PubRank

S A Susin

Author PubWeight™ 106.48‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death. Nature 2001 5.07
2 Mitochondrial control of nuclear apoptosis. J Exp Med 1996 5.01
3 Hsp27 negatively regulates cell death by interacting with cytochrome c. Nat Cell Biol 2000 4.89
4 Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J Exp Med 1995 4.88
5 Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. Science 1998 4.84
6 Mitochondrial control of apoptosis. Immunol Today 1997 4.74
7 Chloromethyl-X-Rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis. Cytometry 1996 3.45
8 Heat-shock protein 70 antagonizes apoptosis-inducing factor. Nat Cell Biol 2001 3.05
9 Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis. FASEB J 2000 2.65
10 The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore. J Exp Med 2000 2.62
11 The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins. J Exp Med 1998 2.51
12 Mitochondrial permeability transition is a central coordinating event of apoptosis. J Exp Med 1996 2.39
13 NADH oxidase activity of mitochondrial apoptosis-inducing factor. J Biol Chem 2001 2.22
14 Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death. Cell Death Differ 1999 1.84
15 Apoptosis-inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis. FEBS Lett 2000 1.82
16 Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis. J Immunol 1996 1.64
17 Dominant cell death induction by extramitochondrially targeted apoptosis-inducing factor. FASEB J 2001 1.64
18 Bcl-2 down-regulation causes autophagy in a caspase-independent manner in human leukemic HL60 cells. Cell Death Differ 2000 1.64
19 Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: role of mitochondria and caspases. J Exp Med 2000 1.59
20 Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis. FEBS Lett 1996 1.58
21 The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death. Oncogene 1997 1.53
22 Mitochondria and programmed cell death: back to the future. FEBS Lett 1996 1.52
23 Cytofluorometric detection of mitochondrial alterations in early CD95/Fas/APO-1-triggered apoptosis of Jurkat T lymphoma cells. Comparison of seven mitochondrion-specific fluorochromes. Immunol Lett 1998 1.51
24 Disruption of the outer mitochondrial membrane as a result of large amplitude swelling: the impact of irreversible permeability transition. FEBS Lett 1998 1.49
25 Programmed cell death via mitochondria: different modes of dying. Biochemistry (Mosc) 2005 1.48
26 Subcellular and submitochondrial mode of action of Bcl-2-like oncoproteins. Oncogene 1998 1.47
27 Oxidation of a critical thiol residue of the adenine nucleotide translocator enforces Bcl-2-independent permeability transition pore opening and apoptosis. Oncogene 2000 1.45
28 Activation of mitochondria and release of mitochondrial apoptogenic factors by betulinic acid. J Biol Chem 1998 1.41
29 Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore. Exp Cell Res 1999 1.33
30 Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis. Oncogene 2001 1.32
31 Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus. J Infect Dis 2001 1.30
32 Nitric oxide induces apoptosis via triggering mitochondrial permeability transition. FEBS Lett 1997 1.30
33 Relocalization of apoptosis-inducing factor in photoreceptor apoptosis induced by retinal detachment in vivo. Am J Pathol 2001 1.29
34 Lonidamine triggers apoptosis via a direct, Bcl-2-inhibited effect on the mitochondrial permeability transition pore. Oncogene 1999 1.26
35 GD3 ganglioside directly targets mitochondria in a bcl-2-controlled fashion. FASEB J 2000 1.24
36 Mitochondrial membrane permeabilization during the apoptotic process. Ann N Y Acad Sci 1999 1.24
37 Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA. Cancer Res 1996 1.24
38 PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection. Exp Cell Res 1998 1.23
39 Cysteine protease inhibition prevents mitochondrial apoptosis-inducing factor (AIF) release. Cell Death Differ 2005 1.20
40 Caspases disrupt mitochondrial membrane barrier function. FEBS Lett 1998 1.19
41 Mitochondrial permeability transition triggers lymphocyte apoptosis. J Immunol 1996 1.19
42 BID regulates AIF-mediated caspase-independent necroptosis by promoting BAX activation. Cell Death Differ 2011 1.18
43 Mass spectrometric identification of proteins released from mitochondria undergoing permeability transition. Cell Death Differ 2000 1.15
44 Mitochondrial permeability transition in apoptosis and necrosis. Cell Biol Toxicol 1998 1.11
45 Potassium leakage during the apoptotic degradation phase. J Immunol 1998 1.09
46 The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition. Oncogene 1998 1.09
47 Glutathione depletion is an early and calcium elevation is a late event of thymocyte apoptosis. J Immunol 1997 1.08
48 HIV induces lymphocyte apoptosis by a p53-initiated, mitochondrial-mediated mechanism. FASEB J 2000 1.08
49 Redox regulation of apoptosis: impact of thiol oxidation status on mitochondrial function. Eur J Immunol 1997 1.07
50 Molecular ordering of apoptosis induced by anticancer drugs in neuroblastoma cells. Cancer Res 1998 1.06
51 AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation. Cell Death Dis 2012 0.97
52 Palmitate induces apoptosis via a direct effect on mitochondria. Apoptosis 1999 0.95
53 CD44 ligation induces caspase-independent cell death via a novel calpain/AIF pathway in human erythroleukemia cells. Oncogene 2006 0.94
54 Caspase-independent commitment phase to apoptosis in activated blood T lymphocytes: reversibility at low apoptotic insult. Blood 2000 0.92
55 Proteasome activation occurs at an early, premitochondrial step of thymocyte apoptosis. J Immunol 1998 0.90
56 Simplification of complex peptide mixtures for proteomic analysis: reversible biotinylation of cysteinyl peptides. Electrophoresis 2000 0.88
57 The novel retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid can trigger apoptosis through a mitochondrial pathway independent of the nucleus. Cancer Res 1999 0.87
58 Regulation of apoptosis/necrosis execution in cadmium-treated human promonocytic cells under different forms of oxidative stress. Apoptosis 2006 0.87
59 Pre-processed caspase-9 contained in mitochondria participates in apoptosis. Cell Death Differ 2002 0.85
60 Functional assessment of p53 in chronic lymphocytic leukemia. Blood Cancer J 2011 0.85
61 Caspase-independent type III PCD: a new means to modulate cell death in chronic lymphocytic leukemia. Leukemia 2008 0.81
62 Involvement of apoptosis-inducing factor during dolichyl monophosphate-induced apoptosis in U937 cells. FEBS Lett 2000 0.77
63 GD3 ganglioside as an intracellular mediator of apoptosis. Eur Cytokine Netw 2000 0.75
64 Cytofluorometric quantitation of nuclear apoptosis induced in a cell-free system. Methods Enzymol 2000 0.75