Published in Glia on November 01, 2001
Autoimmune T cell responses in the central nervous system. Nat Rev Immunol (2009) 4.73
Inflammatory mechanisms in ischemic stroke: role of inflammatory cells. J Leukoc Biol (2010) 4.37
Inflammation as a causative factor in the aetiology of Parkinson's disease. Br J Pharmacol (2007) 2.71
Tumor necrosis factor-alpha triggers a cytokine cascade yielding postoperative cognitive decline. Proc Natl Acad Sci U S A (2010) 2.70
The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses. Neuro Oncol (2006) 2.53
Role of microglia in neurotrauma. Neurotherapeutics (2010) 2.53
Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression. Trends Immunol (2008) 2.46
The molecular profile of microglia under the influence of glioma. Neuro Oncol (2012) 2.38
A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia. J Neurochem (2009) 2.37
Neuroinflammatory mechanisms in Parkinson's disease: potential environmental triggers, pathways, and targets for early therapeutic intervention. Exp Neurol (2007) 2.36
Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis. Immunity (2010) 2.32
Migration and differentiation of neural precursor cells can be directed by microglia. Proc Natl Acad Sci U S A (2003) 2.05
IL-17 receptor signaling and T helper 17-mediated autoimmune demyelinating disease. Trends Immunol (2011) 2.00
Heterogeneous expression of the triggering receptor expressed on myeloid cells-2 on adult murine microglia. J Neurochem (2002) 2.00
MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity. J Exp Med (2010) 2.00
Selective neuronal vulnerability to oxidative stress in the brain. Front Aging Neurosci (2010) 1.96
CX3CR1 deficiency leads to impairment of hippocampal cognitive function and synaptic plasticity. J Neurosci (2011) 1.95
Toll-like receptors in central nervous system glial inflammation and homeostasis. J Neurosci Res (2006) 1.91
Microglial activation and chronic neurodegeneration. Neurotherapeutics (2010) 1.87
Microglia as liaisons between the immune and central nervous systems: functional implications for multiple sclerosis. Glia (2002) 1.74
Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential. Clin Sci (Lond) (2011) 1.73
Fractalkine and CX 3 CR1 regulate hippocampal neurogenesis in adult and aged rats. Neurobiol Aging (2009) 1.72
CD4-positive T cell-mediated neuroprotection requires dual compartment antigen presentation. J Neurosci (2004) 1.71
Perioperative cognitive decline in the aging population. Mayo Clin Proc (2011) 1.66
Amphetamine toxicities: classical and emerging mechanisms. Ann N Y Acad Sci (2010) 1.62
The impact of IL-1 modulation on the development of lipopolysaccharide-induced cognitive dysfunction. Crit Care (2010) 1.59
Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation. J Neuroinflammation (2005) 1.57
Immunotherapeutic approaches for glioma. Crit Rev Immunol (2009) 1.55
Anti-inflammatory and immunomodulatory mechanisms of mesenchymal stem cell transplantation in experimental traumatic brain injury. J Neuroinflammation (2013) 1.53
Cannabinoid CB(2) receptors modulate ERK-1/2 kinase signalling and NO release in microglial cells stimulated with bacterial lipopolysaccharide. Br J Pharmacol (2012) 1.47
Toll-like receptor 2 (TLR2) is pivotal for recognition of S. aureus peptidoglycan but not intact bacteria by microglia. Glia (2005) 1.46
The role of antigen presenting cells in multiple sclerosis. Biochim Biophys Acta (2010) 1.38
Inflammation and the neurovascular unit in the setting of focal cerebral ischemia. Neuroscience (2008) 1.37
Temporal changes in cell marker expression and cellular infiltration in a controlled cortical impact model in adult male C57BL/6 mice. PLoS One (2012) 1.36
Efficient isolation of live microglia with preserved phenotypes from adult mouse brain. J Neuroinflammation (2012) 1.36
Immunopathogenesis of brain abscess. J Neuroinflammation (2004) 1.32
Retinal microglial activation and inflammation induced by amadori-glycated albumin in a rat model of diabetes. Diabetes (2011) 1.31
The role of environmental exposures in neurodegeneration and neurodegenerative diseases. Toxicol Sci (2011) 1.31
Delayed mGluR5 activation limits neuroinflammation and neurodegeneration after traumatic brain injury. J Neuroinflammation (2012) 1.31
Abeta-induced meningoencephalitis is IFN-gamma-dependent and is associated with T cell-dependent clearance of Abeta in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A (2006) 1.30
Microglia and the control of autoreactive T cell responses. Neurochem Int (2006) 1.28
Features of microglia and neuroinflammation relevant to environmental exposure and neurotoxicity. Int J Environ Res Public Health (2011) 1.27
P2X7 receptors control 2-arachidonoylglycerol production by microglial cells. Proc Natl Acad Sci U S A (2004) 1.25
The cortical innate immune response increases local neuronal excitability leading to seizures. Brain (2009) 1.25
Morphine and HIV-Tat increase microglial-free radical production and oxidative stress: possible role in cytokine regulation. J Neurochem (2008) 1.22
Innate and adaptive immunity for the pathobiology of Parkinson's disease. Antioxid Redox Signal (2009) 1.20
Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes. Mol Med (2007) 1.19
Safety and feasibility of countering neurological impairment by intravenous administration of autologous cord blood in cerebral palsy. J Transl Med (2012) 1.16
Mechanisms of immune system activation in glaucoma: oxidative stress-stimulated antigen presentation by the retina and optic nerve head glia. Invest Ophthalmol Vis Sci (2007) 1.16
Intravenous multipotent adult progenitor cell therapy after traumatic brain injury: modulation of the resident microglia population. J Neuroinflammation (2012) 1.15
Central role for MyD88 in the responses of microglia to pathogen-associated molecular patterns. J Immunol (2006) 1.15
Neurogenic exacerbation of microglial and astrocyte responses to Neisseria meningitidis and Borrelia burgdorferi. J Immunol (2008) 1.13
Contrasting effects of human, canine, and hybrid adenovirus vectors on the phenotypical and functional maturation of human dendritic cells: implications for clinical efficacy. J Virol (2007) 1.13
Microglia in infectious diseases of the central nervous system. J Neuroimmune Pharmacol (2009) 1.10
Immunological features of alpha-synuclein in Parkinson's disease. J Cell Mol Med (2008) 1.10
Age related changes in microglial phenotype vary between CNS regions: grey versus white matter differences. Brain Behav Immun (2011) 1.09
Cranial irradiation leads to acute and persistent neuroinflammation with delayed increases in T-cell infiltration and CD11c expression in C57BL/6 mouse brain. Radiat Res (2011) 1.09
Role of brain inflammation in epileptogenesis. Yonsei Med J (2008) 1.09
CXCL10 production from cytomegalovirus-stimulated microglia is regulated by both human and viral interleukin-10. J Virol (2003) 1.08
The changing phenotype of microglia from homeostasis to disease. Transl Neurodegener (2012) 1.06
Absence of TLR4 reduces neurovascular unit and secondary inflammatory process after traumatic brain injury in mice. PLoS One (2013) 1.06
Defective transcription factor activation for proinflammatory gene expression in poly(ADP-ribose) polymerase 1-deficient glia. Proc Natl Acad Sci U S A (2004) 1.06
Defining and designing polymers and hydrogels for neural tissue engineering. Neurosci Res (2011) 1.06
Human and mouse microglia express connexin36, and functional gap junctions are formed between rodent microglia and neurons. J Neurosci Res (2005) 1.05
Neuroimmunological processes in Parkinson's disease and their relation to α-synuclein: microglia as the referee between neuronal processes and peripheral immunity. ASN Neuro (2013) 1.05
Minocycline modulates neuroinflammation independently of its antimicrobial activity in staphylococcus aureus-induced brain abscess. Am J Pathol (2007) 1.05
LRRK2 and neuroinflammation: partners in crime in Parkinson's disease? J Neuroinflammation (2014) 1.05
Novel Abeta peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease. J Neuroinflammation (2005) 1.03
Blood-brain barrier integrity and glial support: mechanisms that can be targeted for novel therapeutic approaches in stroke. Curr Pharm Des (2012) 1.03
S. aureus-dependent microglial activation is selectively attenuated by the cyclopentenone prostaglandin 15-deoxy-Delta12,14- prostaglandin J2 (15d-PGJ2). J Neurochem (2004) 1.03
The role of innate and adaptive immunity in Parkinson's disease. J Parkinsons Dis (2013) 1.03
The paradox of chronic neuroinflammation, systemic immune suppression, autoimmunity after traumatic chronic spinal cord injury. Exp Neurol (2014) 1.02
Microglial derived tumor necrosis factor-α drives Alzheimer's disease-related neuronal cell cycle events. Neurobiol Dis (2013) 1.02
The C terminus of mouse monocyte chemoattractant protein 1 (MCP1) mediates MCP1 dimerization while blocking its chemotactic potency. J Biol Chem (2010) 1.02
Monocyte chemoattractant protein-1 and the blood-brain barrier. Cell Mol Life Sci (2013) 1.02
Japanese encephalitis virus induce immuno-competency in neural stem/progenitor cells. PLoS One (2009) 1.01
Rabies virus-induced activation of mitogen-activated protein kinase and NF-kappaB signaling pathways regulates expression of CXC and CC chemokine ligands in microglia. J Virol (2005) 1.01
Targeted drug delivery to treat pain and cerebral hypoxia. Pharmacol Rev (2013) 1.01
Role of spinal cord glia in the central processing of peripheral pain perception. Neurogastroenterol Motil (2010) 1.01
Frequency, proliferation, and activation of human memory T cells induced by a nonhuman adenovirus. J Virol (2005) 1.00
Staphylococcus aureus-derived peptidoglycan induces Cx43 expression and functional gap junction intercellular communication in microglia. J Neurochem (2005) 1.00
Monocyte and Macrophage Plasticity in Tissue Repair and Regeneration. Am J Pathol (2015) 0.99
Human NK cells kill resting but not activated microglia via NKG2D- and NKp46-mediated recognition. J Immunol (2008) 0.98
Microglial immunoreceptor tyrosine-based activation and inhibition motif signaling in neuroinflammation. Int J Alzheimers Dis (2010) 0.98
Microglial activation by Citrobacter koseri is mediated by TLR4- and MyD88-dependent pathways. J Immunol (2009) 0.97
Microglia and Astrocyte Activation by Toll-Like Receptor Ligands: Modulation by PPAR-gamma Agonists. PPAR Res (2008) 0.97
Brain microglia express steroid-converting enzymes in the mouse. J Steroid Biochem Mol Biol (2008) 0.97
Neural stem/progenitor cells as a promising candidate for regenerative therapy of the central nervous system. Front Cell Neurosci (2012) 0.96
The ubiquitin proteasome system in glia and its role in neurodegenerative diseases. Front Mol Neurosci (2014) 0.96
Gemfibrozil, a lipid-lowering drug, upregulates IL-1 receptor antagonist in mouse cortical neurons: implications for neuronal self-defense. J Immunol (2012) 0.96
T cells specifically targeted to amyloid plaques enhance plaque clearance in a mouse model of Alzheimer's disease. PLoS One (2010) 0.96
Toll-like receptor 2 signaling is a mediator of apoptosis in herpes simplex virus-infected microglia. J Neuroinflammation (2007) 0.96
The evolving landscape of neurotoxicity by unconjugated bilirubin: role of glial cells and inflammation. Front Pharmacol (2012) 0.96
Brucella abortus induces the secretion of proinflammatory mediators from glial cells leading to astrocyte apoptosis. Am J Pathol (2010) 0.96
Imaging robust microglial activation after lipopolysaccharide administration in humans with PET. Proc Natl Acad Sci U S A (2015) 0.96
Neuroinflammation, neurodegeneration, and depression. Neurotox Res (2012) 0.95
The impact of glial activation in the aging brain. Aging Dis (2010) 0.95
Bioinformatics analyses reveal age-specific neuroimmune modulation as a target for treatment of high ethanol drinking. Alcohol Clin Exp Res (2013) 0.94
Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2. J Virol (2008) 0.94
Enteric glial cells and their role in gastrointestinal motor abnormalities: introducing the neuro-gliopathies. World J Gastroenterol (2007) 0.94