Alcohol dehydrogenase-2*2 allele is associated with decreased prevalence of fetal alcohol syndrome in the mixed-ancestry population of the Western Cape Province, South Africa.

PubWeight™: 1.12‹?› | Rank: Top 10%

🔗 View Article (PMID 11781503)

Published in Alcohol Clin Exp Res on December 01, 2001

Authors

D L Viljoen1, L G Carr, T M Foroud, L Brooke, M Ramsay, T K Li

Author Affiliations

1: Foundation for Alcohol Related Research and Department of Human Genetics, Faculty of Health Sciences, University of the Witwaterstrand, National Health Laboratory Service, Johannesburg, South Africa. denisv@mail.saimr.wits.ac.za

Articles citing this

Maternal risk factors for fetal alcohol syndrome in the Western cape province of South Africa: a population-based study. Am J Public Health (2005) 2.17

Maternal risk factors for fetal alcohol spectrum disorders: not as simple as it might seem. Alcohol Res Health (2011) 1.36

Pdgfra protects against ethanol-induced craniofacial defects in a zebrafish model of FASD. Development (2013) 1.12

Fetal alcohol exposure and IQ at age 8: evidence from a population-based birth-cohort study. PLoS One (2012) 1.11

The teratogenic effects of prenatal ethanol exposure are exacerbated by Sonic Hedgehog or GLI2 haploinsufficiency in the mouse. PLoS One (2014) 1.05

Genetic and epigenetic insights into fetal alcohol spectrum disorders. Genome Med (2010) 1.03

Ethanol teratogenesis in five inbred strains of mice. Alcohol Clin Exp Res (2009) 1.02

Alcohol abuse in pregnant women: effects on the fetus and newborn, mode of action and maternal treatment. Int J Environ Res Public Health (2010) 0.95

Computational selection and prioritization of candidate genes for fetal alcohol syndrome. BMC Genomics (2007) 0.92

Fetal alcohol syndrome (FAS) in C57BL/6 mice detected through proteomics screening of the amniotic fluid. Birth Defects Res A Clin Mol Teratol (2008) 0.91

Focus on: epigenetics and fetal alcohol spectrum disorders. Alcohol Res Health (2011) 0.88

A panel of ancestry informative markers for the complex five-way admixed South African coloured population. PLoS One (2013) 0.85

Using the past to step forward: fetal alcohol syndrome in the Western Cape Province of South Africa. Am J Public Health (2005) 0.85

Protective effects of the alcohol dehydrogenase-ADH1B*3 allele on attention and behavior problems in adolescents exposed to alcohol during pregnancy. Neurotoxicol Teratol (2013) 0.82

High-throughput transcriptome sequencing identifies candidate genetic modifiers of vulnerability to fetal alcohol spectrum disorders. Alcohol Clin Exp Res (2014) 0.81

No effect of prenatal alcohol exposure on activity in three inbred strains of mice. Alcohol Alcohol (2008) 0.80

The Genetics of Fetal Alcohol Spectrum Disorders. Alcohol Clin Exp Res (2016) 0.80

The neuronal nitric oxide synthase (nNOS) gene and neuroprotection against alcohol toxicity. Cell Mol Neurobiol (2015) 0.77

Genetic absence of nNOS worsens fetal alcohol effects in mice. I: behavioral deficits. Alcohol Clin Exp Res (2015) 0.77

Importance of genetics in fetal alcohol effects: null mutation of the nNOS gene worsens alcohol-induced cerebellar neuronal losses and behavioral deficits. Neurotoxicology (2014) 0.76

Gene-environment interactions in development and disease. Wiley Interdiscip Rev Dev Biol (2016) 0.75

Maternal Phenylketonuria Collaborative Study (MPKUCS)--the 'outliers'. J Inherit Metab Dis (2004) 0.75

Articles by these authors

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet (2013) 9.46

Genome-wide search for genes affecting the risk for alcohol dependence. Am J Med Genet (1998) 6.04

Second dose of measles, mumps, and rubella vaccine: questionnaire survey of health professionals. BMJ (2001) 4.50

Alcoholism susceptibility loci: confirmation studies in a replicate sample and further mapping. Alcohol Clin Exp Res (2000) 3.42

Planning, registration, and implementation of an immunisation campaign against meningococcal serogroup C disease in the UK: a success story. Vaccine (2001) 3.36

A genome screen of maximum number of drinks as an alcoholism phenotype. Am J Med Genet (2000) 3.14

Animal models of alcoholism: neurobiology of high alcohol-drinking behavior in rodents. Crit Rev Neurobiol (1998) 3.07

Serogroup W135 meningococcal disease in Hajj pilgrims. Lancet (2001) 2.89

Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men. Am J Hum Genet (1991) 2.75

Interaction between the functional polymorphisms of the alcohol-metabolism genes in protection against alcoholism. Am J Hum Genet (1999) 2.73

Worldwide DNA sequence variation in a 10-kilobase noncoding region on human chromosome 22. Proc Natl Acad Sci U S A (2000) 2.67

Global patterns of human DNA sequence variation in a 10-kb region on chromosome 1. Mol Biol Evol (2001) 2.64

Effects of moderate alcohol consumption on the central nervous system. Alcohol Clin Exp Res (1998) 2.60

Anticoagulation in patients with atrial fibrillation. GPs not prepared for monitoring anticoagulation. BMJ (1993) 2.49

Distinct components of spatial learning revealed by prior training and NMDA receptor blockade. Nature (1995) 2.47

Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. The inactive ALDH2(2) allele is dominant. J Clin Invest (1989) 2.44

Epidemiology of fetal alcohol syndrome in a South African community in the Western Cape Province. Am J Public Health (2000) 2.30

Genetic polymorphism of human liver alcohol and aldehyde dehydrogenases, and their relationship to alcohol metabolism and alcoholism. Hepatology (1986) 2.20

Detection of influenza A(H3N2) virus in children with suspected mumps during winter 2014/15 in England. Euro Surveill (2015) 2.19

The rationale for the use of measles post-exposure prophylaxis in pregnant women: a review. J Obstet Gynaecol (2009) 2.04

Description of the Genetic Analysis Workshop 11 Collaborative Study on the Genetics of Alcoholism. Genet Epidemiol (1999) 2.01

Mechanism of action of camptothecin. Ann N Y Acad Sci (2000) 2.01

Hospital admissions attributable to rotavirus infection in England and Wales. J Infect Dis (1996) 1.98

The improving outlook for the small prematurely born infant. Dev Med Child Neurol (1973) 1.94

High polymorphism at the human melanocortin 1 receptor locus. Genetics (1999) 1.94

Polymorphism of ADH and ALDH genes among four ethnic groups in China and effects upon the risk for alcoholism. Alcohol Clin Exp Res (1997) 1.79

Maternal and fetal plasma levels of pyridoxal phosphate at term: adequacy of vitamin B6 supplementation during pregnancy. Am J Obstet Gynecol (1975) 1.78

UK measles outbreak in non-immune anthroposophic communities: the implications for the elimination of measles from Europe. Epidemiol Infect (2000) 1.77

Cloning and expression of the isopenicillin N synthetase gene from Penicillium chrysogenum. Gene (1986) 1.73

Ethanol self-infusion into the ventral tegmental area by alcohol-preferring rats. Alcohol (1995) 1.67

Evaluation of a nurse specialist anticoagulant service. Clin Lab Haematol (1997) 1.66

Ubiquitin/26S proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells. Cancer Res (2001) 1.63

Genetic anticipation and abnormal gender ratio at birth in familial primary pulmonary hypertension. Am J Respir Crit Care Med (1995) 1.60

Clamping breath alcohol concentration reduces experimental variance: application to the study of acute tolerance to alcohol and alcohol elimination rate. Alcohol Clin Exp Res (1998) 1.58

Intravenous dexmedetomidine as an adjunct for labor analgesia and cesarean delivery anesthesia in a parturient with a tethered spinal cord. Int J Obstet Anesth (2009) 1.56

Human pigmentation genetics: the difference is only skin deep. Bioessays (1998) 1.56

Selective breeding for high and low alcohol preference in mice. Behav Genet (1999) 1.51

A physiologically-based pharmacokinetic (PBPK) model for alcohol facilitates rapid BrAC clamping. Alcohol Clin Exp Res (1999) 1.50

Guidelines for anticoagulation. BMJ (1994) 1.50

Vitamin B6 metabolism in chronic alcohol abuse. Pyridoxal phosphate levels in plasma and the effects of acetaldehyde on pyridoxal phosphate synthesis and degradation in human erythrocytes. J Clin Invest (1974) 1.49

A randomized trial comparing prednisone with antithymocyte globulin/prednisone as an initial systemic therapy for moderately severe acute graft-versus-host disease. Biol Blood Marrow Transplant (2000) 1.48

Sequelae of early steroid administration to the newborn infant. Pediatrics (1974) 1.48

Quantitative trait loci analysis of human event-related brain potentials: P3 voltage. Electroencephalogr Clin Neurophysiol (1998) 1.43

Involvement of nicotinic receptors in alcohol self-administration. Alcohol Clin Exp Res (2000) 1.43

Alcohol stimulates the release of dopamine and serotonin in the nucleus accumbens. Alcohol (1992) 1.43

Effects of scheduled access on ethanol intake by the alcohol-preferring (P) line of rats. Alcohol (1986) 1.42

Effects of concurrent access to multiple ethanol concentrations and repeated deprivations on alcohol intake of alcohol-preferring rats. Alcohol Clin Exp Res (2001) 1.42

Comparison of alcohol-preferring (P) and nonpreferring (NP) rats on tests of anxiety and for the anxiolytic effects of ethanol. Alcohol (1993) 1.41

Mumps surveillance in England and Wales supports introduction of two dose vaccination schedule. Commun Dis Rep CDR Rev (1997) 1.40

Low frequency of the ADH2*2 allele among Atayal natives of Taiwan with alcohol use disorders. Alcohol Clin Exp Res (1994) 1.38

Epidural injection does cause an increase in CSF pressure. Anesth Analg (1991) 1.38

A quantitative trait locus for alcohol consumption in selectively bred rat lines. Alcohol Clin Exp Res (1998) 1.37

Clinical implications for four drugs of the DSM-IV distinction between substance dependence with and without a physiological component. Am J Psychiatry (1999) 1.37

Research advances in ethanol metabolism. Pathol Biol (Paris) (2001) 1.37

Genotyping of human alcohol dehydrogenases at the ADH2 and ADH3 loci following DNA sequence amplification. Genomics (1988) 1.37

Progress toward a voluntary oral consumption model of alcoholism. Drug Alcohol Depend (1980) 1.36

Genomic screen for QTLs underlying alcohol consumption in the P and NP rat lines. Mamm Genome (1998) 1.35

Association of the ADH2*2 allele with reduced ethanol consumption in Jewish men in Israel: a pilot study. J Stud Alcohol (1998) 1.35

Direct measurement of active transport systems for alanine in freshly isolated rat liver cells. Biochem Biophys Res Commun (1977) 1.33

Molecular epidemiology of human group A rotavirus infections in the United Kingdom between 1995 and 1998. J Clin Microbiol (2000) 1.33

Alcohol deprivation effect is prolonged in the alcohol preferring (P) rat after repeated deprivations. Alcohol Clin Exp Res (2000) 1.33

Serum ionized calcium during bed rest in fracture patients and normal men. Metabolism (1972) 1.32

Clinical and molecular characterization of lipoid proteinosis in Namaqualand, South Africa. Br J Dermatol (2004) 1.32

The expression of an alcohol deprivation effect in the high-alcohol-drinking replicate rat lines is dependent on repeated deprivations. Alcohol Clin Exp Res (2000) 1.29

An A/G polymorphism in the promoter of mitochondrial aldehyde dehydrogenase (ALDH2): effects of the sequence variant on transcription factor binding and promoter strength. Alcohol Clin Exp Res (1999) 1.29

An evidence synthesis approach to estimating Hepatitis C prevalence in England and Wales. Stat Methods Med Res (2008) 1.28

Defining alcohol-related phenotypes in humans. The Collaborative Study on the Genetics of Alcoholism. Alcohol Res Health (2002) 1.27

Increased vulnerability to nicotine self-administration and relapse in alcohol-naive offspring of rats selectively bred for high alcohol intake. J Neurosci (2006) 1.26

Involvement of acetaldehyde for full protection against alcoholism by homozygosity of the variant allele of mitochondrial aldehyde dehydrogenase gene in Asians. Pharmacogenetics (1999) 1.25

Alcohol dehydrogenase polymorphisms influence alcohol-elimination rates in a male Jewish population. Alcohol Clin Exp Res (2004) 1.25

Human liver alcohol dehydrogenase: purification and kinetic characterization of the beta 2 beta 2, beta 2 beta 1, alpha beta 2, and beta 2 gamma 1 "Oriental" isoenzymes. Biochemistry (1984) 1.25

An intragenic deletion of the P gene is the common mutation causing tyrosinase-positive oculocutaneous albinism in southern African Negroids. Am J Hum Genet (1995) 1.24

Five hepatitis B outbreaks in care homes in the UK associated with deficiencies in infection control practice in blood glucose monitoring. Epidemiol Infect (2010) 1.24

Rufous oculocutaneous albinism in southern African Blacks is caused by mutations in the TYRP1 gene. Am J Hum Genet (1997) 1.23

Isolation of pi-alcohol dehydrogenase of human liver: is it a determinant of alcoholism? Proc Natl Acad Sci U S A (1977) 1.22

Prenatal alcohol exposure alters the patterns of facial asymmetry. Alcohol (2010) 1.21

Consumption of sweet, salty, sour, and bitter solutions by selectively bred alcohol-preferring and alcohol-nonpreferring lines of rats. Alcohol Clin Exp Res (1994) 1.20

Human DNA sequence variation in a 6.6-kb region containing the melanocortin 1 receptor promoter. Genetics (2001) 1.20

Oculomotor control in asymptomatic and recently diagnosed individuals with the genetic marker for Huntington's disease. Vision Res (2004) 1.20

Cardiovascular risk profile of patients with psoriatic arthritis compared to controls--the role of inflammation. Rheumatology (Oxford) (2008) 1.20

Polymorphism of alcohol and aldehyde dehydrogenase genes and alcoholic cirrhosis in Chinese patients. Hepatology (1994) 1.19

Blocking GABA(A) receptors in the anterior ventral tegmental area attenuates ethanol intake of the alcohol-preferring P rat. Psychopharmacology (Berl) (1998) 1.19

Long and short alcohol deprivation: effects on AA and P alcohol-preferring rats. Alcohol (1990) 1.19

Identification and characterization of an immunophilin expressed during the clonal expansion phase of adipocyte differentiation. Proc Natl Acad Sci U S A (1995) 1.19

Taste preferences in rat lines selected for low and high alcohol consumption. Alcohol (1992) 1.18

Long-term sequelae of neonatal meningitis. Dev Med Child Neurol (1974) 1.18

Genetic factors in alcohol metabolism and alcoholism. Semin Liver Dis (1993) 1.18

Invasive meningococcal disease among university undergraduates: association with universities providing relatively large amounts of catered hall accommodation. Epidemiol Infect (1999) 1.17

Exposure of healthcare workers in England, Wales, and Northern Ireland to bloodborne viruses between July 1997 and June 2000: analysis of surveillance data. BMJ (2001) 1.17

Pyridoxal 5'-phosphate in plasma: source, protein-binding, and cellular transport. J Lab Clin Med (1974) 1.17

Densities of dopamine D2 receptors are reduced in CNS regions of alcohol-preferring P rats. Alcohol (1993) 1.17

Tetany: quantitative interrelationships between calcium and alkalosis. Am J Physiol (1975) 1.17

Alcohol and aldehyde dehydrogenase polymorphisms and alcoholism. Behav Genet (1993) 1.17

Induction of dependence on ethanol by free-choice drinking in alcohol-preferring rats. Pharmacol Biochem Behav (1982) 1.16

Ameloblastoma in the Hong Kong Chinese. Part 2: systematic review and radiological presentation. Dentomaxillofac Radiol (2004) 1.16

A preliminary study of acute responses to clamped alcohol concentration and family history of alcoholism. Alcohol Clin Exp Res (1999) 1.15

Differences in response to the aversive properties of ethanol in rats selectively bred for oral ethanol preference. Pharmacol Biochem Behav (1988) 1.15

Different sensitivities to ethanol in alcohol-preferring and -nonpreferring rats. Pharmacol Biochem Behav (1982) 1.15