Published in Proc Natl Acad Sci U S A on September 20, 2007
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Mitochondrial DNA variants of respiratory complex I that uniquely characterize haplogroup T2 are associated with increased risk of age-related macular degeneration. PLoS One (2009) 1.19
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A randomized pilot study of systemic immunosuppression in the treatment of age-related macular degeneration with choroidal neovascularization. Retina (2010) 1.14
Mechanism of inflammation in age-related macular degeneration. Mediators Inflamm (2012) 1.14
The importance of mitochondria in age-related and inherited eye disorders. Ophthalmic Res (2010) 1.13
LOC387715/HTRA1 gene polymorphisms and susceptibility to age-related macular degeneration: A HuGE review and meta-analysis. Mol Vis (2010) 1.11
Sequence variants in HTRA1 and LOC387715/ARMS2 and phenotype and response to photodynamic therapy in neovascular age-related macular degeneration in populations from Israel. Mol Vis (2008) 1.10
Dietary omega-3 fatty acids, other fat intake, genetic susceptibility, and progression to incident geographic atrophy. Ophthalmology (2013) 1.08
Identification of novel substrates for the serine protease HTRA1 in the human RPE secretome. Invest Ophthalmol Vis Sci (2010) 1.08
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The HtrA1 promoter polymorphism, smoking, and age-related macular degeneration in multiple case-control samples. Ophthalmology (2008) 1.07
Localization of age-related macular degeneration-associated ARMS2 in cytosol, not mitochondria. Invest Ophthalmol Vis Sci (2009) 1.07
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Analysis of the indel at the ARMS2 3'UTR in age-related macular degeneration. Hum Genet (2010) 1.04
Multifactor effects and evidence of potential interaction between complement factor H Y402H and LOC387715 A69S in age-related macular degeneration. PLoS One (2008) 1.03
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Joint effects of polymorphisms in the HTRA1, LOC387715/ARMS2, and CFH genes on AMD in a Caucasian population. Mol Vis (2008) 0.99
Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration. J Biol Chem (2012) 0.99
Age-related retinal degeneration (arrd2) in a novel mouse model due to a nonsense mutation in the Mdm1 gene. Hum Mol Genet (2008) 0.99
Age-related macular degeneration-associated variants at chromosome 10q26 do not significantly alter ARMS2 and HTRA1 transcript levels in the human retina. Mol Vis (2010) 0.98
CFH, VEGF, and PEDF genotypes and the response to intravitreous injection of bevacizumab for the treatment of age-related macular degeneration. J Ocul Biol Dis Infor (2010) 0.98
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A genome-wide association study for primary open angle glaucoma and macular degeneration reveals novel Loci. PLoS One (2013) 0.97
Nutritional modulation of age-related macular degeneration. Mol Aspects Med (2012) 0.97
Mitochondrial DNA variants mediate energy production and expression levels for CFH, C3 and EFEMP1 genes: implications for age-related macular degeneration. PLoS One (2013) 0.96
Changes in retinal pigment epithelium related to cigarette smoke: possible relevance to smoking as a risk factor for age-related macular degeneration. PLoS One (2009) 0.96
Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: a systems biology based approach. Vision Res (2009) 0.95
Evaluation of clustering and genotype distribution for replication in genome wide association studies: the age-related eye disease study. PLoS One (2008) 0.95
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C-reactive protein and CFH, ARMS2/HTRA1 gene variants are independently associated with risk of macular degeneration. Ophthalmology (2010) 0.92
Mechanism of inflammation in age-related macular degeneration: an up-to-date on genetic landmarks. Mediators Inflamm (2013) 0.91
Mitochondrial DNA haplogroups confer differences in risk for age-related macular degeneration: a case control study. BMC Med Genet (2013) 0.91
Genetic and functional dissection of ARMS2 in age-related macular degeneration and polypoidal choroidal vasculopathy. PLoS One (2013) 0.90
Association of CFH, LOC387715, and HTRA1 polymorphisms with exudative age-related macular degeneration in a northern Chinese population. Mol Vis (2008) 0.90
Positive association of common variants in CD36 with neovascular age-related macular degeneration. Aging (Albany NY) (2009) 0.89
Functional effect of Saffron supplementation and risk genotypes in early age-related macular degeneration: a preliminary report. J Transl Med (2013) 0.89
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Biologically active fibronectin fragments stimulate release of MCP-1 and catabolic cytokines from murine retinal pigment epithelium. Invest Ophthalmol Vis Sci (2009) 0.88
Cell-deposited matrix improves retinal pigment epithelium survival on aged submacular human Bruch's membrane. Invest Ophthalmol Vis Sci (2011) 0.87
Haplotype analysis of the ARMS2/HTRA1 region in Japanese patients with typical neovascular age-related macular degeneration or polypoidal choroidal vasculopathy. Jpn J Ophthalmol (2010) 0.87
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Interaction of complement factor h and fibulin3 in age-related macular degeneration. PLoS One (2013) 0.86
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Influence of ROBO1 and RORA on risk of age-related macular degeneration reveals genetically distinct phenotypes in disease pathophysiology. PLoS One (2011) 0.85
Risk factors and biomarkers of age-related macular degeneration. Prog Retin Eye Res (2016) 0.85
The ARMS2 A69S variant and bilateral advanced age-related macular degeneration. Retina (2012) 0.83
Advanced glycation endproduct changes to Bruch's membrane promotes lipoprotein retention by lipoprotein lipase. Am J Pathol (2011) 0.83
Update on the role of genetics in the onset of age-related macular degeneration. Clin Ophthalmol (2011) 0.83
Association of HTRA1 promoter polymorphism with spinal disc degeneration in Japanese women. J Bone Miner Metab (2009) 0.82
Comparison of drusen and modifying genes in autosomal dominant radial drusen and age-related macular degeneration. Retina (2015) 0.82
Association of ARMS2/HTRA1 variants with polypoidal choroidal vasculopathy phenotype in a Korean population. Jpn J Ophthalmol (2011) 0.82
Association of LIPC and advanced age-related macular degeneration. Eye (Lond) (2013) 0.81
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Cumulative association between age-related macular degeneration and less studied genetic variants in PLEKHA1/ARMS2/HTRA1: a meta and gene-cluster analysis. Mol Biol Rep (2013) 0.81
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