Mitochondrial abnormalities in ageing macular photoreceptors.

PubWeight™: 1.25‹?› | Rank: Top 10%

🔗 View Article (PMID 11687550)

Published in Invest Ophthalmol Vis Sci on November 01, 2001

Authors

M J Barron1, M A Johnson, R M Andrews, M P Clarke, P G Griffiths, E Bristow, L P He, S Durham, D M Turnbull

Author Affiliations

1: School of Neurosciences and Psychiatry, University of Newcastle-upon-Tyne, UK.

Articles citing this

A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration. Proc Natl Acad Sci U S A (2007) 3.50

Molecular pathology of age-related macular degeneration. Prog Retin Eye Res (2008) 3.35

Understanding age-related macular degeneration (AMD): relationships between the photoreceptor/retinal pigment epithelium/Bruch's membrane/choriocapillaris complex. Mol Aspects Med (2012) 2.37

Therapeutic photobiomodulation for methanol-induced retinal toxicity. Proc Natl Acad Sci U S A (2003) 1.88

The age lipid A2E and mitochondrial dysfunction synergistically impair phagocytosis by retinal pigment epithelial cells. J Biol Chem (2008) 1.61

Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration. Autophagy (2013) 1.34

Mitochondrial proteomics of the retinal pigment epithelium at progressive stages of age-related macular degeneration. Invest Ophthalmol Vis Sci (2008) 1.31

Increased mitochondrial DNA damage and down-regulation of DNA repair enzymes in aged rodent retinal pigment epithelium and choroid. Mol Vis (2008) 1.31

Aging is not a disease: distinguishing age-related macular degeneration from aging. Prog Retin Eye Res (2013) 1.29

Mitochondrial DNA damage as a potential mechanism for age-related macular degeneration. Invest Ophthalmol Vis Sci (2010) 1.28

SOD2 protects against oxidation-induced apoptosis in mouse retinal pigment epithelium: implications for age-related macular degeneration. Invest Ophthalmol Vis Sci (2005) 1.22

LOC387715/HTRA1 gene polymorphisms and susceptibility to age-related macular degeneration: A HuGE review and meta-analysis. Mol Vis (2010) 1.11

Genetic mechanisms and age-related macular degeneration: common variants, rare variants, copy number variations, epigenetics, and mitochondrial genetics. Hum Genomics (2012) 0.90

Somatic mitochondrial DNA deletions accumulate to high levels in aging human extraocular muscles. Invest Ophthalmol Vis Sci (2010) 0.88

Next-generation sequencing of mitochondrial targeted AAV transfer of human ND4 in mice. Mol Vis (2013) 0.81

Cumulative mtDNA damage and mutations contribute to the progressive loss of RGCs in a rat model of glaucoma. Neurobiol Dis (2014) 0.80

Retinal Remodeling and Metabolic Alterations in Human AMD. Front Cell Neurosci (2016) 0.78

Review: adiponectin in retinopathy. Biochim Biophys Acta (2016) 0.78

Using current data to define new approach in age related macular degeneration: need to accelerate translational research. Curr Genomics (2014) 0.77

Photobiomodulation for the treatment of retinal diseases: a review. Int J Ophthalmol (2016) 0.76

Imaging drusens using Spectral Domain Optical Coherence Tomography. Saudi J Ophthalmol (2015) 0.75

FGF21 Administration Suppresses Retinal and Choroidal Neovascularization in Mice. Cell Rep (2017) 0.75

Adiponectin Mediates Dietary Omega-3 Long-Chain Polyunsaturated Fatty Acid Protection Against Choroidal Neovascularization in Mice. Invest Ophthalmol Vis Sci (2017) 0.75

Articles by these authors

Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA. Nat Genet (1999) 18.22

Data on the distribution of fibre types in thirty-six human muscles. An autopsy study. J Neurol Sci (1973) 6.62

Comparison of first-line antiretroviral therapy with regimens including nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: a randomised open-label trial, the 2NN Study. Lancet (2004) 6.27

Multi-system neurological disease is common in patients with OPA1 mutations. Brain (2010) 5.37

A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome. Nat Genet (2001) 5.34

The implications of using an inappropriate reference gene for real-time reverse transcription PCR data normalization. Anal Biochem (2005) 4.94

Vigabatrin-associated retinal cone system dysfunction: electroretinogram and ophthalmologic findings. Neurology (1998) 4.01

Very mild muscular dystrophy associated with the deletion of 46% of dystrophin. Nature (1990) 3.84

Paradoxical reactions during tuberculosis treatment in patients with and without HIV co-infection. Thorax (2004) 3.77

Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma. Am Rev Respir Dis (1990) 3.70

Sulphasalazine in rheumatoid arthritis. Br Med J (1980) 3.53

The polymerase chain reaction: a new epidemiological tool for investigating cervical human papillomavirus infection. BMJ (1989) 3.43

Growth, survival, and resistance of the Legionnaires' disease bacterium. Ann Intern Med (1979) 3.36

S-nitrosothiols signal the ventilatory response to hypoxia. Nature (2001) 3.26

Open access clinic providing HIV-I antibody results on day of testing: the first twelve months. BMJ (1991) 3.17

Vaccines for preventing pneumococcal infection in adults. Cochrane Database Syst Rev (2008) 3.13

Assaying mitochondrial respiratory complex activity in mitochondria isolated from human cells and tissues. Methods Cell Biol (2001) 3.00

Staging system for clinical AIDS patients. Royal Free/Chelsea and Westminster Hospitals Collaborative Group. Lancet (1995) 2.90

Allergen injection immunotherapy for seasonal allergic rhinitis. Cochrane Database Syst Rev (2007) 2.77

Leber hereditary optic neuropathy: identification of the same mitochondrial ND1 mutation in six pedigrees. Am J Hum Genet (1991) 2.70

The epidemiology of Leber hereditary optic neuropathy in the North East of England. Am J Hum Genet (2002) 2.67

Inherited mitochondrial optic neuropathies. J Med Genet (2008) 2.50

A single amino acid substitution in the V1 loop of human immunodeficiency virus type 1 gp120 alters cellular tropism. J Virol (1993) 2.46

Mammalian mitochondrial genetics: heredity, heteroplasmy and disease. Trends Genet (1997) 2.45

Theophylline prescribing, serum concentrations, and toxicity. Lancet (1983) 2.40

Leber hereditary optic neuropathy. J Med Genet (2002) 2.33

Random intracellular drift explains the clonal expansion of mitochondrial DNA mutations with age. Am J Hum Genet (2001) 2.31

Laboratory control values for CD4 and CD8 T lymphocytes. Implications for HIV-1 diagnosis. Clin Exp Immunol (1992) 2.27

Somatic mitochondrial DNA mutations in adult-onset leukaemia. Leukemia (2003) 2.26

The pedigree rate of sequence divergence in the human mitochondrial genome: there is a difference between phylogenetic and pedigree rates. Am J Hum Genet (2003) 2.23

Factors affecting survival in patients with the acquired immunodeficiency syndrome. AIDS (1996) 2.22

The epidemiology of pathogenic mitochondrial DNA mutations. Ann Neurol (2000) 2.20

The inheritance of mitochondrial DNA heteroplasmy: random drift, selection or both? Trends Genet (2000) 2.19

Loss of mucosal CD4 lymphocytes is an early feature of HIV infection. Clin Exp Immunol (1993) 2.17

The determination of complete human mitochondrial DNA sequences in single cells: implications for the study of somatic mitochondrial DNA point mutations. Nucleic Acids Res (2001) 2.17

Bias due to incomplete follow up in a cohort study. Br J Ophthalmol (1999) 2.15

Automated perimetry by optometrists in patients at low risk of glaucoma. Br J Ophthalmol (1998) 2.11

Molecular pathology of MELAS and MERRF. The relationship between mutation load and clinical phenotypes. Brain (1997) 2.09

Virological response to highly active antiretroviral therapy is unaffected by antituberculosis therapy. J Infect Dis (2006) 2.09

Role of mitochondrial DNA mutations in human aging: implications for the central nervous system and muscle. Ann Neurol (1998) 2.08

Transmission of mitochondrial DNA disorders: possibilities for the future. Lancet (2006) 2.05

An alternative to "brutacaine": a comparison of low dose intramuscular ketamine with intranasal midazolam in children before suturing. J Accid Emerg Med (1998) 2.03

The Newcastle Control Score: a new method of grading the severity of intermittent distance exotropia. Br J Ophthalmol (2004) 2.02

Autosomal recessive mitochondrial ataxic syndrome due to mitochondrial polymerase gamma mutations. Neurology (2005) 2.01

Epidemiology of cerebral palsy in England and Scotland, 1984-9. Arch Dis Child Fetal Neonatal Ed (1998) 2.01

Impaired cerebral vasoreactivity after embolization of arteriovenous malformations: assessment with serial acetazolamide challenge xenon CT. AJNR Am J Neuroradiol (1991) 1.96

Lymphocyte activation in HIV-1 infection. II. Functional defects of CD28- T cells. AIDS (1994) 1.93

Random genetic drift determines the level of mutant mtDNA in human primary oocytes. Am J Hum Genet (2000) 1.89

Methods of microphotometric assay of succinate dehydrogenase and cytochrome c oxidase activities for use on human skeletal muscle. Histochem J (1990) 1.89

Mitochondrial disease in adults: a scale to monitor progression and treatment. Neurology (2006) 1.87

Reasons for modification and discontinuation of antiretrovirals: results from a single treatment centre. AIDS (2001) 1.86

Tenofovir-associated renal and bone toxicity. HIV Med (2009) 1.82

Clinical features, diagnosis and management of maternally inherited diabetes and deafness (MIDD) associated with the 3243A>G mitochondrial point mutation. Diabet Med (2008) 1.82

Comparative genomics and the evolution of human mitochondrial DNA: assessing the effects of selection. Am J Hum Genet (2004) 1.80

Mitochondrial gene segregation in mammals: is the bottleneck always narrow? Hum Genet (1992) 1.77

Flashes and floaters as predictors of vitreoretinal pathology: is follow-up necessary for posterior vitreous detachment? Eye (Lond) (1996) 1.77

Safety and efficacy of lamivudine-zidovudine combination therapy in zidovudine-experienced patients. A randomized controlled comparison with zidovudine monotherapy. Lamivudine European HIV Working Group. JAMA (1996) 1.77

Peptide nucleic acid delivery to human mitochondria. Gene Ther (1999) 1.77

MELAS associated with mutations in the POLG1 gene. Neurology (2007) 1.77

HHV-6 in AIDS. Lancet (1994) 1.76

An evaluation of the measurement of the activities of complexes I-IV in the respiratory chain of human skeletal muscle mitochondria. Biochem Med Metab Biol (1994) 1.74

Enhanced measles surveillance during an interepidemic period in Victoria. Med J Aust (2000) 1.73

GA(2)LEN skin test study I: GA(2)LEN harmonization of skin prick testing: novel sensitization patterns for inhalant allergens in Europe. Allergy (2009) 1.72

Infrared signature of structures associated with the H+(H2O)n (n = 6 to 27) clusters. Science (2004) 1.71

Dysferlin is a plasma membrane protein and is expressed early in human development. Hum Mol Genet (1999) 1.69

The ocular manifestations of the Sturge-Weber syndrome. J Pediatr Ophthalmol Strabismus (1993) 1.69

Preschool vision screening: a prospective comparative evaluation. Eye (Lond) (1996) 1.68

Cytomegalovirus (CMV) viraemia detected by polymerase chain reaction identifies a group of HIV-positive patients at high risk of CMV disease. AIDS (1997) 1.68

Biochemical and molecular studies of mitochondrial function in diabetes insipidus, diabetes mellitus, optic atrophy, and deafness. Diabetes Care (1994) 1.68

Biochemistry of Oleoresinosis : Monoterpene and Diterpene Biosynthesis in Lodgepole Pine Saplings Infected with Ceratocystis clavigera or Treated with Carbohydrate Elicitors. Plant Physiol (1987) 1.68

A new mtDNA mutation showing accumulation with time and restriction to skeletal muscle. Am J Hum Genet (1997) 1.68

Pharmacokinetics and antiretroviral activity of lamivudine alone or when coadministered with zidovudine in human immunodeficiency virus type 1-infected pregnant women and their offspring. J Infect Dis (1998) 1.67

ICD-10 codes are a valid tool for identification of pneumonia in hospitalized patients aged > or = 65 years. Epidemiol Infect (2007) 1.67

Further observations on the pathological responses of rat skeletal muscle to toxins isolated from the venom of the Australian tiger snake, Notechis scutatus scutatus. Clin Exp Pharmacol Physiol (1979) 1.66

Rapid decline in detectability of HIV-1 drug resistance mutations after stopping therapy. AIDS (1999) 1.65

Increased numbers of primed activated CD8+CD38+CD45RO+ T cells predict the decline of CD4+ T cells in HIV-1-infected patients. AIDS (1996) 1.64

Mitochondrial disease--its impact, etiology, and pathology. Curr Top Dev Biol (2007) 1.64

Effectiveness of testing visual fields by confrontation. Lancet (2001) 1.64

Disintegration/dissolution profiles of copies of Fosamax (alendronate). Curr Med Res Opin (2003) 1.62

Branhamella (Neisseria) catarrhalis--a lower respiratory tract pathogen? J Clin Microbiol (1981) 1.61

Adverse events and treatment interruption in tuberculosis patients with and without HIV co-infection. Thorax (2006) 1.60

Mitochondrial medicine. QJM (1997) 1.58

Refractive errors in children born before 32 weeks gestation. Eye (Lond) (1997) 1.56

Relationship between herpes simplex virus ulceration and CD4+ cell counts in patients with HIV infection. AIDS (1992) 1.56

Assessment of airway inflammation: an overview. Eur Respir J Suppl (1998) 1.55

Selective inhibition of mutant human mitochondrial DNA replication in vitro by peptide nucleic acids. Nat Genet (1997) 1.53

Biosynthesis of monoterpenes: partial purification, characterization, and mechanism of action of 1,8-cineole synthase. Arch Biochem Biophys (1994) 1.53

Data on fibre size in thirty-six human muscles. An autopsy study. J Neurol Sci (1973) 1.53

Heterogeneity of dystrophin expression in patients with Duchenne and Becker muscular dystrophy. Acta Neuropathol (1990) 1.52

Early diagnosis of HIV infection. Br J Hosp Med (1990) 1.51

Analysis of European mtDNAs for recombination. Am J Hum Genet (2000) 1.51