Published in J Biol Chem on October 30, 2001
Crystal structure of the FeS cluster-containing nucleotide excision repair helicase XPD. PLoS Biol (2008) 1.81
TFIIH: when transcription met DNA repair. Nat Rev Mol Cell Biol (2012) 1.63
The presence of two UvrB subunits in the UvrAB complex ensures damage detection in both DNA strands. EMBO J (2002) 1.32
Incision of DNA-protein crosslinks by UvrABC nuclease suggests a potential repair pathway involving nucleotide excision repair. Proc Natl Acad Sci U S A (2002) 1.31
Structural insights into the first incision reaction during nucleotide excision repair. EMBO J (2005) 1.30
Homologous recombination but not nucleotide excision repair plays a pivotal role in tolerance of DNA-protein cross-links in mammalian cells. J Biol Chem (2009) 1.29
Prokaryotic nucleotide excision repair. Cold Spring Harb Perspect Biol (2013) 1.16
Recognition and incision of gamma-radiation-induced cross-linked guanine-thymine tandem lesion G[8,5-Me]T by UvrABC nuclease. Chem Res Toxicol (2005) 1.15
Interactions between UvrA and UvrB: the role of UvrB's domain 2 in nucleotide excision repair. EMBO J (2004) 1.15
The C-terminal zinc finger of UvrA does not bind DNA directly but regulates damage-specific DNA binding. J Biol Chem (2006) 1.10
Functional characterization and atomic force microscopy of a DNA repair protein conjugated to a quantum dot. Nano Lett (2008) 1.09
Repair activity of base and nucleotide excision repair enzymes for guanine lesions induced by nitrosative stress. Nucleic Acids Res (2005) 1.06
Reverse gyrase has heat-protective DNA chaperone activity independent of supercoiling. Nucleic Acids Res (2004) 1.05
Strand- and site-specific DNA lesion demarcation by the xeroderma pigmentosum group D helicase. Proc Natl Acad Sci U S A (2010) 1.05
DNA tandem lesion repair by strand displacement synthesis and nucleotide excision repair. Biochemistry (2008) 1.03
A cut above: discovery of an alternative excision repair pathway in bacteria. Proc Natl Acad Sci U S A (2002) 0.99
Stimulation of UvrD helicase by UvrAB. J Biol Chem (2009) 0.99
Removal of misincorporated ribonucleotides from prokaryotic genomes: an unexpected role for nucleotide excision repair. PLoS Genet (2013) 0.98
Nucleotide excision repair of a DNA interstrand cross-link produces single- and double-strand breaks. Biochemistry (2010) 0.97
NMR analysis of [methyl-13C]methionine UvrB from Bacillus caldotenax reveals UvrB-domain 4 heterodimer formation in solution. J Mol Biol (2007) 0.95
Oxidative stress resistance in Porphyromonas gingivalis. Future Microbiol (2012) 0.95
Dynamics of lesion processing by bacterial nucleotide excision repair proteins. Prog Mol Biol Transl Sci (2012) 0.93
DNA damage recognition of mutated forms of UvrB proteins in nucleotide excision repair. Biochemistry (2004) 0.92
Cooperative damage recognition by UvrA and UvrB: identification of UvrA residues that mediate DNA binding. DNA Repair (Amst) (2008) 0.91
DNA wrapping is required for DNA damage recognition in the Escherichia coli DNA nucleotide excision repair pathway. Proc Natl Acad Sci U S A (2009) 0.89
Real-time single-molecule imaging reveals a direct interaction between UvrC and UvrB on DNA tightropes. Nucleic Acids Res (2013) 0.88
Efficient processing of TFO-directed psoralen DNA interstrand crosslinks by the UvrABC nuclease. Nucleic Acids Res (2008) 0.88
Repair of hydantoin lesions and their amine adducts in DNA by base and nucleotide excision repair. J Am Chem Soc (2013) 0.87
DNA repair of 8-oxo-7,8-dihydroguanine lesions in Porphyromonas gingivalis. J Bacteriol (2008) 0.87
Robust incision of Benoz[a]pyrene-7,8-dihyrodiol-9,10-epoxide-DNA adducts by a recombinant thermoresistant interspecies combination UvrABC endonuclease system. Biochemistry (2006) 0.84
Single-molecule analysis reveals two separate DNA-binding domains in the Escherichia coli UvrA dimer. Nucleic Acids Res (2009) 0.84
Interplay of DNA repair with transcription: from structures to mechanisms. Trends Biochem Sci (2012) 0.80
Ribonucleotides as nucleotide excision repair substrates. DNA Repair (Amst) (2013) 0.79
Nucleotide excision repair of chemically stabilized analogues of DNA interstrand cross-links produced from oxidized abasic sites. Biochemistry (2014) 0.78
Investigation of bacterial nucleotide excision repair using single-molecule techniques. DNA Repair (Amst) (2014) 0.76
Repair of the major lesion resulting from C5'-oxidation of DNA. Biochemistry (2011) 0.75
A tale of two cities: A tribute to Aziz Sancar's Nobel Prize in Chemistry for his molecular characterization of NER. DNA Repair (Amst) (2016) 0.75
Standardizing global gene expression analysis between laboratories and across platforms. Nat Methods (2005) 6.23
Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells. Methods Mol Biol (2006) 2.87
Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis. EMBO J (2003) 2.69
Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro. Mol Cell Biol (2004) 2.65
Energy metabolism in human pluripotent stem cells and their differentiated counterparts. PLoS One (2011) 2.64
High affinity InhA inhibitors with activity against drug-resistant strains of Mycobacterium tuberculosis. ACS Chem Biol (2006) 2.50
Prokaryotic nucleotide excision repair: the UvrABC system. Chem Rev (2006) 2.37
The crystal structure of plant sulfite oxidase provides insights into sulfite oxidation in plants and animals. Structure (2003) 2.15
Basal transcription defect discriminates between xeroderma pigmentosum and trichothiodystrophy in XPD patients. Mol Cell (2003) 2.12
Integrating phenotypic and expression profiles to map arsenic-response networks. Genome Biol (2004) 1.90
Constitutive activation of PKA catalytic subunit in adrenal Cushing's syndrome. N Engl J Med (2014) 1.89
High-mobility group box 1 is essential for mitochondrial quality control. Cell Metab (2011) 1.89
Functional human mitochondrial DNA polymerase gamma forms a heterotrimer. J Biol Chem (2005) 1.85
Adipose tissue and adipocytes support tumorigenesis and metastasis. Biochim Biophys Acta (2013) 1.85
Lesion (in)tolerance reveals insights into DNA replication fidelity. EMBO J (2004) 1.83
Crystal structure of the FeS cluster-containing nucleotide excision repair helicase XPD. PLoS Biol (2008) 1.81
Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair. Nature (2011) 1.80
Role of mitochondria in toxic oxidative stress. Mol Interv (2005) 1.76
Alterations in bioenergetics due to changes in mitochondrial DNA copy number. Methods (2010) 1.62
NIEHS extramural global environmental health portfolio: opportunities for collaboration. Environ Health Perspect (2008) 1.61
Mitochondrial dysfunction in neurodegenerative diseases and cancer. Environ Mol Mutagen (2010) 1.60
Mitochondrial DNA repair and aging. Mutat Res (2002) 1.60
Slow-onset inhibition of the FabI enoyl reductase from francisella tularensis: residence time and in vivo activity. ACS Chem Biol (2009) 1.53
Structural basis for DNA recognition and processing by UvrB. Nat Struct Mol Biol (2006) 1.51
Crystal structures of Mycobacterium tuberculosis KasA show mode of action within cell wall biosynthesis and its inhibition by thiolactomycin. Structure (2009) 1.50
Cell sorting experiments link persistent mitochondrial DNA damage with loss of mitochondrial membrane potential and apoptotic cell death. J Biol Chem (2002) 1.49
Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species. PLoS One (2011) 1.48
DNA binding cooperativity of p53 modulates the decision between cell-cycle arrest and apoptosis. Mol Cell (2010) 1.47
Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cells. J Biol Chem (2010) 1.46
Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans. Genome Biol (2007) 1.41
A slow, tight binding inhibitor of InhA, the enoyl-acyl carrier protein reductase from Mycobacterium tuberculosis. J Biol Chem (2010) 1.41
Collaborative dynamic DNA scanning by nucleotide excision repair proteins investigated by single- molecule imaging of quantum-dot-labeled proteins. Mol Cell (2010) 1.40
Metabolic symbiosis in cancer: refocusing the Warburg lens. Mol Carcinog (2012) 1.40
Measuring oxidative mtDNA damage and repair using quantitative PCR. Methods Mol Biol (2002) 1.40
'Close-fitting sleeves': DNA damage recognition by the UvrABC nuclease system. Mutat Res (2005) 1.39
Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis. J Biol Chem (2003) 1.37
Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage. Aging Cell (2004) 1.37
Crystal structures of the active and alloxanthine-inhibited forms of xanthine dehydrogenase from Rhodobacter capsulatus. Structure (2002) 1.35
Mitochondrial localization of telomerase as a determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptosis. Hum Mol Genet (2006) 1.32
Altered gene expression and DNA damage in peripheral blood cells from Friedreich's ataxia patients: cellular model of pathology. PLoS Genet (2010) 1.32
Structural insights into the first incision reaction during nucleotide excision repair. EMBO J (2005) 1.30
Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress. J Cell Sci (2012) 1.30
Homologous recombination but not nucleotide excision repair plays a pivotal role in tolerance of DNA-protein cross-links in mammalian cells. J Biol Chem (2009) 1.29
Conceptual model of comprehensive research metrics for improved human health and environment. Environ Health Perspect (2008) 1.29
Functional and structural studies of the nucleotide excision repair helicase XPD suggest a polarity for DNA translocation. EMBO J (2011) 1.28
Reduction in frataxin causes progressive accumulation of mitochondrial damage. Hum Mol Genet (2003) 1.24
Double-strand break formation during nucleotide excision repair of a DNA interstrand cross-link. Biochemistry (2009) 1.23
Staphylococcus aureus FabI: inhibition, substrate recognition, and potential implications for in vivo essentiality. Structure (2012) 1.22
Structural insights into sulfite oxidase deficiency. J Biol Chem (2005) 1.21
Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress. Proc Natl Acad Sci U S A (2002) 1.20
UvrB domain 4, an autoinhibitory gate for regulation of DNA binding and ATPase activity. J Biol Chem (2006) 1.20
Initiation of repair of DNA-polypeptide cross-links by the UvrABC nuclease. Biochemistry (2005) 1.19
Asbestos induces mitochondrial DNA damage and dysfunction linked to the development of apoptosis. Am J Physiol Lung Cell Mol Physiol (2003) 1.18
Apoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG (5'-EXO/endonuclease) in their repair. J Biol Chem (2011) 1.18
Inhibiting systemic autophagy during interleukin 2 immunotherapy promotes long-term tumor regression. Cancer Res (2012) 1.17
Mitochondrial and nuclear DNA defects in Saccharomyces cerevisiae with mutations in DNA polymerase gamma associated with progressive external ophthalmoplegia. Hum Mol Genet (2005) 1.16
Prokaryotic nucleotide excision repair. Cold Spring Harb Perspect Biol (2013) 1.16
Probing for DNA damage with β-hairpins: similarities in incision efficiencies of bulky DNA adducts by prokaryotic and human nucleotide excision repair systems in vitro. DNA Repair (Amst) (2011) 1.15
Interactions between UvrA and UvrB: the role of UvrB's domain 2 in nucleotide excision repair. EMBO J (2004) 1.15
Structural basis of assembly chaperone- mediated snRNP formation. Mol Cell (2013) 1.13
Analysis of DNA damage and repair in nuclear and mitochondrial DNA of animal cells using quantitative PCR. Methods Mol Biol (2012) 1.13
Oxidants and not alkylating agents induce rapid mtDNA loss and mitochondrial dysfunction. DNA Repair (Amst) (2012) 1.12
Lysine 190 is the catalytic base in MenF, the menaquinone-specific isochorismate synthase from Escherichia coli: implications for an enzyme family. Biochemistry (2007) 1.10
Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination. Environ Mol Mutagen (2007) 1.10
Importance of glycolysis and oxidative phosphorylation in advanced melanoma. Mol Cancer (2012) 1.10
The C-terminal zinc finger of UvrA does not bind DNA directly but regulates damage-specific DNA binding. J Biol Chem (2006) 1.10
Mitochondrial structure, function and dynamics are temporally controlled by c-Myc. PLoS One (2012) 1.09
Structure of the C-terminal half of UvrC reveals an RNase H endonuclease domain with an Argonaute-like catalytic triad. EMBO J (2007) 1.09
Functional characterization and atomic force microscopy of a DNA repair protein conjugated to a quantum dot. Nano Lett (2008) 1.09
Toward the assessment of scientific and public health impacts of the National Institute of Environmental Health Sciences Extramural Asthma Research Program using available data. Environ Health Perspect (2009) 1.08
Sequence context- and temperature-dependent nucleotide excision repair of a benzo[a]pyrene diol epoxide-guanine DNA adduct catalyzed by thermophilic UvrABC proteins. Biochemistry (2007) 1.08
Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis. Biochemistry (2007) 1.08
Analyzing the handoff of DNA from UvrA to UvrB utilizing DNA-protein photoaffinity labeling. J Biol Chem (2004) 1.07
ATP13A2 regulates mitochondrial bioenergetics through macroautophagy. Neurobiol Dis (2011) 1.06
Repair activity of base and nucleotide excision repair enzymes for guanine lesions induced by nitrosative stress. Nucleic Acids Res (2005) 1.06
Rational optimization of drug-target residence time: insights from inhibitor binding to the Staphylococcus aureus FabI enzyme-product complex. Biochemistry (2013) 1.05
Characterizing septum inhibition in Mycobacterium tuberculosis for novel drug discovery. Tuberculosis (Edinb) (2008) 1.04
Mitochondria, energetics, epigenetics, and cellular responses to stress. Environ Health Perspect (2014) 1.03
DNA tandem lesion repair by strand displacement synthesis and nucleotide excision repair. Biochemistry (2008) 1.03
An altered redox balance mediates the hypersensitivity of Cockayne syndrome primary fibroblasts to oxidative stress. Aging Cell (2012) 1.02
Novel method for site-specific induction of oxidative DNA damage reveals differences in recruitment of repair proteins to heterochromatin and euchromatin. Nucleic Acids Res (2013) 1.02
Quantitative proteomics reveal ATM kinase-dependent exchange in DNA damage response complexes. J Proteome Res (2012) 1.01
Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways. J Biol Chem (2006) 1.01
3-nitropropionic acid-induced hydrogen peroxide, mitochondrial DNA damage, and cell death are attenuated by Bcl-2 overexpression in PC12 cells. Brain Res Mol Brain Res (2005) 1.01
An N-terminal clamp restrains the motor domains of the bacterial transcription-repair coupling factor Mfd. Nucleic Acids Res (2009) 0.99
Structural and functional characterization of the human DNA repair helicase XPD by comparative molecular modeling and site-directed mutagenesis of the bacterial repair protein UvrB. J Biol Chem (2002) 0.99