Published in Am J Respir Crit Care Med on November 01, 2001
Updated evidence-based treatment algorithm in pulmonary arterial hypertension. J Am Coll Cardiol (2009) 2.57
Home oxygen for children: who, how and when? Thorax (2005) 1.43
Treatment of pediatric pulmonary hypertension. Vasc Health Risk Manag (2009) 0.80
Insight into Pulmonary Arterial Hypertension Associated with Congenital Heart Disease (PAH-CHD): Classification and Pharmacological Management from a Pediatric Cardiological Point of View. Zhonghua Minguo Xin Zang Xue Hui Za Zhi (2015) 0.79
Endothelin receptor antagonists improve exercise tolerance and oxygen saturations in patients with Eisenmenger syndrome and congenital heart defects. Tex Heart Inst J (2008) 0.78
Initiating treatment with modafinil for control of excessive daytime sleepiness in patients switching from methylphenidate: an open-label safety study assessing three strategies. Psychopharmacology (Berl) (2003) 0.76
Pulmonary arterial hypertension associated with congenital heart disease and Eisenmenger syndrome: current practice in pediatrics. Minerva Pediatr (2015) 0.76
Recent strategies in treatment of pulmonary arterial hypertension, a review. Glob J Health Sci (2015) 0.76
The Changing Landscape of Pulmonary Arterial Hypertension in the Adult with Congenital Heart Disease. J Clin Med (2017) 0.75
Saudi Guidelines on the Diagnosis and Treatment of Pulmonary Hypertension: General management for pulmonary hypertension. Ann Thorac Med (2014) 0.75
Nocturnal hypoxaemia in patients with Eisenmenger syndrome: a cohort study. BMJ Open (2013) 0.75
The Adult Patient with Eisenmenger Syndrome: A Medical Update after Dana Point Part II: Medical Treatment - Study Results. Curr Cardiol Rev (2010) 0.75
A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene. Nature (1982) 11.92
T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALB- and Harvey-MSV transforming genes. Nature (1982) 4.54
Oncogenes in solid human tumours. Nature (1982) 3.00
Malignant activation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient. Science (1984) 2.97
Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development. Mol Cell Biol (2001) 2.60
Oncogenes in human tumor cell lines: molecular cloning of a transforming gene from human bladder carcinoma cells. Proc Natl Acad Sci U S A (1982) 2.55
Buprenorphine maintenance treatment of opiate dependence: a multicenter, randomized clinical trial. Addiction (1998) 2.47
Surgical treatment for secundum atrial septal defects in patients >40 years old. A randomized clinical trial. J Am Coll Cardiol (2001) 2.21
ras gene Amplification and malignant transformation. Mol Cell Biol (1985) 2.02
Expression of normal and transforming H-ras genes in Escherichia coli and purification of their encoded p21 proteins. Proc Natl Acad Sci U S A (1984) 1.94
Spontaneous activation of a human proto-oncogene. Proc Natl Acad Sci U S A (1983) 1.90
Isolation and molecular characterization of the Arabidopsis TPS1 gene, encoding trehalose-6-phosphate synthase. Plant J (1998) 1.60
Characterization of fat-storing cell lines derived from normal and CCl4-cirrhotic livers. Differences in the production of interleukin-6. Lab Invest (1991) 1.56
Characterization of syntenin, a syndecan-binding PDZ protein, as a component of cell adhesion sites and microfilaments. Mol Biol Cell (2001) 1.56
Localization of the normal allele of T24 human bladder carcinoma oncogene to chromosome 11. Nature (1982) 1.48
Measurement of the depth of maximum of extensive air showers above 10{18} eV. Phys Rev Lett (2010) 1.48
Pericardium-covered stent for septal myocardial ablation in hypertrophic obstructive cardiomyopathy. Catheter Cardiovasc Interv (1999) 1.44
Effect of body position changes on pulmonary gas exchange in Eisenmenger's syndrome. Am J Respir Crit Care Med (1999) 1.42
Suppression of the endogenous luteinizing hormone surge by the gonadotrophin-releasing hormone antagonist Cetrorelix during ovarian stimulation. Hum Reprod (1994) 1.41
Pulmonary arterial hypertension and cor pulmonale associated with chronic domestic woodsmoke inhalation. Chest (1993) 1.41
Right ventricular ischemia in patients with primary pulmonary hypertension. J Am Coll Cardiol (2001) 1.40
The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties. EMBO J (2000) 1.38
Mitogen-activated protein kinase activation is not necessary for, but antagonizes, 3T3-L1 adipocytic differentiation. Mol Cell Biol (1997) 1.35
Circadian studies of autonomic nervous balance in patients with fibromyalgia: a heart rate variability analysis. Arthritis Rheum (1998) 1.34
Graded balloon dilation atrial septostomy in severe primary pulmonary hypertension. A therapeutic alternative for patients nonresponsive to vasodilator treatment. J Am Coll Cardiol (1998) 1.29
Malignant transformation by ras and other oncogenes produces common alterations in inositol phospholipid signaling pathways. Proc Natl Acad Sci U S A (1988) 1.28
Myasthenia gravis and neuromyelitis optica spectrum disorder: a multicenter study of 16 patients. Neurology (2012) 1.25
Differentiation of 3T3-L1 fibroblasts to adipocytes induced by transfection of ras oncogenes. Science (1991) 1.22
Transforming genes in human tumors. J Cell Biochem (1982) 1.22
Induction of the HTLV-I LTR by Jun occurs through the Tax-responsive 21-bp elements. Virology (1991) 1.21
The ras signaling pathway mimics insulin action on glucose transporter translocation. Proc Natl Acad Sci U S A (1993) 1.20
The benefits of exercise for patients with haemophilia and recommendations for safe and effective physical activity. Haemophilia (2013) 1.18
Biochemical and biological comparison of HIV-1 NEF and ras gene products. Virology (1991) 1.16
Atrial septostomy for pulmonary hypertension. Clin Chest Med (2001) 1.11
Induction by NGF of meiotic maturation of Xenopus oocytes expressing the trk proto-oncogene product. Science (1991) 1.11
An epidermal growth factor receptor/ret chimera generates mitogenic and transforming signals: evidence for a ret-specific signaling pathway. Mol Cell Biol (1994) 1.07
Ras-guanine nucleotide exchange factor sos2 is dispensable for mouse growth and development. Mol Cell Biol (2000) 1.07
Activation of Ras by insulin in 3T3 L1 cells does not involve GTPase-activating protein phosphorylation. J Biol Chem (1992) 1.06
Oncogenic ras protein induces meiotic maturation of amphibian oocytes in the presence of protein synthesis inhibitors. FEBS Lett (1988) 1.05
Uptake of sucrose by Saccharomyces cerevisiae. Arch Biochem Biophys (1982) 1.05
Expression of alternative forms of Ras exchange factors GRF and SOS1 in different human tissues and cell lines. Oncogene (1996) 1.04
Antidepressant effect of transdermal nicotine patches in nonsmoking patients with major depression. J Clin Psychiatry (1996) 1.03
The adult patient with native coarctation of the aorta: balloon angioplasty or primary stenting? Heart (2003) 1.03
The ras oncoprotein and M-phase activity. Science (1991) 1.03
Endemic fluorosis in San Luis Potosi, Mexico. I. Identification of risk factors associated with human exposure to fluoride. Environ Res (1995) 1.03
A novel insertional mutation in the TC21 gene activates its transforming activity in a human leiomyosarcoma cell line. Oncogene (1995) 1.02
Effects of coumarin and 7OH-coumarin on bcl-2 and Bax expression in two human lung cancer cell lines in vitro. Cell Biol Int (2005) 0.99
Transcriptional networks of knockout cell lines identify functional specificities of H-Ras and N-Ras: significant involvement of N-Ras in biotic and defense responses. Oncogene (2006) 0.98
Influence of pregnancy on neuromyelitis optica spectrum disorder. Neurology (2012) 0.97
Dissociation between activation of Raf-1 kinase and the 42-kDa mitogen-activated protein kinase/90-kDa S6 kinase (MAPK/RSK) cascade in the insulin/Ras pathway of adipocytic differentiation of 3T3 L1 cells. J Biol Chem (1994) 0.97
Nonspecific suppressor cells in patients with chronic graft-vs-host disease after marrow grafting. J Immunol (1979) 0.97
Effect of atrial septostomy on the survival of patients with severe pulmonary arterial hypertension. Eur Respir J (2011) 0.96
p21ras-induced meiotic maturation of Xenopus oocytes in the absence of protein synthesis: MPF activation is preceded by activation of MAP and S6 kinases. Oncogene (1993) 0.95
Effect of porcine reproductive and respiratory syndrome virus infection on the clearance of Haemophilus parasuis by porcine alveolar macrophages. Can J Vet Res (1998) 0.94
The adult patient with Ebstein anomaly. Outcome in 72 unoperated patients. Medicine (Baltimore) (2000) 0.94
Small bowel obstruction and perforation after colonoscopy. Endoscopy (2003) 0.93
Peripheral airways obstruction in idiopathic pulmonary artery hypertension (primary). Chest (1983) 0.91
Laser microdissection and microarray analysis of the hippocampus of Ras-GRF1 knockout mice reveals gene expression changes affecting signal transduction pathways related to memory and learning. Neuroscience (2007) 0.91
In vitro synthesis of the membrane-bound D-lactate dehydrogenase of Escherichia coli. Biochemistry (1982) 0.90
Exudation of low molecular weight compounds (thiobismethane, methyl isocyanide, and methyl isothiocyanate) as a possible chemical defense mechanism in the marine sponge Ircinia felix. Biochem Syst Ecol (2001) 0.90
Increased intracellular glycerophosphoinositol is a biochemical marker for transformation by membrane-associated and cytoplasmic oncogenes. Biochem Biophys Res Commun (1990) 0.90
A 15 amino acid stretch close to the Grb2-binding domain defines two differentially expressed hSos1 isoforms with markedly different Grb2 binding affinity and biological activity. Oncogene (1996) 0.89
[Successful endoscopic therapy in a case of Bouveret's syndrome]. Rev Esp Enferm Dig (1994) 0.88
Establishment of permanent brown adipocyte cell lines achieved by transfection with SV40 large T antigen and ras genes. Exp Cell Res (1993) 0.87
Plasmodium falciparum EBA-175 kDa protein peptides which bind to human red blood cells. Parasitology (2000) 0.87
Primary antiphospholipid syndrome presenting as chronic thromboembolic pulmonary hypertension. Treatment with thromboendarterectomy. J Rheumatol (1996) 0.87
Impaired hepatic extraction and increased splanchnic production contribute to lactic acidosis in canine sepsis. Am J Respir Crit Care Med (2000) 0.87
Treatment of type II endoleaks after endovascular repair of abdominal aortic aneurysms: translumbar puncture and injection of thrombin into the aneurysm sac. Eur J Vasc Endovasc Surg (2004) 0.86
Developmental characterization and chromosomal mapping of the 5-azacytidine-sensitive fluF locus of Aspergillus nidulans. Mol Cell Biol (1988) 0.85
Isoform-specific insertion near the Grb2-binding domain modulates the intrinsic guanine nucleotide exchange activity of hSos1. Oncogene (1999) 0.84
The isoform-specific stretch of hSos1 defines a new Grb2-binding domain. Oncogene (2000) 0.84
Involvement of the proton electrochemical gradient in genetic transformation in Escherichia coli. Biochem Biophys Res Commun (1981) 0.84
Lymphadenitis caused by Aerococcus urinae infection. Scand J Infect Dis (2003) 0.84
Vitreous levels of interleukine-8 and monocyte chemoattractant protein-1 in macular oedema with branch retinal vein occlusion. Eye (Lond) (2010) 0.83
Transformation suppressor activity of C3G is independent of its CDC25-homology domain. Oncogene (1998) 0.83
Isolation of human monoclonal antibodies binding to B fragment of diphtheria toxin. Hum Antibodies Hybridomas (1992) 0.83
Biological activity of p27kip1 and its amino- and carboxy-terminal domains in G2/M transition of Xenopus oocytes. Oncogene (1997) 0.82
Why is gold such a good catalyst for oxygen reduction in alkaline media? Angew Chem Int Ed Engl (2012) 0.82
Protective role of the HLA-A*02 allele in Portuguese patients with multiple sclerosis. Mult Scler (2009) 0.82
[Suppression of endogenous LH increase in ovarian stimulation with the GnRH antagonist Cetrorelix]. Geburtshilfe Frauenheilkd (1994) 0.82
Endectocide activity of a new long-action formulation containing 2.25% ivermectin+1.25% abamectin in cattle. Vet Parasitol (2008) 0.81
Characterization of a human transforming gene isolated from T24 bladder carcinoma cells. Fed Proc (1984) 0.81
A divalent metal ion binding site in the kinase insert domain of the alpha-platelet-derived growth factor receptor regulates its association with SH2 domains. Biochemistry (1995) 0.81
Carboxyl-terminal domain of p27Kip1 activates CDC2. J Biol Chem (1997) 0.81
Behçet's disease and Chiari's network. Clin Rheumatol (2007) 0.81
[Sotos syndrome associated with focal dystonia]. Rev Neurol (1999) 0.81
Unexpected isolation of Bordetella pertussis from a blood culture. J Clin Microbiol (1994) 0.81
Human dual specificity phosphatase VHR activates maturation promotion factor and triggers meiotic maturation in Xenopus oocytes. J Biol Chem (1995) 0.81
The insulin/Ras pathway of adipocytic differentiation of 3T3 L1 cells: dissociation between Raf-1 kinase and the MAPK/RSK cascade. Int J Obes Relat Metab Disord (1996) 0.81
Effect of sitaxsentan treatment on quality of life in pulmonary arterial hypertension. Int J Clin Pract (2007) 0.80
Alterations of G-protein coupling function in phosphoinositide signaling pathways of cells transformed by ras and other membrane-associated and cytoplasmic oncogenes. Mol Cell Biol (1990) 0.80
Vav and Ras induce fibroblast transformation by overlapping signaling pathways which require c-Myc function. Oncogene (1995) 0.80
Molecular analysis of FVIII gene in severe HA patients of Costa Rica. Hamostaseologie (2010) 0.80
Acute graft-versus-host disease (aGVHD) presenting with an acquired lupus anticoagulant. Bone Marrow Transplant (2003) 0.80
Assessment of insecticide resistance in five insect pests attacking field and vegetable crops in Nicaragua. J Econ Entomol (2000) 0.80