Published in Am J Hum Genet on October 09, 2001
Genetics of Atherosclerosis in Mexican Americans | NCT00005462
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet (2009) 15.15
Common regulatory variation impacts gene expression in a cell type-dependent manner. Science (2009) 11.28
Estimating polygenic effects using markers of the entire genome. Genetics (2003) 8.67
Genome-wide association studies: potential next steps on a genetic journey. Hum Mol Genet (2008) 7.54
Neuregulin 1 and susceptibility to schizophrenia. Am J Hum Genet (2002) 7.40
Overcoming the winner's curse: estimating penetrance parameters from case-control data. Am J Hum Genet (2007) 6.99
Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. Am J Hum Genet (2003) 6.63
Accuracy of predicting the genetic risk of disease using a genome-wide approach. PLoS One (2008) 4.96
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci U S A (2010) 4.30
Genomewide linkage analysis of body mass index across 28 years of the Framingham Heart Study. Am J Hum Genet (2002) 4.07
A genome-wide scan for common alleles affecting risk for autism. Hum Mol Genet (2010) 3.42
Gene expression in skin and lymphoblastoid cells: Refined statistical method reveals extensive overlap in cis-eQTL signals. Am J Hum Genet (2010) 3.28
Mapping genetic loci that determine leukocyte telomere length in a large sample of unselected female sibling pairs. Am J Hum Genet (2006) 3.25
Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration. Am J Hum Genet (2005) 3.19
Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2. Nat Genet (2011) 3.02
Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue. PLoS Genet (2011) 2.68
Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk. BMC Med Genet (2008) 2.63
What can genome-wide association studies tell us about the genetics of common disease? PLoS Genet (2008) 2.35
Multiple genes for essential-hypertension susceptibility on chromosome 1q. Am J Hum Genet (2006) 2.34
Mendelian randomization analysis with multiple genetic variants using summarized data. Genet Epidemiol (2013) 2.34
Cryptic multiple hypotheses testing in linear models: overestimated effect sizes and the winner's curse. Behav Ecol Sociobiol (2010) 2.34
Bias in estimates of quantitative-trait-locus effect in genome scans: demonstration of the phenomenon and a method-of-moments procedure for reducing bias. Am J Hum Genet (2002) 2.25
Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study. PLoS Genet (2011) 2.13
Estimating odds ratios in genome scans: an approximate conditional likelihood approach. Am J Hum Genet (2008) 2.12
Mapping determinants of variation in energy metabolism, respiration and flight in Drosophila. Genetics (2003) 2.07
Genome scan meta-analysis of schizophrenia and bipolar disorder, part I: Methods and power analysis. Am J Hum Genet (2003) 2.06
Genome-wide association studies: contribution of genomics to understanding blood pressure and essential hypertension. Curr Hypertens Rep (2010) 2.03
Quantitative trait locus mapping based on resampling in a vast maize testcross experiment and its relevance to quantitative genetics for complex traits. Genetics (2004) 2.02
Quantifying and correcting for the winner's curse in genetic association studies. Genet Epidemiol (2009) 2.02
Theoretical models of selection and mutation on quantitative traits. Philos Trans R Soc Lond B Biol Sci (2005) 2.00
Flexible design for following up positive findings. Am J Hum Genet (2007) 1.94
A genomewide linkage scan for quantitative-trait loci for obesity phenotypes. Am J Hum Genet (2002) 1.91
Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes. Nat Genet (2013) 1.91
A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection. PLoS Genet (2011) 1.83
Genomewide linkage study in 1,176 affected sister pair families identifies a significant susceptibility locus for endometriosis on chromosome 10q26. Am J Hum Genet (2005) 1.76
The complex genetics of multiple sclerosis: pitfalls and prospects. Brain (2008) 1.68
Polymorphisms at the G72/G30 gene locus, on 13q33, are associated with bipolar disorder in two independent pedigree series. Am J Hum Genet (2003) 1.66
Linkage of osteoporosis to chromosome 20p12 and association to BMP2. PLoS Biol (2003) 1.64
Upward bias in estimation of genetic effects. Am J Hum Genet (2002) 1.64
Nucleotide polymorphism and phenotypic associations within and around the phytochrome B2 Locus in European aspen (Populus tremula, Salicaceae). Genetics (2008) 1.61
Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals. Diabetologia (2011) 1.59
Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry. PLoS Genet (2013) 1.51
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus. Nat Genet (2013) 1.49
A genomewide linkage screen for relative hand skill in sibling pairs. Am J Hum Genet (2002) 1.46
Genome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritis. Am J Hum Genet (2008) 1.45
Genome-wide association studies: progress and potential for drug discovery and development. Nat Rev Drug Discov (2008) 1.45
Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics. Mol Psychiatry (2009) 1.44
Systemic lupus erythematosus susceptibility loci defined by genome scan meta-analysis. Hum Genet (2005) 1.44
A large-sample QTL study in mice: I. Growth. Mamm Genome (2004) 1.43
Power estimation and sample size determination for replication studies of genome-wide association studies. BMC Genomics (2016) 1.41
Tilting at quixotic trait loci (QTL): an evolutionary perspective on genetic causation. Genetics (2008) 1.33
Evidence for linkage of stature to chromosome 3p26 in a large U.K. Family data set ascertained for type 2 diabetes. Am J Hum Genet (2001) 1.32
Genome-wide mapping of susceptibility to coronary artery disease identifies a novel replicated locus on chromosome 17. PLoS Genet (2006) 1.29
BR-squared: a practical solution to the winner's curse in genome-wide scans. Hum Genet (2011) 1.28
Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies. PLoS One (2009) 1.28
Determinants of variation in human serum paraoxonase activity. Heredity (Edinb) (2008) 1.27
Genome-wide linkage analyses of quantitative and categorical autism subphenotypes. Biol Psychiatry (2008) 1.26
A systematic genomewide linkage study in 353 sib pairs with schizophrenia. Am J Hum Genet (2003) 1.24
Current status on Alzheimer disease molecular genetics: from past, to present, to future. Hum Mol Genet (2010) 1.20
Genome-wide scans for loci under selection in humans. Hum Genomics (2005) 1.19
Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia. Neuropsychopharmacology (2010) 1.19
Identification of quantitative trait loci that regulate Arabidopsis root system size and plasticity. Genetics (2005) 1.19
Is replication the gold standard for validating genome-wide association findings? PLoS One (2008) 1.18
A major susceptibility locus on chromosome 22q12 plays a critical role in the control of kala-azar. Am J Hum Genet (2003) 1.14
Genetic analysis of genome-scale recombination rate evolution in house mice. PLoS Genet (2011) 1.12
Overview of techniques to account for confounding due to population stratification and cryptic relatedness in genomic data association analyses. Heredity (Edinb) (2010) 1.11
TNFAIP3 gene polymorphisms are associated with response to TNF blockade in psoriasis. J Invest Dermatol (2011) 1.10
Proximal hip geometry is linked to several chromosomal regions: genome-wide linkage results from the Framingham Osteoporosis Study. Bone (2006) 1.10
Genome-wide association study of periodontal pathogen colonization. J Dent Res (2012) 1.10
ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample. Am J Med Genet B Neuropsychiatr Genet (2013) 1.08
Mendelian randomization in health research: using appropriate genetic variants and avoiding biased estimates. Econ Hum Biol (2013) 1.08
Quantitative founder-effect analysis of French Canadian families identifies specific loci contributing to metabolic phenotypes of hypertension. Am J Hum Genet (2005) 1.07
Linkage analysis of extremely discordant and concordant sibling pairs identifies quantitative trait loci influencing variation in human menopausal age. Am J Hum Genet (2004) 1.04
Integrated phenotypes: understanding trait covariation in plants and animals. Philos Trans R Soc Lond B Biol Sci (2014) 1.04
Association mapping of quantitative disease resistance in a natural population of loblolly pine (Pinus taeda L.). Genetics (2010) 1.00
Re-ranking sequencing variants in the post-GWAS era for accurate causal variant identification. PLoS Genet (2013) 1.00
Sex and age specific effects of chromosomal regions linked to body mass index in the Framingham Study. BMC Genet (2006) 1.00
Genome-wide analysis of epistasis in body mass index using multiple human populations. Eur J Hum Genet (2012) 1.00
Towards compendia of negative genetic association studies: an example for Alzheimer disease. Hum Genet (2005) 1.00
Unbiased estimation of odds ratios: combining genomewide association scans with replication studies. Genet Epidemiol (2009) 0.98
Linkage analysis of anorexia and bulimia nervosa cohorts using selected behavioral phenotypes as quantitative traits or covariates. Am J Med Genet B Neuropsychiatr Genet (2005) 0.98
Genome-wide association studies of chronic kidney disease: what have we learned? Nat Rev Nephrol (2011) 0.98
Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies. Am J Clin Nutr (2016) 0.98
Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts. Circ Cardiovasc Genet (2012) 0.97
Imprints of natural selection along environmental gradients in phenology-related genes of Quercus petraea. Genetics (2013) 0.96
CALHM1 polymorphism is not associated with late-onset Alzheimer disease. Ann Hum Genet (2009) 0.96
Quantifying and correcting for the winner's curse in quantitative-trait association studies. Genet Epidemiol (2011) 0.96
Evaluating the evidence for transmission distortion in human pedigrees. Genetics (2012) 0.96
Multiple quantitative trait loci mapping with cofactors and application of alternative variants of the false discovery rate in an enlarged granddaughter design. Genetics (2004) 0.95
Genome-wide linkage analysis of multiple measures of neuroticism of 2 large cohorts from Australia and the Netherlands. Arch Gen Psychiatry (2008) 0.94
Gene association studies in acute lung injury: replication and future direction. Am J Physiol Lung Cell Mol Physiol (2009) 0.93
A genomewide linkage scan for quantitative trait loci influencing the craniofacial complex in baboons (Papio hamadryas spp.). Genetics (2008) 0.92
Bivariate linkage study of proximal hip geometry and body size indices: the Framingham study. Calcif Tissue Int (2007) 0.92
Linkage and association of phospholipid transfer protein activity to LASS4. J Lipid Res (2011) 0.91
A genome-wide supported variant in CACNA1C influences hippocampal activation during episodic memory encoding and retrieval. Eur Arch Psychiatry Clin Neurosci (2013) 0.91
Confirmation of chromosome 7q11 locus for predisposition to intracranial aneurysm. Hum Genet (2003) 0.90
A genome-wide association study of osteochondritis dissecans in the Thoroughbred. Mamm Genome (2011) 0.89
Robust estimation of experimentwise P values applied to a genome scan of multiple asthma traits identifies a new region of significant linkage on chromosome 20q13. Am J Hum Genet (2005) 0.89
Bivariate genome-wide linkage analysis of femoral bone traits and leg lean mass: Framingham study. J Bone Miner Res (2009) 0.89
The future of genetic studies of complex human diseases. Science (1996) 64.76
Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet (1995) 49.77
Sequential tests for the detection of linkage. Am J Hum Genet (1955) 43.74
Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet (1998) 40.97
Efficiency of marker-assisted selection in the improvement of quantitative traits. Genetics (1990) 12.25
Robust variance-components approach for assessing genetic linkage in pedigrees. Am J Hum Genet (1994) 10.58
Mapping quantitative trait loci controlling milk production in dairy cattle by exploiting progeny testing. Genetics (1995) 9.26
Multipoint analysis of human quantitative genetic variation. Am J Hum Genet (1990) 9.09
Extensions to multivariate normal models for pedigree analysis. Ann Hum Genet (1982) 7.07
Extensions to pedigree analysis. III. Variance components by the scoring method. Ann Hum Genet (1976) 5.86
Simultaneous inference in epidemiological studies. Int J Epidemiol (1982) 5.77
The problem of multiple inference in studies designed to generate hypotheses. Am J Epidemiol (1985) 4.76
Testing the robustness of the likelihood-ratio test in a variance-component quantitative-trait loci-mapping procedure. Am J Hum Genet (1999) 4.54
How many diseases does it take to map a gene with SNPs? Nat Genet (2000) 4.16
True and false positive peaks in genomewide scans: applications of length-biased sampling to linkage mapping. Am J Hum Genet (1997) 3.28
Quantitative trait locus (QTL) mapping using different testers and independent population samples in maize reveals low power of QTL detection and large bias in estimates of QTL effects. Genetics (1998) 3.20
QTL analysis in plants; where are we now? Heredity (Edinb) (1998) 3.16
Linkage analysis in the presence of errors IV: joint pseudomarker analysis of linkage and/or linkage disequilibrium on a mixture of pedigrees and singletons when the mode of inheritance cannot be accurately specified. Am J Hum Genet (2000) 2.85
Variance component methods for detecting complex trait loci. Adv Genet (2001) 2.78
Gene mapping in the 20th and 21st centuries: statistical methods, data analysis, and experimental design. Hum Biol (2000) 2.65
Statistical properties of a variance components method for quantitative trait linkage analysis in nuclear families and extended pedigrees. Genet Epidemiol (1997) 2.43
Power of variance component linkage analysis to detect quantitative trait loci. Ann Hum Genet (1999) 2.10
Linkage analysis in the presence of errors I: complex-valued recombination fractions and complex phenotypes. Am J Hum Genet (2000) 2.05
Linkage analysis in the presence of errors II: marker-locus genotyping errors modeled with hypercomplex recombination fractions. Am J Hum Genet (2000) 1.98
Ascertainment and goodness of fit of variance component models for pedigree data. Prog Clin Biol Res (1984) 1.89
Multifactorial analysis of family data ascertained through truncation: a comparative evaluation of two methods of statistical inference. Am J Hum Genet (1988) 1.47
Robust inference for variance components models in families ascertained through probands: I. Conditioning on proband's phenotype. Genet Epidemiol (1987) 1.44
Quantitative trait locus mapping using human pedigrees. Hum Biol (2000) 1.40
The effects of conditioning on probands to correct for multiple ascertainment. Am J Hum Genet (1984) 1.40
The interpretation of lods in linkage analysis. Cytogenet Cell Genet (1976) 1.26
Correcting for ascertainment bias in the COGA data set. Genet Epidemiol (1999) 1.20
Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet (1998) 40.97
Bivariate quantitative trait linkage analysis: pleiotropy versus co-incident linkages. Genet Epidemiol (1997) 6.08
Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome. Nature (1989) 4.69
Testing the robustness of the likelihood-ratio test in a variance-component quantitative-trait loci-mapping procedure. Am J Hum Genet (1999) 4.54
How many diseases does it take to map a gene with SNPs? Nat Genet (2000) 4.16
Genetic and environmental contributions to cardiovascular risk factors in Mexican Americans. The San Antonio Family Heart Study. Circulation (1996) 4.10
Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12. Nat Genet (1996) 4.09
Two-trait-locus linkage analysis: a powerful strategy for mapping complex genetic traits. Am J Hum Genet (1993) 3.76
Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome. Proc Natl Acad Sci U S A (2000) 3.44
A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2. Nat Genet (1997) 3.37
A variance component approach to dichotomous trait linkage analysis using a threshold model. Genet Epidemiol (1997) 3.33
An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians. Am J Hum Genet (1998) 3.16
Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth. Dev Biol (2001) 3.13
GAW12: simulated genome scan, sequence, and family data for a common disease. Genet Epidemiol (2001) 3.13
Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. I. Likelihood formulation and simulation results. Am J Hum Genet (1999) 2.88
Linkage analysis in the presence of errors IV: joint pseudomarker analysis of linkage and/or linkage disequilibrium on a mixture of pedigrees and singletons when the mode of inheritance cannot be accurately specified. Am J Hum Genet (2000) 2.85
GAW10: simulated family data for a common oligogenic disease with quantitative risk factors. Genet Epidemiol (1997) 2.68
Genetic control over the resting brain. Proc Natl Acad Sci U S A (2010) 2.45
Statistical properties of a variance components method for quantitative trait linkage analysis in nuclear families and extended pedigrees. Genet Epidemiol (1997) 2.43
Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans. Am J Hum Genet (1999) 2.42
Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees. Science (2000) 2.35
Linkage analysis in the presence of errors III: marker loci and their map as nuisance parameters. Am J Hum Genet (2000) 2.35
Evidence for linkage of regions on chromosomes 6 and 11 to plasma glucose concentrations in Mexican Americans. Genome Res (1996) 2.24
Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. II. Alcoholism and event-related potentials. Am J Hum Genet (1999) 2.23
A genomewide screen for schizophrenia genes in an isolated Finnish subpopulation, suggesting multiple susceptibility loci. Am J Hum Genet (1999) 2.15
Effects of genotype-by-sex interaction on quantitative trait linkage analysis. Genet Epidemiol (1997) 2.11
Power of variance component linkage analysis to detect quantitative trait loci. Ann Hum Genet (1999) 2.10
Linkage analysis in the presence of errors I: complex-valued recombination fractions and complex phenotypes. Am J Hum Genet (2000) 2.05
Hemoglobin concentration of high-altitude Tibetans and Bolivian Aymara. Am J Phys Anthropol (1998) 1.99
Linkage analysis in the presence of errors II: marker-locus genotyping errors modeled with hypercomplex recombination fractions. Am J Hum Genet (2000) 1.98
Fractional anisotropy of water diffusion in cerebral white matter across the lifespan. Neurobiol Aging (2010) 1.95
Two loci on chromosomes 2 and X for premature coronary heart disease identified in early- and late-settlement populations of Finland. Am J Hum Genet (2000) 1.93
A major locus for fasting insulin concentrations and insulin resistance on chromosome 6q with strong pleiotropic effects on obesity-related phenotypes in nondiabetic Mexican Americans. Am J Hum Genet (2001) 1.91
The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome. J Clin Endocrinol Metab (2001) 1.82
A putative vulnerability locus to multiple sclerosis maps to 5p14-p12 in a region syntenic to the murine locus Eae2. Nat Genet (1996) 1.81
Endophenotypes as quantitative risk factors for psychiatric disease: rationale and study design. Am J Med Genet (2001) 1.78
Genome-wide scan for schizophrenia in the Finnish population: evidence for a locus on chromosome 7q22. Hum Mol Genet (2000) 1.77
Genetics of microstructure of cerebral white matter using diffusion tensor imaging. Neuroimage (2010) 1.70
Genetic susceptibility to thrombosis and its relationship to physiological risk factors: the GAIT study. Genetic Analysis of Idiopathic Thrombophilia. Am J Hum Genet (2000) 1.69
Genetic determinants of hemostasis phenotypes in Spanish families. Circulation (2000) 1.63
Genetics of atherosclerosis risk factors in Mexican Americans. Nutr Rev (1999) 1.61
Major gene for percent of oxygen saturation of arterial hemoglobin in Tibetan highlanders. Am J Phys Anthropol (1994) 1.59
Genomewide scan of multiple sclerosis in Finnish multiplex families. Am J Hum Genet (1997) 1.57
Genome-wide scan in a nationwide study sample of schizophrenia families in Finland reveals susceptibility loci on chromosomes 2q and 5q. Hum Mol Genet (2001) 1.57
Exploring positional candidate genes: linkage conditional on measured genotype. Behav Genet (2004) 1.56
Linkage of familial combined hyperlipidaemia to chromosome 1q21-q23. Nat Genet (1998) 1.52
Statistical genetic approaches to human adaptability. 1993. Hum Biol (2009) 1.46
Genetic analysis of susceptibility to infection with Ascaris lumbricoides. Am J Trop Med Hyg (1999) 1.44
Genetic contribution of the endothelial constitutive nitric oxide synthase gene to plasma nitric oxide levels. Arterioscler Thromb Vasc Biol (1997) 1.44
Quantitative trait loci analysis of human event-related brain potentials: P3 voltage. Electroencephalogr Clin Neurophysiol (1998) 1.43
Simulation of a common oligogenic disease with quantitative risk factors. GAW9 problem 2: the answers. Genet Epidemiol (1995) 1.39
New polymorphic microsatellite markers place the haemochromatosis gene telomeric to D6S105. Hum Mol Genet (1995) 1.38
A radiation hybrid map of 506 STS markers spanning human chromosome 11. Nat Genet (1994) 1.35
Genome scan for predisposing loci for distal interphalangeal joint osteoarthritis: evidence for a locus on 2q. Am J Hum Genet (1999) 1.35
Quantitative genetic analysis of arterial oxygen saturation in Tibetan highlanders. Hum Biol (1997) 1.33
Genetic analysis of the IRS. Pleiotropic effects of genes influencing insulin levels on lipoprotein and obesity measures. Arterioscler Thromb Vasc Biol (1996) 1.30
Fractional anisotropy of cerebral white matter and thickness of cortical gray matter across the lifespan. Neuroimage (2011) 1.30
A susceptibility locus for human systemic lupus erythematosus (hSLE1) on chromosome 2q. J Autoimmun (2000) 1.29
A genome scan in families from Australia and New Zealand confirms the presence of a maternal susceptibility locus for pre-eclampsia, on chromosome 2. Am J Hum Genet (2000) 1.29
Genetics of primary cerebral gyrification: Heritability of length, depth and area of primary sulci in an extended pedigree of Papio baboons. Neuroimage (2009) 1.29
Smoking behavior is under the influence of a major quantitative trait locus on human chromosome 5q. Genet Epidemiol (1999) 1.28
Detecting genotype x age interaction. Genet Epidemiol (2001) 1.28
Gamete-competition models. Am J Hum Genet (2000) 1.28
Determinants of variation in human serum paraoxonase activity. Heredity (Edinb) (2008) 1.27
Linkage disequilibrium in isolated populations: Finland and a young sub-population of Kuusamo. Eur J Hum Genet (2000) 1.27
Functional effects of the ABO locus polymorphism on plasma levels of von Willebrand factor, factor VIII, and activated partial thromboplastin time. Arterioscler Thromb Vasc Biol (2000) 1.27
Detection of differential gene flow from patterns of quantitative variation. Hum Biol (1990) 1.25
Exposure to Schistosoma mansoni infection in a rural area in Brazil. II: household risk factors. Trop Med Int Health (2001) 1.24
Plasma HDL cholesterol, triglycerides, and adiposity. A quantitative genetic test of the conjoint trait hypothesis in the San Antonio Family Heart Study. Circulation (1995) 1.23
An empirical test of the significance of an observed quantitative trait locus effect that preserves additive genetic variation. Genet Epidemiol (1999) 1.23
Amplitude of visual P3 event-related potential as a phenotypic marker for a predisposition to alcoholism: preliminary results from the COGA Project. Collaborative Study on the Genetics of Alcoholism. Alcohol Clin Exp Res (1998) 1.22
A major susceptibility locus influencing plasma triglyceride concentrations is located on chromosome 15q in Mexican Americans. Am J Hum Genet (2000) 1.22
Schizophrenia in the genetic isolate of Finland. Am J Med Genet (1997) 1.22
Quantitative variation in obesity-related traits and insulin precursors linked to the OB gene region on human chromosome 7. Am J Hum Genet (1996) 1.22
Genomewide scan for familial combined hyperlipidemia genes in finnish families, suggesting multiple susceptibility loci influencing triglyceride, cholesterol, and apolipoprotein B levels. Am J Hum Genet (1999) 1.21
Genetic epidemiological approaches to the search for osteoporosis genes. J Bone Miner Res (2000) 1.19
Genome-wide scan of predisposing loci for increased diastolic blood pressure in Finnish siblings. J Hypertens (2000) 1.19
Power of variance component linkage analysis to detect epistasis. Genet Epidemiol (1997) 1.18
A quantitative trait locus influencing BMI maps to the region of the beta-3 adrenergic receptor. Diabetes (1999) 1.16
Ventilation and hypoxic ventilatory response of Tibetan and Aymara high altitude natives. Am J Phys Anthropol (1997) 1.15
The effect of pedigree complexity on quantitative trait linkage analysis. Genet Epidemiol (2001) 1.14
Quantitative trait locus detection using combined linkage/disequilibrium analysis. Genet Epidemiol (1999) 1.14
The mitochondrial rhomboid protease PSARL is a new candidate gene for type 2 diabetes. Diabetologia (2005) 1.12
Comparison of variance components and sibpair-based approaches to quantitative trait linkage analysis in unselected samples. Genet Epidemiol (1999) 1.12
A genome search identifies major quantitative trait loci on human chromosomes 3 and 4 that influence cholesterol concentrations in small LDL particles. Arterioscler Thromb Vasc Biol (1999) 1.12
Linkage analysis demonstrates that the prothrombin G20210A mutation jointly influences plasma prothrombin levels and risk of thrombosis. Blood (2000) 1.11
Searching for genes underlying normal variation in human adiposity. J Mol Med (Berl) (2001) 1.11
Anxiety proneness linked to epistatic loci in genome scan of human personality traits. Am J Med Genet (1998) 1.11
Genetics of event-related brain potentials in response to a semantic priming paradigm in families with a history of alcoholism. Am J Hum Genet (2000) 1.11
Common genetic influences on depression, alcohol, and substance use disorders in Mexican-American families. Am J Med Genet B Neuropsychiatr Genet (2011) 1.10
Genetic basis of variation in carotid artery wall thickness. Stroke (1996) 1.08
Human pedigree-based quantitative-trait-locus mapping: localization of two genes influencing HDL-cholesterol metabolism. Am J Hum Genet (1999) 1.08
The quantitative trait locus on chromosome 2 for serum leptin levels is confirmed in African-Americans. Diabetes (1999) 1.08
Linkage analysis of putative schizophrenia gene candidate regions on chromosomes 3p, 5q, 6p, 8p, 20p and 22q in a population-based sampled Finnish family set. Mol Psychiatry (1998) 1.08
A comprehensive linkage analysis of chromosome 21q22 supports prior evidence for a putative bipolar affective disorder locus. Am J Hum Genet (1999) 1.07
Interactions between variants in the beta3-adrenergic receptor and peroxisome proliferator-activated receptor-gamma2 genes and obesity. Diabetes Care (2001) 1.06
Linkage disequilibrium analysis in the genetically isolated Norfolk Island population. Heredity (Edinb) (2007) 1.06
Pleiotropy and genotype by diet interaction in a baboon model for atherosclerosis: a multivariate quantitative genetic analysis of HDL subfractions in two dietary environments. Arterioscler Thromb Vasc Biol (1999) 1.05
Normal variation in leptin levels in associated with polymorphisms in the proopiomelanocortin gene, POMC. J Clin Endocrinol Metab (1999) 1.05