad Sci U S A (1996) 1.22
Ligand-dependent polyubiquitination of c-kit gene product: a possible mechanism of receptor down modulation in M07e cells. Blood (1994) 1.22
Interferon-inducible protein 10 and macrophage inflammatory protein-1 alpha inhibit growth factor stimulation of Raf-1 kinase activity and protein synthesis in a human growth factor-dependent hematopoietic cell line. J Biol Chem (1995) 1.20
Identification of leukemia-associated inhibitory activity as acidic isoferritins. A regulatory role for acidic isoferritins in the production of granulocytes and macrophages. J Exp Med (1981) 1.20
Developmental regulation of a mucinlike glycoprotein selectively expressed on natural killer cells. J Exp Med (1993) 1.20
Effects of recombinant human colony stimulating factors (CSF) (granulocyte-macrophage CSF, granulocyte CSF, and CSF-1) on human monocyte/macrophage differentiation. J Immunol (1989) 1.18
Oestrogen-receptor-positive breast cancer: towards bridging histopathological and molecular classifications. J Clin Pathol (2008) 1.18
Evolving pathogens in allogeneic bone marrow transplantation: increased fatal adenoviral infections. Am J Med (1995) 1.17
Antisense oligonucleotides from the stage-specific myeloid zinc finger gene MZF-1 inhibit granulopoiesis in vitro. J Exp Med (1991) 1.17
Transcriptional induction of pim-1 protein kinase gene expression by interferon gamma and posttranscriptional effects on costimulation with steel factor. Blood (1995) 1.16
Adeno-associated virus 2-mediated gene transfer in murine hematopoietic progenitor cells. Exp Hematol (1993) 1.16
Abnormal chemokine-induced responses of immature and mature hematopoietic cells from motheaten mice implicate the protein tyrosine phosphatase SHP-1 in chemokine responses. J Exp Med (1999) 1.16
Human interferon-inducible protein 10: expression and purification of recombinant protein demonstrate inhibition of early human hematopoietic progenitors. J Exp Med (1993) 1.15