|
1
|
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.
|
Nat Genet
|
2010
|
3.37
|
|
2
|
The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons.
|
Cell
|
2004
|
3.19
|
|
3
|
SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site.
|
Dev Cell
|
2004
|
2.74
|
|
4
|
Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain.
|
Neuron
|
2002
|
2.71
|
|
5
|
Mammalian brain morphogenesis and midline axon guidance require heparan sulfate.
|
Science
|
2003
|
2.53
|
|
6
|
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.
|
Nat Genet
|
2012
|
2.12
|
|
7
|
Sequence variation in NPC1L1 and association with improved LDL-cholesterol lowering in response to ezetimibe treatment.
|
Genomics
|
2005
|
1.32
|
|
8
|
Directional guidance of interneuron migration to the cerebral cortex relies on subcortical Slit1/2-independent repulsion and cortical attraction.
|
Development
|
2003
|
1.20
|
|
9
|
An anti-PCSK9 antibody reduces LDL-cholesterol on top of a statin and suppresses hepatocyte SREBP-regulated genes.
|
Int J Biol Sci
|
2012
|
1.15
|
|
10
|
Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.
|
Am J Hum Genet
|
2012
|
1.05
|
|
11
|
Slit1 and slit2 proteins control the development of the lateral olfactory tract.
|
J Neurosci
|
2002
|
0.93
|
|
12
|
Cholesterol in human atherosclerotic plaque is a marker for underlying disease state and plaque vulnerability.
|
Lipids Health Dis
|
2010
|
0.88
|
|
13
|
AAV8-mediated long-term expression of human LCAT significantly improves lipid profiles in hCETP;Ldlr(+/-) mice.
|
J Cardiovasc Transl Res
|
2011
|
0.87
|
|
14
|
High-throughput simultaneous analysis of RNA, protein, and lipid biomarkers in heterogeneous tissue samples.
|
Clin Chem
|
2011
|
0.85
|
|
15
|
Small molecule activation of lecithin cholesterol acyltransferase modulates lipoprotein metabolism in mice and hamsters.
|
Metabolism
|
2011
|
0.83
|
|
16
|
Differential profiles of thrombin inhibitors (heparin, hirudin, bivalirudin, and dabigatran) in the thrombin generation assay and thromboelastography in vitro.
|
Blood Coagul Fibrinolysis
|
2013
|
0.76
|