Published in Endocrinology on January 01, 2002
Helicobacter pylori persistence: biology and disease. J Clin Invest (2004) 4.75
Expression of ghrelin receptor mRNA in the rat and the mouse brain. J Comp Neurol (2006) 3.61
Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion. Diabetes (2008) 2.68
Absence of ghrelin protects against early-onset obesity. J Clin Invest (2005) 2.53
Antagonism of ghrelin receptor reduces food intake and body weight gain in mice. Gut (2003) 1.96
Diet and gastrointestinal bypass-induced weight loss: the roles of ghrelin and peptide YY. Diabetes (2011) 1.19
Anticipatory physiological regulation in feeding biology: cephalic phase responses. Appetite (2007) 1.13
Inhibition of adipogenesis by ghrelin. Mol Biol Cell (2004) 1.09
Structure and physiological actions of ghrelin. Scientifica (Cairo) (2013) 1.06
Ghrelin: integrative neuroendocrine peptide in health and disease. Ann Surg (2004) 1.06
Neuroendocrine factors in the regulation of inflammation: excessive adiposity and calorie restriction. Exp Gerontol (2008) 1.05
Central ghrelin regulates peripheral lipid metabolism in a growth hormone-independent fashion. Endocrinology (2009) 1.04
Postprandial inhibition of gastric ghrelin secretion by long-chain fatty acid through GPR120 in isolated gastric ghrelin cells and mice. Am J Physiol Gastrointest Liver Physiol (2012) 0.99
Interrelationships between ghrelin, insulin and glucose homeostasis: Physiological relevance. World J Diabetes (2014) 0.98
Breakfast with glycomacropeptide compared with amino acids suppresses plasma ghrelin levels in individuals with phenylketonuria. Mol Genet Metab (2010) 0.98
IA-2beta, but not IA-2, is induced by ghrelin and inhibits glucose-stimulated insulin secretion. Proc Natl Acad Sci U S A (2006) 0.97
Ghrelin: a new player in the control of gastrointestinal functions. Gut (2005) 0.97
Role of ghrelin and leptin in predicting the severity of acute pancreatitis. Dig Dis Sci (2007) 0.92
Upper gastrointestinal symptoms and associated disorders in morbidly obese patients: a prospective study. Dig Dis Sci (2008) 0.92
Diurnal rhythms of leptin and ghrelin in the systemic circulation and in the gastric mucosa are related to food intake in rats. Pflugers Arch (2004) 0.90
Direct effects of nutrients, acetylcholine, CCK, and insulin on ghrelin release from the isolated stomachs of rats. Peptides (2009) 0.89
The rabbit pup, a natural model of nursing-anticipatory activity. Eur J Neurosci (2009) 0.88
Integrating GHS into the Ghrelin System. Int J Pept (2010) 0.88
Ghrelin cells in the gastrointestinal tract. Int J Pept (2010) 0.87
Hormonal and metabolic rhythms associated with the daily scheduled nursing in rabbit pups. Am J Physiol Regul Integr Comp Physiol (2008) 0.87
Ghrelin in fetal thyroid and follicular tumors and cell lines: expression and effects on tumor growth. Am J Pathol (2003) 0.87
Nkx2.2 activates the ghrelin promoter in pancreatic islet cells. Mol Endocrinol (2009) 0.87
Ghrelin, appetite regulation, and food reward: interaction with chronic stress. Int J Pept (2011) 0.86
Characterization of the insulin sensitivity of ghrelin receptor KO mice using glycemic clamps. BMC Physiol (2011) 0.86
Prospective study of surgical treatment of acromegaly: effects on ghrelin, weight, adiposity, and markers of CV risk. J Clin Endocrinol Metab (2014) 0.84
Final answer: ghrelin can suppress insulin secretion in humans, but is it clinically relevant? Diabetes (2010) 0.84
Influence of a long-term high-fat diet on ghrelin secretion and ghrelin-induced food intake in rats. Regul Pept (2011) 0.84
Ghrelin modulates physiologic and pathologic retinal angiogenesis through GHSR-1a. Invest Ophthalmol Vis Sci (2011) 0.83
Ghrelin Levels in Gastric Mucosa before and after Eradication of Helicobacter pylori. Gut Liver (2007) 0.82
Altered ghrelin secretion in mice in response to diet-induced obesity and Roux-en-Y gastric bypass. Mol Metab (2014) 0.82
Fasting-induced increase in plasma ghrelin is blunted by intravenous alcohol administration: a within-subject placebo-controlled study. Psychoneuroendocrinology (2013) 0.81
Ablation of ghrelin O-acyltransferase does not improve glucose intolerance or body adiposity in mice on a leptin-deficient ob/ob background. PLoS One (2013) 0.80
Fish oil and olive oil can modify insulin resistance and plasma desacyl-ghrelin in rats. J Res Med Sci (2011) 0.80
Interactions of gastrointestinal peptides: ghrelin and its anorexigenic antagonists. Int J Pept (2010) 0.80
High fat feeding affects the number of GPR120 cells and enteroendocrine cells in the mouse stomach. Front Physiol (2015) 0.80
Effects of ghrelin on protein expression of antioxidative enzymes and iNOS in the rat liver. Arch Med Sci (2014) 0.79
Ghrelin promotes differentiation of human embryonic stem cells into cardiomyocytes. Acta Pharmacol Sin (2011) 0.79
Ghrelin secretion is not reduced by increased fat mass during diet-induced obesity. Am J Physiol Regul Integr Comp Physiol (2008) 0.79
Ghrelin-ghrelin O-acyltransferase system in the pathogenesis of nonalcoholic fatty liver disease. World J Gastroenterol (2015) 0.79
Methyl donor deficiency affects fetal programming of gastric ghrelin cell organization and function in the rat. Am J Pathol (2009) 0.78
Dietary Caprylic Acid (C8:0) Does Not Increase Plasma Acylated Ghrelin but Decreases Plasma Unacylated Ghrelin in the Rat. PLoS One (2015) 0.77
Neonatal events, such as androgenization and postnatal overfeeding, modify the response to ghrelin. Sci Rep (2014) 0.76
Characteristic features of ghrelin cells in the gastrointestinal tract and the regulation of stomach ghrelin expression and production. World J Gastroenterol (2008) 0.76
The Effect of Short-Term Dietary Fructose Supplementation on Gastric Emptying Rate and Gastrointestinal Hormone Responses in Healthy Men. Nutrients (2017) 0.75
The effect of ghrelin upon the early immune response in lean and obese mice during sepsis. PLoS One (2015) 0.75
Deletion of Gpr128 results in weight loss and increased intestinal contraction frequency. World J Gastroenterol (2014) 0.75
A study on the short-term effect of cafeteria diet and pioglitazone on insulin resistance and serum levels of adiponectin and ghrelin. Braz J Med Biol Res (2012) 0.75
The Role of the Autonomic Nervous System in the Pathophysiology of Obesity. Front Physiol (2017) 0.75
Ghrelin is present in pancreatic alpha-cells of humans and rats and stimulates insulin secretion. Diabetes (2002) 1.95
Weight loss increases circulating levels of ghrelin in human obesity. Clin Endocrinol (Oxf) (2002) 1.76
Molecular forms of hypothalamic ghrelin and its regulation by fasting and 2-deoxy-d-glucose administration. Endocrinology (2005) 1.63
Hyperglycaemia suppresses the secretion of ghrelin, a novel growth-hormone-releasing peptide: responses to the intravenous and oral administration of glucose. Clin Sci (Lond) (2002) 1.54
Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway. Nat Med (2004) 1.48
Overexpression of human adiponectin in transgenic mice results in suppression of fat accumulation and prevention of premature death by high-calorie diet. Am J Physiol Endocrinol Metab (2007) 1.48
Ghrelin directly regulates bone formation. J Bone Miner Res (2004) 1.44
Gene expression, secretion, and autocrine action of C-type natriuretic peptide in cultured adult rat cardiac fibroblasts. Endocrinology (2003) 1.40
Ingested medium-chain fatty acids are directly utilized for the acyl modification of ghrelin. Endocrinology (2005) 1.38
Plasma ghrelin and desacyl ghrelin concentrations in renal failure. J Am Soc Nephrol (2002) 1.37
International Union of Pharmacology. LVI. Ghrelin receptor nomenclature, distribution, and function. Pharmacol Rev (2005) 1.35
Central control of bone remodeling by neuromedin U. Nat Med (2007) 1.32
Biological, physiological, and pharmacological aspects of ghrelin. J Pharmacol Sci (2006) 1.30
Structural divergence of human ghrelin. Identification of multiple ghrelin-derived molecules produced by post-translational processing. J Biol Chem (2002) 1.30
Genomic structure and characterization of the 5'-flanking region of the human ghrelin gene. Endocrinology (2004) 1.30
Ghrelin modulates the downstream molecules of insulin signaling in hepatoma cells. J Biol Chem (2001) 1.28
Increased plasma ghrelin level in lung cancer cachexia. Clin Cancer Res (2003) 1.27
Ghrelin--not just another stomach hormone. Regul Pept (2002) 1.22
The role of ghrelin and growth hormone secretagogues receptor on rat adipogenesis. Endocrinology (2003) 1.19
Delayed short-term secretory regulation of ghrelin in obese animals: evidenced by a specific RIA for the active form of ghrelin. Endocrinology (2002) 1.19
Impaired mitochondrial respiration and protein nitration in the rat hippocampus after acute inhalation of combustion smoke. Toxicol Appl Pharmacol (2008) 1.18
Transgenic overexpression of neuroglobin attenuates formation of smoke-inhalation-induced oxidative DNA damage, in vivo, in the mouse brain. Free Radic Biol Med (2011) 1.15
Increased expression of hypoxia-inducible factor-1alpha, p48, and the Notch signaling cascade during acute pancreatitis in mice. Pancreas (2004) 1.06
Structure, regulation and function of ghrelin. J Biochem (2011) 1.05
The role of protein kinase D in neurotensin secretion mediated by protein kinase C-alpha/-delta and Rho/Rho kinase. J Biol Chem (2004) 1.04
Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. EMBO J (2005) 1.02
The gut-brain peptide neuromedin U is involved in the mammalian circadian oscillator system. Biochem Biophys Res Commun (2004) 0.98
Fasting plasma ghrelin levels are negatively correlated with insulin resistance and PAI-1, but not with leptin, in obese children and adolescents. Diabetes (2002) 0.98
Myristoylated alanine-rich C kinase substrate-mediated neurotensin release via protein kinase C-delta downstream of the Rho/ROK pathway. J Biol Chem (2004) 0.98
A rat model of smoke inhalation injury: influence of combustion smoke on gene expression in the brain. Toxicol Appl Pharmacol (2005) 0.96
Ghrelin and the regulation of food intake and energy balance. Mol Interv (2002) 0.95
Apelin, a new enteric peptide: localization in the gastrointestinal tract, ontogeny, and stimulation of gastric cell proliferation and of cholecystokinin secretion. Endocrinology (2003) 0.95
Structures and molecular forms of the ghrelin-family peptides. Peptides (2011) 0.94
Cardiovascular and hormonal effects of subcutaneous administration of ghrelin, a novel growth hormone-releasing peptide, in healthy humans. Clin Sci (Lond) (2003) 0.94
Rat MYH, a glycosylase for repair of oxidatively damaged DNA, has brain-specific isoforms that localize to neuronal mitochondria. J Neurochem (2002) 0.93
A transient surge of ghrelin secretion before feeding is modified by different feeding regimens in sheep. Biochem Biophys Res Commun (2002) 0.93
Elevated metals compromise repair of oxidative DNA damage via the base excision repair pathway: implications of pathologic iron overload in the brain on integrity of neuronal DNA. J Neurochem (2009) 0.93
Ghrelin immunoreactivity in human plasma is suppressed by somatostatin. Clin Endocrinol (Oxf) (2002) 0.92
Accumulation of oxidatively generated DNA damage in the brain: a mechanism of neurotoxicity. Free Radic Biol Med (2006) 0.92
Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines. Exp Hematol (2012) 0.92
Ghrelin O-acyltransferase (GOAT) has a preference for n-hexanoyl-CoA over n-octanoyl-CoA as an acyl donor. Biochem Biophys Res Commun (2009) 0.92
The role of ghrelin and ghrelin-receptor gene variants and promoter activity in type 2 diabetes. Eur J Endocrinol (2009) 0.91
DNA polymerase beta-catalyzed-PCNA independent long patch base excision repair synthesis: a mechanism for repair of oxidatively damaged DNA ends in post-mitotic brain. J Neurochem (2008) 0.91
Isolation of the bioactive peptides CCHamide-1 and CCHamide-2 from Drosophila and their putative role in appetite regulation as ligands for G protein-coupled receptors. Front Endocrinol (Lausanne) (2012) 0.91
Accumulation of oxidative DNA damage in brain mitochondria in mouse model of hereditary ferritinopathy. Neurosci Lett (2010) 0.91
Analysis of rat insulin II promoter-ghrelin transgenic mice and rat glucagon promoter-ghrelin transgenic mice. J Biol Chem (2005) 0.90
Maternal ghrelin plays an important role in rat fetal development during pregnancy. Endocrinology (2005) 0.90
The neuropeptide neuromedin U promotes inflammation by direct activation of mast cells. J Exp Med (2005) 0.90
Ghrelin directly stimulates adult hippocampal neurogenesis: implications for learning and memory. Endocr J (2013) 0.89
Neuromedin U is involved in nociceptive reflexes and adaptation to environmental stimuli in mice. Biochem Biophys Res Commun (2004) 0.89
Phorbol ester-mediated neurotensin secretion is dependent on the PKC-alpha and -delta isoforms. Am J Physiol Gastrointest Liver Physiol (2002) 0.89
Involvement of a Stat3 binding site in inflammation-induced enteric apelin expression. Am J Physiol Gastrointest Liver Physiol (2008) 0.88
Synergistic cytotoxicity of the DNA alkylating agent busulfan, nucleoside analogs and suberoylanilide hydroxamic acid in lymphoma cell lines. Leuk Lymphoma (2011) 0.88
A possible role for hypoxia-induced apelin expression in enteric cell proliferation. Am J Physiol Regul Integr Comp Physiol (2008) 0.88
Alteration of plasma ghrelin levels associated with the blood pressure in pregnancy. Hypertension (2002) 0.88
Production of n-octanoyl-modified ghrelin in cultured cells requires prohormone processing protease and ghrelin O-acyltransferase, as well as n-octanoic acid. J Biochem (2009) 0.88
Influencing the between-feeding and endocrine responses of plasma ghrelin in healthy dogs. Eur J Endocrinol (2005) 0.87
Regulation of ghrelin secretion during pregnancy and lactation in the rat: possible involvement of hypothalamus. Peptides (2004) 0.87
Nutrient inhibition of ghrelin secretion in the fasted rat. Regul Pept (2004) 0.87
Effect of chronic hyperghrelinemia on ingestive action of ghrelin. Am J Physiol Regul Integr Comp Physiol (2005) 0.87
Hypoxia induces mitochondrial DNA damage and stimulates expression of a DNA repair enzyme, the Escherichia coli MutY DNA glycosylase homolog (MYH), in vivo, in the rat brain. J Neurochem (2002) 0.86
Alterations in stomach ghrelin production and in ghrelin-induced growth hormone secretion in the aged rat. Mech Ageing Dev (2004) 0.86
Chicken ghrelin: purification, cDNA cloning, and biological activity. Endocrinology (2002) 0.86
Identification of the novel bioactive peptides dRYamide-1 and dRYamide-2, ligands for a neuropeptide Y-like receptor in Drosophila. Biochem Biophys Res Commun (2011) 0.86
Characterization and species differences in gastric ghrelin cells from mice, rats and hamsters. J Anat (2004) 0.86
Characterization and regulation of the rat and human ghrelin promoters. Endocrinology (2004) 0.86
Ghrelin and leptin: a link between obesity and allergy? J Allergy Clin Immunol (2006) 0.85
Peptide purification, complementary deoxyribonucleic acid (DNA) and genomic DNA cloning, and functional characterization of ghrelin in rainbow trout. Endocrinology (2003) 0.85
The potential of phage display virions expressing malignant tumor specific antigen MAGE-A1 epitope in murine model. Vaccine (2005) 0.85
Sustained hypoxia modulates mitochondrial DNA content in the neonatal rat brain. Free Radic Biol Med (2007) 0.85
The neuropeptide neuromedin U activates eosinophils and is involved in allergen-induced eosinophilia. Am J Physiol Lung Cell Mol Physiol (2005) 0.85
Influence of a long-term high-fat diet on ghrelin secretion and ghrelin-induced food intake in rats. Regul Pept (2011) 0.84
Nuclear depletion of apurinic/apyrimidinic endonuclease 1 (Ape1/Ref-1) is an indicator of energy disruption in neurons. Free Radic Biol Med (2012) 0.84
Regulation of gonadotropin secretion and puberty onset by neuromedin U. FEBS Lett (2006) 0.84
Identification of tilapia ghrelin and its effects on growth hormone and prolactin release in the tilapia, Oreochromis mossambicus. Comp Biochem Physiol B Biochem Mol Biol (2003) 0.84
Increased colonic apelin production in rodents with experimental colitis and in humans with IBD. Regul Pept (2007) 0.84
Involvement of cholinergic neurons in the regulation of the ghrelin secretory response to feeding in sheep. Biochem Biophys Res Commun (2003) 0.84
Ghrelin deficiency does not influence feeding performance. Regul Pept (2007) 0.84