PubRank

M L Tremblay

Author PubWeight™ 70.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene. Science 1999 7.84
2 Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1. Nat Med 2001 4.19
3 The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene. J Exp Med 1995 3.86
4 TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B. J Biol Chem 2001 2.65
5 Identification of human adenovirus early region 1 products by using antisera against synthetic peptides corresponding to the predicted carboxy termini. J Virol 1983 2.35
6 Targeted ablation of the 25-hydroxyvitamin D 1alpha -hydroxylase enzyme: evidence for skeletal, reproductive, and immune dysfunction. Proc Natl Acad Sci U S A 2001 2.30
7 T cell development in mice that lack the zeta chain of the T cell antigen receptor complex. Science 1993 2.06
8 Animal model of Gaucher's disease from targeted disruption of the mouse glucocerebrosidase gene. Nature 1992 2.04
9 Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts. J Cell Biol 1999 2.00
10 Hindlimb patterning and mandible development require the Ptx1 gene. Development 1999 1.96
11 Impaired bone marrow microenvironment and immune function in T cell protein tyrosine phosphatase-deficient mice. J Exp Med 1997 1.82
12 Substrate-trapping techniques in the identification of cellular PTP targets. Methods 2005 1.60
13 Association of the multisubstrate docking protein Gab1 with the hepatocyte growth factor receptor requires a functional Grb2 binding site involving tyrosine 1356. J Biol Chem 1997 1.48
14 Ubiquinone is necessary for mouse embryonic development but is not essential for mitochondrial respiration. J Biol Chem 2001 1.42
15 In vitro cleavage specificity of the adenovirus type 2 proteinase. Biochim Biophys Acta 1983 1.40
16 Neuroendocrine dysplasia in mice lacking protein tyrosine phosphatase sigma. Nat Genet 1999 1.38
17 Cloning and characterization of a mouse cDNA encoding a cytoplasmic protein-tyrosine-phosphatase. Proc Natl Acad Sci U S A 1992 1.24
18 Attenuation of adhesion-dependent signaling and cell spreading in transformed fibroblasts lacking protein tyrosine phosphatase-1B. J Biol Chem 2001 1.23
19 Murine embryonic fibroblasts lacking TC-PTP display delayed G1 phase through defective NF-kappaB activation. Oncogene 2001 1.22
20 Receptor protein tyrosine phosphatase sigma inhibits axonal regeneration and the rate of axon extension. Mol Cell Neurosci 2003 1.22
21 Phosphotyrosine-independent binding of SHC to the NPLH sequence of murine protein-tyrosine phosphatase-PEST. Evidence for extended phosphotyrosine binding/phosphotyrosine interaction domain recognition specificity. J Biol Chem 1996 1.22
22 Mitochondrial NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is essential for embryonic development. Mol Cell Biol 2002 1.19
23 The T-cell protein tyrosine phosphatase. Semin Immunol 2000 1.17
24 Inactivation of the acid labile subunit gene in mice results in mild retardation of postnatal growth despite profound disruptions in the circulating insulin-like growth factor system. Proc Natl Acad Sci U S A 2000 1.16
25 Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylation. Mol Cell 2000 1.16
26 Murine protein tyrosine phosphatase-PEST, a stable cytosolic protein tyrosine phosphatase. Biochem J 1995 1.15
27 Targeting of the T-cell receptor zeta-chain gene in embryonic stem cells: strategies for generating multiple mutations in a single gene. Proc Natl Acad Sci U S A 1992 1.14
28 Intact LIM 3 and LIM 4 domains of paxillin are required for the association to a novel polyproline region (Pro 2) of protein-tyrosine phosphatase-PEST. J Biol Chem 1999 1.11
29 Hic-5, a paxillin homologue, binds to the protein-tyrosine phosphatase PEST (PTP-PEST) through its LIM 3 domain. J Biol Chem 1999 1.09
30 Roles of protein tyrosine phosphatases in cell migration and adhesion. Biochem Cell Biol 1999 1.08
31 Nuclear localization and cell cycle regulation of a murine protein tyrosine phosphatase. Mol Cell Biol 1994 1.07
32 Combination of gene targeting and substrate trapping to identify substrates of protein tyrosine phosphatases using PTP-PEST as a model. Biochemistry 1998 1.02
33 Activation and inhibition of expression of the 72,000-Da early protein of adenovirus type 5 in mouse cells constitutively expressing an immediate early protein of herpes simplex virus type 1. Virology 1985 0.98
34 Acylation of the 176R (19-kilodalton) early region 1B protein of human adenovirus type 5. J Virol 1987 0.96
35 Phosphorylation at serine 89 induces a shift in gel mobility but has little effect on the function of adenovirus type 5 E1A proteins. J Virol 1989 0.90
36 Coupling of the murine protein tyrosine phosphatase PEST to the epidermal growth factor (EGF) receptor through a Src homology 3 (SH3) domain-mediated association with Grb2. Oncogene 1997 0.89
37 Structure of the murine MPTP-PEST gene: genomic organization and chromosomal mapping. Genomics 1995 0.85
38 Molecular cloning and tissue-specific RNA processing of a murine receptor-type protein tyrosine phosphatase. Eur J Biochem 1994 0.82
39 Mapping of a phosphorylation site in the 176R (19 kDa) early region 1B protein of human adenovirus type 5. Virology 1989 0.81
40 Control of ALK (wild type and mutated forms) phosphorylation: specific role of the phosphatase PTP1B. Cell Signal 2013 0.80
41 Modulation of insulin signaling by protein tyrosine phosphatases. J Mol Med (Berl) 2000 0.80
42 Promoter analysis of the murine T-cell protein tyrosine phosphatase gene. Gene 1999 0.79
43 Physical mapping of receptor type protein tyrosine phosphatase sigma (PTPRS) to human chromosome 19p13.3. Genomics 1996 0.78
44 Thermosensitive mutants of the MPTP and hPTP1B protein tyrosine phosphatases: isolation and structural analysis. Protein Sci 1996 0.78
45 Role of the nuclear matrix in adenovirus maturation. Virus Res 1986 0.77
46 Regulation and role of the acid-labile subunit of the 150-kilodalton insulin-like growth factor complex in the mouse. Pediatr Nephrol 2000 0.76
47 Protein tyrosine phosphatases: new markers and targets in oncology? Curr Oncol 2008 0.76