Detecting genotype x age interaction.

Multivariate variance-components analysis of longitudinal blood pressure measurements from the Framingham Heart Study. BMC Genet (2003) 1.34

Genetic basis of neurocognitive decline and reduced white-matter integrity in normal human brain aging. Proc Natl Acad Sci U S A (2013) 1.11

Strategy and model building in the fourth dimension: a null model for genotype x age interaction as a Gaussian stationary stochastic process. BMC Genet (2003) 1.08

Genetic and environmental influences on infant weight and weight change: the Fels Longitudinal Study. Am J Hum Biol (2007) 1.05

A genomewide linkage scan for quantitative trait loci influencing the craniofacial complex in baboons (Papio hamadryas spp.). Genetics (2008) 0.92

Genotype×age interaction in human transcriptional ageing. Mech Ageing Dev (2012) 0.88

Pleiotropic effects on cardiovascular risk factors within and between the fourth and sixth decades of life: implications for genotype x age interactions. BMC Genet (2003) 0.83

A comparison of discrete versus continuous environment in a variance components-based linkage analysis of the COGA data. BMC Genet (2005) 0.78

Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet (1998) 40.97

Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks. Nat Med (2001) 16.65

Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns. Cancer Res (2001) 8.34

Large upward bias in estimation of locus-specific effects from genomewide scans. Am J Hum Genet (2001) 7.53

Choice behavior and the accessibility of the reinforcer. J Exp Anal Behav (1972) 6.14

Bivariate quantitative trait linkage analysis: pleiotropy versus co-incident linkages. Genet Epidemiol (1997) 6.08

Testing the robustness of the likelihood-ratio test in a variance-component quantitative-trait loci-mapping procedure. Am J Hum Genet (1999) 4.54

The effects of frequent nocturnal home hemodialysis: the Frequent Hemodialysis Network Nocturnal Trial. Kidney Int (2011) 4.27

Genetic and environmental contributions to cardiovascular risk factors in Mexican Americans. The San Antonio Family Heart Study. Circulation (1996) 4.10

Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome. Proc Natl Acad Sci U S A (2000) 3.44

A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2. Nat Genet (1997) 3.37

A variance component approach to dichotomous trait linkage analysis using a threshold model. Genet Epidemiol (1997) 3.33

An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians. Am J Hum Genet (1998) 3.16

GAW12: simulated genome scan, sequence, and family data for a common disease. Genet Epidemiol (2001) 3.13

Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. I. Likelihood formulation and simulation results. Am J Hum Genet (1999) 2.88

Expression cloning of a human DNA repair gene involved in xeroderma pigmentosum group C. Nature (1992) 2.88

Body mass index during childhood, adolescence and young adulthood in relation to adult overweight and adiposity: the Fels Longitudinal Study. Int J Obes Relat Metab Disord (2000) 2.84

GAW10: simulated family data for a common oligogenic disease with quantitative risk factors. Genet Epidemiol (1997) 2.68

Prohead and DNA-gp3-dependent ATPase activity of the DNA packaging protein gp16 of bacteriophage phi 29. J Mol Biol (1987) 2.59

Genetic control over the resting brain. Proc Natl Acad Sci U S A (2010) 2.45

Preventive care: do we practice what we preach? Am J Public Health (1987) 2.44

Statistical properties of a variance components method for quantitative trait linkage analysis in nuclear families and extended pedigrees. Genet Epidemiol (1997) 2.43

Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans. Am J Hum Genet (1999) 2.42

Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees. Science (2000) 2.35

Evidence for linkage of regions on chromosomes 6 and 11 to plasma glucose concentrations in Mexican Americans. Genome Res (1996) 2.24

Causal explanations as a risk factor for depression: theory and evidence. Psychol Rev (1984) 2.24

Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. II. Alcoholism and event-related potentials. Am J Hum Genet (1999) 2.23

Effects of genotype-by-sex interaction on quantitative trait linkage analysis. Genet Epidemiol (1997) 2.11

Power of variance component linkage analysis to detect quantitative trait loci. Ann Hum Genet (1999) 2.10

Interrater reliability of roentgenological evaluation of the lumbar spine in lateral bending. J Manipulative Physiol Ther (1990) 2.04

Hemoglobin concentration of high-altitude Tibetans and Bolivian Aymara. Am J Phys Anthropol (1998) 1.99

Fractional anisotropy of water diffusion in cerebral white matter across the lifespan. Neurobiol Aging (2010) 1.95

A major locus for fasting insulin concentrations and insulin resistance on chromosome 6q with strong pleiotropic effects on obesity-related phenotypes in nondiabetic Mexican Americans. Am J Hum Genet (2001) 1.91

Genes necessary for expression of a virulence determinant and for transmission of Plasmodium falciparum are located on a 0.3-megabase region of chromosome 9. Proc Natl Acad Sci U S A (1993) 1.88

The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome. J Clin Endocrinol Metab (2001) 1.82

Endophenotypes as quantitative risk factors for psychiatric disease: rationale and study design. Am J Med Genet (2001) 1.78

Monoclonal antibodies distinguish between storage and secreted forms of eosinophil cationic protein. Nature (1984) 1.75

Genetics of microstructure of cerebral white matter using diffusion tensor imaging. Neuroimage (2010) 1.70

Genetic susceptibility to thrombosis and its relationship to physiological risk factors: the GAIT study. Genetic Analysis of Idiopathic Thrombophilia. Am J Hum Genet (2000) 1.69

Total-body and regional bone mineral content and areal bone mineral density in children aged 8-18 y: the Fels Longitudinal Study. Am J Clin Nutr (1998) 1.69

Genetic determinants of hemostasis phenotypes in Spanish families. Circulation (2000) 1.63

Klippel-Trenaunay syndrome. Am J Med Genet (1998) 1.62

Genetics of atherosclerosis risk factors in Mexican Americans. Nutr Rev (1999) 1.61

Major gene for percent of oxygen saturation of arterial hemoglobin in Tibetan highlanders. Am J Phys Anthropol (1994) 1.59

Biogenesis of mitochondria in germinating peanut cotyledons. Plant Physiol (1966) 1.56

Exploring positional candidate genes: linkage conditional on measured genotype. Behav Genet (2004) 1.56

Hypocholesterolaemia in malignancy due to elevated low-density-lipoprotein-receptor activity in tumour cells: evidence from studies in patients with leukaemia. Lancet (1985) 1.46

Statistical genetic approaches to human adaptability. 1993. Hum Biol (2009) 1.46

Comparison of epinephrine with vasopressin on bone marrow blood flow in an animal model of hypovolemic shock and subsequent cardiac arrest. Crit Care Med (2001) 1.46

Genetic contribution of the endothelial constitutive nitric oxide synthase gene to plasma nitric oxide levels. Arterioscler Thromb Vasc Biol (1997) 1.44

Genetic analysis of susceptibility to infection with Ascaris lumbricoides. Am J Trop Med Hyg (1999) 1.44

Quantitative trait loci analysis of human event-related brain potentials: P3 voltage. Electroencephalogr Clin Neurophysiol (1998) 1.43

The landing of the NEAR-Shoemaker spacecraft on asteroid 433 Eros. Nature (2001) 1.41

Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells. Oncogene (2000) 1.41

Outcome from injury: general health, work status, and satisfaction 12 months after trauma. J Trauma (2000) 1.40

Eosinophil granule proteins in cardiopulmonary bypass with and without heparin coating. Ann Thorac Surg (1995) 1.40

Designing clinical trials on energy healing: ancient art encounters medical science. Altern Ther Health Med (2001) 1.39

Simulation of a common oligogenic disease with quantitative risk factors. GAW9 problem 2: the answers. Genet Epidemiol (1995) 1.39

Lumbar motion trends and correlation with low back pain. Part I. A roentgenological evaluation of coupled lumbar motion in lateral bending. J Manipulative Physiol Ther (1992) 1.37

Measurement of two- and three-nucleon short-range correlation probabilities in nuclei. Phys Rev Lett (2006) 1.37

Impact of CYP2C8*3 on paclitaxel clearance: a population pharmacokinetic and pharmacogenomic study in 93 patients with ovarian cancer. Pharmacogenomics J (2010) 1.33

Quantitative genetic analysis of arterial oxygen saturation in Tibetan highlanders. Hum Biol (1997) 1.33

Genetic analysis of the IRS. Pleiotropic effects of genes influencing insulin levels on lipoprotein and obesity measures. Arterioscler Thromb Vasc Biol (1996) 1.30

Fractional anisotropy of cerebral white matter and thickness of cortical gray matter across the lifespan. Neuroimage (2011) 1.30

Attributional style and depressive symptoms among children. J Abnorm Psychol (1984) 1.29

Genetics of primary cerebral gyrification: Heritability of length, depth and area of primary sulci in an extended pedigree of Papio baboons. Neuroimage (2009) 1.29

Eosinophil cationic protein (ECP): molecular and biological properties and the use of ECP as a marker of eosinophil activation in disease. Clin Exp Allergy (1999) 1.28

Smoking behavior is under the influence of a major quantitative trait locus on human chromosome 5q. Genet Epidemiol (1999) 1.28

Nausea in cancer chemotherapy is inversely related to urinary cortisol excretion. Br J Cancer (1992) 1.28

Gamete-competition models. Am J Hum Genet (2000) 1.28

Determinants of variation in human serum paraoxonase activity. Heredity (Edinb) (2008) 1.27

Functional effects of the ABO locus polymorphism on plasma levels of von Willebrand factor, factor VIII, and activated partial thromboplastin time. Arterioscler Thromb Vasc Biol (2000) 1.27

Detection of differential gene flow from patterns of quantitative variation. Hum Biol (1990) 1.25

Exposure to Schistosoma mansoni infection in a rural area in Brazil. II: household risk factors. Trop Med Int Health (2001) 1.24

Plasma HDL cholesterol, triglycerides, and adiposity. A quantitative genetic test of the conjoint trait hypothesis in the San Antonio Family Heart Study. Circulation (1995) 1.23

An empirical test of the significance of an observed quantitative trait locus effect that preserves additive genetic variation. Genet Epidemiol (1999) 1.23

Initiation events in in-vitro packaging of bacteriophage phi 29 DNA-gp3. J Mol Biol (1987) 1.23

Amplitude of visual P3 event-related potential as a phenotypic marker for a predisposition to alcoholism: preliminary results from the COGA Project. Collaborative Study on the Genetics of Alcoholism. Alcohol Clin Exp Res (1998) 1.22

Calcium and the aging nervous system. Neurobiol Aging (1987) 1.22

Quantitative variation in obesity-related traits and insulin precursors linked to the OB gene region on human chromosome 7. Am J Hum Genet (1996) 1.22

A major susceptibility locus influencing plasma triglyceride concentrations is located on chromosome 15q in Mexican Americans. Am J Hum Genet (2000) 1.22

Monitoring global change: Comparison of forest cover estimates using remote sensing and inventory approaches. Environ Monit Assess (1993) 1.19

Genetic epidemiological approaches to the search for osteoporosis genes. J Bone Miner Res (2000) 1.19

Evidence for nonrandom hydrophobicity structures in protein chains. Proc Natl Acad Sci U S A (1996) 1.19

Clustering ECG complexes using hermite functions and self-organizing maps. IEEE Trans Biomed Eng (2000) 1.19

Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death. Proc Natl Acad Sci U S A (2000) 1.19

Power of variance component linkage analysis to detect epistasis. Genet Epidemiol (1997) 1.18

Biochemical pharmacology and resistance to 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine, a novel analogue of cladribine in human leukemic cells. Clin Cancer Res (1999) 1.18

Indirect evidence of bronchial inflammation assessed by titration of inflammatory mediators in BAL fluid of patients with asthma. J Allergy Clin Immunol (1991) 1.17

A quantitative trait locus influencing BMI maps to the region of the beta-3 adrenergic receptor. Diabetes (1999) 1.16

Zinc and the common cold: a meta-analysis revisited. J Nutr (2000) 1.16

The first seriatim study into old age for weight, stature and BMI: the Fels Longitudinal Study. J Nutr Health Aging (2009) 1.15

Antibody to poliovirus genome-linked protein (VPg) precipitates in vitro synthesized RNA attached to VPg-precursor polypeptide(s). Virus Res (1984) 1.15

Lipids, lipoproteins, lifestyle, adiposity and fat-free mass during middle age: the Fels Longitudinal Study. Int J Obes (Lond) (2006) 1.15

Low-density lipoprotein as a carrier of antitumoral drugs: in vivo fate of drug-human low-density lipoprotein complexes in mice. Cancer Res (1986) 1.15

Ventilation and hypoxic ventilatory response of Tibetan and Aymara high altitude natives. Am J Phys Anthropol (1997) 1.15

Uptake of low density lipoproteins by human leukemic cells in vivo: relation to plasma lipoprotein levels and possible relevance for selective chemotherapy. Proc Natl Acad Sci U S A (1990) 1.15

The effect of pedigree complexity on quantitative trait linkage analysis. Genet Epidemiol (2001) 1.14

Quantitative trait locus detection using combined linkage/disequilibrium analysis. Genet Epidemiol (1999) 1.14