A A Hyman

Author PubWeight™ 115.90‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III. Nature 2000 9.82
2 Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Nature 2005 9.50
3 Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau. Mol Biol Cell 1992 5.11
4 Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts. Cell 1990 4.92
5 Functional analysis of kinetochore assembly in Caenorhabditis elegans. J Cell Biol 2001 4.82
6 Rab5 regulates motility of early endosomes on microtubules. Nat Cell Biol 1999 4.74
7 The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast. Genes Dev 1999 4.69
8 Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts. Nat Cell Biol 2000 4.31
9 Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo. Nature 2001 4.15
10 Identification of essential components of the S. cerevisiae kinetochore. Cell 1993 4.03
11 Cytoplasmic dynein is required for distinct aspects of MTOC positioning, including centrosome separation, in the one cell stage Caenorhabditis elegans embryo. J Cell Biol 1999 3.97
12 Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans. J Cell Biol 2001 3.86
13 CYK-4: A Rho family gtpase activating protein (GAP) required for central spindle formation and cytokinesis. J Cell Biol 2000 3.55
14 Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation. Curr Biol 2001 3.13
15 Reconstitution of physiological microtubule dynamics using purified components. Science 2001 2.83
16 A requirement for Rho and Cdc42 during cytokinesis in Xenopus embryos. Curr Biol 1997 2.53
17 Structural changes at microtubule ends accompanying GTP hydrolysis: information from a slowly hydrolyzable analogue of GTP, guanylyl (alpha,beta)methylenediphosphonate. Proc Natl Acad Sci U S A 1998 2.43
18 Regulating the yeast kinetochore by ubiquitin-dependent degradation and Skp1p-mediated phosphorylation. Cell 1997 2.42
19 CDK1 inactivation regulates anaphase spindle dynamics and cytokinesis in vivo. J Cell Biol 1997 2.32
20 Factors required for the binding of reassembled yeast kinetochores to microtubules in vitro. J Cell Biol 1994 2.23
21 Molecular requirements for bi-directional movement of phagosomes along microtubules. J Cell Biol 1997 2.13
22 Pheromone induces programmed cell death in S. cerevisiae. Curr Biol 2002 2.13
23 Coupling cell division and cell death to microtubule dynamics. Curr Opin Cell Biol 1997 2.01
24 Distinct roles of PP1 and PP2A-like phosphatases in control of microtubule dynamics during mitosis. EMBO J 1997 1.85
25 Regulation of Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p. Genes Dev 1999 1.80
26 Straight GDP-tubulin protofilaments form in the presence of taxol. Curr Biol 2007 1.59
27 XMAP215 regulates microtubule dynamics through two distinct domains. EMBO J 2001 1.57
28 Structural transitions at microtubule ends correlate with their dynamic properties in Xenopus egg extracts. J Cell Biol 2000 1.51
29 Two genes required for the binding of an essential Saccharomyces cerevisiae kinetochore complex to DNA. Proc Natl Acad Sci U S A 1995 1.49
30 Mitotic chromatin regulates phosphorylation of Stathmin/Op18. Nature 1997 1.42
31 Preparation of marked microtubules for the assay of the polarity of microtubule-based motors by fluorescence microscopy. Methods Cell Biol 1993 1.42
32 A role for microtubule dynamics in phagosome movement. J Cell Sci 1998 1.37
33 zyg-8, a gene required for spindle positioning in C. elegans, encodes a doublecortin-related kinase that promotes microtubule assembly. Dev Cell 2001 1.27
34 Cortical domains and the mechanisms of asymmetric cell division. Trends Cell Biol 1996 1.17
35 Kinetochores distinguish GTP from GDP forms of the microtubule lattice. Nature 1997 1.16
36 Correct spindle elongation at the metaphase/anaphase transition is an APC-dependent event in budding yeast. J Cell Biol 2001 1.14
37 Microtubule-associated protein-dependent binding of phagosomes to microtubules. J Biol Chem 1996 1.14
38 Motor proteins of the eukaryotic cytoskeleton. Proc Natl Acad Sci U S A 1997 1.02
39 Microtubule structure and dynamics. Curr Opin Cell Biol 1997 1.01
40 OOC-3, a novel putative transmembrane protein required for establishment of cortical domains and spindle orientation in the P(1) blastomere of C. elegans embryos. Development 2000 0.90
41 Cell polarity. The importance of being polar. Curr Biol 1995 0.85
42 Spindle positioning during the asymmetric first cell division of Caenorhabditis elegans embryos. Novartis Found Symp 2001 0.80
43 In vitro reconstitution of endosome motility along microtubules. Methods Mol Biol 2001 0.78
44 Cell fate determination. When is a determinant a determinant? Curr Biol 1994 0.76