Antonio Sica

Author PubWeight™ 171.89‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cancer-related inflammation. Nature 2008 34.21
2 The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol 2004 19.38
3 Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 2002 17.85
4 Macrophage activation and polarization. Front Biosci 2008 11.17
5 Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis 2009 7.55
6 Macrophages, innate immunity and cancer: balance, tolerance, and diversity. Curr Opin Immunol 2010 6.85
7 Macrophage polarization comes of age. Immunity 2005 5.67
8 Macrophage plasticity and polarization in tissue repair and remodelling. J Pathol 2012 4.30
9 Role of tumor-associated macrophages in tumor progression and invasion. Cancer Metastasis Rev 2006 4.02
10 The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages. Crit Rev Oncol Hematol 2007 3.95
11 A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation). Blood 2005 3.85
12 Regulation of the chemokine receptor CXCR4 by hypoxia. J Exp Med 2003 3.71
13 A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood "resident" monocytes, and embryonic macrophages suggests common functions and developmental relationships. Blood 2009 3.52
14 The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance. Immunol Rev 2008 3.33
15 Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB. Proc Natl Acad Sci U S A 2009 3.01
16 New vistas on macrophage differentiation and activation. Eur J Immunol 2007 2.99
17 p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance. Cancer Res 2006 2.76
18 Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxia inducible factor-1alpha. J Biol Chem 2005 2.40
19 Plasticity of macrophage function during tumor progression: regulation by distinct molecular mechanisms. J Immunol 2008 2.26
20 Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation. Hum Immunol 2009 2.19
21 Tumour-associated macrophages as a prototypic type II polarised phagocyte population: role in tumour progression. Eur J Cancer 2004 2.12
22 M2 macrophages phagocytose rituximab-opsonized leukemic targets more efficiently than m1 cells in vitro. J Immunol 2009 2.06
23 Pathways connecting inflammation and cancer. Curr Opin Genet Dev 2008 1.95
24 Human pancreatic islets produce and secrete MCP-1/CCL2: relevance in human islet transplantation. Diabetes 2002 1.84
25 Cellular and molecular pathways linking inflammation and cancer. Immunobiology 2009 1.78
26 Macrophage activation and polarization as an adaptive component of innate immunity. Adv Immunol 2013 1.67
27 Regulation of macrophage function in tumors: the multifaceted role of NF-kappaB. Blood 2009 1.59
28 Inflammation and cancer: breast cancer as a prototype. Breast 2007 1.52
29 Chemokines in the recruitment and shaping of the leukocyte infiltrate of tumors. Semin Cancer Biol 2004 1.43
30 Tumor promotion by tumor-associated macrophages. Adv Exp Med Biol 2007 1.31
31 Divergent effects of hypoxia on dendritic cell functions. Blood 2008 1.20
32 Infiltration of tumours by macrophages and dendritic cells: tumour-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Novartis Found Symp 2004 1.12
33 Retracted Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization. Immunity 2012 1.12
34 Expression of CD4 on human peripheral blood neutrophils. Blood 2003 1.07
35 MiR-146a and NF-κB1 regulate mast cell survival and T lymphocyte differentiation. Mol Cell Biol 2012 1.03
36 Mechanisms linking pathogens-associated inflammation and cancer. Cancer Lett 2010 1.03
37 Glutathione protects mice from lethal sepsis by limiting inflammation and potentiating host defense. J Infect Dis 2002 0.98
38 Cell-specific regulation of PTX3 by glucocorticoid hormones in hematopoietic and nonhematopoietic cells. J Biol Chem 2008 0.97
39 Hypoxia-mediated regulation of macrophage functions in pathophysiology. Int Immunol 2012 0.96
40 Enhanced interferon regulatory factor 3 binding to the interleukin-23p19 promoter correlates with enhanced interleukin-23 expression in systemic lupus erythematosus. Arthritis Rheum 2012 0.93
41 Linking inflammation reactions to cancer: novel targets for therapeutic strategies. Adv Exp Med Biol 2008 0.92
42 IL-10 limits production of pathogenic TNF by M1 myeloid cells through induction of nuclear NF-κB p50 member in Trypanosoma congolense infection-resistant C57BL/6 mice. Eur J Immunol 2011 0.90
43 Microenvironmental control of malignancy exerted by RNASET2, a widely conserved extracellular RNase. Proc Natl Acad Sci U S A 2010 0.90
44 Tumor-associated macrophages and dendritic cells as prototypic type II polarized myeloid populations. Tumori 2004 0.90
45 Angiostatin anti-angiogenesis requires IL-12: the innate immune system as a key target. J Transl Med 2009 0.87
46 Inactivation of junctional adhesion molecule-A enhances antitumoral immune response by promoting dendritic cell and T lymphocyte infiltration. Cancer Res 2010 0.84
47 Macrophages in cancer and infectious diseases: the 'good' and the 'bad'. Immunotherapy 2011 0.84
48 The p50 subunit of NF-κB orchestrates dendritic cell lifespan and activation of adaptive immunity. PLoS One 2012 0.81
49 Tolerance in intestinal inflammation and cancer. Curr Drug Targets 2008 0.76