Published in J Mol Biol on October 26, 2001
Genome sequence of Haloarcula marismortui: a halophilic archaeon from the Dead Sea. Genome Res (2004) 2.75
Membrane protein crystallization in meso: lipid type-tailoring of the cubic phase. Biophys J (2002) 1.46
Crystallographic structure of xanthorhodopsin, the light-driven proton pump with a dual chromophore. Proc Natl Acad Sci U S A (2008) 1.45
Time-resolved structural studies of protein reaction dynamics: a smorgasbord of X-ray approaches. Acta Crystallogr A (2010) 1.23
Protein conformational changes in the bacteriorhodopsin photocycle: comparison of findings from electron and X-ray crystallographic analyses. PLoS One (2009) 0.98
Structural snapshots of conformational changes in a seven-helix membrane protein: lessons from bacteriorhodopsin. Curr Opin Struct Biol (2009) 0.95
Crystal structure of the bromide-bound D85S mutant of bacteriorhodopsin: principles of ion pumping. Biophys J (2003) 0.90
How environment supports a state: molecular dynamics simulations of two states in bacteriorhodopsin suggest lipid and water compensation. Biophys J (2004) 0.88
Subsecond proton-hole propagation in bacteriorhodopsin. Biophys J (2003) 0.85
Long-distance proton transfer with a break in the bacteriorhodopsin active site. J Am Chem Soc (2009) 0.84
Conversion of a light-driven proton pump into a light-gated ion channel. Sci Rep (2015) 0.83
A transporter converted into a sensor, a phototaxis signaling mutant of bacteriorhodopsin at 3.0 Å. J Mol Biol (2011) 0.82
Propagating structural perturbation inside bacteriorhodopsin: crystal structures of the M state and the D96A and T46V mutants. Biochemistry (2006) 0.82
Electron paramagnetic resonance study of structural changes in the O photointermediate of bacteriorhodopsin. J Mol Biol (2006) 0.81
Characterization and photochemistry of 13-desmethyl bacteriorhodopsin. J Phys Chem B (2005) 0.78
The signal transfer from the receptor NpSRII to the transducer NpHtrII is not hampered by the D75N mutation. Biophys J (2011) 0.77
Stable closure of the cytoplasmic half-channel is required for efficient proton transport at physiological membrane potentials in the bacteriorhodopsin catalytic cycle. Biochemistry (2014) 0.76
Structure of bacteriorhodopsin at 1.55 A resolution. J Mol Biol (1999) 8.17
Structural basis of water-specific transport through the AQP1 water channel. Nature (2002) 6.23
Structural changes in bacteriorhodopsin during ion transport at 2 angstrom resolution. Science (1999) 3.83
Salt-dependent properties of proteins from extremely halophilic bacteria. Bacteriol Rev (1974) 3.66
Halorhodopsin is a light-driven chloride pump. J Biol Chem (1982) 3.24
Proton transfer pathways in bacteriorhodopsin at 2.3 angstrom resolution. Science (1998) 2.89
Thermodynamics and energy coupling in the bacteriorhodopsin photocycle. Biochemistry (1991) 2.78
Electron diffraction of frozen, hydrated protein crystals. Science (1974) 2.56
Glutamic acid 204 is the terminal proton release group at the extracellular surface of bacteriorhodopsin. J Biol Chem (1995) 2.36
Crystal structure of sensory rhodopsin II at 2.4 angstroms: insights into color tuning and transducer interaction. Science (2001) 2.25
Kinetic and spectroscopic evidence for an irreversible step between deprotonation and reprotonation of the Schiff base in the bacteriorhodopsin photocycle. Biochemistry (1991) 2.23
Fluorescent method for the detection of excreted ribonuclease around bacterial colonies. J Bacteriol (1966) 2.08
Water is required for proton transfer from aspartate-96 to the bacteriorhodopsin Schiff base. Biochemistry (1991) 2.06
Light energy conversion in Halobacterium halobium. Microbiol Rev (1978) 1.96
Periodic surface array in Caulobacter crescentus: fine structure and chemical analysis. J Bacteriol (1981) 1.96
Illumination-dependent changes in the intrinsic fluorescence of bacteriorhodopsin. Biochemistry (1978) 1.95
Pathways of the rise and decay of the M photointermediate(s) of bacteriorhodopsin. Biochemistry (1990) 1.91
Pathways of proton release in the bacteriorhodopsin photocycle. Biochemistry (1992) 1.89
Properties of Asp212----Asn bacteriorhodopsin suggest that Asp212 and Asp85 both participate in a counterion and proton acceptor complex near the Schiff base. J Biol Chem (1991) 1.81
The role of Na+ in transport processes of bacterial membranes. Biochim Biophys Acta (1979) 1.81
Spectrophotometric identification of the pigment associated with light-driven primary sodium translocation in Halobacterium halobium. J Biol Chem (1980) 1.80
Dipoles localized at helix termini of proteins stabilize charges. Proc Natl Acad Sci U S A (1991) 1.77
Protein catalysis of the retinal subpicosecond photoisomerization in the primary process of bacteriorhodopsin photosynthesis. Science (1993) 1.75
Bacteriorhodopsin. Curr Opin Struct Biol (2001) 1.74
A linkage of the pKa's of asp-85 and glu-204 forms part of the reprotonation switch of bacteriorhodopsin. Biochemistry (1996) 1.74
Halorhodopsin: a light-driven chloride ion pump. Annu Rev Biophys Biophys Chem (1986) 1.72
Molecular mechanism of spectral tuning in sensory rhodopsin II. Biochemistry (2001) 1.72
Electron microscopy of frozen hydrated biological specimens. J Ultrastruct Res (1976) 1.67
Studies of the electron transport chain of extremely halophilic bacteria. I. Spectrophotometric identification of the cytochromes of Halobacterium cutirubrum. Arch Biochem Biophys (1968) 1.66
The relevance of dose-fractionation in tomography of radiation-sensitive specimens. Ultramicroscopy (1995) 1.65
Limitations to significant information in biological electron microscopy as a result of radiation damage. J Ultrastruct Res (1971) 1.65
Conversion of bacteriorhodopsin into a chloride ion pump. Science (1995) 1.65
Coupling photoisomerization of retinal to directional transport in bacteriorhodopsin. J Mol Biol (2000) 1.61
Radiation damage of purple membrane at low temperature. Ultramicroscopy (1979) 1.60
Light-induced transport in Halobacterium halobium. Methods Enzymol (1979) 1.59
Existence of electrogenic hydrogen ion/sodium ion antiport in Halobacterium halobium cell envelope vesicles. Biochemistry (1976) 1.57
Existence of a proton transfer chain in bacteriorhodopsin: participation of Glu-194 in the release of protons to the extracellular surface. Biochemistry (1998) 1.55
Energy coupling in an ion pump. The reprotonation switch of bacteriorhodopsin. J Mol Biol (1994) 1.49
Electron diffraction analysis of the M412 intermediate of bacteriorhodopsin. Biophys J (1986) 1.47
Protein changes associated with reprotonation of the Schiff base in the photocycle of Asp96-->Asn bacteriorhodopsin. The MN intermediate with unprotonated Schiff base but N-like protein structure. J Biol Chem (1992) 1.42
Deriving the intermediate spectra and photocycle kinetics from time-resolved difference spectra of bacteriorhodopsin. The simpler case of the recombinant D96N protein. Biophys J (1993) 1.42
Light-activated amino acid transport systems in Halobacterium halobium envelope vesicles: role of chemical and electrical gradients. Biochemistry (1977) 1.41
Characterization of metal ion-binding sites in bacteriorhodopsin. J Biol Chem (1986) 1.39
Structure of the N intermediate of bacteriorhodopsin revealed by x-ray diffraction. Proc Natl Acad Sci U S A (1996) 1.39
Molecular orientation of bacteriorhodopsin within the purple membrane of Halobacterium halobium. Proc Natl Acad Sci U S A (1978) 1.39
Direct evidence for modified solvent structure within the hydration shell of a hydrophobic amino acid. Proc Natl Acad Sci U S A (1996) 1.38
Structural comparison of native and deoxycholate-treated purple membrane. Biophys J (1985) 1.38
An efficient system for the synthesis of bacteriorhodopsin in Halobacterium halobium. Gene (1990) 1.38
Structure of an early intermediate in the M-state phase of the bacteriorhodopsin photocycle. Biophys J (2001) 1.36
Crystal and molecular structure of human annexin V after refinement. Implications for structure, membrane binding and ion channel formation of the annexin family of proteins. J Mol Biol (1992) 1.35
Transient spectroscopy of bacterial rhodopsins with an optical multichannel analyzer. 1. Comparison of the photocycles of bacteriorhodopsin and halorhodopsin. Biochemistry (1989) 1.35
Sodium-stimulated glutamate uptake in membrane vesicles of Escherichia coli: the role of ion gradients. Proc Natl Acad Sci U S A (1977) 1.35
Distortions in the photocycle of bacteriorhodopsin at moderate dehydration. Biophys J (1991) 1.34
Light-induced glutamate transport in Halobacterium halobium envelope vesicles. II. Evidence that the driving force is a light-dependent sodium gradient. Biochemistry (1976) 1.31
Proton transfer from Asp-96 to the bacteriorhodopsin Schiff base is caused by a decrease of the pKa of Asp-96 which follows a protein backbone conformational change. Biochemistry (1993) 1.30
Peptide-chain secondary structure of bacteriorhodopsin. Biophys J (1983) 1.30
Photocycle of halorhodopsin from Halobacterium salinarium. Biophys J (1995) 1.29
pK(a) Calculations suggest storage of an excess proton in a hydrogen-bonded water network in bacteriorhodopsin. J Mol Biol (2001) 1.29
Identification of the retinal-binding protein in halorhodopsin. J Biol Chem (1982) 1.28
Proton transport by halorhodopsin. Biochemistry (1996) 1.28
Relationship of proton release at the extracellular surface to deprotonation of the schiff base in the bacteriorhodopsin photocycle. Biophys J (1995) 1.26
Light-driven chloride ion transport by halorhodopsin from Natronobacterium pharaonis. 1. The photochemical cycle. Biochemistry (1995) 1.26
Lipid interactions in membranes of extremely halophilic bacteria. II. Modification of the bilayer structure by squalene. Biochemistry (1974) 1.25
Estimated acid dissociation constants of the Schiff base, Asp-85, and Arg-82 during the bacteriorhodopsin photocycle. Biophys J (1993) 1.23
Shuttling between two protein conformations: the common mechanism for sensory transduction and ion transport. Curr Opin Cell Biol (1996) 1.23
Light-induced membrane potential and pH gradient in Halobacterium halobium envelope vesicles. Biochemistry (1976) 1.23
Membrane-mediated assembly of annexins studied by site-directed spin labeling. J Biol Chem (1998) 1.23
Proton movements in response to a light-driven electrogenic pump for sodium ions in Halobacterium halobium membranes. J Biol Chem (1979) 1.22
Radiation damage relative to transmission electron microscopy of biological specimens at low temperature: a review. J Microsc (1978) 1.22
Transient channel-opening in bacteriorhodopsin: an EPR study. J Mol Biol (1997) 1.22
Photoreactions of bacteriorhodopsin at acid pH. Biophys J (1989) 1.21
Interaction of aspartate-85 with a water molecule and the protonated Schiff base in the L intermediate of bacteriorhodopsin: a Fourier-transform infrared spectroscopic study. Biochemistry (1994) 1.20
Coupling of aspartate and serine transport to the transmembrane electrochemical gradient for sodium ions in Halobacterium halobium. Translocation stoichiometries and apparent cooperativity. Biochemistry (1978) 1.19
Light-induced glutamate transport in Halobacterium halobium envelope vesicles. I. Kinetics of the light-dependent and the sodium-gradient-dependent uptake. Biochemistry (1976) 1.18
Absorption flattening in the circular dichroism spectra of small membrane fragments. Biochemistry (1985) 1.18
Light-driven chloride ion transport by halorhodopsin from Natronobacterium pharaonis. 2. Chloride release and uptake, protein conformation change, and thermodynamics. Biochemistry (1995) 1.17
Structure of the surface layer protein of the outer membrane of Spirillum serpens. J Ultrastruct Res (1979) 1.17
The back photoreaction of the M intermediate in the photocycle of bacteriorhodopsin: mechanism and evidence for two M species. Photochem Photobiol (1992) 1.16