| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Myocardial fatty acid metabolism in health and disease.
|
Physiol Rev
|
2010
|
4.49
|
|
2
|
Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes.
|
Mol Cell Biol
|
2011
|
2.23
|
|
3
|
Impaired myocardial metabolic reserve and substrate selection flexibility during stress in patients with idiopathic dilated cardiomyopathy.
|
Am J Physiol Heart Circ Physiol
|
2007
|
1.86
|
|
4
|
Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria.
|
J Lipid Res
|
2011
|
1.79
|
|
5
|
Carnitine palmitoyl transferase-I inhibition prevents ventricular remodeling and delays decompensation in pacing-induced heart failure.
|
Cardiovasc Res
|
2005
|
1.70
|
|
6
|
Role of diet and fuel overabundance in the development and progression of heart failure.
|
Cardiovasc Res
|
2008
|
1.70
|
|
7
|
Impaired myocardial fatty acid oxidation and reduced protein expression of retinoid X receptor-alpha in pacing-induced heart failure.
|
Circulation
|
2002
|
1.65
|
|
8
|
Bioinformatic profiling of the transcriptional response of adult rat cardiomyocytes to distinct fatty acids.
|
J Lipid Res
|
2008
|
1.63
|
|
9
|
Fish oil, but not flaxseed oil, decreases inflammation and prevents pressure overload-induced cardiac dysfunction.
|
Cardiovasc Res
|
2008
|
1.62
|
|
10
|
Low carbohydrate/high-fat diet attenuates cardiac hypertrophy, remodeling, and altered gene expression in hypertension.
|
Hypertension
|
2006
|
1.56
|
|
11
|
Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death.
|
Am J Physiol Heart Circ Physiol
|
2011
|
1.53
|
|
12
|
Differential effects of saturated and unsaturated fatty acid diets on cardiomyocyte apoptosis, adipose distribution, and serum leptin.
|
Am J Physiol Heart Circ Physiol
|
2006
|
1.52
|
|
13
|
Validation of echocardiographic methods for assessing left ventricular dysfunction in rats with myocardial infarction.
|
Am J Physiol Heart Circ Physiol
|
2004
|
1.52
|
|
14
|
CVT-4325 inhibits myocardial fatty acid uptake and improves left ventricular systolic function without increasing myocardial oxygen consumption in dogs with chronic heart failure.
|
Cardiovasc Drugs Ther
|
2007
|
1.52
|
|
15
|
Cardiac energy metabolism in obesity.
|
Circ Res
|
2007
|
1.51
|
|
16
|
Dietary supplementation with omega-3 PUFA increases adiponectin and attenuates ventricular remodeling and dysfunction with pressure overload.
|
Cardiovasc Res
|
2007
|
1.50
|
|
17
|
Paradoxical downregulation of the glucose oxidation pathway despite enhanced flux in severe heart failure.
|
J Mol Cell Cardiol
|
2004
|
1.49
|
|
18
|
Modulating fatty acid oxidation in heart failure.
|
Cardiovasc Res
|
2011
|
1.37
|
|
19
|
omega-3 polyunsaturated fatty acid supplementation for the treatment of heart failure: mechanisms and clinical potential.
|
Cardiovasc Res
|
2009
|
1.32
|
|
20
|
Dietary omega-3 fatty acids alter cardiac mitochondrial phospholipid composition and delay Ca2+-induced permeability transition.
|
J Mol Cell Cardiol
|
2009
|
1.28
|
|
21
|
High-fat diet prevents cardiac hypertrophy and improves contractile function in the hypertensive dahl salt-sensitive rat.
|
Clin Exp Pharmacol Physiol
|
2005
|
1.24
|
|
22
|
Diabetes or peroxisome proliferator-activated receptor alpha agonist increases mitochondrial thioesterase I activity in heart.
|
J Lipid Res
|
2007
|
1.20
|
|
23
|
Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart.
|
Circ Res
|
2012
|
1.16
|
|
24
|
Ranolazine, a partial fatty acid oxidation (pFOX) inhibitor, improves left ventricular function in dogs with chronic heart failure.
|
J Card Fail
|
2002
|
1.16
|
|
25
|
Treatment with docosahexaenoic acid, but not eicosapentaenoic acid, delays Ca2+-induced mitochondria permeability transition in normal and hypertrophied myocardium.
|
J Pharmacol Exp Ther
|
2010
|
1.15
|
|
26
|
Mechanistic model of cardiac energy metabolism predicts localization of glycolysis to cytosolic subdomain during ischemia.
|
Am J Physiol Heart Circ Physiol
|
2005
|
1.14
|
|
27
|
Dietary supplementation with docosahexaenoic acid, but not eicosapentaenoic acid, dramatically alters cardiac mitochondrial phospholipid fatty acid composition and prevents permeability transition.
|
Biochim Biophys Acta
|
2010
|
1.14
|
|
28
|
High fructose diet increases mortality in hypertensive rats compared to a complex carbohydrate or high fat diet.
|
Am J Hypertens
|
2007
|
1.14
|
|
29
|
Effects of a high saturated fat diet on cardiac hypertrophy and dysfunction in response to pressure overload.
|
J Card Fail
|
2008
|
1.13
|
|
30
|
Short-term treatment with ranolazine improves mechanical efficiency in dogs with chronic heart failure.
|
Circ Res
|
2002
|
1.12
|
|
31
|
Cardiomyocyte-specific perilipin 5 overexpression leads to myocardial steatosis and modest cardiac dysfunction.
|
J Lipid Res
|
2013
|
1.12
|
|
32
|
The cardioprotective effects of fish oil during pressure overload are blocked by high fat intake: role of cardiac phospholipid remodeling.
|
Hypertension
|
2009
|
1.11
|
|
33
|
Regulation of pyruvate dehydrogenase activity and citric acid cycle intermediates during high cardiac power generation.
|
J Physiol
|
2004
|
1.10
|
|
34
|
Assessment of cardiac proteome dynamics with heavy water: slower protein synthesis rates in interfibrillar than subsarcolemmal mitochondria.
|
Am J Physiol Heart Circ Physiol
|
2013
|
1.10
|
|
35
|
A high-fat diet increases adiposity but maintains mitochondrial oxidative enzymes without affecting development of heart failure with pressure overload.
|
Am J Physiol Heart Circ Physiol
|
2009
|
1.10
|
|
36
|
Moderate severity heart failure does not involve a downregulation of myocardial fatty acid oxidation.
|
Am J Physiol Heart Circ Physiol
|
2004
|
1.09
|
|
37
|
Effects of chronic activation of peroxisome proliferator-activated receptor-alpha or high-fat feeding in a rat infarct model of heart failure.
|
Am J Physiol Heart Circ Physiol
|
2005
|
1.08
|
|
38
|
Preserved protein synthesis in the heart in response to acute fasting and chronic food restriction despite reductions in liver and skeletal muscle.
|
Am J Physiol Endocrinol Metab
|
2008
|
1.08
|
|
39
|
Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation.
|
Circ Res
|
2004
|
1.08
|
|
40
|
Too much or not enough of a good thing? Cardiac glucolipotoxicity versus lipoprotection.
|
J Mol Cell Cardiol
|
2010
|
1.07
|
|
41
|
Low-carbohydrate/high-fat diet attenuates pressure overload-induced ventricular remodeling and dysfunction.
|
J Card Fail
|
2008
|
1.06
|
|
42
|
Therapy with cardiac contractility modulation electrical signals improves left ventricular function and remodeling in dogs with chronic heart failure.
|
J Am Coll Cardiol
|
2007
|
1.05
|
|
43
|
High intake of saturated fat, but not polyunsaturated fat, improves survival in heart failure despite persistent mitochondrial defects.
|
Cardiovasc Res
|
2011
|
1.05
|
|
44
|
Plasma proteome dynamics: analysis of lipoproteins and acute phase response proteins with 2H2O metabolic labeling.
|
Mol Cell Proteomics
|
2012
|
1.05
|
|
45
|
The antioxidant tempol attenuates pressure overload-induced cardiac hypertrophy and contractile dysfunction in mice fed a high-fructose diet.
|
Am J Physiol Heart Circ Physiol
|
2008
|
1.04
|
|
46
|
Improved mitochondrial function with diet-induced increase in either docosahexaenoic acid or arachidonic acid in membrane phospholipids.
|
PLoS One
|
2012
|
1.03
|
|
47
|
Ranolazine combined with enalapril or metoprolol prevents progressive LV dysfunction and remodeling in dogs with moderate heart failure.
|
Am J Physiol Heart Circ Physiol
|
2008
|
1.03
|
|
48
|
Deleterious effects of sugar and protective effects of starch on cardiac remodeling, contractile dysfunction, and mortality in response to pressure overload.
|
Am J Physiol Heart Circ Physiol
|
2007
|
1.03
|
|
49
|
Effects of exercise training and diet on lipid kinetics during free fatty acid-induced insulin resistance in older obese humans with impaired glucose tolerance.
|
Am J Physiol Endocrinol Metab
|
2009
|
1.01
|
|
50
|
Reverse changes in cardiac substrate oxidation in dogs recovering from heart failure.
|
Am J Physiol Heart Circ Physiol
|
2008
|
1.01
|
|
51
|
Impact of glucose-6-phosphate dehydrogenase deficiency on the pathophysiology of cardiovascular disease.
|
Am J Physiol Heart Circ Physiol
|
2012
|
1.00
|
|
52
|
Potential impact of carbohydrate and fat intake on pathological left ventricular hypertrophy.
|
Cardiovasc Res
|
2006
|
1.00
|
|
53
|
Assessing the reversibility of the anaplerotic reactions of the propionyl-CoA pathway in heart and liver.
|
J Biol Chem
|
2003
|
0.99
|
|
54
|
High-sugar diets increase cardiac dysfunction and mortality in hypertension compared to low-carbohydrate or high-starch diets.
|
J Hypertens
|
2008
|
0.99
|
|
55
|
Reduced synthesis of NO causes marked alterations in myocardial substrate metabolism in conscious dogs.
|
Am J Physiol Endocrinol Metab
|
2002
|
0.99
|
|
56
|
Fatty acid oxidation in cardiac and skeletal muscle mitochondria is unaffected by deletion of CD36.
|
Arch Biochem Biophys
|
2007
|
0.99
|
|
57
|
Carnitine palmitoyl transferase-I inhibition is not associated with cardiac hypertrophy in rats fed a high-fat diet.
|
Clin Exp Pharmacol Physiol
|
2007
|
0.98
|
|
58
|
Regulation of lactate production at the onset of ischaemia is independent of mitochondrial NADH/NAD+: insights from in silico studies.
|
J Physiol
|
2005
|
0.97
|
|
59
|
Dissociation between gene and protein expression of metabolic enzymes in a rodent model of heart failure.
|
Eur J Heart Fail
|
2006
|
0.97
|
|
60
|
Mechanistic model of myocardial energy metabolism under normal and ischemic conditions.
|
Ann Biomed Eng
|
2002
|
0.97
|
|
61
|
Exogenous nitric oxide reduces glucose transporters translocation and lactate production in ischemic myocardium in vivo.
|
Proc Natl Acad Sci U S A
|
2005
|
0.96
|
|
62
|
Regulation of myocardial substrate metabolism during increased energy expenditure: insights from computational studies.
|
Am J Physiol Heart Circ Physiol
|
2006
|
0.95
|
|
63
|
Rapid attenuation of circadian clock gene oscillations in the rat heart following ischemia-reperfusion.
|
J Mol Cell Cardiol
|
2007
|
0.95
|
|
64
|
Differential effects of heptanoate and hexanoate on myocardial citric acid cycle intermediates following ischemia-reperfusion.
|
J Appl Physiol (1985)
|
2005
|
0.94
|
|
65
|
Effects of adiponectin deficiency on structural and metabolic remodeling in mice subjected to pressure overload.
|
Am J Physiol Heart Circ Physiol
|
2010
|
0.94
|
|
66
|
Altered expression of the adenine nucleotide translocase isoforms and decreased ATP synthase activity in skeletal muscle mitochondria in heart failure.
|
J Mol Cell Cardiol
|
2009
|
0.93
|
|
67
|
Role of the malate-aspartate shuttle on the metabolic response to myocardial ischemia.
|
J Theor Biol
|
2008
|
0.92
|
|
68
|
Enhanced resistance to permeability transition in interfibrillar cardiac mitochondria in dogs: effects of aging and long-term aldosterone infusion.
|
Am J Physiol Heart Circ Physiol
|
2012
|
0.92
|
|
69
|
ω-3 Polyunsaturated fatty acids prevent pressure overload-induced ventricular dilation and decrease in mitochondrial enzymes despite no change in adiponectin.
|
Lipids Health Dis
|
2010
|
0.91
|
|
70
|
Chronic activation of peroxisome proliferator-activated receptor-alpha with fenofibrate prevents alterations in cardiac metabolic phenotype without changing the onset of decompensation in pacing-induced heart failure.
|
J Pharmacol Exp Ther
|
2007
|
0.91
|
|
71
|
Fatty acid oxidation and its impact on response of spontaneously hypertensive rat hearts to an adrenergic stress: benefits of a medium-chain fatty acid.
|
Am J Physiol Heart Circ Physiol
|
2004
|
0.90
|
|
72
|
Quantitative assessment of anaplerosis from propionate in pig heart in vivo.
|
Am J Physiol Endocrinol Metab
|
2002
|
0.90
|
|
73
|
Does junk food lead to heart failure? Importance of dietary macronutrient composition in hypertension.
|
Hypertension
|
2009
|
0.90
|
|
74
|
Glucose 6-phosphate dehydrogenase deficiency increases redox stress and moderately accelerates the development of heart failure.
|
Circ Heart Fail
|
2012
|
0.88
|
|
75
|
Partial inhibition of fatty acid oxidation increases regional contractile power and efficiency during demand-induced ischemia.
|
Cardiovasc Res
|
2003
|
0.87
|
|
76
|
Metabolic approaches to the treatment of ischemic heart disease: the clinicians' perspective.
|
Heart Fail Rev
|
2002
|
0.87
|
|
77
|
Transient activation of p38 MAP kinase and up-regulation of Pim-1 kinase in cardiac hypertrophy despite no activation of AMPK.
|
J Mol Cell Cardiol
|
2008
|
0.86
|
|
78
|
Marine n3 polyunsaturated fatty acids enhance resistance to mitochondrial permeability transition in heart failure but do not improve survival.
|
Am J Physiol Heart Circ Physiol
|
2012
|
0.86
|
|
79
|
Common mechanisms for calorie restriction and adenylyl cyclase type 5 knockout models of longevity.
|
Aging Cell
|
2012
|
0.86
|
|
80
|
High-sugar intake does not exacerbate metabolic abnormalities or cardiac dysfunction in genetic cardiomyopathy.
|
Nutrition
|
2012
|
0.86
|
|
81
|
Metabolic therapies for heart disease: fish for prevention and treatment of cardiac failure?
|
Cardiovasc Res
|
2005
|
0.86
|
|
82
|
Metabolic response to an acute jump in cardiac workload: effects on malonyl-CoA, mechanical efficiency, and fatty acid oxidation.
|
Am J Physiol Heart Circ Physiol
|
2007
|
0.85
|
|
83
|
Regulation of cardiac malonyl-CoA content and fatty acid oxidation during increased cardiac power.
|
Am J Physiol Heart Circ Physiol
|
2005
|
0.85
|
|
84
|
Increased nonoxidative glycolysis despite continued fatty acid uptake during demand-induced myocardial ischemia.
|
Am J Physiol Heart Circ Physiol
|
2002
|
0.84
|
|
85
|
Effect of hyperglycemia and fatty acid oxidation inhibition during aerobic conditions and demand-induced ischemia.
|
Am J Physiol Heart Circ Physiol
|
2003
|
0.84
|
|
86
|
Chronic treatment with the peroxisome proliferator-activated receptor alpha agonist Wy-14,643 attenuates myocardial respiratory capacity and contractile function.
|
Mol Cell Biochem
|
2009
|
0.84
|
|
87
|
Extracellular matrix maturation in the left ventricle of normal and diabetic swine.
|
Diabetes Res Clin Pract
|
2003
|
0.83
|
|
88
|
Regulation of malonyl-CoA concentration and turnover in the normal heart.
|
J Biol Chem
|
2004
|
0.83
|
|
89
|
Expression of mitochondrial regulatory genes parallels respiratory capacity and contractile function in a rat model of hypoxia-induced right ventricular hypertrophy.
|
Mol Cell Biochem
|
2008
|
0.82
|
|
90
|
Acute vagal stimulation attenuates cardiac metabolic response to β-adrenergic stress.
|
J Physiol
|
2012
|
0.82
|
|
91
|
Regulation of cardiac energetics: role of redox state and cellular compartmentation during ischemia.
|
Ann N Y Acad Sci
|
2005
|
0.82
|
|
92
|
Impact of anaerobic glycolysis and oxidative substrate selection on contractile function and mechanical efficiency during moderate severity ischemia.
|
Am J Physiol Heart Circ Physiol
|
2008
|
0.82
|
|
93
|
Chronic hypoxia impairs cytochrome oxidase activity via oxidative stress in selected fetal Guinea pig organs.
|
Reprod Sci
|
2012
|
0.81
|
|
94
|
Malonyl-CoA decarboxylase inhibition as a novel approach to treat ischemic heart disease.
|
Cardiovasc Drugs Ther
|
2006
|
0.81
|
|
95
|
A radiochemical pyruvate dehydrogenase assay: activity in heart.
|
Anal Biochem
|
2003
|
0.81
|
|
96
|
Parallel activation of mitochondrial oxidative metabolism with increased cardiac energy expenditure is not dependent on fatty acid oxidation in pigs.
|
J Physiol
|
2006
|
0.80
|
|
97
|
Mouse strain-specific differences in cardiac metabolic enzyme activities observed in a model of isoproterenol-induced cardiac hypertrophy.
|
Clin Exp Pharmacol Physiol
|
2007
|
0.78
|
|
98
|
Dipropionylcysteine ethyl ester compensates for loss of citric acid cycle intermediates during post ischemia reperfusion in the pig heart.
|
Cardiovasc Drugs Ther
|
2009
|
0.78
|
|
99
|
Chronic treatment with trimetazidine reduces the upregulation of atrial natriuretic peptide in heart failure.
|
Fundam Clin Pharmacol
|
2006
|
0.78
|
|
100
|
Altered cardiac metabolic phenotype after prolonged inhibition of NO synthesis in chronically instrumented dogs.
|
Am J Physiol Heart Circ Physiol
|
2006
|
0.78
|
|
101
|
Assay of the activity of malonyl-coenzyme A decarboxylase by gas chromatography-mass spectrometry.
|
Anal Biochem
|
2007
|
0.77
|
|
102
|
Dietary saturated fat and docosahexaenoic acid differentially effect cardiac mitochondrial phospholipid fatty acyl composition and Ca(2+) uptake, without altering permeability transition or left ventricular function.
|
Physiol Rep
|
2013
|
0.77
|
|
103
|
Effects of glucose-6-phosphate dehydrogenase deficiency on the metabolic and cardiac responses to obesogenic or high-fructose diets.
|
Am J Physiol Endocrinol Metab
|
2012
|
0.77
|
|
104
|
Metabolic therapy for heart disease: impact of trimetazidine.
|
Heart Fail Rev
|
2005
|
0.76
|
|
105
|
Docosahexaenoic acid supplementation alters key properties of cardiac mitochondria and modestly attenuates development of left ventricular dysfunction in pressure overload-induced heart failure.
|
Cardiovasc Drugs Ther
|
2013
|
0.76
|
|
106
|
Beneficial effects of acute inhibition of the oxidative pentose phosphate pathway in the failing heart.
|
Am J Physiol Heart Circ Physiol
|
2014
|
0.76
|
|
107
|
Combining protein ratio p-values as a pragmatic approach to the analysis of multirun iTRAQ experiments.
|
J Proteome Res
|
2015
|
0.76
|
|
108
|
Computational studies of the effects of myocardial blood flow reductions on cardiac metabolism.
|
Biomed Eng Online
|
2004
|
0.75
|
|
109
|
Partial fatty acid oxidation inhibitors: a potentially new class of drugs for heart failure.
|
Eur J Heart Fail
|
2002
|
0.75
|
|
110
|
The role of Ca2+ in coupling cardiac metabolism with regulation of contraction: in silico modeling.
|
Ann N Y Acad Sci
|
2008
|
0.75
|
|
111
|
Metabolomic analysis of two different models of delayed preconditioning.
|
J Mol Cell Cardiol
|
2012
|
0.75
|
|
112
|
Effect of a high-protein diet on development of heart failure in response to pressure overload.
|
Appl Physiol Nutr Metab
|
2013
|
0.75
|
|
113
|
Correction to "Combining Protein Ratio p-Values as a Pragmatic Approach to the Analysis of Multirun iTRAQ Experiments".
|
J Proteome Res
|
2015
|
0.75
|
|
114
|
Update on innovative initiatives for the American Journal of Physiology-Heart and Circulatory Physiology.
|
Am J Physiol Heart Circ Physiol
|
2013
|
0.75
|
|
115
|
[Potential impact of carbohydrate and fat intake on cardiac hypertrophy].
|
Kardiol Pol
|
2006
|
0.75
|
|
116
|
Diabetes and ischaemic heart disease: essential role for metabolic therapies.
|
Coron Artery Dis
|
2005
|
0.75
|
|
117
|
[Overview on omega-3 polyunsaturated fatty acids and heart failure].
|
Kardiol Pol
|
2010
|
0.75
|
|
118
|
Role of cellular compartmentation in the metabolic response to stress: mechanistic insights from computational models.
|
Ann N Y Acad Sci
|
2006
|
0.75
|
|
119
|
Nutrition and cardiovascular disease: putting a pathogenic framework into focus.
|
Cardiovasc Res
|
2006
|
0.75
|