Published in Neuron on January 17, 2002
A genomic pathway approach to a complex disease: axon guidance and Parkinson disease. PLoS Genet (2007) 3.28
Tangential neuronal migration controls axon guidance: a role for neuregulin-1 in thalamocortical axon navigation. Cell (2006) 3.12
Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex. Proc Natl Acad Sci U S A (2005) 2.81
Hox paralog group 2 genes control the migration of mouse pontine neurons through slit-robo signaling. PLoS Biol (2008) 1.85
The requirement for Phr1 in CNS axon tract formation reveals the corticostriatal boundary as a choice point for cortical axons. Genes Dev (2007) 1.85
Transient neuronal populations are required to guide callosal axons: a role for semaphorin 3C. PLoS Biol (2009) 1.85
Gating of Sema3E/PlexinD1 signaling by neuropilin-1 switches axonal repulsion to attraction during brain development. Neuron (2007) 1.83
Development, specification, and diversity of callosal projection neurons. Trends Neurosci (2010) 1.70
A genetic model for a central (septum transversum) congenital diaphragmatic hernia in mice lacking Slit3. Proc Natl Acad Sci U S A (2003) 1.60
Sprouting, regeneration and circuit formation in the injured spinal cord: factors and activity. Philos Trans R Soc Lond B Biol Sci (2006) 1.48
Regeneration and maintenance of the planarian midline is regulated by a slit orthologue. Dev Biol (2007) 1.42
Repulsive axon guidance molecule Slit3 is a novel angiogenic factor. Blood (2009) 1.37
Wiring the brain: the biology of neuronal guidance. Cold Spring Harb Perspect Biol (2010) 1.33
Cellular strategies of axonal pathfinding. Cold Spring Harb Perspect Biol (2010) 1.33
NFIA haploinsufficiency is associated with a CNS malformation syndrome and urinary tract defects. PLoS Genet (2007) 1.30
Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points. Neural Dev (2008) 1.24
Axon guidance and synaptic maintenance: preclinical markers for neurodegenerative disease and therapeutics. Trends Neurosci (2009) 1.24
Dual function of Slit2 in repulsion and enhanced migration of trunk, but not vagal, neural crest cells. J Cell Biol (2003) 1.24
Development of axonal pathways in the human fetal fronto-limbic brain: histochemical characterization and diffusion tensor imaging. J Anat (2010) 1.23
Extracellular matrix: functions in the nervous system. Cold Spring Harb Perspect Biol (2011) 1.21
Pioneer longitudinal axons navigate using floor plate and Slit/Robo signals. Development (2008) 1.20
Neuropilin 1-Sema signaling regulates crossing of cingulate pioneering axons during development of the corpus callosum. Cereb Cortex (2009) 1.19
Semaphorin 3F is a bifunctional guidance cue for dopaminergic axons and controls their fasciculation, channeling, rostral growth, and intracortical targeting. J Neurosci (2009) 1.19
Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism. Genes Dev (2009) 1.17
Slit-Robo interactions during cortical development. J Anat (2007) 1.16
Netrin-DCC, Robo-Slit, and heparan sulfate proteoglycans coordinate lateral positioning of longitudinal dopaminergic diencephalospinal axons. J Neurosci (2009) 1.13
Decreased expression of axon-guidance receptors in the anterior cingulate cortex in autism. Mol Autism (2011) 1.09
cGMP-mediated signaling via cGKIalpha is required for the guidance and connectivity of sensory axons. J Cell Biol (2002) 1.05
Mechanisms controlling the guidance of thalamocortical axons through the embryonic forebrain. Eur J Neurosci (2012) 1.04
Molecules and mechanisms involved in the generation and migration of cortical interneurons. ASN Neuro (2010) 1.04
Development of the corticothalamic projections. Front Neurosci (2012) 1.04
Multiple non-cell-autonomous defects underlie neocortical callosal dysgenesis in Nfib-deficient mice. Neural Dev (2009) 1.03
Molecular determinants of the face map development in the trigeminal brainstem. Anat Rec A Discov Mol Cell Evol Biol (2006) 1.02
Neuronal migration and molecular conservation with leukocyte chemotaxis. Genes Dev (2002) 1.02
Slit/Robo signaling modulates the proliferation of central nervous system progenitors. Neuron (2012) 1.01
Flotillin-mediated endocytic events dictate cell type-specific responses to semaphorin 3A. J Neurosci (2010) 0.99
Midbrain dopaminergic axons are guided longitudinally through the diencephalon by Slit/Robo signals. Mol Cell Neurosci (2010) 0.99
Slit2, a branching-arborization factor for sensory axons in the Mammalian CNS. J Neurosci (2002) 0.98
The corticofugal neuron-associated genes ROBO1, SRGAP1, and CTIP2 exhibit an anterior to posterior gradient of expression in early fetal human neocortex development. Cereb Cortex (2010) 0.98
Development and malformations of the human pyramidal tract. J Neurol (2004) 0.98
A forward genetic screen with a thalamocortical axon reporter mouse yields novel neurodevelopment mutants and a distinct emx2 mutant phenotype. Neural Dev (2011) 0.97
A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation. Neuron (2012) 0.96
Developmental guidance of embryonic corneal innervation: roles of Semaphorin3A and Slit2. Dev Biol (2010) 0.96
Sonic hedgehog is a chemoattractant for midbrain dopaminergic axons. PLoS One (2009) 0.95
Axon position within the corpus callosum determines contralateral cortical projection. Proc Natl Acad Sci U S A (2013) 0.95
Slits are chemorepellents endogenous to hypothalamus and steer thalamocortical axons into ventral telencephalon. Cereb Cortex (2009) 0.94
Pax6 guides a relay of pioneer longitudinal axons in the embryonic mouse forebrain. J Comp Neurol (2004) 0.94
Globularity and language-readiness: generating new predictions by expanding the set of genes of interest. Front Psychol (2014) 0.94
Dorsal turning of motor corticospinal axons at the pyramidal decussation requires plexin signaling. Neural Dev (2008) 0.94
What can we get from 'barrels': the rodent barrel cortex as a model for studying the establishment of neural circuits. Eur J Neurosci (2011) 0.93
Spontaneous activity regulates Robo1 transcription to mediate a switch in thalamocortical axon growth. Nat Neurosci (2012) 0.92
Gbx2 regulates thalamocortical axon guidance by modifying the LIM and Robo codes. Development (2012) 0.91
Semaphorin 3A inactivation suppresses ischemia-reperfusion-induced inflammation and acute kidney injury. Am J Physiol Renal Physiol (2014) 0.91
The atypical homeoprotein Pbx1a participates in the axonal pathfinding of mesencephalic dopaminergic neurons. Neural Dev (2012) 0.90
Expression by midbrain dopamine neurons of Sema3A and 3F receptors is associated with chemorepulsion in vitro but a mild in vivo phenotype. Mol Cell Neurosci (2010) 0.90
The Slit receptor Robo1 is predominantly expressed via the Dutt1 alternative promoter in pioneer neurons in the embryonic mouse brain and spinal cord. Gene Expr Patterns (2007) 0.89
Development and specification of GABAergic cortical interneurons. Cell Biosci (2013) 0.89
Distinguishing between directional guidance and motility regulation in neuronal migration. J Neurosci (2003) 0.89
Reduced DEAF1 function during type 1 diabetes inhibits translation in lymph node stromal cells by suppressing Eif4g3. J Mol Cell Biol (2012) 0.89
Subset specification of central serotonergic neurons. Front Cell Neurosci (2013) 0.88
RabGDI controls axonal midline crossing by regulating Robo1 surface expression. Neural Dev (2012) 0.88
Dopaminergic axon guidance: which makes what? Front Cell Neurosci (2012) 0.88
Ephrin-A5 regulates the formation of the ascending midbrain dopaminergic pathways. Dev Neurobiol (2009) 0.88
Development and function of the midbrain dopamine system: what we know and what we need to. Genes Brain Behav (2015) 0.87
Brain evolution by brain pathway duplication. Philos Trans R Soc Lond B Biol Sci (2015) 0.87
Evidence that descending cortical axons are essential for thalamocortical axons to cross the pallial-subpallial boundary in the embryonic forebrain. PLoS One (2012) 0.87
The role of Robo3 in the development of cortical interneurons. Cereb Cortex (2009) 0.86
Pioneer midbrain longitudinal axons navigate using a balance of Netrin attraction and Slit repulsion. Neural Dev (2014) 0.86
Guidance of longitudinally projecting axons in the developing central nervous system. Front Mol Neurosci (2012) 0.85
The importance of combinatorial gene expression in early Mammalian thalamic patterning and thalamocortical axonal guidance. Front Neurosci (2012) 0.85
EphB receptor forward signaling regulates area-specific reciprocal thalamic and cortical axon pathfinding. Proc Natl Acad Sci U S A (2014) 0.84
Slit-Robo signals regulate pioneer axon pathfinding of the tract of the postoptic commissure in the mammalian forebrain. J Neurosci Res (2011) 0.84
Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning. Cereb Cortex (2012) 0.84
Disrupted prefrontal interhemispheric structural coupling in schizophrenia related to working memory performance. Schizophr Bull (2013) 0.83
Midline crossing is not required for subsequent pathfinding decisions in commissural neurons. Neural Dev (2012) 0.83
Longitudinal axons are guided by Slit/Robo signals from the floor plate. Cell Adh Migr (2010) 0.83
Robo1 modulates proliferation and neurogenesis in the developing neocortex. J Neurosci (2014) 0.83
Dyslexia-associated kiaa0319-like protein interacts with axon guidance receptor nogo receptor 1. Cell Mol Neurobiol (2010) 0.83
G-protein-coupled receptor cell signaling pathways mediating embryonic chick retinal growth cone collapse induced by lysophosphatidic acid and sphingosine-1-phosphate. Dev Neurosci (2014) 0.83
Sonic hedgehog and Wnt: antagonists in morphogenesis but collaborators in axon guidance. Front Cell Neurosci (2013) 0.82
Axon responses of embryonic stem cell-derived dopaminergic neurons to semaphorins 3A and 3C. J Neurosci Res (2010) 0.82
Crosstalk between intracellular and extracellular signals regulating interneuron production, migration and integration into the cortex. Front Cell Neurosci (2015) 0.81
Heparan sulfotransferases Hs6st1 and Hs2st keep Erk in check for mouse corpus callosum development. J Neurosci (2014) 0.81
Development of posterior hypothalamic neurons enlightens a switch in the prosencephalic basic plan. PLoS One (2011) 0.81
Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signalling. Nat Commun (2014) 0.81
Strategies for regenerating injured axons after spinal cord injury - insights from brain development. Biologics (2008) 0.80
Mutations in the ROBO2 and SLIT2 genes are rare causes of familial vesico-ureteral reflux. Pediatr Nephrol (2009) 0.80
Alternatively spliced Robo2 isoforms in zebrafish and rat. Dev Genes Evol (2006) 0.80
Agenesis of the Corpus Callosum Due to Defective Glial Wedge Formation in Lhx2 Mutant Mice. Cereb Cortex (2014) 0.79
Prefrontal-enriched SLIT1 expression in Old World monkey cortex established during the postnatal development. Cereb Cortex (2010) 0.79
Abundant expression of guidance and synaptogenic molecules in the injured spinal cord. PLoS One (2014) 0.79
The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap. Development (2014) 0.79
The expression and activity of β-catenin in the thalamus and its projections to the cerebral cortex in the mouse embryo. BMC Neurosci (2012) 0.79
Surrounded by Slit--how forebrain commissural axons can be led astray. Neuron (2002) 0.78
Axon guidance mechanisms for establishment of callosal connections. Neural Plast (2013) 0.78
Astroglial-Mediated Remodeling of the Interhemispheric Midline Is Required for the Formation of the Corpus Callosum. Cell Rep (2016) 0.78
The expression pattern of EVA1C, a novel Slit receptor, is consistent with an axon guidance role in the mouse nervous system. PLoS One (2013) 0.77
Cooperative slit and netrin signaling in contralateralization of the mouse trigeminothalamic pathway. J Comp Neurol (2013) 0.77
Lateral neuron--glia interactions steer the response of axons to the Robo code. Neuron Glia Biol (2004) 0.77
Neuronal and microglial regulators of cortical wiring: usual and novel guideposts. Front Neurosci (2015) 0.77
APP binds DR6 to trigger axon pruning and neuron death via distinct caspases. Nature (2009) 6.17
Cortical excitatory neurons and glia, but not GABAergic neurons, are produced in the Emx1-expressing lineage. J Neurosci (2002) 5.68
Common mechanisms of nerve and blood vessel wiring. Nature (2005) 5.46
Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes. Nature (2010) 5.11
Cell migration in the forebrain. Annu Rev Neurosci (2003) 4.59
Mice lacking Dlx1 show subtype-specific loss of interneurons, reduced inhibition and epilepsy. Nat Neurosci (2005) 4.18
Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling. Science (2003) 4.18
Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth. Cancer Cell (2007) 4.11
New neurons follow the flow of cerebrospinal fluid in the adult brain. Science (2006) 3.98
A public gene trap resource for mouse functional genomics. Nat Genet (2004) 3.96
Developmental functions of the Distal-less/Dlx homeobox genes. Development (2002) 3.89
PirB is a functional receptor for myelin inhibitors of axonal regeneration. Science (2008) 3.86
The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system. Nature (2004) 3.77
dSarm/Sarm1 is required for activation of an injury-induced axon death pathway. Science (2012) 3.72
The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance. Cell (2003) 3.66
Forebrain gene expression domains and the evolving prosomeric model. Trends Neurosci (2003) 3.64
Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function. Nature (2003) 3.42
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
Specification of jaw subdivisions by Dlx genes. Science (2002) 3.33
Patterning and plasticity of the cerebral cortex. Science (2005) 3.30
Delineation of multiple subpallial progenitor domains by the combinatorial expression of transcriptional codes. J Neurosci (2007) 3.28
Lack of enhanced spinal regeneration in Nogo-deficient mice. Neuron (2003) 3.22
The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons. Cell (2004) 3.19
Tangential neuronal migration controls axon guidance: a role for neuregulin-1 in thalamocortical axon navigation. Cell (2006) 3.12
PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates. Nature (2004) 3.10
Conserved roles for Slit and Robo proteins in midline commissural axon guidance. Neuron (2004) 2.94
Spatial genetic patterning of the embryonic neuroepithelium generates GABAergic interneuron diversity in the adult cortex. J Neurosci (2007) 2.90
Regeneration of sensory axons within the injured spinal cord induced by intraganglionic cAMP elevation. Neuron (2002) 2.84
Dlx transcription factors promote migration through repression of axon and dendrite growth. Neuron (2007) 2.79
Slit1 and Slit2 cooperate to prevent premature midline crossing of retinal axons in the mouse visual system. Neuron (2002) 2.77
SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site. Dev Cell (2004) 2.74
Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development. Cell Stem Cell (2013) 2.74
CXCR4 and CXCR7 have distinct functions in regulating interneuron migration. Neuron (2011) 2.69
New insights into the classification and nomenclature of cortical GABAergic interneurons. Nat Rev Neurosci (2013) 2.65
Mechanisms and molecules of neuronal wiring: a primer. Cold Spring Harb Perspect Biol (2011) 2.62
Regulatory roles of conserved intergenic domains in vertebrate Dlx bigene clusters. Genome Res (2003) 2.57
Regulation of cortical dendrite development by Slit-Robo interactions. Neuron (2002) 2.55
Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons. Cell (2003) 2.54
Mammalian brain morphogenesis and midline axon guidance require heparan sulfate. Science (2003) 2.53
Short- and long-range attraction of cortical GABAergic interneurons by neuregulin-1. Neuron (2004) 2.51
Control of cortical GABA circuitry development by Nrg1 and ErbB4 signalling. Nature (2010) 2.51
EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans. Science (2005) 2.50
Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers. Development (2006) 2.50
Retinoic acid from the meninges regulates cortical neuron generation. Cell (2009) 2.46
Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex. Proc Natl Acad Sci U S A (2010) 2.45
Blocking neuropilin-2 function inhibits tumor cell metastasis. Cancer Cell (2008) 2.35
The chemokine SDF1 regulates migration of dentate granule cells. Development (2002) 2.34
Pax6 is required for making specific subpopulations of granule and periglomerular neurons in the olfactory bulb. J Neurosci (2005) 2.34
A high-resolution enhancer atlas of the developing telencephalon. Cell (2013) 2.34
False resurrections: distinguishing regenerated from spared axons in the injured central nervous system. J Comp Neurol (2003) 2.34
Alternative splicing of the Robo3 axon guidance receptor governs the midline switch from attraction to repulsion. Neuron (2008) 2.33
Boc is a receptor for sonic hedgehog in the guidance of commissural axons. Nature (2006) 2.29
Genetic deletion of the Nogo receptor does not reduce neurite inhibition in vitro or promote corticospinal tract regeneration in vivo. Proc Natl Acad Sci U S A (2005) 2.27
Dlx1 and Dlx2 control neuronal versus oligodendroglial cell fate acquisition in the developing forebrain. Neuron (2007) 2.23
Aberrant seizure-induced neurogenesis in experimental temporal lobe epilepsy. Ann Neurol (2006) 2.22
Cyclic AMP/GMP-dependent modulation of Ca2+ channels sets the polarity of nerve growth-cone turning. Nature (2003) 2.18
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet (2012) 2.12
New neurons clear the path of astrocytic processes for their rapid migration in the adult brain. Neuron (2010) 2.12
Regeneration of the adult central nervous system. Curr Biol (2005) 2.11
Ectopic expression of the Dlx genes induces glutamic acid decarboxylase and Dlx expression. Development (2002) 2.10
Distinct molecular pathways for development of telencephalic interneuron subtypes revealed through analysis of Lhx6 mutants. J Comp Neurol (2008) 2.09
Recognition of the neural chemoattractant Netrin-1 by integrins alpha6beta4 and alpha3beta1 regulates epithelial cell adhesion and migration. Dev Cell (2003) 2.08
Cortical inhibition modified by embryonic neural precursors grafted into the postnatal brain. J Neurosci (2006) 2.08
Reduction of seizures by transplantation of cortical GABAergic interneuron precursors into Kv1.1 mutant mice. Proc Natl Acad Sci U S A (2009) 2.06
Structure of the Nogo receptor ectodomain: a recognition module implicated in myelin inhibition. Neuron (2003) 2.06
The Nogo-66 receptor NgR1 is required only for the acute growth cone-collapsing but not the chronic growth-inhibitory actions of myelin inhibitors. J Neurosci (2007) 2.06
Molecular regionalization of the neocortex is disrupted in Fgf8 hypomorphic mutants. Development (2003) 2.04
Beyond laminar fate: toward a molecular classification of cortical projection/pyramidal neurons. Dev Neurosci (2003) 2.02
Autism and brain development. Cell (2008) 2.01
DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1. Cell (2008) 1.97
Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon. Development (2002) 1.95
The netrin receptor UNC-40/DCC stimulates axon attraction and outgrowth through enabled and, in parallel, Rac and UNC-115/AbLIM. Neuron (2003) 1.95
A subpopulation of olfactory bulb GABAergic interneurons is derived from Emx1- and Dlx5/6-expressing progenitors. J Neurosci (2007) 1.94
Netrin-1-mediated axon outgrowth requires deleted in colorectal cancer-dependent MAPK activation. Nature (2002) 1.94
Reassessing the Dlx code: the genetic regulation of branchial arch skeletal pattern and development. J Anat (2005) 1.93
Stereotyped pruning of long hippocampal axon branches triggered by retraction inducers of the semaphorin family. Cell (2003) 1.92
Frontal cortex subdivision patterning is coordinately regulated by Fgf8, Fgf17, and Emx2. J Comp Neurol (2008) 1.90
Differential requirement for Plexin-A3 and -A4 in mediating responses of sensory and sympathetic neurons to distinct class 3 Semaphorins. Neuron (2005) 1.89
Dlx1&2-dependent expression of Zfhx1b (Sip1, Zeb2) regulates the fate switch between cortical and striatal interneurons. Neuron (2013) 1.87
Novel brain wiring functions for classical morphogens: a role as graded positional cues in axon guidance. Development (2005) 1.86
Activation of the UNC5B receptor by Netrin-1 inhibits sprouting angiogenesis. Genes Dev (2007) 1.86
The LIM-homeobox gene Lhx8 is required for the development of many cholinergic neurons in the mouse forebrain. Proc Natl Acad Sci U S A (2003) 1.85
Chemokine signaling controls intracortical migration and final distribution of GABAergic interneurons. J Neurosci (2008) 1.82
The embryonic preoptic area is a novel source of cortical GABAergic interneurons. J Neurosci (2009) 1.81
Distinct actions of Emx1, Emx2, and Pax6 in regulating the specification of areas in the developing neocortex. J Neurosci (2002) 1.81