Published in Cancer Res on January 01, 2002
Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene. Am J Hum Genet (2003) 1.80
Genomic deletions of MSH2 and MLH1 in colorectal cancer families detected by a novel mutation detection approach. Br J Cancer (2002) 1.65
Regulation of the human MSH6 gene by the Sp1 transcription factor and alteration of promoter activity and expression by polymorphisms. Mol Cell Biol (2003) 1.05
Discovery of the BMPR1A promoter and germline mutations that cause juvenile polyposis. Hum Mol Genet (2010) 1.00
The association between genetic variants in hMLH1 and hMSH2 and the development of sporadic colorectal cancer in the Danish population. BMC Med Genet (2008) 0.97
Three novel missense germline mutations in different exons of MSH6 gene in Chinese hereditary non-polyposis colorectal cancer families. World J Gastroenterol (2007) 0.96
Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts. Ulster Med J (2008) 0.93
MLH1 promoter germline-methylation in selected probands of Chinese hereditary non-polyposis colorectal cancer families. World J Gastroenterol (2008) 0.85
Differential MSH2 promoter methylation in blood cells of Neurofibromatosis type 1 (NF1) patients. Eur J Hum Genet (2010) 0.85
Detection of germline mutations of hMLH1 and hMSH2 based on cDNA sequencing in China. World J Gastroenterol (2005) 0.79
Characteristics of hereditary nonpolyposis colorectal cancer patients with double primary cancers in endometrium and colorectum. Obstet Gynecol Sci (2015) 0.78
Polymorphisms of mismatch repair gene hMLH1 and hMSH2 and risk of gastric cancer in a Chinese population. Oncol Lett (2011) 0.78
Haplotype defined by the MLH1-93G/A polymorphism is associated with MLH1 promoter hypermethylation in sporadic colorectal cancers. BMC Res Notes (2014) 0.77
Association between MutL homolog 1 polymorphisms and the risk of colorectal cancer: a meta-analysis. J Cancer Res Clin Oncol (2015) 0.76
The hMLH1 -93G>A Polymorphism and Risk of Ovarian Cancer in the Chinese Population. PLoS One (2015) 0.75
Nationwide cancer incidence in Korea, 1999~2001; first result using the national cancer incidence database. Cancer Res Treat (2005) 11.27
Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease. Nat Med (2010) 4.45
Prolongation of the period between biopsy and EMR can influence the nonlifting sign in endoscopically resectable colorectal cancers. Gastrointest Endosc (2008) 3.05
2002 annual report of the Korea Central Cancer Registry: based on registered data from 139 hospitals. Cancer Res Treat (2004) 2.90
Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function. Proc Natl Acad Sci U S A (2010) 1.81
CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity. Proc Natl Acad Sci U S A (2009) 1.64
Clinical parameters predicting pathologic tumor response after preoperative chemoradiotherapy for rectal cancer. Int J Radiat Oncol Biol Phys (2007) 1.53
Optimal surgery time after preoperative chemoradiotherapy for locally advanced rectal cancers. Ann Surg (2008) 1.51
Neonatal hair nicotine levels and fetal exposure to paternal smoking at home. Am J Epidemiol (2008) 1.48
Feasibility of laparoscopic techniques as the surgical approach of choice for primary colorectal cancer: an analysis of 570 consecutive cases. Surg Endosc (2008) 1.48
Gastric cancer patients at high-risk of having synchronous cancer. World J Gastroenterol (2006) 1.44
Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage. Proc Natl Acad Sci U S A (2011) 1.42
Relative and absolute risks of cigarette smoking on major histologic types of lung cancer in Korean men. Cancer Epidemiol Biomarkers Prev (2005) 1.41
Identification of genes with differential expression in acquired drug-resistant gastric cancer cells using high-density oligonucleotide microarrays. Clin Cancer Res (2004) 1.37
Establishment and characterization of four human hepatocellular carcinoma cell lines containing hepatitis B virus DNA. World J Gastroenterol (1999) 1.34
Comparison of 5-fluorouracil/leucovorin and capecitabine in preoperative chemoradiotherapy for locally advanced rectal cancer. Int J Radiat Oncol Biol Phys (2006) 1.33
Identification of novel cellular targets in biliary tract cancers using global gene expression technology. Am J Pathol (2003) 1.33
Promoter hypermethylation downregulates RUNX3 gene expression in colorectal cancer cell lines. Oncogene (2004) 1.24
Lateral lymph node metastasis is a major cause of locoregional recurrence in rectal cancer treated with preoperative chemoradiotherapy and curative resection. Ann Surg Oncol (2007) 1.23
Germline mutations of the MYH gene in Korean patients with multiple colorectal adenomas. Int J Colorectal Dis (2007) 1.23
Mutational analysis of BRAF and K-ras in gastric cancers: absence of BRAF mutations in gastric cancers. Hum Genet (2003) 1.21
Down-regulation of mitochondrial F1F0-ATP synthase in human colon cancer cells with induced 5-fluorouracil resistance. Cancer Res (2005) 1.20
Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss. Nat Neurosci (2013) 1.18
A naturally derived gastric cancer cell line shows latency I Epstein-Barr virus infection closely resembling EBV-associated gastric cancer. Virology (2004) 1.15
Microarray gene expression profiling for predicting complete response to preoperative chemoradiotherapy in patients with advanced rectal cancer. Dis Colon Rectum (2007) 1.13
Biology of SNU cell lines. Cancer Res Treat (2005) 1.11
Notch1 counteracts WNT/β-catenin signaling through chromatin modification in colorectal cancer. J Clin Invest (2012) 1.10
Influence of preoperative chemoradiotherapy on the number of lymph nodes retrieved in rectal cancer. Ann Surg (2010) 1.10
Targeted sequencing of cancer-related genes in colorectal cancer using next-generation sequencing. PLoS One (2013) 1.10
Analysis of KRAS, BRAF, PTEN, IGF1R, EGFR intron 1 CA status in both primary tumors and paired metastases in determining benefit from cetuximab therapy in colon cancer. Cancer Chemother Pharmacol (2011) 1.09
Decreased pyruvate kinase M2 activity linked to cisplatin resistance in human gastric carcinoma cell lines. Int J Cancer (2004) 1.08
The AAA+ ATPase Thorase regulates AMPA receptor-dependent synaptic plasticity and behavior. Cell (2011) 1.07
Correlation between hypermethylation of the RASSF2A promoter and K-ras/BRAF mutations in microsatellite-stable colorectal cancers. Int J Cancer (2007) 1.04
Upregulation of glycolytic enzymes in proteins secreted from human colon cancer cells with 5-fluorouracil resistance. Electrophoresis (2009) 1.03
A sensitive enzyme immunoassay for measuring cotinine in passive smokers. Clin Chim Acta (2010) 1.01
Metabotropic glutamate receptor 4 expression in colorectal carcinoma and its prognostic significance. Clin Cancer Res (2005) 0.98
The E-cadherin -347G->GA promoter polymorphism and its effect on transcriptional regulation. Carcinogenesis (2004) 0.98
Microsatellite instability testing in Korean patients with colorectal cancer. Fam Cancer (2012) 0.97
Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer. Int J Cancer (2012) 0.97
Usefulness of magnetic resonance volumetric evaluation in predicting response to preoperative concurrent chemoradiotherapy in patients with resectable rectal cancer. Int J Radiat Oncol Biol Phys (2005) 0.96
Prognostic significance of microsatellite instability in sporadic colorectal cancer. Int J Colorectal Dis (2004) 0.96
Genetic alterations of the TGF-beta signaling pathway in colorectal cancer cell lines: a novel mutation in Smad3 associated with the inactivation of TGF-beta-induced transcriptional activation. Cancer Lett (2006) 0.96
KRAS mutation is associated with worse prognosis in stage III or high-risk stage II colon cancer patients treated with adjuvant FOLFOX. Ann Surg Oncol (2014) 0.96
Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers. Carcinogenesis (2010) 0.96
Bax, a predictive marker for therapeutic response to preoperative chemoradiotherapy in patients with rectal carcinoma. Hum Pathol (2005) 0.96
A functional polymorphism (-347 G-->GA) in the E-cadherin gene is associated with colorectal cancer. Carcinogenesis (2004) 0.95
Is T classification still correlated with lymph node status after preoperative chemoradiotherapy for rectal cancer? Cancer (2006) 0.95
DNA microarray analysis of the correlation between gene expression patterns and acquired resistance to 5-FU/cisplatin in gastric cancer. Biochem Biophys Res Commun (2004) 0.94
2001 annual report of the Korea Central Cancer Registry: based on registered data from 134 hospitals. Cancer Res Treat (2004) 0.94
Atypical endoscopic features can be associated with metastasis in rectal carcinoid tumors. Surg Endosc (2008) 0.94
Novel polymorphisms in the SUV39H2 histone methyltransferase and the risk of lung cancer. Carcinogenesis (2006) 0.93
Hereditary nonpolyposis colorectal cancer in endometrial cancer patients. Int J Cancer (2008) 0.92
Oligonucleotide microarray analysis of distinct gene expression patterns in colorectal cancer tissues harboring BRAF and K-ras mutations. Carcinogenesis (2005) 0.92
Increased expression of metallothionein is associated with irinotecan resistance in gastric cancer. Cancer Res (2004) 0.92
Germline mutations of BRCA1 and BRCA2 in Korean breast and/or ovarian cancer families. Hum Mutat (2002) 0.92
Metabotropic glutamate receptor 4-mediated 5-Fluorouracil resistance in a human colon cancer cell line. Clin Cancer Res (2004) 0.91
Prevalence of gastric and duodenal polyps and risk factors for duodenal neoplasm in korean patients with familial adenomatous polyposis. Gut Liver (2011) 0.91
Development and applications of a beta-catenin oligonucleotide microarray: beta-catenin mutations are dominantly found in the proximal colon cancers with microsatellite instability. Clin Cancer Res (2003) 0.91
Biochemical analysis of six genetic variants of error-prone human DNA polymerase ι involved in translesion DNA synthesis. Chem Res Toxicol (2014) 0.90
Germline mutations in MLH1, MSH2 and MSH6 in Korean hereditary non-polyposis colorectal cancer families. Hum Mutat (2004) 0.90
Selection of cap size in endoscopic submucosal resection with cap aspiration for rectal carcinoid tumors. J Laparoendosc Adv Surg Tech A (2008) 0.90
Does t3 subdivision correlate with nodal or distant metastasis in colorectal cancer? J Korean Soc Coloproctol (2012) 0.90
Pharmacogenetic analysis of adjuvant FOLFOX for Korean patients with colon cancer. Cancer Chemother Pharmacol (2013) 0.90
A TP53-truncating germline mutation (E287X) in a family with characteristics of both hereditary diffuse gastric cancer and Li-Fraumeni syndrome. J Hum Genet (2004) 0.89
Single immunochemical fecal occult blood test for detection of colorectal neoplasia. Cancer Res Treat (2005) 0.89
Notch signaling promotes the generation of EphrinB1-positive intestinal epithelial cells. Gastroenterology (2009) 0.89
Mutation spectrum of the APC gene in 83 Korean FAP families. Hum Mutat (2005) 0.89
Depth of mesorectal extension has prognostic significance in patients with T3 rectal cancer. Dis Colon Rectum (2012) 0.88
RNA editing in RHOQ promotes invasion potential in colorectal cancer. J Exp Med (2014) 0.88
Robust microsatellite instability (MSI) analysis by denaturing high-performance liquid chromatography (DHPLC). J Hum Genet (2003) 0.88
Preoperative chemoradiation with irinotecan and capecitabine in patients with locally advanced resectable rectal cancer: long-term results of a Phase II study. Int J Radiat Oncol Biol Phys (2010) 0.88
Oligonucleotide microarray-based mutation detection of the K-ras gene in colorectal cancers with use of competitive DNA hybridization. Clin Chem (2004) 0.88
Promoter hypermethylation and loss of CD133 gene expression in colorectal cancers. World J Gastroenterol (2010) 0.88
Clinical features of colorectal cancer detected by the national cancer screening program. J Korean Soc Coloproctol (2010) 0.87
Comparison of the belly board device method and the distended bladder method for reducing irradiated small bowel volumes in preoperative radiotherapy of rectal cancer patients. Int J Radiat Oncol Biol Phys (2005) 0.87
Evaluation of calgranulin B in stools from the patients with colorectal cancer. Dis Colon Rectum (2008) 0.86
Effectiveness of proactive Quitline service and predictors of successful smoking cessation: findings from a preliminary study of Quitline service for smoking cessation in Korea. J Korean Med Sci (2008) 0.86
Biochemical characterization of eight genetic variants of human DNA polymerase κ involved in error-free bypass across bulky N(2)-guanyl DNA adducts. Chem Res Toxicol (2014) 0.85
Development and applications of a BRAF oligonucleotide microarray. J Mol Diagn (2007) 0.85
Promoter hypermethylation of the ADAM23 gene in colorectal cancer cell lines and cancer tissues. Int J Cancer (2009) 0.85
The comparison of two smoking biomarkers in various biological samples. Clin Chim Acta (2007) 0.85
Promoter hypermethylation and silencing of CHFR mitotic stress checkpoint gene in human gastric cancers. Oncol Rep (2004) 0.85
Tumor budding as an indicator of isolated tumor cells in lymph nodes from patients with node-negative colorectal cancer. Dis Colon Rectum (2005) 0.85
Microsatellite instability and mutations in DNA mismatch repair genes in sporadic colorectal cancers. Dis Colon Rectum (2003) 0.85
Survival paradox between stage IIB/C (T4N0) and stage IIIA (T1-2N1) colon cancer. Ann Surg Oncol (2014) 0.85
The impact of heavy smoking on anastomotic leakage and stricture after low anterior resection in rectal cancer patients. World J Surg (2011) 0.85
The hOGG1 Ser326Cys polymorphism is not associated with colorectal cancer risk. J Epidemiol (2007) 0.84
A Novel IVS2-1G>A mutation causes aberrant splicing of the HRPT2 gene in a family with hyperparathyroidism-jaw tumor syndrome. J Clin Endocrinol Metab (2004) 0.83
Establishment and characterization of six human gastric carcinoma cell lines, including one naturally infected with Epstein-Barr virus. Cell Oncol (Dordr) (2012) 0.83
Tobacco: deadly in any form or disguise. Lancet (2006) 0.83
Identification of mitochondrial FoF1-ATP synthase involved in liver metastasis of colorectal cancer. Cancer Sci (2007) 0.83
Promoter hypomethylation and reactivation of MAGE-A1 and MAGE-A3 genes in colorectal cancer cell lines and cancer tissues. World J Gastroenterol (2006) 0.83
Job loss and reemployment after a cancer diagnosis in Koreans - a prospective cohort study. Psychooncology (2007) 0.83
Regulation of MDK expression in human cancer cells modulates sensitivities to various anticancer drugs: MDK overexpression confers to a multi-drug resistance. Cancer Lett (2006) 0.83
Isolated tumor cells in lymph nodes are not a prognostic marker for patients with stage I and stage II colorectal cancer. J Surg Oncol (2006) 0.83
Risk factors for anastomotic leakage after resection for rectal cancer. Hepatogastroenterology (2006) 0.82
DNA microarrays on a dendron-modified surface improve significantly the detection of single nucleotide variations in the p53 gene. Nucleic Acids Res (2005) 0.82