Published in Mol Cell on January 01, 2002
A small RNA regulates the expression of genes involved in iron metabolism in Escherichia coli. Proc Natl Acad Sci U S A (2002) 7.99
Coupled degradation of a small regulatory RNA and its mRNA targets in Escherichia coli. Genes Dev (2003) 7.33
Signal transduction and regulatory mechanisms involved in control of the sigma(S) (RpoS) subunit of RNA polymerase. Microbiol Mol Biol Rev (2002) 5.60
Deep sequencing analysis of small noncoding RNA and mRNA targets of the global post-transcriptional regulator, Hfq. PLoS Genet (2008) 5.23
Hfq and its constellation of RNA. Nat Rev Microbiol (2011) 4.94
Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like protein. EMBO J (2002) 3.88
Hfq, a new chaperoning role: binding to messenger RNA determines access for small RNA regulator. EMBO J (2004) 3.75
Quantitative characteristics of gene regulation by small RNA. PLoS Biol (2007) 3.35
Structure of Escherichia coli Hfq bound to polyriboadenylate RNA. Proc Natl Acad Sci U S A (2009) 3.04
Staphylococcus aureus RNAIII and the endoribonuclease III coordinately regulate spa gene expression. EMBO J (2005) 2.95
Hfq-dependent regulation of OmpA synthesis is mediated by an antisense RNA. Genes Dev (2005) 2.93
Target prediction for small, noncoding RNAs in bacteria. Nucleic Acids Res (2006) 2.90
GadY, a small-RNA regulator of acid response genes in Escherichia coli. J Bacteriol (2004) 2.89
Escherichia coli Hfq has distinct interaction surfaces for DsrA, rpoS and poly(A) RNAs. Nat Struct Mol Biol (2004) 2.79
Spot 42 RNA mediates discoordinate expression of the E. coli galactose operon. Genes Dev (2002) 2.75
Two seemingly homologous noncoding RNAs act hierarchically to activate glmS mRNA translation. PLoS Biol (2008) 2.61
Coincident Hfq binding and RNase E cleavage sites on mRNA and small regulatory RNAs. RNA (2003) 2.57
MicC, a second small-RNA regulator of Omp protein expression in Escherichia coli. J Bacteriol (2004) 2.53
Ribozymes, riboswitches and beyond: regulation of gene expression without proteins. Nat Rev Genet (2007) 2.52
The RNA-binding protein Hfq of Listeria monocytogenes: role in stress tolerance and virulence. J Bacteriol (2004) 2.34
Multiple small RNAs act additively to integrate sensory information and control quorum sensing in Vibrio harveyi. Genes Dev (2007) 2.33
Identification of the Hfq-binding site on DsrA RNA: Hfq binds without altering DsrA secondary structure. RNA (2003) 2.31
Small RNA regulators and the bacterial response to stress. Cold Spring Harb Symp Quant Biol (2006) 2.31
The rpoS mRNA leader recruits Hfq to facilitate annealing with DsrA sRNA. RNA (2008) 2.27
Coding sequence targeting by MicC RNA reveals bacterial mRNA silencing downstream of translational initiation. Nat Struct Mol Biol (2009) 2.25
Positive regulation by small RNAs and the role of Hfq. Proc Natl Acad Sci U S A (2010) 2.23
Base pairing small RNAs and their roles in global regulatory networks. FEMS Microbiol Rev (2010) 2.13
RNA chaperone activity of the Sm-like Hfq protein. EMBO Rep (2003) 2.13
Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing. Genes Dev (2003) 2.10
Predicted structure and phyletic distribution of the RNA-binding protein Hfq. Nucleic Acids Res (2002) 2.01
Detection of non-coding RNAs on the basis of predicted secondary structure formation free energy change. BMC Bioinformatics (2006) 2.01
The poly(A) binding protein Hfq protects RNA from RNase E and exoribonucleolytic degradation. Nucleic Acids Res (2003) 2.00
Identification of small Hfq-binding RNAs in Listeria monocytogenes. RNA (2006) 2.00
Sm-like proteins in Eubacteria: the crystal structure of the Hfq protein from Escherichia coli. Nucleic Acids Res (2003) 1.91
RNAs actively cycle on the Sm-like protein Hfq. Genes Dev (2010) 1.84
Both RNase E and RNase III control the stability of sodB mRNA upon translational inhibition by the small regulatory RNA RyhB. Nucleic Acids Res (2005) 1.80
Caught at its own game: regulatory small RNA inactivated by an inducible transcript mimicking its target. Genes Dev (2009) 1.78
The challenge of regulation in a minimal photoautotroph: non-coding RNAs in Prochlorococcus. PLoS Genet (2008) 1.74
An antibody-based microarray assay for small RNA detection. Nucleic Acids Res (2006) 1.65
Impact of the RNA chaperone Hfq on the fitness and virulence potential of uropathogenic Escherichia coli. Infect Immun (2008) 1.65
PolyU tail of rho-independent terminator of bacterial small RNAs is essential for Hfq action. Proc Natl Acad Sci U S A (2011) 1.64
The 5' end of two redundant sRNAs is involved in the regulation of multiple targets, including their own regulator. Nucleic Acids Res (2008) 1.63
Bacterial small RNA-based negative regulation: Hfq and its accomplices. J Biol Chem (2013) 1.63
Characterization of the small untranslated RNA RyhB and its regulon in Vibrio cholerae. J Bacteriol (2005) 1.60
RNA misfolding and the action of chaperones. Front Biosci (2008) 1.59
Dissecting RNA chaperone activity. RNA (2007) 1.55
The C-terminal domain of Escherichia coli Hfq is required for regulation. Nucleic Acids Res (2007) 1.55
A La protein requirement for efficient pre-tRNA folding. EMBO J (2003) 1.55
The decapping activator Lsm1p-7p-Pat1p complex has the intrinsic ability to distinguish between oligoadenylated and polyadenylated RNAs. RNA (2007) 1.54
Yeast Lsm1p-7p/Pat1p deadenylation-dependent mRNA-decapping factors are required for brome mosaic virus genomic RNA translation. Mol Cell Biol (2003) 1.54
Long-distance RNA-RNA interactions in plant virus gene expression and replication. Annu Rev Phytopathol (2006) 1.53
Small RNA binding to the lateral surface of Hfq hexamers and structural rearrangements upon mRNA target recognition. Proc Natl Acad Sci U S A (2012) 1.51
Disruption of small RNA signaling caused by competition for Hfq. Proc Natl Acad Sci U S A (2010) 1.51
Transcriptomic and metabolomic profiling of Zymomonas mobilis during aerobic and anaerobic fermentations. BMC Genomics (2009) 1.44
Spectroscopic observation of RNA chaperone activities of Hfq in post-transcriptional regulation by a small non-coding RNA. Nucleic Acids Res (2007) 1.41
In vitro analysis of the interaction between the small RNA SR1 and its primary target ahrC mRNA. Nucleic Acids Res (2007) 1.36
Hfq, a novel pleiotropic regulator of virulence-associated genes in Francisella tularensis. Infect Immun (2009) 1.36
The RNA binding protein Hfq interacts specifically with tRNAs. RNA (2008) 1.35
snRNAs contain specific SMN-binding domains that are essential for snRNP assembly. Mol Cell Biol (2004) 1.34
RNA under attack: cellular handling of RNA damage. Crit Rev Biochem Mol Biol (2009) 1.32
Small non-coding RNAs in Streptomyces coelicolor. Nucleic Acids Res (2008) 1.31
Constitutive activation of the Escherichia coli Pho regulon upregulates rpoS translation in an Hfq-dependent fashion. J Bacteriol (2003) 1.30
Structural insights into the dynamics and function of the C-terminus of the E. coli RNA chaperone Hfq. Nucleic Acids Res (2011) 1.30
Rapid binding and release of Hfq from ternary complexes during RNA annealing. Nucleic Acids Res (2011) 1.30
RNA, but not protein partners, is directly responsible for translational silencing by a bacterial Hfq-binding small RNA. Proc Natl Acad Sci U S A (2008) 1.28
Genomic SELEX for Hfq-binding RNAs identifies genomic aptamers predominantly in antisense transcripts. Nucleic Acids Res (2010) 1.27
RNase E-dependent processing stabilizes MicX, a Vibrio cholerae sRNA. Mol Microbiol (2007) 1.26
Defining a role for Hfq in Gram-positive bacteria: evidence for Hfq-dependent antisense regulation in Listeria monocytogenes. Nucleic Acids Res (2009) 1.25
Translational autocontrol of the Escherichia coli hfq RNA chaperone gene. RNA (2005) 1.25
The small RNA chaperone Hfq is required for the virulence of Yersinia pseudotuberculosis. Infect Immun (2010) 1.25
RNA chaperone StpA loosens interactions of the tertiary structure in the td group I intron in vivo. Genes Dev (2002) 1.23
Mutations in interaction surfaces differentially impact E. coli Hfq association with small RNAs and their mRNA targets. J Mol Biol (2013) 1.23
Cycling of RNAs on Hfq. RNA Biol (2013) 1.22
Major role for mRNA binding and restructuring in sRNA recruitment by Hfq. RNA (2011) 1.20
Lsm proteins are required for normal processing of pre-tRNAs and their efficient association with La-homologous protein Lhp1p. Mol Cell Biol (2002) 1.20
An upstream Hfq binding site in the fhlA mRNA leader region facilitates the OxyS-fhlA interaction. PLoS One (2010) 1.20
Conserved arginines on the rim of Hfq catalyze base pair formation and exchange. Nucleic Acids Res (2013) 1.19
Translational regulation of gene expression by an anaerobically induced small non-coding RNA in Escherichia coli. J Biol Chem (2010) 1.19
Taming free energy landscapes with RNA chaperones. RNA Biol (2010) 1.19
Nuclear pre-mRNA decapping and 5' degradation in yeast require the Lsm2-8p complex. Mol Cell Biol (2004) 1.19
Effect of salt and RNA structure on annealing and strand displacement by Hfq. Nucleic Acids Res (2009) 1.18
Noncanonical repression of translation initiation through small RNA recruitment of the RNA chaperone Hfq. Genes Dev (2012) 1.16
FinO is an RNA chaperone that facilitates sense-antisense RNA interactions. EMBO J (2003) 1.13
Identification and function of the RNA chaperone Hfq in the Lyme disease spirochete Borrelia burgdorferi. Mol Microbiol (2010) 1.12
Identification of chromosomal alpha-proteobacterial small RNAs by comparative genome analysis and detection in Sinorhizobium meliloti strain 1021. BMC Genomics (2007) 1.11
Quantifying the sequence-function relation in gene silencing by bacterial small RNAs. Proc Natl Acad Sci U S A (2011) 1.11
Hfq proximity and orientation controls RNA annealing. Nucleic Acids Res (2012) 1.11
The stoichiometry of the Escherichia coli Hfq protein bound to RNA. RNA (2011) 1.10
Alternative Hfq-sRNA interaction modes dictate alternative mRNA recognition. EMBO J (2015) 1.08
Hfq affects the expression of the LEE pathogenicity island in enterohaemorrhagic Escherichia coli. Mol Microbiol (2009) 1.08
Specific sequence features, recognized by the SMN complex, identify snRNAs and determine their fate as snRNPs. Mol Cell Biol (2005) 1.07
Small RNAs in the control of RpoS, CsgD, and biofilm architecture of Escherichia coli. RNA Biol (2014) 1.07
An Hfq-like protein in archaea: crystal structure and functional characterization of the Sm protein from Methanococcus jannaschii. RNA (2007) 1.07
Archaeal and eukaryotic homologs of Hfq: A structural and evolutionary perspective on Sm function. RNA Biol (2013) 1.07
Dynamic competition of DsrA and rpoS fragments for the proximal binding site of Hfq as a means for efficient annealing. Nucleic Acids Res (2011) 1.06
RNase E action at a distance: degradation of target mRNAs mediated by an Hfq-binding small RNA in bacteria. Genes Dev (2011) 1.06
Lsm proteins and Hfq: Life at the 3' end. RNA Biol (2013) 1.05
Crystal structure of Hfq from Bacillus subtilis in complex with SELEX-derived RNA aptamer: insight into RNA-binding properties of bacterial Hfq. Nucleic Acids Res (2011) 1.05
The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs). Protein Sci (2003) 1.05
Regulatory RNAs in bacteria. Cell (2009) 9.57
Global analysis of small RNA and mRNA targets of Hfq. Mol Microbiol (2003) 4.98
Regulation by small RNAs in bacteria: expanding frontiers. Mol Cell (2011) 4.68
Outcome of the first electron microscopy validation task force meeting. Structure (2012) 4.35
An abundance of RNA regulators. Annu Rev Biochem (2005) 4.08
Three-dimensional structure of herpes simplex virus from cryo-electron tomography. Science (2003) 3.82
Bacterial small RNA regulators: versatile roles and rapidly evolving variations. Cold Spring Harb Perspect Biol (2011) 3.75
Influenza virus pleiomorphy characterized by cryoelectron tomography. Proc Natl Acad Sci U S A (2006) 3.25
Target prediction for small, noncoding RNAs in bacteria. Nucleic Acids Res (2006) 2.90
GadY, a small-RNA regulator of acid response genes in Escherichia coli. J Bacteriol (2004) 2.89
Dynamics of herpes simplex virus capsid maturation visualized by time-lapse cryo-electron microscopy. Nat Struct Biol (2003) 2.78
A suf operon requirement for Fe-S cluster assembly during iron starvation in Escherichia coli. Mol Microbiol (2004) 2.66
Detection of 5'- and 3'-UTR-derived small RNAs and cis-encoded antisense RNAs in Escherichia coli. Nucleic Acids Res (2005) 2.58
Structural and functional similarities between the capsid proteins of bacteriophages T4 and HK97 point to a common ancestry. Proc Natl Acad Sci U S A (2005) 2.53
MicC, a second small-RNA regulator of Omp protein expression in Escherichia coli. J Bacteriol (2004) 2.53
Bacterial antisense RNAs: how many are there, and what are they doing? Annu Rev Genet (2010) 2.47
Small toxic proteins and the antisense RNAs that repress them. Microbiol Mol Biol Rev (2008) 2.42
Arrangement of L2 within the papillomavirus capsid. J Virol (2008) 2.37
Structural engineering of a phage lysin that targets gram-negative pathogens. Proc Natl Acad Sci U S A (2012) 2.36
Structure and polymorphism of the UL6 portal protein of herpes simplex virus type 1. J Virol (2004) 2.35
Functional architecture of the retromer cargo-recognition complex. Nature (2007) 2.26
The base-pairing RNA spot 42 participates in a multioutput feedforward loop to help enact catabolite repression in Escherichia coli. Mol Cell (2011) 2.23
The structure of the poliovirus 135S cell entry intermediate at 10-angstrom resolution reveals the location of an externalized polypeptide that binds to membranes. J Virol (2005) 2.20
Base pairing small RNAs and their roles in global regulatory networks. FEMS Microbiol Rev (2010) 2.13
An antisense RNA controls synthesis of an SOS-induced toxin evolved from an antitoxin. Mol Microbiol (2007) 2.11
Modulating the outer membrane with small RNAs. Genes Dev (2006) 2.00
Redox regulation of OxyR requires specific disulfide bond formation involving a rapid kinetic reaction path. Nat Struct Mol Biol (2004) 1.99
The SufE protein and the SufBCD complex enhance SufS cysteine desulfurase activity as part of a sulfur transfer pathway for Fe-S cluster assembly in Escherichia coli. J Biol Chem (2003) 1.97
Allosteric signaling and a nuclear exit strategy: binding of UL25/UL17 heterodimers to DNA-Filled HSV-1 capsids. Mol Cell (2007) 1.96
Abundance of type I toxin-antitoxin systems in bacteria: searches for new candidates and discovery of novel families. Nucleic Acids Res (2010) 1.93
A highly conserved 6S RNA structure is required for regulation of transcription. Nat Struct Mol Biol (2005) 1.93
Computational resources for cryo-electron tomography in Bsoft. J Struct Biol (2007) 1.87
A resolution criterion for electron tomography based on cross-validation. J Struct Biol (2005) 1.85
Repression of small toxic protein synthesis by the Sib and OhsC small RNAs. Mol Microbiol (2008) 1.85
Small membrane proteins found by comparative genomics and ribosome binding site models. Mol Microbiol (2008) 1.84
Prominent roles of the NorR and Fur regulators in the Escherichia coli transcriptional response to reactive nitrogen species. Proc Natl Acad Sci U S A (2004) 1.81
Visualization of a missing link in retrovirus capsid assembly. Nature (2009) 1.75
Characterization of beta-sheet structure in Ure2p1-89 yeast prion fibrils by solid-state nuclear magnetic resonance. Biochemistry (2007) 1.73
Membrane curvature induction and tubulation are common features of synucleins and apolipoproteins. J Biol Chem (2010) 1.69
Discovery of Fur binding site clusters in Escherichia coli by information theory models. Nucleic Acids Res (2007) 1.67
Architecture of Ure2p prion filaments: the N-terminal domains form a central core fiber. J Biol Chem (2003) 1.66
An antibody-based microarray assay for small RNA detection. Nucleic Acids Res (2006) 1.65
High-resolution mass spectrometry of viral assemblies: molecular composition and stability of dimorphic hepatitis B virus capsids. Proc Natl Acad Sci U S A (2008) 1.64
Visualization of the herpes simplex virus portal in situ by cryo-electron tomography. Virology (2006) 1.63
A model for Ure2p prion filaments and other amyloids: the parallel superpleated beta-structure. Proc Natl Acad Sci U S A (2004) 1.62
6S RNA function enhances long-term cell survival. J Bacteriol (2004) 1.61
Mechanism of inactivation on prion conversion of the Saccharomyces cerevisiae Ure2 protein. Proc Natl Acad Sci U S A (2002) 1.61
A novel class of herpesvirus with bivalve hosts. J Gen Virol (2005) 1.60
The parallel superpleated beta-structure as a model for amyloid fibrils of human amylin. J Mol Biol (2005) 1.56
A small RNA that regulates motility and biofilm formation in response to changes in nutrient availability in Escherichia coli. Mol Microbiol (2012) 1.53
Implications of the HIV-1 Rev dimer structure at 3.2 A resolution for multimeric binding to the Rev response element. Proc Natl Acad Sci U S A (2010) 1.51
Structural basis for iron piracy by pathogenic Neisseria. Nature (2012) 1.50
RNase III participates in GadY-dependent cleavage of the gadX-gadW mRNA. J Mol Biol (2010) 1.50
Structural basis for redox regulation of Yap1 transcription factor localization. Nature (2004) 1.50
Acyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: A model for the ClpX/ClpA-bound state of ClpP. Chem Biol (2010) 1.48
Reprogramming of anaerobic metabolism by the FnrS small RNA. Mol Microbiol (2010) 1.46
Beta-rolls, beta-helices, and other beta-solenoid proteins. Adv Protein Chem (2006) 1.37
Beta arcades: recurring motifs in naturally occurring and disease-related amyloid fibrils. FASEB J (2009) 1.37
Mass analysis by scanning transmission electron microscopy and electron diffraction validate predictions of stacked beta-solenoid model of HET-s prion fibrils. J Biol Chem (2006) 1.36
An expanding universe of small proteins. Curr Opin Microbiol (2011) 1.35
Small stress response proteins in Escherichia coli: proteins missed by classical proteomic studies. J Bacteriol (2010) 1.34
Yeast Rvb1 and Rvb2 are ATP-dependent DNA helicases that form a heterohexameric complex. J Mol Biol (2008) 1.34
HIV-1 maturation inhibitor bevirimat stabilizes the immature Gag lattice. J Virol (2010) 1.33
Maturation of flaviviruses starts from one or more icosahedrally independent nucleation centres. EMBO Rep (2011) 1.31
Structural changes in Influenza virus at low pH characterized by cryo-electron tomography. J Virol (2012) 1.30
Prospects of electron cryotomography to visualize macromolecular complexes inside cellular compartments: implications of crowding. Biophys Chem (2003) 1.30
Promoter specificity for 6S RNA regulation of transcription is determined by core promoter sequences and competition for region 4.2 of sigma70. Mol Microbiol (2008) 1.29
Small RNAs and small proteins involved in resistance to cell envelope stress and acid shock in Escherichia coli: analysis of a bar-coded mutant collection. J Bacteriol (2010) 1.29
The morphogenic linker peptide of HBV capsid protein forms a mobile array on the interior surface. EMBO J (2002) 1.29
Rvb1-Rvb2: essential ATP-dependent helicases for critical complexes. Biochem Cell Biol (2010) 1.29
mtCLIC/CLIC4, an organellular chloride channel protein, is increased by DNA damage and participates in the apoptotic response to p53. Mol Cell Biol (2002) 1.28
Multiple factors dictate target selection by Hfq-binding small RNAs. EMBO J (2012) 1.27
An externalized polypeptide partitions between two distinct sites on genome-released poliovirus particles. J Virol (2011) 1.26
Electron microscopic evidence in support of alpha-solenoid models of proteasomal subunits Rpn1 and Rpn2. J Mol Biol (2009) 1.25
Control of crosslinking by quaternary structure changes during bacteriophage HK97 maturation. Mol Cell (2004) 1.25
Functional proteolytic complexes of the human mitochondrial ATP-dependent protease, hClpXP. J Biol Chem (2002) 1.24
Human immunodeficiency virus type 1 N-terminal capsid mutants containing cores with abnormally high levels of capsid protein and virtually no reverse transcriptase. J Virol (2003) 1.24
Time-resolved molecular dynamics of bacteriophage HK97 capsid maturation interpreted by electron cryo-microscopy and X-ray crystallography. J Struct Biol (2005) 1.24
New HEAT-like repeat motifs in proteins regulating proteasome structure and function. J Struct Biol (2004) 1.23
Mutations in interaction surfaces differentially impact E. coli Hfq association with small RNAs and their mRNA targets. J Mol Biol (2013) 1.23
Structure of the Blm10-20 S proteasome complex by cryo-electron microscopy. Insights into the mechanism of activation of mature yeast proteasomes. J Mol Biol (2006) 1.22
The axial channel of the 20S proteasome opens upon binding of the PA200 activator. J Mol Biol (2005) 1.22
Handedness of the herpes simplex virus capsid and procapsid. J Virol (2002) 1.21
Stability and shape of hepatitis B virus capsids in vacuo. Angew Chem Int Ed Engl (2008) 1.20
Crosslinking renders bacteriophage HK97 capsid maturation irreversible and effects an essential stabilization. EMBO J (2005) 1.20
A thermally induced phase transition in a viral capsid transforms the hexamers, leaving the pentamers unchanged. J Struct Biol (2006) 1.20
A free energy cascade with locks drives assembly and maturation of bacteriophage HK97 capsid. J Mol Biol (2006) 1.20
RSV capsid polymorphism correlates with polymerization efficiency and envelope glycoprotein content: implications that nucleation controls morphogenesis. J Mol Biol (2007) 1.19
The inner cavity of Escherichia coli DegP protein is not essential for molecular chaperone and proteolytic activity. J Bacteriol (2006) 1.19
Role of the PDZ domains in Escherichia coli DegP protein. J Bacteriol (2007) 1.19
The Escherichia coli MntR miniregulon includes genes encoding a small protein and an efflux pump required for manganese homeostasis. J Bacteriol (2011) 1.18
A second symmetry mismatch at the portal vertex of bacteriophage T7: 8-fold symmetry in the procapsid core. J Mol Biol (2003) 1.18
The turn of the screw: variations of the abundant beta-solenoid motif in passenger domains of Type V secretory proteins. J Struct Biol (2006) 1.18
Molecular mechanisms in bacteriophage T7 procapsid assembly, maturation, and DNA containment. Adv Protein Chem (2003) 1.16
Recombinant HA1 produced in E. coli forms functional oligomers and generates strain-specific SRID potency antibodies for pandemic influenza vaccines. Vaccine (2011) 1.14
Alternating translocation of protein substrates from both ends of ClpXP protease. EMBO J (2002) 1.14
Understanding ribosome assembly: the structure of in vivo assembled immature 30S subunits revealed by cryo-electron microscopy. RNA (2011) 1.14
Initial stages of V(D)J recombination: the organization of RAG1/2 and RSS DNA in the postcleavage complex. Mol Cell (2009) 1.13