PubRank

Caroline Kisker

Author PubWeight™ 71.68‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis. EMBO J 2003 2.69
2 High affinity InhA inhibitors with activity against drug-resistant strains of Mycobacterium tuberculosis. ACS Chem Biol 2006 2.50
3 Prokaryotic nucleotide excision repair: the UvrABC system. Chem Rev 2006 2.37
4 The crystal structure of plant sulfite oxidase provides insights into sulfite oxidation in plants and animals. Structure 2003 2.15
5 Constitutive activation of PKA catalytic subunit in adrenal Cushing's syndrome. N Engl J Med 2014 1.89
6 Functional human mitochondrial DNA polymerase gamma forms a heterotrimer. J Biol Chem 2005 1.85
7 Lesion (in)tolerance reveals insights into DNA replication fidelity. EMBO J 2004 1.83
8 Crystal structure of the FeS cluster-containing nucleotide excision repair helicase XPD. PLoS Biol 2008 1.81
9 Slow-onset inhibition of the FabI enoyl reductase from francisella tularensis: residence time and in vivo activity. ACS Chem Biol 2009 1.53
10 Structural basis for DNA recognition and processing by UvrB. Nat Struct Mol Biol 2006 1.51
11 Crystal structures of Mycobacterium tuberculosis KasA show mode of action within cell wall biosynthesis and its inhibition by thiolactomycin. Structure 2009 1.50
12 DNA binding cooperativity of p53 modulates the decision between cell-cycle arrest and apoptosis. Mol Cell 2010 1.47
13 The beta -hairpin motif of UvrB is essential for DNA binding, damage processing, and UvrC-mediated incisions. J Biol Chem 2001 1.46
14 A slow, tight binding inhibitor of InhA, the enoyl-acyl carrier protein reductase from Mycobacterium tuberculosis. J Biol Chem 2010 1.41
15 'Close-fitting sleeves': DNA damage recognition by the UvrABC nuclease system. Mutat Res 2005 1.39
16 Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis. J Biol Chem 2003 1.37
17 Crystal structures of the active and alloxanthine-inhibited forms of xanthine dehydrogenase from Rhodobacter capsulatus. Structure 2002 1.35
18 Structural insights into the first incision reaction during nucleotide excision repair. EMBO J 2005 1.30
19 Functional and structural studies of the nucleotide excision repair helicase XPD suggest a polarity for DNA translocation. EMBO J 2011 1.28
20 Staphylococcus aureus FabI: inhibition, substrate recognition, and potential implications for in vivo essentiality. Structure 2012 1.22
21 Structural insights into sulfite oxidase deficiency. J Biol Chem 2005 1.21
22 Interactions between UvrA and UvrB: the role of UvrB's domain 2 in nucleotide excision repair. EMBO J 2004 1.15
23 Structural basis of assembly chaperone- mediated snRNP formation. Mol Cell 2013 1.13
24 Lysine 190 is the catalytic base in MenF, the menaquinone-specific isochorismate synthase from Escherichia coli: implications for an enzyme family. Biochemistry 2007 1.10
25 Structure of the C-terminal half of UvrC reveals an RNase H endonuclease domain with an Argonaute-like catalytic triad. EMBO J 2007 1.09
26 Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis. Biochemistry 2007 1.08
27 Rational optimization of drug-target residence time: insights from inhibitor binding to the Staphylococcus aureus FabI enzyme-product complex. Biochemistry 2013 1.05
28 Characterizing septum inhibition in Mycobacterium tuberculosis for novel drug discovery. Tuberculosis (Edinb) 2008 1.04
29 Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways. J Biol Chem 2006 1.01
30 Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability. J Biol Chem 2013 0.99
31 Novel somatic mutations in the catalytic subunit of the protein kinase A as a cause of adrenal Cushing's syndrome: a European multicentric study. J Clin Endocrinol Metab 2014 0.97
32 Identification of residues within UvrB that are important for efficient DNA binding and damage processing. J Biol Chem 2004 0.92
33 Mechanism of Substrate and Inhibitor Binding of Rhodobacter capsulatus Xanthine Dehydrogenase. J Biol Chem 2008 0.91
34 Slow onset inhibition of bacterial beta-ketoacyl-acyl carrier protein synthases by thiolactomycin. J Biol Chem 2009 0.91
35 Development of modern InhA inhibitors to combat drug resistant strains of Mycobacterium tuberculosis. Curr Top Med Chem 2007 0.91
36 The EM structure of human DNA polymerase gamma reveals a localized contact between the catalytic and accessory subunits. EMBO J 2007 0.90
37 Isolated sulfite oxidase deficiency: identification of 12 novel SUOX mutations in 10 patients. Hum Mutat 2002 0.90
38 Damage recognition in nucleotide excision DNA repair. Curr Opin Struct Biol 2012 0.90
39 Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors with unusual amino acids. J Med Chem 2010 0.89
40 Strand-specific recognition of DNA damages by XPD provides insights into nucleotide excision repair substrate versatility. J Biol Chem 2013 0.88
41 The XPD helicase: XPanDing archaeal XPD structures to get a grip on human DNA repair. Biol Chem 2010 0.88
42 Mechanism of the intramolecular Claisen condensation reaction catalyzed by MenB, a crotonase superfamily member. Biochemistry 2011 0.86
43 The Q motif of Fanconi anemia group J protein (FANCJ) DNA helicase regulates its dimerization, DNA binding, and DNA repair function. J Biol Chem 2012 0.86
44 Biophysical and functional analyses suggest that adenovirus E4-ORF3 protein requires higher-order multimerization to function against promyelocytic leukemia protein nuclear bodies. J Biol Chem 2012 0.85
45 Raf kinase inhibitor protein (RKIP) dimer formation controls its target switch from Raf1 to G protein-coupled receptor kinase (GRK) 2. J Biol Chem 2012 0.85
46 Structural analysis of missense mutations causing isolated sulfite oxidase deficiency. Dalton Trans 2005 0.84
47 Stereoselectivity of enoyl-CoA hydratase results from preferential activation of one of two bound substrate conformers. Chem Biol 2002 0.84
48 The 1.2 A structure of the human sulfite oxidase cytochrome b(5) domain. Acta Crystallogr D Biol Crystallogr 2003 0.84
49 The structures of the C185S and C185A mutants of sulfite oxidase reveal rearrangement of the active site. Biochemistry 2010 0.83
50 DNA Helicases in NER, BER, and MMR. Adv Exp Med Biol 2013 0.82
51 XPB helicase regulates DNA incision by the Thermoplasma acidophilum endonuclease Bax1. DNA Repair (Amst) 2012 0.82
52 Bax1 is a novel endonuclease: implications for archaeal nucleotide excision repair. J Biol Chem 2009 0.79
53 Structural basis for the recognition of mycolic acid precursors by KasA, a condensing enzyme and drug target from Mycobacterium tuberculosis. J Biol Chem 2013 0.79
54 Structure of the Yersinia pestis FabV enoyl-ACP reductase and its interaction with two 2-pyridone inhibitors. Structure 2012 0.78
55 Crystallographic characterization of an exocyclic DNA adduct: 3,N4-etheno-2'-deoxycytidine in the dodecamer 5'-CGCGAATTepsilonCGCG-3'. J Mol Biol 2003 0.78
56 DNA damage, mutagenesis, and DNA repair. J Nucleic Acids 2010 0.77
57 Molecular dynamics of Mycobacterium tuberculosis KasA: implications for inhibitor and substrate binding and consequences for drug design. J Comput Aided Mol Des 2011 0.76
58 On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences. J Med Chem 2009 0.76
59 Elucidation of the protonation states of the catalytic residues in mtKasA: implications for inhibitor design. Biochemistry 2011 0.76
60 Transcriptional pausing to scout ahead for DNA damage. Proc Natl Acad Sci U S A 2014 0.76
61 When one protein does the job of many. Structure 2007 0.75
62 [Old and new anti-mycobacterial drugs. Fatty acid synthesis as a target]. Pharm Unserer Zeit 2012 0.75