Published in Circulation on January 22, 2002
KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging. Proc Natl Acad Sci U S A (2007) 3.30
Impact of 6-mo caloric restriction on myocardial ischemic tolerance: possible involvement of nitric oxide-dependent increase in nuclear Sirt1. Am J Physiol Heart Circ Physiol (2008) 1.36
Is impairment of ischaemic preconditioning by sulfonylurea drugs clinically important? Heart (2004) 1.09
Cardiolipin as an oxidative target in cardiac mitochondria in the aged rat. Biochim Biophys Acta (2008) 1.05
Endothelial-cardiomyocyte crosstalk enhances pharmacological cardioprotection. J Mol Cell Cardiol (2011) 0.96
Ischemic preconditioning: the role of mitochondria and aging. Exp Gerontol (2011) 0.93
Myocardial protection in man--from research concept to clinical practice. Heart Fail Rev (2007) 0.92
Impaired p38 MAPK/HSP27 signaling underlies aging-related failure in opioid-mediated cardioprotection. J Mol Cell Cardiol (2007) 0.91
Age-related attenuation of isoflurane preconditioning in human atrial cardiomyocytes: roles for mitochondrial respiration and sarcolemmal adenosine triphosphate-sensitive potassium channel activity. Anesthesiology (2008) 0.91
Mitochondria-targeted ROS scavenger improves post-ischemic recovery of cardiac function and attenuates mitochondrial abnormalities in aged rats. J Mol Cell Cardiol (2014) 0.90
Ischaemic tolerance in aged mouse myocardium: the role of adenosine and effects of A1 adenosine receptor overexpression. J Physiol (2003) 0.89
Mitochondrial Metabolism in Aging Heart. Circ Res (2016) 0.88
Autophagy, myocardial protection, and the metabolic syndrome. J Cardiovasc Pharmacol (2012) 0.88
Antiarrhythmic and anti-ischaemic effects of angina in patients with and without coronary collaterals. Heart (2002) 0.87
Clinical application of ischemic preconditioning in the elderly. Dose Response (2009) 0.87
Ischemic preconditioning in the younger and aged heart. Aging Dis (2011) 0.82
Age-related differences in cardiac ischemia-reperfusion injury: effects of estrogen deficiency. Pflugers Arch (2013) 0.81
Opposing effects of age and calorie restriction on molecular determinants of myocardial ischemic tolerance. Rejuvenation Res (2012) 0.81
Impact of hypoglycemic agents on myocardial ischemic preconditioning. World J Diabetes (2014) 0.79
Impact of caloric restriction on myocardial ischaemia/reperfusion injury and new therapeutic options to mimic its effects. Br J Pharmacol (2014) 0.79
Do we age because we have mitochondria? Protoplasma (2013) 0.77
Cardioprotection and ageing. Korean J Anesthesiol (2010) 0.77
Effects of nicorandil on the reduction of BNP levels in patients with chronic kidney disease. Clin Exp Nephrol (2011) 0.77
Age-related cardiovascular disease and the beneficial effects of calorie restriction. Heart Fail Rev (2012) 0.76
Ischaemic preconditioning and myocardial adaptation to serial intracoronary balloon inflation: cut from the same cloth? Heart (2004) 0.75
Role of Trimetazidine in Ischemic Preconditioning in Patients With Symptomatic Coronary Artery Disease. Medicine (Baltimore) (2015) 0.75
The Citrus Flavanone Naringenin Produces Cardioprotective Effects in Hearts from 1 Year Old Rat, through Activation of mitoBK Channels. Front Pharmacol (2017) 0.75
Cardiovascular KATP channels and advanced aging. Pathobiol Aging Age Relat Dis (2016) 0.75
Oral nicorandil recaptures the waned protection from preconditioning in vivo. Br J Pharmacol (2003) 0.75
Cardiac aging and insulin resistance: could insulin/insulin-like growth factor (IGF) signaling be used as a therapeutic target? Curr Pharm Des (2013) 0.75
Pro- and Antiarrhythmic Actions of Sulfonylureas: Mechanistic and Clinical Evidence. Trends Endocrinol Metab (2017) 0.75
Activation of ATP-sensitive potassium channels by nicorandil is preserved in aged vascular smooth muscle cells in rats. J Anesth (2013) 0.75
DNA methylation screening identifies driver epigenetic events of cancer cell survival. Cancer Cell (2012) 2.45
Plasma uric acid and the risk of type 2 diabetes in a Chinese community. Clin Chem (2007) 2.14
Habitual sleep duration and insomnia and the risk of cardiovascular events and all-cause death: report from a community-based cohort. Sleep (2010) 2.05
Impairment of myocardial protection in type 2 diabetic patients. J Clin Endocrinol Metab (2003) 2.04
Sympathetic nerve sprouting, electrical remodeling, and increased vulnerability to ventricular fibrillation in hypercholesterolemic rabbits. Circ Res (2003) 1.97
Homocysteine inhibits arterial endothelial cell growth through transcriptional downregulation of fibroblast growth factor-2 involving G protein and DNA methylation. Circ Res (2008) 1.78
Transcatheter closure of patent ductus arteriosus using Gianturco coils in adolescents and adults. Catheter Cardiovasc Interv (2002) 1.57
QTc dispersion as a prognostic factor in intracerebral hemorrhage. Am J Emerg Med (2004) 1.56
Major gene effects in systolic and diastolic blood pressure in families receiving a health examination in Taiwan. J Hypertens (2003) 1.50
Effects of simvastatin on cardiac neural and electrophysiologic remodeling in rabbits with hypercholesterolemia. Heart Rhythm (2008) 1.49
Elevated blood pressure, obesity, and hyperlipidemia. J Pediatr (2009) 1.48
Titanium dioxide nanoparticles induce emphysema-like lung injury in mice. FASEB J (2006) 1.46
Coronary stent strut avulsion in aorto-ostial in-stent restenosis: potential complication after cutting balloon angioplasty. Catheter Cardiovasc Interv (2002) 1.46
Export aspiration catheter thrombosuction before actual angioplasty in primary coronary intervention for acute myocardial infarction. Catheter Cardiovasc Interv (2002) 1.44
SARS in hospital emergency room. Emerg Infect Dis (2004) 1.44
LDLR and ApoB are major genetic causes of autosomal dominant hypercholesterolemia in a Taiwanese population. J Formos Med Assoc (2007) 1.43
Differential role of K(ATP) channels activated by conjugated estrogens in the regulation of myocardial and coronary protective effects. Circulation (2003) 1.42
Curcumin inhibits lung cancer cell invasion and metastasis through the tumor suppressor HLJ1. Cancer Res (2008) 1.29
Hyperuricemia as a risk factor on cardiovascular events in Taiwan: The Chin-Shan Community Cardiovascular Cohort Study. Atherosclerosis (2005) 1.29
Lung cancer and incidence of stroke: a population-based cohort study. Stroke (2011) 1.27
Relations of epicardial adipose tissue measured by multidetector computed tomography to components of the metabolic syndrome are region-specific and independent of anthropometric indexes and intraabdominal visceral fat. J Clin Endocrinol Metab (2008) 1.26
Zymogen activation, inhibition, and ectodomain shedding of matriptase. Front Biosci (2008) 1.24
Age- and gender-associated determinants of carotid intima-media thickness: a community-based study. J Atheroscler Thromb (2012) 1.19
Analysis of the outcome for patients experiencing myocardial infarction and cardiopulmonary resuscitation refractory to conventional therapies necessitating extracorporeal life support rescue. Crit Care Med (2006) 1.17
Prevalence, agreement and classification of various metabolic syndrome criteria among ethnic Chinese: a report on the hospital-based health diagnosis of the adult population. Atherosclerosis (2007) 1.15
Atrial fibrillation prevalence, incidence and risk of stroke and all-cause death among Chinese. Int J Cardiol (2008) 1.10
An intelligent telecardiology system using a wearable and wireless ECG to detect atrial fibrillation. IEEE Trans Inf Technol Biomed (2010) 1.09
Postresuscitation myocardial dysfunction: correlated factors and prognostic implications. Intensive Care Med (2006) 1.08
Carotid artery intima-media thickness, carotid plaque and coronary heart disease and stroke in Chinese. PLoS One (2008) 1.08
Anti-invasive gene expression profile of curcumin in lung adenocarcinoma based on a high throughput microarray analysis. Mol Pharmacol (2004) 1.06
Apolipoprotein B and non-high density lipoprotein cholesterol and the risk of coronary heart disease in Chinese. J Lipid Res (2007) 1.06
Metabolic syndrome as a risk factor for coronary heart disease and stroke: an 11-year prospective cohort in Taiwan community. Atherosclerosis (2006) 1.05
Red blood cell distribution width and risk of cardiovascular events and mortality in a community cohort in Taiwan. Am J Epidemiol (2009) 1.05
Association of epicardial adipose tissue with coronary atherosclerosis is region-specific and independent of conventional risk factors and intra-abdominal adiposity. Atherosclerosis (2010) 1.05
A prediction model for the risk of incident chronic kidney disease. Am J Med (2010) 1.05
Effects of rosiglitazone on endothelial function, C-reactive protein, and components of the metabolic syndrome in nondiabetic patients with the metabolic syndrome. Am J Cardiol (2004) 1.01
Comparing the efficacy and safety of atorvastatin and simvastatin in Asians with elevated low-density lipoprotein-cholesterol--a multinational, multicenter, double-blind study. J Formos Med Assoc (2002) 1.00
Association of pravastatin and left ventricular mass in hypercholesterolemic patients: role of 8-iso-prostaglandin f2alpha formation. J Cardiovasc Pharmacol (2002) 1.00
Cyclosporine A regulate oxidative stress-induced apoptosis in cardiomyocytes: mechanisms via ROS generation, iNOS and Hsp70. Br J Pharmacol (2002) 0.99
Efficacy of fenofibrate and simvastatin on endothelial function and inflammatory markers in patients with combined hyperlipidemia: relations with baseline lipid profiles. Atherosclerosis (2003) 0.98
Urinary sodium and potassium excretion and risk of hypertension in Chinese: report from a community-based cohort study in Taiwan. J Hypertens (2008) 0.97
Effects of menopause on intraindividual changes in serum lipids, blood pressure, and body weight--the Chin-Shan Community Cardiovascular Cohort study. Atherosclerosis (2002) 0.96
A randomised study comparing the efficacy and safety of rosuvastatin with atorvastatin for achieving lipid goals in clinical practice in Asian patients at high risk of cardiovascular disease (DISCOVERY-Asia study). Curr Med Res Opin (2007) 0.95
Differential effects of sarcolemmal and mitochondrial K(ATP) channels activated by 17 beta-estradiol on reperfusion arrhythmias and infarct sizes in canine hearts. J Pharmacol Exp Ther (2002) 0.95
Genetic association study of APOA1/C3/A4/A5 gene cluster and haplotypes on triglyceride and HDL cholesterol in a community-based population. Clin Chim Acta (2007) 0.95
Constructing the prediction model for the risk of stroke in a Chinese population: report from a cohort study in Taiwan. Stroke (2010) 0.95
Electronegative LDL impairs vascular endothelial cell integrity in diabetes by disrupting fibroblast growth factor 2 (FGF2) autoregulation. Diabetes (2007) 0.95
Effect of pravastatin on proteinuria in patients with well-controlled hypertension. Hypertension (2002) 0.95
Chronic hepatitis B virus infection and dyslipidemia. J Formos Med Assoc (2004) 0.94
Usefulness of ST-segment elevation in lead aVR during tachycardia for determining the mechanism of narrow QRS complex tachycardia. Am J Cardiol (2003) 0.93
Twenty-four-hour ambulatory blood pressure and duration of hypertension as major determinants for intima-media thickness and atherosclerosis of carotid arteries. Atherosclerosis (2005) 0.93
Dyslipidemia is associated with ventricular tachyarrhythmia in patients with acute ST-segment elevation myocardial infarction. J Formos Med Assoc (2006) 0.92
Lipoprotein(a) and cardiovascular disease in ethnic Chinese: the Chin-Shan Community Cardiovascular Cohort Study. Clin Chem (2007) 0.92
Use of serum homocysteine to predict stroke, coronary heart disease and death in ethnic Chinese. 12-year prospective cohort study. Circ J (2009) 0.91
Increased cardiomyocyte apoptosis following ischemia and reperfusion in diet-induced hypercholesterolemia: relation to Bcl-2 and Bax proteins and caspase-3 activity. Lipids (2002) 0.91
Impact of heart failure and left ventricular function on long-term survival--report of a community-based cohort study in Taiwan. Eur J Heart Fail (2007) 0.91
More hemorrhagic and severe events cause higher hospitalization care cost for childhood stroke in Taiwan. J Pediatr (2007) 0.90
Aspirin protects human coronary artery endothelial cells against atherogenic electronegative LDL via an epigenetic mechanism: a novel cytoprotective role of aspirin in acute myocardial infarction. Cardiovasc Res (2013) 0.90
Xanthoma striatum palmare in a patient with primary biliary cirrhosis and hypercholesterolemia. J Gastroenterol Hepatol (2005) 0.89
Effect of hypercholesterolemia on myocardial function in New Zealand white rabbits. J Biomed Sci (2004) 0.89
Consistency of genetic inheritance mode and heritability patterns of triglyceride vs. high density lipoprotein cholesterol ratio in two Taiwanese family samples. BMC Genet (2003) 0.89
Left ventricular mass and risk of cardiovascular events and all-cause death among ethnic Chinese--the Chin-Shan Community Cardiovascular Cohort study. Int J Cardiol (2010) 0.89
Factors influencing the outcomes after in-hospital resuscitation in Taiwan. Resuscitation (2002) 0.88
Heritability and major gene effects on left ventricular mass in the Chinese population: a family study. BMC Cardiovasc Disord (2006) 0.87
Left atrial dimension and risk of stroke in women without atrial fibrillation: the Chin-Shan Community Cardiovascular Cohort study. Echocardiography (2011) 0.87
Lipoprotein-X reduces LDL atherogenicity in primary biliary cirrhosis by preventing LDL oxidation. J Lipid Res (2004) 0.87
Comparative assessment of the HAS-BLED score with other published bleeding risk scoring schemes, for intracranial haemorrhage risk in a non-atrial fibrillation population: the Chin-Shan Community Cohort Study. Int J Cardiol (2013) 0.86
Comparative assessment of published atrial fibrillation stroke risk stratification schemes for predicting stroke, in a non-atrial fibrillation population: the Chin-Shan Community Cohort Study. Int J Cardiol (2012) 0.86
Adjunctive 17beta-estradiol administration reduces infarct size by altered expression of canine myocardial connexin43 protein. Cardiovasc Res (2004) 0.86
Incidence of hypertension and risk of cardiovascular events among ethnic Chinese: report from a community-based cohort study in Taiwan. J Hypertens (2007) 0.86
Renal function and metabolic syndrome components on cardiovascular and all-cause mortality. Atherosclerosis (2007) 0.86
Constructing a point-based prediction model for the risk of coronary artery disease in a Chinese community: a report from a cohort study in Taiwan. Int J Cardiol (2012) 0.86
Effect of ischaemic preconditioning on regional release of inflammatory markers. Clin Sci (Lond) (2005) 0.85
Downregulated myocardial connexin 43 and suppressed contractility in rabbits subjected to a cholesterol-enriched diet. Lab Invest (2005) 0.85
Global analysis of differentially expressed genes in early gestational decidua and chorionic villi using a 9600 human cDNA microarray. Mol Hum Reprod (2002) 0.85
Apolipoprotein A-I and B and stroke events in a community-based cohort in Taiwan: report of the Chin-Shan Community Cardiovascular Study. Stroke (2002) 0.85
Effect of simvastatin on left ventricular mass in hypercholesterolemic rabbits. Am J Physiol Heart Circ Physiol (2004) 0.85
Ascorbate supplement reduces oxidative stress in dyslipidemic patients undergoing apheresis. Arterioscler Thromb Vasc Biol (2004) 0.84
Attenuation of increased myocardial ischaemia-reperfusion injury conferred by hypercholesterolaemia through pharmacological inhibition of the caspase-1 cascade. Br J Pharmacol (2003) 0.84
Relative importance of atherosclerotic risk factors for coronary heart disease in Taiwan. Eur J Cardiovasc Prev Rehabil (2005) 0.83
Electronegative low-density lipoprotein induces cardiomyocyte apoptosis indirectly through endothelial cell-released chemokines. Apoptosis (2012) 0.83
Identification of the HDL-ApoCIII to VLDL-ApoCIII ratio as a predictor of coronary artery disease in the general population: the Chin-Shan Community Cardiovascular Cohort (CCCC) study in Taiwan. Lipids Health Dis (2012) 0.83
Effects of sulfonylureas on left ventricular mass in type 2 diabetic patients. Am J Physiol Heart Circ Physiol (2006) 0.83
Quercetin significantly decreased cyclosporin oral bioavailability in pigs and rats. Life Sci (2002) 0.83
Usefulness of paradoxical systolic blood pressure increase after exercise as a predictor of cardiovascular mortality. Am J Cardiol (2008) 0.83
High-density lipoprotein antagonizes oxidized low-density lipoprotein by suppressing oxygen free-radical formation and preserving nitric oxide bioactivity. Atherosclerosis (2005) 0.83
Two-year change in body mass index and subsequent risk of hypertension among men and women in a Taiwan community. J Hypertens (2009) 0.83
Fasting and postchallenge hyperglycemia and risk of cardiovascular disease in Chinese: the Chin-Shan Community Cardiovascular Cohort study. Am Heart J (2008) 0.83
Add-on and withdrawal effect of pravastatin on proteinuria in hypertensive patients treated with AT receptor blockers. Kidney Int (2005) 0.82
Intima-media thickness of lower-limb arteries associated with fasting and post-challenge plasma glucose levels. J Atheroscler Thromb (2009) 0.82
Effects of pravastatin on cardiomyocyte hypertrophy and ventricular vulnerability in normolipidemic rats after myocardial infarction. J Mol Cell Cardiol (2003) 0.82
Metabolic syndrome and C-reactive protein in stroke prediction: a prospective study in Taiwan. Metabolism (2009) 0.82
Major gene effects on apolipoprotein B concentrations in families of adolescents--results from a community-based study in Taiwan. Clin Chim Acta (2005) 0.82