Cyclosporine A regulate oxidative stress-induced apoptosis in cardiomyocytes: mechanisms via ROS generation, iNOS and Hsp70.

PubWeight™: 0.99‹?› | Rank: Top 15%

🔗 View Article (PMC 1573548)

Published in Br J Pharmacol on November 01, 2002

Authors

Huei-Wen Chen1, Chiang-Ting Chien, Sung-Liang Yu, Yuan-Teh Lee, Wen-Jone Chen

Author Affiliations

1: Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan.

Articles citing this

A novel protective effect of erythropoietin in the infarcted heart. J Clin Invest (2003) 2.32

Protection of peroxiredoxin II on oxidative stress-induced cardiomyocyte death and apoptosis. Basic Res Cardiol (2008) 0.98

Role of oxidative stress and apoptosis in the placental pathology of Plasmodium berghei infected mice. PLoS One (2012) 0.88

Clonogenicity of human leukemic cells protected from cell-lethal agents by heat shock protein 70. Cell Stress Chaperones (2005) 0.86

Provinol prevents CsA-induced nephrotoxicity by reducing reactive oxygen species, iNOS, and NF-kB expression. J Histochem Cytochem (2005) 0.84

Loss of proteostatic control as a substrate for atrial fibrillation: a novel target for upstream therapy by heat shock proteins. Front Physiol (2012) 0.83

Reversing multidrug resistance in hepatocellular carcinoma cells by inhibiting extracellular signal-regulated kinase/mitogen-activated protein kinase signaling pathway activity. Oncol Lett (2014) 0.82

Tanshinone IIA and Cryptotanshinone Prevent Mitochondrial Dysfunction in Hypoxia-Induced H9c2 Cells: Association to Mitochondrial ROS, Intracellular Nitric Oxide, and Calcium Levels. Evid Based Complement Alternat Med (2013) 0.81

Ischemia-induced apoptosis of intestinal epithelial cells correlates with altered integrin distribution and disassembly of F-actin triggered by calcium overload. J Biomed Biotechnol (2012) 0.79

Protective effects of peroxiredoxin on hydrogen peroxide induced oxidative stress and apoptosis in cardiomyocytes. Korean Circ J (2012) 0.79

Cyclosporin A promotes proliferating cell nuclear antigen expression and migration of human cytotrophoblast cells via the mitgen-activated protein kinase-3/1-mediated nuclear factor-κB signaling pathways. Int J Clin Exp Pathol (2013) 0.77

Overexpression of Brg1 Alleviates Hepatic Ischemia/Reperfusion-Induced Acute Lung Injury through Antioxidative Stress Effects. Oxid Med Cell Longev (2017) 0.75

Dose and timing of injections for effective cyclosporine A pretreatment before renal ischemia reperfusion in mice. PLoS One (2017) 0.75

Articles cited by this

Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods (1983) 114.35

Mitochondria and apoptosis. Science (1998) 23.41

Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J Immunol Methods (1986) 12.51

Requirement for generation of H2O2 for platelet-derived growth factor signal transduction. Science (1995) 8.17

The mechanism of action of cyclosporin A and FK506. Immunol Today (1992) 7.57

Cyclosporine. N Engl J Med (1989) 5.67

Detection and imaging of nitric oxide with novel fluorescent indicators: diaminofluoresceins. Anal Chem (1998) 4.77

Mitochondrial control of apoptosis. Immunol Today (1997) 4.74

Inhibition of Ca2(+)-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adenine nucleotide translocase. Biochem J (1990) 2.84

Cardioprotective function of inducible nitric oxide synthase and role of nitric oxide in myocardial ischemia and preconditioning: an overview of a decade of research. J Mol Cell Cardiol (2001) 2.82

Properties of a clonal muscle cell line from rat heart. Exp Cell Res (1976) 2.71

Protection by Cyclosporin A of ischemia/reperfusion-induced damage in isolated rat hearts. J Mol Cell Cardiol (1993) 2.67

Hydrogen peroxide- and peroxynitrite-induced mitochondrial DNA damage and dysfunction in vascular endothelial and smooth muscle cells. Circ Res (2000) 2.62

Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss. J Biol Chem (1998) 2.51

Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytes. J Biol Chem (1998) 2.44

Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes. J Biol Chem (1998) 2.37

Evaluation of fluorescent dyes for the detection of mitochondrial membrane potential changes in cultured cardiomyocytes. Cardiovasc Res (2000) 2.22

Regulation of bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes: association with changes in mitochondrial membrane potential. Circ Res (1999) 2.18

Oxygen radicals released during ischemic preconditioning contribute to cardioprotection in the rabbit myocardium. J Mol Cell Cardiol (1997) 2.15

Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reoxygenation. Circ Res (2000) 2.14

Apoptosis: basic mechanisms and implications for cardiovascular disease. Circ Res (1998) 2.01

Medical and cellular implications of stunning, hibernation, and preconditioning: an NHLBI workshop. Circulation (1998) 1.96

Cytokine-mediated apoptosis in cardiac myocytes: the role of inducible nitric oxide synthase induction and peroxynitrite generation. Circ Res (1999) 1.81

Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis. Circulation (1999) 1.74

Hypoxia-activated apoptosis of cardiac myocytes requires reoxygenation or a pH shift and is independent of p53. J Clin Invest (1999) 1.58

Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis. FEBS Lett (1996) 1.58

Bimoclomol: a nontoxic, hydroxylamine derivative with stress protein-inducing activity and cytoprotective effects. Nat Med (1997) 1.50

Isoform-selective activation of protein kinase C by nitric oxide in the heart of conscious rabbits: a signaling mechanism for both nitric oxide-induced and ischemia-induced preconditioning. Circ Res (1999) 1.48

Does cyclosporin A generate free radicals? Trends Pharmacol Sci (2000) 1.48

Ischaemic preconditioning of the vasculature: an overlooked phenomenon for protecting the heart? Trends Pharmacol Sci (2000) 1.48

Mechanisms of cell death in hypoxia/reoxygenation injury. Oncogene (1998) 1.29

BCL-2 expression or antioxidants prevent hyperglycemia-induced formation of intracellular advanced glycation endproducts in bovine endothelial cells. J Clin Invest (1996) 1.28

Cyclosporin A increases hypoxia and free radical production in rat kidneys: prevention by dietary glycine. Am J Physiol (1998) 1.24

Oxidant mechanisms in toxic acute renal failure. Am J Kidney Dis (1997) 1.20

Cyclosporin A inhibits apoptosis of human endothelial cells by preventing release of cytochrome C from mitochondria. Circulation (1998) 1.11

Cyclosporine A-induced oxidative stress in rat hepatocytes. J Pharmacol Exp Ther (1997) 1.08

Dinitrophenol, cyclosporin A, and trimetazidine modulate preconditioning in the isolated rat heart: support for a mitochondrial role in cardioprotection. Cardiovasc Res (2000) 1.07

Supravital exposure to propidium iodide identifies apoptotic cells in the absence of nucleosomal DNA fragmentation. Cytometry (1996) 1.07

Inducible nitric oxide synthase mediates delayed myocardial protection induced by activation of adenosine A(1) receptors: evidence from gene-knockout mice. Circulation (2000) 1.02

Reduction in myocardial apoptosis associated with overexpression of heat shock protein 70. Basic Res Cardiol (2000) 1.01

Cyclosporine A limits myocardial infarct size even when administered after onset of ischemia. Cardiovasc Res (1998) 1.01

Role of reactive oxygen species in the signalling cascade of cyclosporine A-mediated up-regulation of eNOS in vascular endothelial cells. Br J Pharmacol (1998) 1.01

Photoactivation and calcium sensitivity of the fluorescent NO indicator 4,5-diaminofluorescein (DAF-2): implications for cellular NO imaging. FEBS Lett (2001) 0.96

Oxygen free radical signaling in ischemic preconditioning. Ann N Y Acad Sci (1999) 0.95

Hypoxia and hypoxia/reoxygenation activate Raf-1, mitogen-activated protein kinase kinase, mitogen-activated protein kinases, and S6 kinase in cultured rat cardiac myocytes. Circ Res (1996) 0.93

Reactive oxygen species function as second messenger during ischemic preconditioning of heart. Mol Cell Biochem (1999) 0.93

Ischemic preconditioning in isolated cells. Circ Res (2000) 0.93

Mitochondria in muscle cell death. Ital J Neurol Sci (1999) 0.89

Effect of cyclosporin A and its vehicle on cardiac and skeletal muscle mitochondria: relationship to efficacy of the respiratory chain. Br J Pharmacol (2001) 0.87

Cyclosporine induces different responses in human epithelial, endothelial and fibroblast cell cultures. Kidney Int (2000) 0.87

Cellular and molecular dissection of reperfusion injury: ROS within and without. Circ Res (2000) 0.87

Dietary glycine and renal denervation prevents cyclosporin A-induced hydroxyl radical production in rat kidney. Mol Pharmacol (1999) 0.86

Cyclosporin A induces an atypical heat shock response. Biochem Biophys Res Commun (2000) 0.84

Nitric oxide triggers programmed cell death (apoptosis) of adult rat ventricular myocytes in culture. Am J Physiol (1999) 0.83

Effect of alisol B acetate, a plant triterpene, on apoptosis in vascular smooth muscle cells and lymphocytes. Eur J Pharmacol (2001) 0.83

Cardioprotection by cyclosporine A in experimental ischemia and reperfusion--evidence for a nitric oxide-dependent mechanism mediated by endothelin. J Mol Cell Cardiol (1997) 0.83

Myocardial toxicity of cyclosporin A: inhibition of calcium ATPase and nitric oxide synthase activities and attenuation by fructose-1,6-diphosphate in vitro. Res Commun Mol Pathol Pharmacol (1995) 0.81

Apoptosis: rekindling the mitochondrial fire. Circ Res (1999) 0.80

Myocardial adaptation to ischaemia--the preconditioning phenomenon. Int J Cardiol (1999) 0.80

Nitrosative stress by cyclosporin A in the endothelium: studies with the NO-sensitive probe diaminofluorescein-2/diacetate using flow cytometry. Nephrol Dial Transplant (2001) 0.80

Separation of pigmented and albino melanocytes and the concomitant evaluation of endogenous peroxide content using flow cytometry. Cytometry (1989) 0.80

Cyclosporin-induced endothelial dysfunction and hypertension: are nitric oxide system abnormality and oxidative stress involved? Transpl Int (2000) 0.78

Superoxide limits cyclosporine-A-induced formation of peroxynitrite in endothelial cells(2). Free Radic Biol Med (2002) 0.77

Heat shock proteins and ischemic injury to the myocardium. Circulation (1997) 0.77

Effects of bimoclomol, the novel heat shock protein coinducer, in dog ventricular myocardium. Life Sci (2000) 0.76

Changes in the cardiovascular nitric oxide pathway in cyclosporin-A treated rats. Drug Chem Toxicol (1998) 0.76

Sublethal heat shock and cyclosporine exposure produce tolerance against subsequent cyclosporine toxicity. Am J Physiol (1996) 0.76

Articles by these authors

A five-gene signature and clinical outcome in non-small-cell lung cancer. N Engl J Med (2007) 10.47

Cardiopulmonary resuscitation with assisted extracorporeal life-support versus conventional cardiopulmonary resuscitation in adults with in-hospital cardiac arrest: an observational study and propensity analysis. Lancet (2008) 6.30

Simple aspiration and drainage and intrapleural minocycline pleurodesis versus simple aspiration and drainage for the initial treatment of primary spontaneous pneumothorax: an open-label, parallel-group, prospective, randomised, controlled trial. Lancet (2013) 3.29

Pretreatment epidermal growth factor receptor (EGFR) T790M mutation predicts shorter EGFR tyrosine kinase inhibitor response duration in patients with non-small-cell lung cancer. J Clin Oncol (2012) 2.91

Plasma uric acid and the risk of type 2 diabetes in a Chinese community. Clin Chem (2007) 2.14

Free radicals mediate postshock contractile impairment in cardiomyocytes. Crit Care Med (2008) 2.09

Plasma prohepcidin positively correlates with hematocrit in chronic hemodialysis patients. Blood Purif (2006) 2.07

Habitual sleep duration and insomnia and the risk of cardiovascular events and all-cause death: report from a community-based cohort. Sleep (2010) 2.05

Occult Staphylococcus aureus bacteremia in adult emergency department patients: rare but important. Clin Infect Dis (2012) 1.97

Sympathetic nerve sprouting, electrical remodeling, and increased vulnerability to ventricular fibrillation in hypercholesterolemic rabbits. Circ Res (2003) 1.97

Slug confers resistance to the epidermal growth factor receptor tyrosine kinase inhibitor. Am J Respir Crit Care Med (2010) 1.95

Enterovirus-induced miR-141 contributes to shutoff of host protein translation by targeting the translation initiation factor eIF4E. Cell Host Microbe (2011) 1.88

Homocysteine inhibits arterial endothelial cell growth through transcriptional downregulation of fibroblast growth factor-2 involving G protein and DNA methylation. Circ Res (2008) 1.78

Delayed fluid resuscitation in hemorrhagic shock induces proinflammatory cytokine response. Ann Emerg Med (2006) 1.62

Evaluating the quality of prehospital cardiopulmonary resuscitation by reviewing automated external defibrillator records and survival for out-of-hospital witnessed arrests. Resuscitation (2005) 1.61

Spontaneous urinary extravasation: an overlooked cause of acute abdomen in ED. Am J Emerg Med (2006) 1.61

MicroRNA-18a prevents estrogen receptor-alpha expression, promoting proliferation of hepatocellular carcinoma cells. Gastroenterology (2008) 1.60

Dynamic plasma EGFR mutation status as a predictor of EGFR-TKI efficacy in patients with EGFR-mutant lung adenocarcinoma. J Thorac Oncol (2015) 1.59

Transcatheter closure of patent ductus arteriosus using Gianturco coils in adolescents and adults. Catheter Cardiovasc Interv (2002) 1.57

QTc dispersion as a prognostic factor in intracerebral hemorrhage. Am J Emerg Med (2004) 1.56

A cost-effectiveness analysis of treatment strategies for acute uncomplicated pyelonephritis in women. Acad Emerg Med (2003) 1.56

Methylene 3, 4 dioxymethamphetamine-induced acute myocardial infarction. Ann Emerg Med (2003) 1.54

Major gene effects in systolic and diastolic blood pressure in families receiving a health examination in Taiwan. J Hypertens (2003) 1.50

Effects of simvastatin on cardiac neural and electrophysiologic remodeling in rabbits with hypercholesterolemia. Heart Rhythm (2008) 1.49

MicroRNA-519c suppresses hypoxia-inducible factor-1alpha expression and tumor angiogenesis. Cancer Res (2010) 1.49

The effect of hydrocortisone on the outcome of out-of-hospital cardiac arrest patients: a pilot study. Am J Emerg Med (2007) 1.48

Salvage for unsuccessful aspiration of primary pneumothorax: thoracoscopic surgery or chest tube drainage? Ann Thorac Surg (2008) 1.48

Elevated blood pressure, obesity, and hyperlipidemia. J Pediatr (2009) 1.48

Vitreous levels of reactive oxygen species in proliferative diabetic retinopathy. Ophthalmology (2008) 1.47

MicroRNA expression aberration as potential peripheral blood biomarkers for schizophrenia. PLoS One (2011) 1.47

Titanium dioxide nanoparticles induce emphysema-like lung injury in mice. FASEB J (2006) 1.46

Coronary stent strut avulsion in aorto-ostial in-stent restenosis: potential complication after cutting balloon angioplasty. Catheter Cardiovasc Interv (2002) 1.46

Export aspiration catheter thrombosuction before actual angioplasty in primary coronary intervention for acute myocardial infarction. Catheter Cardiovasc Interv (2002) 1.44

SARS in hospital emergency room. Emerg Infect Dis (2004) 1.44

Individual effect of components of defibrillation waveform on the contractile function and intracellular calcium dynamics of cardiomyocytes. Crit Care Med (2009) 1.43

LDLR and ApoB are major genetic causes of autosomal dominant hypercholesterolemia in a Taiwanese population. J Formos Med Assoc (2007) 1.43

Safety and six-month durability of angioplasty for isolated penile artery stenoses in patients with erectile dysfunction: a first-in-man study. EuroIntervention (2014) 1.42

An unusual cause of acute pulmonary embolism. Int J Cardiol (2010) 1.39

Active compression-decompression resuscitation and impedance threshold device for out-of-hospital cardiac arrest: a systematic review and metaanalysis of randomized controlled trials. Crit Care Med (2015) 1.38

Pentoxifylline attenuated the renal disease progression in rats with remnant kidney. J Am Soc Nephrol (2002) 1.36

Selective use of ultrasonography for the detection of pneumoperitoneum. Acad Emerg Med (2002) 1.36

Tracheal rupture complicating emergent endotracheal intubation. Am J Emerg Med (2004) 1.35

Claudin-1 is a metastasis suppressor and correlates with clinical outcome in lung adenocarcinoma. Am J Respir Crit Care Med (2008) 1.29

Curcumin inhibits lung cancer cell invasion and metastasis through the tumor suppressor HLJ1. Cancer Res (2008) 1.29

Hyperuricemia as a risk factor on cardiovascular events in Taiwan: The Chin-Shan Community Cardiovascular Cohort Study. Atherosclerosis (2005) 1.29

Urban air pollution and emergency admissions for cerebrovascular diseases in Taipei, Taiwan. Eur Heart J (2006) 1.28

Lung cancer and incidence of stroke: a population-based cohort study. Stroke (2011) 1.27

Relations of epicardial adipose tissue measured by multidetector computed tomography to components of the metabolic syndrome are region-specific and independent of anthropometric indexes and intraabdominal visceral fat. J Clin Endocrinol Metab (2008) 1.26

Galectin-1 promotes lung cancer progression and chemoresistance by upregulating p38 MAPK, ERK, and cyclooxygenase-2. Clin Cancer Res (2012) 1.24

Loss of preconditioning by attenuated activation of myocardial ATP-sensitive potassium channels in elderly patients undergoing coronary angioplasty. Circulation (2002) 1.22

A four-gene signature from NCI-60 cell line for survival prediction in non-small cell lung cancer. Clin Cancer Res (2009) 1.20

Age- and gender-associated determinants of carotid intima-media thickness: a community-based study. J Atheroscler Thromb (2012) 1.19

Target identification of microRNAs expressed highly in human embryonic stem cells. J Cell Biochem (2009) 1.19

How much would you be willing to pay for preventing a new dangerous infectious disease: a willingness-to-pay study in medical personnel working in the emergency department. Am J Infect Control (2007) 1.19

A web-based Utstein style registry system of in-hospital cardiopulmonary resuscitation in Taiwan. Resuscitation (2006) 1.18

Overexpression of placenta growth factor contributes to the pathogenesis of pulmonary emphysema. Am J Respir Crit Care Med (2003) 1.16

S3 detection as a diagnostic and prognostic aid in emergency department patients with acute dyspnea. Ann Emerg Med (2009) 1.15

Prevalence, agreement and classification of various metabolic syndrome criteria among ethnic Chinese: a report on the hospital-based health diagnosis of the adult population. Atherosclerosis (2007) 1.15

Increasing cardiopulmonary emergency visits by long-range transported Asian dust storms in Taiwan. Environ Res (2007) 1.14

Ultrasonographic screening of clinically-suspected necrotizing fasciitis. Acad Emerg Med (2002) 1.11

Atrial fibrillation prevalence, incidence and risk of stroke and all-cause death among Chinese. Int J Cardiol (2008) 1.10

Comparative effects of flavonoids on oxidant scavenging and ischemia-reperfusion injury in cardiomyocytes. Eur J Pharmacol (2007) 1.10

Cardiac troponin I levels are a risk factor for mortality and multiple organ failure in noncardiac critically ill patients and have an additive effect to the APACHE II score in outcome prediction. Shock (2004) 1.10

Ischemic conditioning by short periods of reperfusion attenuates renal ischemia/reperfusion induced apoptosis and autophagy in the rat. J Biomed Sci (2009) 1.09

An intelligent telecardiology system using a wearable and wireless ECG to detect atrial fibrillation. IEEE Trans Inf Technol Biomed (2010) 1.09

Postresuscitation myocardial dysfunction: correlated factors and prognostic implications. Intensive Care Med (2006) 1.08

Carotid artery intima-media thickness, carotid plaque and coronary heart disease and stroke in Chinese. PLoS One (2008) 1.08

Induction of DNA damage-inducible gene GADD45beta contributes to sorafenib-induced apoptosis in hepatocellular carcinoma cells. Cancer Res (2010) 1.07

Sorafenib relieves cell-intrinsic and cell-extrinsic inhibitions of effector T cells in tumor microenvironment to augment antitumor immunity. Int J Cancer (2013) 1.06

Prognostic value of mortality in emergency department sepsis score, procalcitonin, and C-reactive protein in patients with sepsis at the emergency department. Shock (2008) 1.06

Apolipoprotein B and non-high density lipoprotein cholesterol and the risk of coronary heart disease in Chinese. J Lipid Res (2007) 1.06

Anti-invasive gene expression profile of curcumin in lung adenocarcinoma based on a high throughput microarray analysis. Mol Pharmacol (2004) 1.06

Metabolic syndrome as a risk factor for coronary heart disease and stroke: an 11-year prospective cohort in Taiwan community. Atherosclerosis (2006) 1.05

Association of epicardial adipose tissue with coronary atherosclerosis is region-specific and independent of conventional risk factors and intra-abdominal adiposity. Atherosclerosis (2010) 1.05

Red blood cell distribution width and risk of cardiovascular events and mortality in a community cohort in Taiwan. Am J Epidemiol (2009) 1.05

A prediction model for the risk of incident chronic kidney disease. Am J Med (2010) 1.05

Hypoxic preconditioning reinforces HIF-alpha-dependent HSP70 signaling to reduce ischemic renal failure-induced renal tubular apoptosis and autophagy. Life Sci (2009) 1.05

Repetitive hypoxic preconditioning attenuates renal ischemia/reperfusion induced oxidative injury via upregulating HIF-1 alpha-dependent bcl-2 signaling. Transplantation (2009) 1.04

Unilateral ureteral obstruction evokes renal tubular apoptosis via the enhanced oxidative stress and endoplasmic reticulum stress in the rat. Neurourol Urodyn (2011) 1.03

miRNA-34b as a tumor suppressor in estrogen-dependent growth of breast cancer cells. Breast Cancer Res (2011) 1.03

Chronic green tea extract supplementation reduces hemodialysis-enhanced production of hydrogen peroxide and hypochlorous acid, atherosclerotic factors, and proinflammatory cytokines. Am J Clin Nutr (2007) 1.03

A novel function of YWHAZ/β-catenin axis in promoting epithelial-mesenchymal transition and lung cancer metastasis. Mol Cancer Res (2012) 1.02

Utilization of and direct expenditure for emergency medical care in Taiwan: a population-based descriptive study. J Epidemiol (2009) 1.02

Effects of rosiglitazone on endothelial function, C-reactive protein, and components of the metabolic syndrome in nondiabetic patients with the metabolic syndrome. Am J Cardiol (2004) 1.01

Oxidative stress during 1-lung ventilation. J Thorac Cardiovasc Surg (2006) 1.01

Outcomes from out-of-hospital cardiac arrest in Metropolitan Taipei: does an advanced life support service make a difference? Resuscitation (2007) 1.01

IKZF1 deletions predict a poor prognosis in children with B-cell progenitor acute lymphoblastic leukemia: a multicenter analysis in Taiwan. Cancer Sci (2011) 1.00

Comparing the efficacy and safety of atorvastatin and simvastatin in Asians with elevated low-density lipoprotein-cholesterol--a multinational, multicenter, double-blind study. J Formos Med Assoc (2002) 1.00

A new method to estimate the amplitude spectrum analysis of ventricular fibrillation during cardiopulmonary resuscitation. Resuscitation (2013) 0.99