Published in Oncology on January 01, 1979
Hypothalamic mechanisms of ageing and of specific age pathology--II. on the sensitivity threshold of hypothalamo-pituitary complex to homeostatic stimuli in adaptive homestasis. Exp Gerontol (1979) 1.39
Age-associated elevation of hypothalamic, threshold to feedback control, and its role in development, ageine, and disease. Lancet (1971) 1.37
Effect of treatment with phenformin, diphenylhydantoin or L-dopa on life span and tumour incidence in C3H/Sn mice. Gerontology (1980) 1.20
Have the oldest old adults ever been frail in the past? A hypothesis that explains modern trends in survival. J Gerontol A Biol Sci Med Sci (2001) 1.14
Mitochondrial-targeted plastoquinone derivatives. Effect on senescence and acute age-related pathologies. Curr Drug Targets (2011) 1.12
Inhibition of DMBA-induced carcinogenesis by phenformin in the mammary gland of rats. Arch Geschwulstforsch (1978) 1.05
[Effect of buformin and diphenylhydantoin on the life span, estrous function and spontaneous tumor incidence in rats]. Vopr Onkol (1980) 0.94
[Current approaches to the study of carcinogenic safety, antineoplastic, anticarcinogenic and geroprotective effects of various pharmacologic preparations]. Vopr Onkol (2012) 0.92
Hypothalmic mechanisms of ageing and of specific age pathology--I. Sensitivity threshold of hypothalamo-pituitary complex to homeostatic stimuli in the reproductive system. Exp Gerontol (1979) 0.91
Preliminary evidence on metabolic rehabilitation of cancer patients. Arch Geschwulstforsch (1988) 0.91
Potentiation of antitumor effect of cyclophosphamide and hydrazine sulfate by treatment with the antidiabetic agent, 1-phenylethylbiguanide (phenformin). Cancer Lett (1979) 0.88
Promotion of skin tumors by 12-O-tetradecanoylphorbol-13-acetate in two generations of descendants of male mice exposed to X-ray irradiation. Mutat Res (1993) 0.88
Peculiarities of hyperlipidaemia in tumour patients. Br J Cancer (1981) 0.87
[Effect of fenformin on the blastomogenic action of 1,2-dimethylhydrazine in rats]. Vopr Onkol (1980) 0.87
Kinase mTOR: regulation and role in maintenance of cellular homeostasis, tumor development, and aging. Biochemistry (Mosc) (2014) 0.87
Melatonin and metformin inhibit skin carcinogenesis and lipid peroxidation induced by benz(a)pyrene in female mice. Bull Exp Biol Med (2011) 0.86
Neuroendocrine-ontogenetic mechanism of aging: toward an integrated theory of aging. Int Rev Neurobiol (1986) 0.85
The effect of light regimen and melatonin on the development of spontaneous mammary tumors in HER-2/neu transgenic mice is related to a downregulation of HER-2/neu gene expression. Neuro Endocrinol Lett (2001) 0.84
Ageing, metabolic immunodepression and carcinogenesis. Mech Ageing Dev (1978) 0.84
Mammary tumors in HER-2/NEU mice are characterized by low content of estrogen receptors-alpha and absence of progesterone receptors. Bull Exp Biol Med (2003) 0.84
Metabolic immunodepression and metabolic immunotherapy: an attempt of improvement in immunologic response in breast cancer patients by correction of metabolic disturbances. Oncology (1982) 0.84
Carcinogenesis and aging. III. The role of age in initiation and promotion of carcinogenesis. Exp Pathol (1982) 0.84
[The use of peptide bioregulators for cancer prevention: results of 35 years of research experience and perspectives]. Vopr Onkol (2009) 0.83
[Melatonin and metformin inhibit skin carcinogenesis induced by benz(a)pyrene in mice]. Vopr Onkol (2010) 0.83
Metabolic immunodepression which increases the risk of cancer. Lancet (1977) 0.83
Pathology of tumours in laboratory animals. Tumours of the rat. Tumours of the vagina, uterus and oviduct. IARC Sci Publ (1990) 0.83
Carcinogenesis and aging. Adv Cancer Res (1983) 0.82
[Metformin slows down ageing processes at the cellular level in SHR mice]. Tsitologiia (2011) 0.82
[Poly(ADP-ribosa)polymerase--the relationships with life span and carcinogenesis]. Adv Gerontol (2007) 0.81
Effects of melatonin on N-nitroso-N-methylurea-induced carcinogenesis in rats and mutagenesis in vitro (Ames test and COMET assay). Cancer Lett (1999) 0.80
K-ras codon 12 and 61 point mutations in bromodeoxyuridine- and N-nitrosomethylurea-induced rat renal mesenchymal tumors. Cancer Lett (1996) 0.80
[Inhibition of the blastomogenic effect of 7,12-dimethylbenz(a)anthracene in female rats by buformin, diphenin, a polypeptide pineal extract and L-DOPA]. Biull Eksp Biol Med (1980) 0.80
Age-associated accumulation of the apolipoprotein C-III gene T-455C polymorphism C allele in a Russian population. J Gerontol A Biol Sci Med Sci (2001) 0.80
Carcinogenesis and aging. I. Modifying effects of aging on N-methyl-N-nitrosourea-induced carcinogenesis in female rats. Exp Pathol (1981) 0.80
Effect of synthetic thymic and pineal peptides on biomarkers of ageing, survival and spontaneous tumour incidence in female CBA mice. Mech Ageing Dev (2001) 0.80
[Light-dark conditions, melatonin and risk of cancer]. Vopr Onkol (2006) 0.80
[Increase in longevity and a decrease in the frequency of tumors in C3H/Sn mice under the influence of fenformin and diphenin]. Dokl Akad Nauk SSSR (1979) 0.79
Hypothalamopituitary hyperactivity and endometrial carcinoma. Qualitative and quantitative disturbances in hormone production. Am J Obstet Gynecol (1968) 0.79
Dose-dependent inhibitory effect of melatonin on carcinogenesis induced by benzo[a]pyrene in mice. J Exp Clin Cancer Res (2006) 0.79
Effect of low-molecular-weight factors of thymus and pineal gland on life span and spontaneous tumour development in female mice of different age. Mech Ageing Dev (1989) 0.79
Effect of melatonin and pineal peptide preparation epithalamin on life span and free radical oxidation in Drosophila melanogaster. Mech Ageing Dev (1997) 0.79
[Phenformin elimination of the immunodepression caused by 1,2-dimethylhydrazine in rats]. Vopr Onkol (1977) 0.79
[Metformin effect on urethane-induced tumorigenesis in mice]. Vopr Onkol (2012) 0.79
[Melatonin inhibits urethane-induced carcinogenesis tumors in murine lung]. Vopr Onkol (2006) 0.78
[Age dynamics of angiogenesis markers in transgenic HER-2/neu (FBV/N) mammary adenocarcinoma-prone mice]. Vopr Onkol (2015) 0.78
Endocrine-metabolic criteria for distinguishing two pathogenetic types of breast cancer. Neoplasma (1977) 0.78
[Effect of an epiphyseal polypeptide preparation on life expectancy and frequency of spontaneous tumors in aged female rats]. Dokl Akad Nauk SSSR (1991) 0.78
Persistence of methylated purines in the DNA of various rat fetal and maternal tissues and carcinogenesis in the offspring following a single transplacental dose of N-methyl-N-nitrosourea. Int J Cancer (1983) 0.78
[Blood estradiol level and G2-chalone content in the vaginal mucosa in rats of different ages]. Probl Endokrinol (Mosk) (1981) 0.78
The inhibition of the transplacental blastomogenic effect of nitrosomethylurea by postnatal administration of buformin to rats. Carcinogenesis (1980) 0.78
Immunomodulatory synthetic dipeptide L-Glu-L-Trp slows down aging and inhibits spontaneous carcinogenesis in rats. Biogerontology (2000) 0.78
[An increase in hypothalamic sensitivity to the inhibiting effects of estrogens caused by use of L-DOPA, diphenine, epithalamin and phenformin in old rats]. Biull Eksp Biol Med (1975) 0.78
Effect of light/dark regimen on N-nitrosoethylurea-induced transplacental carcinogenesis in rats. Cancer Lett (2001) 0.78
Modulatory effects of melatonin on genotoxic response of reference mutagens in the Ames test and the comet assay. Mutat Res (1998) 0.78
Resistance to inhibiting effect of dexamethasone in patients with endogenous depression. Acta Psychiatr Scand (1980) 0.78
[The effect of the irradiation of male mice on the sensitivity of 2 generations of progeny to the action of the skin tumor promoter 12-0-tetradecanoylphorbol-13-acetate]. Vopr Onkol (1991) 0.78
Hypothalamic mechanisms of ageing and of specific age pathology--V. A model for the mechanism of human specific age pathology and natural death. Exp Gerontol (1979) 0.78
[Susceptibility of wild and knockout p53 FVB/N line mice to benz(a)pyrene-induced subcutaneous sarcoma]. Vopr Onkol (2002) 0.77
[Chromosomal damage in peripheral blood lymphocytes of rats in nitrosomethylurea-induced carcinogenesis]. Eksp Onkol (1990) 0.77
[Effects of radiation from video display terminals of personal computers on free radical processes in rats]. Biull Eksp Biol Med (1997) 0.77
Microvascular endothelium dysfunction in rats bearing 1,2-dimethylhydrazine-induced colon tumors. Cancer Lett (1999) 0.77
Role of age in host sensitivity to carcinogens. IARC Sci Publ (1983) 0.77
[Characteristics of dyslipidemia in cancer patients]. Vopr Onkol (1986) 0.77
[Dynamics of the transplacental penetration of 7,12-dimethylbenz(a)anthracene (DMBA) in mice]. Vopr Onkol (1973) 0.77
[Free-radical processes in blood serum, liver and large bowel during 1,2-dimethylhydrazine-induced carcinogenesis in rats]. Vopr Onkol (1997) 0.77
[Effect of radiation emitted from personal computer terminal on urethan-induced lung tumors in mice]. Vopr Onkol (1996) 0.77
Studies of cytokines in nerve tissue cultures. Neurosci Behav Physiol (2001) 0.77
[Effect of light regimens and melatonin on the homeostasis, life span and development of spontaneous tumors in female rats]. Adv Gerontol (2007) 0.77
Natural and synthetic thymic peptides as therapeutics for immune dysfunction. Int J Immunopharmacol (1998) 0.77
[Melatonin suppresses benz(a)pyrene-induced carcinogenesis in mice]. Vopr Onkol (2007) 0.76
[Relation of blood lipids and insulin to body fat content, body surface area and state of the subcutaneous fatty tissue in patients with breast and lung cancer]. Vopr Onkol (1985) 0.76
Morphology of experimentally induced tumors of the sympathetic nervous system in rats. Exp Toxicol Pathol (2004) 0.76
Long-live euthymic BALB/c-nu mice. I. Survival study suggests body weight as a life span predictor. Mech Ageing Dev (2001) 0.76
Hyperinsulinemia as a factor modifying sensitivity of endometrial carcinoma to hormonal influences. Eur J Gynaecol Oncol (1993) 0.76
Hypothalamic mechanisms of ageing and of specific age pathology--III. Sensitivity threshold of hypothalamo-pituitary complex to homeostatic stimuli in energy systems. Exp Gerontol (1979) 0.76
Increase with age in the hypothalamo-hypophyseal threshold to the inhibitory action of estrogens and the effect of pineal extract on this process. Bull Exp Biol Med (1974) 0.76
[Age-related characteristics of the effects of epithalamin on serotonin metabolism in the pineal gland of rats]. Biull Eksp Biol Med (1992) 0.76
Disturbances of diurnal rhythms of biogenic amines contents in hypothalamic nuclei as an evidence of neurotropic effects of enterotropic carcinogen 1,2-dimethylhydrazine. Neuro Endocrinol Lett (2001) 0.76
Expression of circadian Per1 and Per2 genes in the liver and breast tumor tissues of HER2/neu transgenic mice of different age. Bull Exp Biol Med (2011) 0.76
[The effect of an epiphyseal extract on regulation of fat-carbohydrate metabolism]. Probl Endokrinol (Mosk) (1976) 0.76
[Effect of thyroxine on the hypothalamic concentration of biogenic amines in rats of different ages]. Fiziol Zh SSSR Im I M Sechenova (1978) 0.76
[Features of carcinogenesis and aging in knockout male mice PARP-1]. Vopr Onkol (2010) 0.76
[Cancer risk in women: a possible connection with geographic and certain economic and social factors]. Vopr Onkol (2011) 0.76
[Effect of light regimens and melatonin on homeostasis, life span and spontaneous tumorigenesis in male rats]. Vopr Onkol (2008) 0.76
[Inhibition of the transplacental blastomogenic effect of N-nitrosomethylurea in rats by buformin]. Biull Eksp Biol Med (1980) 0.76
[Diethylnitrosamine-induced carcinogenesis in PARP-1(-/-) and PARP-1(+/+) mice]. Vopr Onkol (2009) 0.76
[Colon carcinogenesis in rat vs. variable light]. Vopr Onkol (2008) 0.76
Increase in lifespan of rats following polypeptide pineal extract treatment. Exp Pathol (Jena) (1979) 0.76