Role of the renin-angiotensin system in vascular diseases: expanding the field.

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Published in Hypertension on December 01, 2001

Authors

M Ruiz-Ortega1, O Lorenzo, M Rupérez, V Esteban, Y Suzuki, S Mezzano, J J Plaza, J Egido

Author Affiliations

1: Laboratory of Vascular and Renal Pathology, Fundación Jiménez Díaz, Universidad Autónoma Madrid, Spain. mruizo@fjd.es

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Commonly deleted regions on the long arm of chromosome 21 in differentiated adenocarcinoma of the stomach. Genes Chromosomes Cancer (1997) 1.56