C Brayne

Author PubWeight™ 123.13‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet 2013 9.46
2 The prevalence of frontotemporal dementia. Neurology 2002 5.73
3 Rates and risk factors for dementia and Alzheimer's disease: results from EURODEM pooled analyses. EURODEM Incidence Research Group and Work Groups. European Studies of Dementia. Neurology 1999 3.95
4 The prevalence of dementia in Europe: a collaborative study of 1980-1990 findings. Eurodem Prevalence Research Group. Int J Epidemiol 1991 3.70
5 Gender differences in the incidence of AD and vascular dementia: The EURODEM Studies. EURODEM Incidence Research Group. Neurology 1999 2.13
6 Frequency and distribution of Alzheimer's disease in Europe: a collaborative study of 1980-1990 prevalence findings. The EURODEM-Prevalence Research Group. Ann Neurol 1991 1.89
7 Dementia and survival in Parkinson disease: a 12-year population study. Neurology 2008 1.86
8 Alpha-2 macroglobulin polymorphism and Alzheimer disease risk in the UK. Nat Genet 1999 1.79
9 Incidence of early-onset dementias in Cambridgeshire, United Kingdom. Neurology 2008 1.76
10 Incidence of dementia in a population older than 75 years in the United Kingdom. Arch Gen Psychiatry 1994 1.66
11 Mild cognitive impairment: a concept in evolution. J Intern Med 2014 1.65
12 Stroke, vascular risk factors and depression: Cross-sectional study in a UK Caribbean-born population. Br J Psychiatry 2001 1.62
13 The impact on prevalence of dementia in the oldest age groups of differential mortality patterns: a deterministic approach. Int J Epidemiol 1998 1.62
14 CAMCOG--a concise neuropsychological test to assist dementia diagnosis: socio-demographic determinants in an elderly population sample. Br J Clin Psychol 1995 1.62
15 Exploring the impact of prevalence and mortality on incidence of dementia in the oldest old: the sensitivity of a deterministic approach. Neuroepidemiology 2001 1.60
16 A systematic review of depression and mental illness preceding Parkinson's disease. Acta Neurol Scand 2006 1.49
17 Cognition and survival: an exploration in a large multicentre study of the population aged 65 years and over. Int J Epidemiol 2001 1.48
18 Increased fructose intake as a risk factor for dementia. J Gerontol A Biol Sci Med Sci 2010 1.48
19 Hippocampal tau pathology is related to neuroanatomical connections: an ageing population-based study. Brain 2009 1.43
20 Effect of smoking on global cognitive function in nondemented elderly. Neurology 2004 1.42
21 Profile of disability in elderly people: estimates from a longitudinal population study. BMJ 1999 1.38
22 Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain. Neurobiol Aging 2008 1.35
23 Population norms for the MMSE in the very old: estimates based on longitudinal data. Mini-Mental State Examination. Neurology 2000 1.35
24 Patterns and stages of alpha-synucleinopathy: Relevance in a population-based cohort. Neurology 2008 1.32
25 Smoking, drinking, and other life style factors and cognitive function in men in the Caerphilly cohort. J Epidemiol Community Health 1999 1.30
26 Staging of cytoskeletal and beta-amyloid changes in human isocortex reveals biphasic synaptic protein response during progression of Alzheimer's disease. Am J Pathol 2000 1.28
27 Factors associated with functional decline and improvement in a very elderly community-dwelling population. Am J Epidemiol 1999 1.22
28 Setting the minimal metrically detectable change on disability rating scales. Arch Phys Med Rehabil 1997 1.19
29 Neuropathological findings in the very old. Results from the first 101 brains of a population-based longitudinal study of dementing disorders. Ann N Y Acad Sci 2000 1.17
30 White matter lesions in an unselected cohort of the elderly: astrocytic, microglial and oligodendrocyte precursor cell responses. Neuropathol Appl Neurobiol 2007 1.14
31 Intentional weight loss in overweight and obese individuals and cognitive function: a systematic review and meta-analysis. Obes Rev 2011 1.12
32 Genome-wide association study of Alzheimer's disease with psychotic symptoms. Mol Psychiatry 2011 1.11
33 The ACE gene and Alzheimer's disease susceptibility. J Med Genet 2000 1.11
34 The epidemiology of Parkinson's disease in an Australian population. Neuroepidemiology 1998 1.08
35 Depression, APOE genotype and subjective memory impairment: a cross-sectional study in an African-Caribbean population. Psychol Med 2001 1.08
36 Aging and lymphocyte subpopulations: whole-blood analysis of immune markers in a large population sample of healthy elderly individuals. Exp Gerontol 1998 1.07
37 Cognitive function in the Caerphilly study: associations with age social class, education and mood. Eur J Epidemiol 1999 1.05
38 Incidence of functional decline and improvement in a community-dwelling, very elderly population. Am J Epidemiol 1997 1.05
39 Association analysis of 528 intra-genic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease. Am J Med Genet B Neuropsychiatr Genet 2008 1.04
40 Cognitive impairment in elderly people: population based estimate of the future in England, Scotland, and Wales. BMJ 1997 1.04
41 Decline across different domains of cognitive function in normal ageing: results of a longitudinal population-based study using CAMCOG. Int J Geriatr Psychiatry 2000 1.03
42 Prospective association between emotional health and clinical evidence of Parkinson's disease. Eur J Neurol 2008 1.03
43 The neuropathological profile of mild cognitive impairment (MCI): a systematic review. Mol Psychiatry 2011 1.02
44 Influence of apolipoprotein E genotype on the risk of cognitive deterioration in moderate drinkers and smokers. Epidemiology 2000 1.01
45 Socioeconomic status and the expectation of disability in old age: estimates for England. J Epidemiol Community Health 2000 1.01
46 Apolipoprotein E4 is only a weak predictor of dementia and cognitive decline in the general population. J Med Genet 2002 1.00
47 Microglial activation in white matter lesions and nonlesional white matter of ageing brains. Neuropathol Appl Neurobiol 2007 1.00
48 Population variation in oxidative stress and astrocyte DNA damage in relation to Alzheimer-type pathology in the ageing brain. Neuropathol Appl Neurobiol 2009 1.00
49 Changes in self-rated health, disability and contact with services in a very elderly cohort: a 6-year follow-up study. Age Ageing 1998 0.99
50 Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease. Am J Med Genet B Neuropsychiatr Genet 2007 0.98
51 The prevalence of vascular dementia in Europe: facts and fragments from 1980-1990 studies. EURODEM-Prevalence Research Group. Ann Neurol 1991 0.98
52 A Multiple Indicators Multiple Causes (MIMIC) model of Behavioural and Psychological Symptoms in Dementia (BPSD). Neurobiol Aging 2009 0.94
53 Examination of the validity of the hierarchical model of neuropathological staging in normal aging and Alzheimer's disease. Acta Neuropathol 1998 0.94
54 Vascular risk and cognitive impairment in an older, British, African-Caribbean population. J Am Geriatr Soc 2001 0.94
55 Prevalence and symptomatology of depression in older people living in institutions in England and Wales. Age Ageing 2007 0.93
56 Brain haemosiderin in older people: pathological evidence for an ischaemic origin of magnetic resonance imaging (MRI) microbleeds. Neuropathol Appl Neurobiol 2014 0.93
57 Co-occurrence of anxiety and depression amongst older adults in low- and middle-income countries: findings from the 10/66 study. Psychol Med 2011 0.93
58 Education and the risk for Alzheimer's disease: sex makes a difference. EURODEM pooled analyses. EURODEM Incidence Research Group. Am J Epidemiol 2000 0.92
59 Epidemiology of vascular dementia. Neuroepidemiology 1995 0.92
60 Cognitive function in UK community-dwelling African Caribbean elders: normative data for a test battery. Int J Geriatr Psychiatry 2001 0.90
61 The prevalence of depression in a cohort of the very elderly. J Affect Disord 1995 0.89
62 Health economic evaluation of treatments for Alzheimer's disease: impact of new diagnostic criteria. J Intern Med 2014 0.88
63 Incidence of dementia and cognitive decline in over-75s in Cambridge: overview of cohort study. Soc Psychiatry Psychiatr Epidemiol 1998 0.88
64 The BACE gene: genomic structure and candidate gene study in late-onset Alzheimer's disease. Neuroreport 2001 0.88
65 Psychosocial aetiology of chronic disease: a pragmatic approach to the assessment of lifetime affective morbidity in an EPIC component study. J Epidemiol Community Health 2000 0.87
66 Population variation in glial fibrillary acidic protein levels in brain ageing: relationship to Alzheimer-type pathology and dementia. Dement Geriatr Cogn Disord 2009 0.87
67 Apolipoprotein E genotype, vascular risk and early cognitive impairment in an African Caribbean population. Dement Geriatr Cogn Disord 2001 0.87
68 Estimation of verbal intelligence in an elderly community: a prediction analysis using a shortened NART. Br J Clin Psychol 1990 0.86
69 Examination of phosphorylated tau protein as a PHF-precursor at early stage Alzheimer's disease. Neurobiol Aging 1995 0.86
70 Screening for dementia--is it a no brainer? Int J Clin Pract 2013 0.86
71 Smoking and the brain. BMJ 2000 0.86
72 Alpha- and gamma-synuclein proteins are present in cerebrospinal fluid and are increased in aged subjects with neurodegenerative and vascular changes. Dement Geriatr Cogn Disord 2008 0.85
73 Mesial temporal astrocyte tau pathology in the MRC-CFAS ageing brain cohort. Dement Geriatr Cogn Disord 2012 0.85
74 Epidemiologic approach to the study of dementing diseases: a nested case-control study in European incidence studies of dementia. Neuroepidemiology 1992 0.85
75 Research and Alzheimer's disease: an epidemiological perspective. Psychol Med 1993 0.84
76 Biomarkers, dementia, and public health. Ann N Y Acad Sci 2009 0.84
77 An investigation of ACE as a risk factor for dementia and cognitive decline in the general population. J Med Genet 2002 0.84
78 Calcium dysregulation in relation to Alzheimer-type pathology in the ageing brain. Neuropathol Appl Neurobiol 2013 0.84
79 Association between APOE genotype, neuropathology and dementia in the older population of England and Wales. Neuropathol Appl Neurobiol 2011 0.84
80 Quantitative analysis of tau protein in paired helical filament preparations: implications for the role of tau protein phosphorylation in PHF assembly in Alzheimer's disease. Neurobiol Aging 1995 0.84
81 The tRNA(Gln) 4336 mitochondrial DNA variant is not a high penetrance mutation which predisposes to dementia before the age of 75 years. J Med Genet 1996 0.84
82 The genetic basis of Parkinson's disease. J Neurol Neurosurg Psychiatry 2002 0.84
83 Depression in the elderly: pathological study of raphe and locus ceruleus. Neuropathol Appl Neurobiol 2005 0.83
84 Suicidal thinking in community residents over eighty. Int J Geriatr Psychiatry 1997 0.83
85 Genetic association of an LBP-1c/CP2/LSF gene polymorphism with late onset Alzheimer's disease. J Med Genet 2001 0.83
86 Is Alzheimer's disease distinct from normal ageing? Lancet 1988 0.82
87 Longitudinal studies of ageing: a key role in the evidence base for improving health and quality of life in older adults. Age Ageing 2000 0.81
88 Synaptic changes in frontotemporal lobar degeneration: correlation with MAPT haplotype and APOE genotype. Neuropathol Appl Neurobiol 2011 0.81
89 Operational Definition of Active and Healthy Ageing (AHA): A Conceptual Framework. J Nutr Health Aging 2015 0.80
90 The relationship between clinical dementia and neuropathological staging (Braak) in a very elderly community sample. Eur Arch Psychiatry Clin Neurosci 1996 0.80
91 Alzheimer disease is not associated with polymorphisms in the angiotensinogen and renin genes. Am J Med Genet 2001 0.80
92 Loss of synaptophysin and synaptosomal-associated protein 25-kDa (SNAP-25) in elderly Down syndrome individuals. Neuropathol Appl Neurobiol 2007 0.79
93 Evidence that variation in the oligodendrocyte lineage transcription factor 2 (OLIG2) gene is associated with psychosis in Alzheimer's disease. Neurosci Lett 2009 0.78
94 The association between social stress and global cognitive function in a population-based study: the European Prospective Investigation into Cancer (EPIC)-Norfolk study. Psychol Med 2012 0.78
95 Lewy bodies and neuronal loss in subcortical areas and disability in non-demented older people: a population based neuropathological cohort study. BMC Geriatr 2009 0.77
96 The relationship between back pain and mortality in older adults varies with disability and gender: results from the Cambridge City over-75s Cohort (CC75C) study. Eur J Pain 2014 0.77
97 APOE and ACE polymorphisms and dementia risk in the older population over prolonged follow-up: 10 years of incidence in the MRC CFA Study. Age Ageing 2009 0.77
98 Cognitive function in UK community-dwelling African Caribbean and white elders: a pilot study. Int J Geriatr Psychiatry 2000 0.77
99 Interaction between the ADAM12 and SH3MD1 genes may confer susceptibility to late-onset Alzheimer's disease. Am J Med Genet B Neuropsychiatr Genet 2007 0.77
100 Attitudes toward death: a community study of octoagenarians and nonagenarians. Int Psychogeriatr 1997 0.76
101 Apo E and Apo CI loci are associated with dementia in younger but not older late-onset cases. Dement Geriatr Cogn Disord 1998 0.75
102 Risk prediction models: a framework for assessment. Public Health Genomics 2011 0.75
103 Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample. Am J Med Genet B Neuropsychiatr Genet 2009 0.75
104 Healthy ageing in urban and rural Britain: a comparison of exercise and diet. Age Ageing 2000 0.75
105 A longitudinal study in progress: a five-year follow-up of women aged 70-79 years living in a rural community. Neuroepidemiology 1992 0.75
106 Social support and activities of daily living in older Afro-Caribbean and white UK residents. Age Ageing 1998 0.75
107 Could boxing be banned? A legal and epidemiological perspective. BMJ 1998 0.75
108 Predictors of hospital contact by very elderly people: a pilot study from a cohort of people aged 75 years and over. Age Ageing 1995 0.75
109 Cognitive impairment: a challenge for community care. A comparison of the domiciliary service receipt of cognitively impaired and equally dependent physically impaired elderly women. Age Ageing 1997 0.75
110 Local population differences and the needs of people with cognitive impairment. Int J Geriatr Psychiatry 1997 0.75
111 Ethical Issues in the Development of Readiness Cohorts in Alzheimer's Disease Research. J Prev Alzheimers Dis 2017 0.75
112 Reemphasizing the role of fructose intake as a risk factor for dementia. J Gerontol A Biol Sci Med Sci 2011 0.75