Published in Mol Cell Biol on June 01, 1982
High-efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol (1987) 43.61
Electroporation for the efficient transfection of mammalian cells with DNA. Nucleic Acids Res (1987) 12.80
Recombination in mouse L cells between DNA introduced into cells and homologous chromosomal sequences. Proc Natl Acad Sci U S A (1985) 2.79
Bacteriophage lambda vector for transducing a cDNA clone library into mammalian cells. Mol Cell Biol (1985) 2.35
Negative regulation of the major histocompatibility class I gene in undifferentiated embryonal carcinoma cells. Proc Natl Acad Sci U S A (1986) 1.90
A recB recC sbcB recJ host prevents recA-independent deletions in recombinant cosmid DNA propagated in Escherichia coli. J Bacteriol (1989) 1.90
Extrachromosomal recombination in mammalian cells as studied with single- and double-stranded DNA substrates. Mol Cell Biol (1987) 1.72
Polymorphic GGC repeat differentially regulates human reelin gene expression levels. J Neural Transm (Vienna) (2006) 0.95
Targeting choroid plexus epithelia and ventricular ependyma for drug delivery to the central nervous system. BMC Neurosci (2011) 0.81
Specific factors are required for kinase-dependent endocytosis of insulin receptors. Mol Biol Cell (1994) 0.77
p lambda Zd39: a new type of cDNA expression vector for low background, high efficiency directional cloning. Nucleic Acids Res (1991) 0.75
Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol (1975) 503.08
A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology (1973) 127.36
Nucleotide sequence of the rightward operator of phage lambda. Proc Natl Acad Sci U S A (1975) 56.75
Nature of Col E 1 plasmid replication in Escherichia coli in the presence of the chloramphenicol. J Bacteriol (1972) 46.61
General method for the isolation of plasmid deoxyribonucleic acid. J Bacteriol (1973) 31.68
The isolation and characterization of linked delta- and beta-globin genes from a cloned library of human DNA. Cell (1978) 22.88
Transformation of mammalian cells with genes from procaryotes and eucaryotes. Cell (1979) 21.15
Charon phages: safer derivatives of bacteriophage lambda for DNA cloning. Science (1977) 20.27
Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor. Cell (1978) 19.44
Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells. Cell (1977) 18.95
Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences. Nature (1981) 13.89
Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1. Proc Natl Acad Sci U S A (1981) 10.04
An improved technique for obtaining enhanced infectivity with herpes simplex virus type 1 DNA. J Gen Virol (1976) 8.07
Helper-independent transformation by unintegrated Harvey sarcoma virus DNA. J Virol (1978) 7.75
Cloning of the active thymidine kinase gene of herpes simplex virus type 1 in Escherichia coli K-12. Proc Natl Acad Sci U S A (1979) 7.24
Construction and analysis of simian virus 40 origins defective in tumor antigen binding and DNA replication. Proc Natl Acad Sci U S A (1980) 7.04
Genetic and physical linkage of exogenous sequences in transformed cells. Cell (1980) 6.67
Two types of ribosome in mouse-hamster hybrid cells. Nat New Biol (1971) 5.19
Hormone-responsive expression of an endogenous proviral gene of mouse mammary tumor virus after molecular cloning and gene transfer into cultured cells. Proc Natl Acad Sci U S A (1981) 4.30
Parameters governing the transfer of the genes for thymidine kinase and dihydrofolate reductase into mouse cells using metaphase chromosomes or DNA. Somatic Cell Genet (1980) 4.16
Transfer of the human gene for hypoxanthine-guanine phosphoribosyltransferase via isolated human metaphase chromosomes into mouse L-cells. Proc Natl Acad Sci U S A (1975) 3.91
Transfection by exogenous and endogenous murine retrovirus DNAs. Cell (1979) 2.75
Isolation of transforming DNA: cloning the hamster aprt gene. Cell (1980) 2.73
STUDIES ON THYMIDINE KINASE IN CULTURED MOUSE FIBROBLASTS. Biochim Biophys Acta (1965) 2.47
Hormonal inducibility of rat alpha 2u globulin genes in transfected mouse cells. Nature (1981) 2.05
Co-transfer of human X-linked markers into murine somatic cells via isolated metaphase chromosomes. Proc Natl Acad Sci U S A (1978) 1.73
Human gene expression in rodent cells after uptake of isolated metaphase chromosomes. Proc Natl Acad Sci U S A (1975) 1.47
Recovery of recombinant bacterial plasmids from E. coli transformed with DNA from microinjected mouse cells. Nucleic Acids Res (1981) 1.39
Biochemical transformation of thymidine kinase (TK)-deficient mouse cells by herpes simplex virus type 1 DNA fragments purified from hybrid plasmids. Nucleic Acids Res (1980) 1.00
Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction. Genomics (1989) 19.10
Frameshift mutations and the genetic code. This paper is dedicated to Professor Theodosius Dobzhansky on the occasion of his 66th birthday. Cold Spring Harb Symp Quant Biol (1966) 14.57
Transient left ventricular apical ballooning without coronary artery stenosis: a novel heart syndrome mimicking acute myocardial infarction. Angina Pectoris-Myocardial Infarction Investigations in Japan. J Am Coll Cardiol (2001) 12.56
A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature (1994) 9.31
Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell (1998) 8.16
[Myocardial stunning due to simultaneous multivessel coronary spasms: a review of 5 cases]. J Cardiol (1991) 7.95
Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice. Mol Cell (1998) 7.46
The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307). J Biol Chem (2000) 7.41
DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs. Genes Dev (1998) 6.96
Conservation of primary structure in 16S ribosomal RNA. Nature (1975) 5.88
A precise and fast temperature mapping using water proton chemical shift. Magn Reson Med (1995) 5.73
The use of ribonuclease U2 in RNA sequence determination. Some corrections in the catalog of oligomers produced by ribonuclease T1 digestion of Escherichia coli 16S ribosomal RNA. J Mol Evol (1974) 5.26
Comparison of complete amino acid sequences and receptor-binding properties among 13 serotypes of hemagglutinins of influenza A viruses. Virology (1991) 4.85
Mutation in the structural gene for diphtheria toxin carried by temperate phage . Nat New Biol (1971) 4.67
Genetic analysis of blood pressure in spontaneously hypertensive rats. Jpn Circ J (1970) 4.59
Chloramphenicol-, dihydrostreptomycin-, and kanamycin-inactivating enzymes from multiple drug-resistant Escherichia coli carrying episome 'R'. Nature (1965) 4.53
PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes Dev (2001) 4.53
Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria. Cell (1998) 4.35
RNA-linked nascent DNA fragments in Escherichia coli. Proc Natl Acad Sci U S A (1972) 4.35
KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria. Cell (1994) 4.17
One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell. Cell (1978) 4.06
Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder. Proc Natl Acad Sci U S A (1995) 3.85
Hepatic specification of the gut endoderm in vitro: cell signaling and transcriptional control. Genes Dev (1996) 3.80
Diphtheria toxin and related proteins. I. Isolation and properties of mutant proteins serologically related to diphtheria toxin. J Biol Chem (1973) 3.78
Large voltage-induced magnetic anisotropy change in a few atomic layers of iron. Nat Nanotechnol (2009) 3.75
Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules. J Biol Chem (1997) 3.74
The DNA sequence of Bombyx mori fibroin gene including the 5' flanking, mRNA coding, entire intervening and fibroin protein coding regions. Cell (1979) 3.60
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2. Nat Genet (2001) 3.59
Proliferative activity of intratumoral CD8(+) T-lymphocytes as a prognostic factor in human renal cell carcinoma: clinicopathologic demonstration of antitumor immunity. Cancer Res (2001) 3.51
An immunological study of the diphtheria toxin molecule. Immunochemistry (1972) 3.48
Interferon beta prevents recurrence of hepatocellular carcinoma after complete resection or ablation of the primary tumor-A prospective randomized study of hepatitis C virus-related liver cancer. Hepatology (2000) 3.42
Mini-laparoscopic appendectomy using a needle loop retractor offers optimal cosmetic results. Surg Endosc (2004) 3.38
Analysis of a human DNA excision repair gene involved in group A xeroderma pigmentosum and containing a zinc-finger domain. Nature (1990) 3.23
Success and virulence in Toxoplasma as the result of sexual recombination between two distinct ancestries. Science (2001) 3.21
Structural analysis of the fibroin gene at the 5' end and its surrounding regions. Cell (1979) 3.16
Left-right asymmetry and kinesin superfamily protein KIF3A: new insights in determination of laterality and mesoderm induction by kif3A-/- mice analysis. J Cell Biol (1999) 3.14
Isolation from corynebacterium diphtheriae C7(beta) of bacterial mutants that produce toxin in medium with excess iron. Infect Immun (1977) 3.12
Accelerated transport and maturation of lysosomal alpha-galactosidase A in Fabry lymphoblasts by an enzyme inhibitor. Nat Med (1999) 3.11
Receptor specificity of influenza A viruses correlates with the agglutination of erythrocytes from different animal species. Virology (1997) 3.10
Evolutionary motif and its biological and structural significance. J Mol Evol (1997) 3.03
A new malformation syndrome of long palpebral fissures, large ears, depressed nasal tip, and skeletal anomalies associated with postnatal dwarfism and mental retardation. J Pediatr (1981) 2.97
Association of CD4+ T cell-dependent, interferon-gamma-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii. J Exp Med (1996) 2.97
Nucleotide sequence of the tobacco mosaic virus (tomato strain) genome and comparison with the common strain genome. J Biochem (1984) 2.93
Switch-based mechanism of kinesin motors. Nature (2001) 2.86
Complete nucleotide sequence and genetic organization of Aichi virus, a distinct member of the Picornaviridae associated with acute gastroenteritis in humans. J Virol (1998) 2.85
Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis. Proc Natl Acad Sci U S A (2000) 2.83
Segmented filamentous bacteria are indigenous intestinal bacteria that activate intraepithelial lymphocytes and induce MHC class II molecules and fucosyl asialo GM1 glycolipids on the small intestinal epithelial cells in the ex-germ-free mouse. Microbiol Immunol (1995) 2.83
Treatment of gastric fundal varices by balloon-occluded retrograde transvenous obliteration. J Gastroenterol Hepatol (1996) 2.81
Function of the 30 kd protein of tobacco mosaic virus: involvement in cell-to-cell movement and dispensability for replication. EMBO J (1987) 2.78
KIF3A/B: a heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport. J Cell Biol (1995) 2.77
Collagenase expression in the lungs of transgenic mice causes pulmonary emphysema. Cell (1992) 2.75
Reversible inhibition of protein import into the nucleus by wheat germ agglutinin injected into cultured cells. Exp Cell Res (1987) 2.75
Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy. Hepatology (1998) 2.67
Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice. Gastroenterology (1997) 2.67
A metalloproteinase from human rheumatoid synovial fibroblasts that digests connective tissue matrix components. Purification and characterization. J Biol Chem (1986) 2.65
Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes. Am J Pathol (2001) 2.63
Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma: a potential mechanism of lesion stabilization. Circulation (1998) 2.63
A human gene responsible for Zellweger syndrome that affects peroxisome assembly. Science (1992) 2.63
Expression of bacterial chloramphenicol acetyltransferase gene in tobacco plants mediated by TMV-RNA. EMBO J (1987) 2.61
In vitro mutagenesis of the putative replicase genes of tobacco mosaic virus. Nucleic Acids Res (1986) 2.58
Hop stunt viroid: molecular cloning and nucleotide sequence of the complete cDNA copy. Nucleic Acids Res (1983) 2.54
Close association of HLA-Bw51 with Behçet's disease. Arch Ophthalmol (1982) 2.51
Globoid cell leucodystrophy (Krabbe's disease): deficiency of galactocerebroside beta-galactosidase. Proc Natl Acad Sci U S A (1970) 2.48
Kinesin and dynein superfamily proteins in organelle transport and cell division. Curr Opin Cell Biol (1998) 2.46
Human intelectin is a novel soluble lectin that recognizes galactofuranose in carbohydrate chains of bacterial cell wall. J Biol Chem (2001) 2.45
Neurologic improvement after peripheral blood stem cell transplantation in POEMS syndrome. Neurology (2008) 2.45
KIF5C, a novel neuronal kinesin enriched in motor neurons. J Neurosci (2000) 2.43
KRN7000, a novel immunomodulator, and its antitumor activities. Oncol Res (1995) 2.43
Faithful transcription initiation of fibroin gene in a homologous cell-free system reveals an enhancing effect of 5' flanking sequence far upstream. Cell (1981) 2.42
Defect in synaptic vesicle precursor transport and neuronal cell death in KIF1A motor protein-deficient mice. J Cell Biol (1998) 2.40
Differences in sialic acid-galactose linkages in the chicken egg amnion and allantois influence human influenza virus receptor specificity and variant selection. J Virol (1997) 2.38
Genome-wide microRNA expression profiling in renal cell carcinoma: significant down-regulation of miR-141 and miR-200c. J Pathol (2008) 2.37
Binding properties of monoclonal antibody to the cytoplasmic domain of transferrin receptor. Cell Struct Funct (1988) 2.36
In vitro transcription of infectious RNAs from full-length cDNAs of tobacco mosaic virus. Proc Natl Acad Sci U S A (1986) 2.35
The relationship of preoperative magnetic resonance imaging findings and closed system drainage in the recurrence of chronic subdural hematoma. J Neurosurg (1997) 2.34
Daily walking combined with diet therapy is a useful means for obese NIDDM patients not only to reduce body weight but also to improve insulin sensitivity. Diabetes Care (1995) 2.33
Organization of rRNA genes in Mycobacterium bovis BCG. J Bacteriol (1987) 2.33
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in synovial fluids from patients with rheumatoid arthritis or osteoarthritis. Ann Rheum Dis (2000) 2.32
The enzymatic acetylation of chloramphenicol by the multiple drug-resistant Escherichia coli carrying R factor. J Biol Chem (1967) 2.31
The carboxyl third of tau is tightly bound to paired helical filaments. Neuron (1988) 2.31
The genes for silk fibroin in Bombyx mori. J Mol Biol (1972) 2.29
Inflammatory pseudotumor of the liver. Clinicopathologic study and review of the literature. Cancer (1990) 2.26
Expression and self-assembly of empty virus-like particles of hepatitis E virus. J Virol (1997) 2.25
Association of Trp64Arg mutation of the beta3-adrenergic-receptor with NIDDM and body weight gain. Diabetologia (1996) 2.22
Nucleotide sequence of cucumber pale fruit viroid: homology to hop stunt viroid. Nucleic Acids Res (1984) 2.22
Disease progression and hepatocellular carcinogenesis in patients with chronic viral hepatitis: a prospective observation of 2215 patients. J Hepatol (1998) 2.21
A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally. J Cell Biol (1994) 2.20
Inflammatory bowel disease-like enteritis and caecitis in a senescence accelerated mouse P1/Yit strain. Gut (1998) 2.20
Solubilization of antigen-antibody complexes: a new function of complement as a regulator of immune reactions. Prog Allergy (1980) 2.19
Application of a reverse transcription-PCR for identification and differentiation of Aichi virus, a new member of the Picornavirus family associated with gastroenteritis in humans. J Clin Microbiol (2000) 2.19
Restraining infarct expansion preserves left ventricular geometry and function after acute anteroapical infarction. Circulation (1999) 2.19
Factors predictive of survival among 337 patients with mesothelioma treated between 1984 and 1994 by the Cancer and Leukemia Group B. Chest (1998) 2.18
Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation. J Clin Invest (2000) 2.18
Heptakis(2,6-O-dimethyl)beta-cyclodextrin: a novel growth stimulant for Bordetella pertussis phase I. J Clin Microbiol (1983) 2.17
Expression of adult and fetal natural killer cell markers in sinonasal lymphomas. Blood (1994) 2.16
Validation study of the in vitro micronucleus test in a Chinese hamster lung cell line (CHL/IU). Mutagenesis (1999) 2.16
Pulmonary fibrosis in asbestos insulation workers with lung cancer: a radiological and histopathological evaluation. Br J Ind Med (1987) 2.14
Ribonuclease preparation for the base analysis of polyribonucleotides. Anal Biochem (1966) 2.11