Dendritic cells from patients with myeloma are numerically normal but functionally defective as they fail to up-regulate CD80 (B7-1) expression after huCD40LT stimulation because of inhibition by transforming growth factor-beta1 and interleukin-10.

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🔗 View Article (PMID 11698282)

Published in Blood on November 15, 2001

Authors

R D Brown1, B Pope, A Murray, W Esdale, D M Sze, J Gibson, P J Ho, D Hart, D Joshua

Author Affiliations

1: Institute of Haematology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia. rbrown@haem.rpa.cs.nsw.gov.au

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