Published in Development on January 01, 2002
C. elegans dauer formation and the molecular basis of plasticity. Genes Dev (2008) 3.20
Dauer. WormBook (2007) 2.87
A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling. Proc Natl Acad Sci U S A (2007) 2.50
A potent dauer pheromone component in Caenorhabditis elegans that acts synergistically with other components. Proc Natl Acad Sci U S A (2008) 2.35
Fatty acid desaturation links germ cell loss to longevity through NHR-80/HNF4 in C. elegans. PLoS Biol (2011) 2.32
A genetic program promotes C. elegans longevity at cold temperatures via a thermosensitive TRP channel. Cell (2013) 2.25
Regulation of the longevity response to temperature by thermosensory neurons in Caenorhabditis elegans. Curr Biol (2009) 2.22
Genetics of aging in Caenorhabditis elegans. PLoS Genet (2007) 1.97
Biosynthesis of the Caenorhabditis elegans dauer pheromone. Proc Natl Acad Sci U S A (2009) 1.96
Neural and molecular dissection of a C. elegans sensory circuit that regulates fat and feeding. Cell Metab (2008) 1.93
Nuclear hormone receptor regulation of microRNAs controls developmental progression. Science (2009) 1.69
Running hot and cold: behavioral strategies, neural circuits, and the molecular machinery for thermotaxis in C. elegans and Drosophila. Genes Dev (2010) 1.63
Comparative metabolomics reveals endogenous ligands of DAF-12, a nuclear hormone receptor, regulating C. elegans development and lifespan. Cell Metab (2014) 1.60
A novel nuclear receptor/coregulator complex controls C. elegans lipid metabolism, larval development, and aging. Genes Dev (2004) 1.57
Reproduction, fat metabolism, and life span: what is the connection? Cell Metab (2013) 1.51
Identification of C. elegans DAF-12-binding sites, response elements, and target genes. Genes Dev (2004) 1.39
Coordinating growth and maturation - insights from Drosophila. Curr Biol (2011) 1.38
Positive selection of Caenorhabditis elegans mutants with increased stress resistance and longevity. Genetics (2003) 1.37
Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16. PLoS Biol (2004) 1.34
Neuroendocrine regulation of Drosophila metamorphosis requires TGFbeta/Activin signaling. Development (2011) 1.33
The somatic reproductive tissues of C. elegans promote longevity through steroid hormone signaling. PLoS Biol (2010) 1.29
A transcription elongation factor that links signals from the reproductive system to lifespan extension in Caenorhabditis elegans. PLoS Genet (2009) 1.27
Two membrane-associated tyrosine phosphatase homologs potentiate C. elegans AKT-1/PKB signaling. PLoS Genet (2006) 1.20
Regulation of signaling genes by TGFbeta during entry into dauer diapause in C. elegans. BMC Dev Biol (2004) 1.20
EAK-7 controls development and life span by regulating nuclear DAF-16/FoxO activity. Cell Metab (2010) 1.10
Mutations of a Drosophila NPC1 gene confer sterol and ecdysone metabolic defects. Genetics (2005) 1.09
Sterol regulation of metabolism, homeostasis, and development. Annu Rev Biochem (2011) 1.08
Nuclear hormone receptors in nematodes: evolution and function. Mol Cell Endocrinol (2010) 1.08
A novel 3-hydroxysteroid dehydrogenase that regulates reproductive development and longevity. PLoS Biol (2012) 1.07
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins. Proc Natl Acad Sci U S A (2004) 1.07
Caenorhabditis elegans nuclear receptors: insights into life traits. Trends Endocrinol Metab (2008) 1.05
The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity. Aging Cell (2011) 1.03
DAF-12 regulates a connected network of genes to ensure robust developmental decisions. PLoS Genet (2011) 1.02
RNAseq analysis of the parasitic nematode Strongyloides stercoralis reveals divergent regulation of canonical dauer pathways. PLoS Negl Trop Dis (2012) 1.00
Transcriptomes and pathways associated with infectivity, survival and immunogenicity in Brugia malayi L3. BMC Genomics (2009) 0.99
Functional divergence of dafachronic acid pathways in the control of C. elegans development and lifespan. Dev Biol (2010) 0.98
The dauer hypothesis and the evolution of parasitism: 20 years on and still going strong. Int J Parasitol (2013) 0.96
A Caenorhabditis elegans developmental decision requires insulin signaling-mediated neuron-intestine communication. Development (2014) 0.96
Hormonal signal amplification mediates environmental conditions during development and controls an irreversible commitment to adulthood. PLoS Biol (2012) 0.94
The C. elegans developmental timing protein LIN-42 regulates diapause in response to environmental cues. Development (2010) 0.94
The garlic constituent diallyl trisulfide increases the lifespan of C. elegans via skn-1 activation. Exp Gerontol (2011) 0.93
Regulation of longevity by the reproductive system. Exp Gerontol (2012) 0.92
Identification of two epoxide hydrolases in Caenorhabditis elegans that metabolize mammalian lipid signaling molecules. Arch Biochem Biophys (2008) 0.92
Caenorhabditis elegans EAK-3 inhibits dauer arrest via nonautonomous regulation of nuclear DAF-16/FoxO activity. Dev Biol (2008) 0.91
Public and private mechanisms of life extension in Caenorhabditis elegans. Mol Genet Genomics (2007) 0.89
Steroids as central regulators of organismal development and lifespan. PLoS Biol (2012) 0.89
Environmental Temperature Differentially Modulates C. elegans Longevity through a Thermosensitive TRP Channel. Cell Rep (2015) 0.88
RNA-Seq reveals early distinctions and late convergence of gene expression between diapause and quiescence in the Asian tiger mosquito, Aedes albopictus. J Exp Biol (2013) 0.87
Variation in NPC1, the gene encoding Niemann-Pick C1, a protein involved in intracellular cholesterol transport, is associated with Alzheimer disease and/or aging in the Polish population. Neurosci Lett (2008) 0.86
Identification of late larval stage developmental checkpoints in Caenorhabditis elegans regulated by insulin/IGF and steroid hormone signaling pathways. PLoS Genet (2014) 0.86
New genetic regulators question relevance of abundant yolk protein production in C. elegans. Sci Rep (2015) 0.84
Nuclear hormone receptor regulation of microRNAs controls innate immune responses in C. elegans. PLoS Pathog (2013) 0.84
Unexpected role for dosage compensation in the control of dauer arrest, insulin-like signaling, and FoxO transcription factor activity in Caenorhabditis elegans. Genetics (2013) 0.83
cGMP and NHR signaling co-regulate expression of insulin-like peptides and developmental activation of infective larvae in Strongyloides stercoralis. PLoS Pathog (2014) 0.83
Dafadine inhibits DAF-9 to promote dauer formation and longevity of Caenorhabditis elegans. Nat Chem Biol (2011) 0.81
Caenorhabditis Elegans Mutants Predict Regulation of Fatty Acids and Endocannabinoids by the CYP-35A Gene Family. Front Pharmacol (2011) 0.81
Heat shock factor-1 intertwines insulin/IGF-1, TGF-β and cGMP signaling to control development and aging. BMC Dev Biol (2012) 0.81
Developmental plasticity and the evolution of parasitism in an unusual nematode, Parastrongyloides trichosuri. Evodevo (2012) 0.80
daf-31 encodes the catalytic subunit of N alpha-acetyltransferase that regulates Caenorhabditis elegans development, metabolism and adult lifespan. PLoS Genet (2014) 0.80
Regulation of Caenorhabditis elegans male mate searching behavior by the nuclear receptor DAF-12. Genetics (2008) 0.80
Comparative endocrinology of aging and longevity regulation. Front Endocrinol (Lausanne) (2011) 0.79
Regulation of Life Cycle Checkpoints and Developmental Activation of Infective Larvae in Strongyloides stercoralis by Dafachronic Acid. PLoS Pathog (2016) 0.79
Influence of steroid hormone signaling on life span control by Caenorhabditis elegans insulin-like signaling. G3 (Bethesda) (2013) 0.78
dbl-1/TGF-β and daf-12/NHR Signaling Mediate Cell-Nonautonomous Effects of daf-16/FOXO on Starvation-Induced Developmental Arrest. PLoS Genet (2015) 0.78
Photoperiodic Diapause and the Establishment of Aedes albopictus (Diptera: Culicidae) in North America. J Med Entomol (2016) 0.78
A functional genomic screen for evolutionarily conserved genes required for lifespan and immunity in germline-deficient C. elegans. PLoS One (2014) 0.78
The impact of mitochondrial oxidative stress on bile acid-like molecules in C. elegans provides a new perspective on human metabolic diseases. Worm (2013) 0.78
Function of the PHA-4/FOXA transcription factor during C. elegans post-embryonic development. BMC Dev Biol (2008) 0.78
No Significant Increase in the Δ4- and Δ7-Dafachronic Acid Concentration in the Long-Lived glp-1 Mutant, nor in the Mutants Defective in Dauer Formation. G3 (Bethesda) (2015) 0.77
Noise propagation with interlinked feed-forward pathways. Sci Rep (2016) 0.77
Integration of carbohydrate metabolism and redox state controls dauer larva formation in Caenorhabditis elegans. Nat Commun (2015) 0.77
Combined informatic and expression screen identifies the novel DAF-16 target HLH-13. Dev Biol (2008) 0.77
C. elegans NIMA-related kinases NEKL-2 and NEKL-3 are required for the completion of molting. Dev Biol (2014) 0.76
Genetic regulation of arrested development in nematodes: are age-1 and daf-gene orthologs present in Dictyocaulus viviparus? Parasitol Res (2007) 0.76
Genomes of Strongylocentrotus franciscanus and Lytechinus variegatus: are there any genomic explanations for the two order of magnitude difference in the lifespan of sea urchins? Aging (Albany NY) (2016) 0.76
CEH-28 activates dbl-1 expression and TGF-β signaling in the C. elegans M4 neuron. Dev Biol (2014) 0.76
The Role of Dafachronic Acid Signaling in Development and Longevity in Caenorhabditis elegans: Digging Deeper Using Cutting-Edge Analytical Chemistry. Front Endocrinol (Lausanne) (2016) 0.75
Nuclear receptors: emerging drug targets for parasitic diseases. J Clin Invest (2017) 0.75
A photocleavable masked nuclear-receptor ligand enables temporal control of C. elegans development. Angew Chem Int Ed Engl (2014) 0.75
Conserved Ankyrin Repeat Proteins and Their NIMA Kinase Partners Regulate Extracellular Matrix Remodeling and Intracellular Trafficking in Caenorhabditis elegans. Genetics (2016) 0.75
X-linked intellectual disability gene CASK regulates postnatal brain growth in a non-cell autonomous manner. Acta Neuropathol Commun (2016) 0.75
A histone H4 lysine 20 methyltransferase couples environmental cues to sensory neuron control of developmental plasticity. Development (2017) 0.75
Should I stay or should I go? Identification of novel nutritionally regulated developmental checkpoints in C. elegans. Worm (2014) 0.75
C30F12.4 influences oogenesis, fat metabolism, and lifespan in C. elegans. Protein Cell (2016) 0.75
Phenotypic plasticity and remodeling in the stress-induced Caenorhabditis elegans dauer. Wiley Interdiscip Rev Dev Biol (2017) 0.75
Small-molecule pheromones and hormones controlling nematode development. Nat Chem Biol (2017) 0.75
Gene expression profiling to investigate tyrosol-induced lifespan extension in Caenorhabditis elegans. Eur J Nutr (2015) 0.75
Early developmental stages of Ascaris lumbricoides featured by high-resolution mass spectrometry. Parasitol Res (2016) 0.75
Mutations in the Caenorhabditis elegans orthologs of human genes required for mitochondrial tRNA modification cause similar electron transport chain defects but different nuclear responses. PLoS Genet (2017) 0.75
Lipid and Carbohydrate Metabolism in Caenorhabditis elegans. Genetics (2017) 0.75
Molting in C. elegans. Worm (2017) 0.75
The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development (2004) 5.27
Analysis of long-lived C. elegans daf-2 mutants using serial analysis of gene expression. Genome Res (2005) 1.93
Maize centromere structure and evolution: sequence analysis of centromeres 2 and 5 reveals dynamic Loci shaped primarily by retrotransposons. PLoS Genet (2009) 1.71
Aluminum tolerance in maize is associated with higher MATE1 gene copy number. Proc Natl Acad Sci U S A (2013) 1.63
Quantitative proteomics identifies ferritin in the innate immune response of C. elegans. Virulence (2011) 1.53
Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Mol Cell (2004) 1.40
Positive selection of Caenorhabditis elegans mutants with increased stress resistance and longevity. Genetics (2003) 1.37
Insulin receptor substrate and p55 orthologous adaptor proteins function in the Caenorhabditis elegans daf-2/insulin-like signaling pathway. J Biol Chem (2002) 1.32
SAGE surveys C. elegans carbohydrate metabolism: evidence for an anaerobic shift in the long-lived dauer larva. Mech Ageing Dev (2003) 1.26
Genetic balancers. WormBook (2006) 1.19
Interaction of structure-specific and promiscuous G-protein-coupled receptors mediates small-molecule signaling in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2012) 1.05
Pheromone sensing regulates Caenorhabditis elegans lifespan and stress resistance via the deacetylase SIR-2.1. Proc Natl Acad Sci U S A (2013) 1.04
Antagonistic Smad transcription factors control the dauer/non-dauer switch in C. elegans. Development (2010) 1.00
Targets of DAF-16 involved in Caenorhabditis elegans adult longevity and dauer formation. Exp Gerontol (2006) 0.91
Intragenomic conflict between the two major knob repeats of maize. Genetics (2013) 0.90
Genes that may modulate longevity in C. elegans in both dauer larvae and long-lived daf-2 adults. Exp Gerontol (2007) 0.90
Deep SAGE analysis of the Caenorhabditis elegans transcriptome. Nucleic Acids Res (2010) 0.88
RNAi screen of DAF-16/FOXO target genes in C. elegans links pathogenesis and dauer formation. PLoS One (2010) 0.87
Increased longevity of some C. elegans mitochondrial mutants explained by activation of an alternative energy-producing pathway. Mech Ageing Dev (2011) 0.87
Chromosome painting for plant biotechnology. Methods Mol Biol (2011) 0.86
Effects of a Caenorhabditis elegans dauer pheromone ascaroside on physiology and signal transduction pathways. J Chem Ecol (2009) 0.86
MISC-1/OGC links mitochondrial metabolism, apoptosis and insulin secretion. PLoS One (2011) 0.83
Discovery of novel alternatively spliced C. elegans transcripts by computational analysis of SAGE data. BMC Genomics (2007) 0.83
Caenorhabditis elegans SDF-9 enhances insulin/insulin-like signaling through interaction with DAF-2. Genetics (2007) 0.83
Localization of a guanylyl cyclase to chemosensory cilia requires the novel ciliary MYND domain protein DAF-25. PLoS Genet (2010) 0.81
Repression of a potassium channel by nuclear hormone receptor and TGF-β signaling modulates insulin signaling in Caenorhabditis elegans. PLoS Genet (2012) 0.79
Regulation of metabolism in Caenorhabditis elegans longevity. J Biol (2010) 0.78
Function of the PHA-4/FOXA transcription factor during C. elegans post-embryonic development. BMC Dev Biol (2008) 0.78
Alternative polyadenylation results in a truncated daf-4 BMP receptor that antagonizes DAF-7-mediated development in Caenorhabditis elegans. J Biol Chem (2004) 0.78
Amino Acid Substitutions in the Caenorhabditis elegans RNA Polymerase II Large Subunit AMA-1/RPB-1 that Result in α-Amanitin Resistance and/or Reduced Function. G3 (Bethesda) (2011) 0.76
Labeling meiotic chromosomes in maize with fluorescence in situ hybridization. Methods Mol Biol (2013) 0.75