Published in Proteins on February 01, 2002
Designed oligomers of cyanovirin-N show enhanced HIV neutralization. Proc Natl Acad Sci U S A (2011) 0.86
Rational and computational design of stabilized variants of cyanovirin-N that retain affinity and specificity for glycan ligands. Biochemistry (2011) 0.79
A Designed "Nested" Dimer of Cyanovirin-N Increases Antiviral Activity. Viruses (2016) 0.75
Genome sequence of the ultrasmall unicellular red alga Cyanidioschyzon merolae 10D. Nature (2004) 5.08
A common sense approach to peak picking in two-, three-, and four-dimensional spectra using automatic computer analysis of contour diagrams. 1991. J Magn Reson (2011) 3.69
Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics. Nature (2013) 2.98
Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism. Nat Struct Mol Biol (2009) 2.77
Males evolved from the dominant isogametic mating type. Curr Biol (2006) 2.69
Characterizing the unfolded states of proteins using single-molecule FRET spectroscopy and molecular simulations. Proc Natl Acad Sci U S A (2007) 2.65
Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo. Nat Med (2004) 2.51
Deaminase-independent inhibition of HIV-1 reverse transcription by APOBEC3G. Nucleic Acids Res (2007) 2.49
Structural convergence between Cryo-EM and NMR reveals intersubunit interactions critical for HIV-1 capsid function. Cell (2009) 2.32
Experimental determination of upper bound for transition path times in protein folding from single-molecule photon-by-photon trajectories. Proc Natl Acad Sci U S A (2009) 2.29
Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models. AIDS Res Hum Retroviruses (2004) 2.22
Oligosaccharide and glycoprotein microarrays as tools in HIV glycobiology; glycan-dependent gp120/protein interactions. Chem Biol (2004) 2.22
High resolution crystal structures of HIV-1 protease with a potent non-peptide inhibitor (UIC-94017) active against multi-drug-resistant clinical strains. J Mol Biol (2004) 2.21
Rapid structural fluctuations of the free HIV protease flaps in solution: relationship to crystal structures and comparison with predictions of dynamics calculations. Protein Sci (2002) 2.17
Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding. Structure (2006) 2.16
NMR study of the tetrameric KcsA potassium channel in detergent micelles. Protein Sci (2006) 2.07
Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp. J Biol Chem (2004) 2.07
Single-molecule fluorescence experiments determine protein folding transition path times. Science (2012) 2.00
Male fertility of malaria parasites is determined by GCS1, a plant-type reproduction factor. Curr Biol (2008) 1.96
Cyanovirin-N gel as a topical microbicide prevents rectal transmission of SHIV89.6P in macaques. AIDS Res Hum Retroviruses (2003) 1.92
Structure and dynamics of KH domains from FBP bound to single-stranded DNA. Nature (2002) 1.89
HIV/simian immunodeficiency virus (SIV) accessory virulence factor Vpx loads the host cell restriction factor SAMHD1 onto the E3 ubiquitin ligase complex CRL4DCAF1. J Biol Chem (2012) 1.86
Anatomic study of the superior right colic vein: its relevance to pancreatic and colonic surgery. Am J Surg (2006) 1.78
Tetramerization of SAMHD1 is required for biological activity and inhibition of HIV infection. J Biol Chem (2013) 1.76
The complete influenza hemagglutinin fusion domain adopts a tight helical hairpin arrangement at the lipid:water interface. Proc Natl Acad Sci U S A (2010) 1.75
Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides. J Biol Chem (2002) 1.71
Visualizing transient events in amino-terminal autoprocessing of HIV-1 protease. Nature (2008) 1.69
A plant-specific dynamin-related protein forms a ring at the chloroplast division site. Plant Cell (2003) 1.69
Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114. J Mol Biol (2006) 1.66
Insights into equilibrium dynamics of proteins from comparison of NMR and X-ray data with computational predictions. Structure (2007) 1.66
Dimerization of the class A G protein-coupled neurotensin receptor NTS1 alters G protein interaction. Proc Natl Acad Sci U S A (2007) 1.66
Structural basis of the anti-HIV activity of the cyanobacterial Oscillatoria Agardhii agglutinin. Structure (2011) 1.57
Design of a novel peptide inhibitor of HIV fusion that disrupts the internal trimeric coiled-coil of gp41. J Biol Chem (2002) 1.57
Neamphamide A, a new HIV-inhibitory depsipeptide from the Papua New Guinea marine sponge Neamphius huxleyi. J Nat Prod (2004) 1.54
HIV-1 Vpr loads uracil DNA glycosylase-2 onto DCAF1, a substrate recognition subunit of a cullin 4A-ring E3 ubiquitin ligase for proteasome-dependent degradation. J Biol Chem (2010) 1.49
Mechanism of allosteric activation of SAMHD1 by dGTP. Nat Struct Mol Biol (2013) 1.49
Solid-state NMR studies of HIV-1 capsid protein assemblies. J Am Chem Soc (2010) 1.49
Effect of the active site D25N mutation on the structure, stability, and ligand binding of the mature HIV-1 protease. J Biol Chem (2008) 1.44
Novel 2D triple-resonance NMR experiments for sequential resonance assignments of proteins. J Magn Reson (2002) 1.43
The structure of a replication initiator unites diverse aspects of nucleic acid metabolism. Proc Natl Acad Sci U S A (2002) 1.41
Pancreatic duct holder for facilitating duct-to-mucosa pancreatojejunostomy after pancreatoduodenectomy. Am J Surg (2009) 1.41
Risk factors predictive of lymph node metastasis in depressed early gastric cancer. Am J Surg (2002) 1.40
A solution NMR study of the binding kinetics and the internal dynamics of an HIV-1 protease-substrate complex. Protein Sci (2003) 1.39
Probing protein-carbohydrate interactions with microarrays of synthetic oligosaccharides. Chembiochem (2004) 1.38
Mutational and structural studies aimed at characterizing the monomer of HIV-1 protease and its precursor. J Biol Chem (2007) 1.38
A potent novel anti-HIV protein from the cultured cyanobacterium Scytonema varium. Biochemistry (2003) 1.37
The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures. Structure (2002) 1.37
NMR structure of human restriction factor APOBEC3A reveals substrate binding and enzyme specificity. Nat Commun (2013) 1.36
The molecular scaffold kinase suppressor of Ras 1 (KSR1) regulates adipogenesis. Mol Cell Biol (2005) 1.35
Solution NMR structure of the barrier-to-autointegration factor-Emerin complex. J Biol Chem (2007) 1.34
Monomerization of viral entry inhibitor griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity. Structure (2010) 1.33
Multisite and multivalent binding between cyanovirin-N and branched oligomannosides: calorimetric and NMR characterization. Chem Biol (2002) 1.32
Endoscopic full-thickness resection with laparoscopic assistance as hybrid NOTES for gastric submucosal tumor. Surg Endosc (2009) 1.32
Investigation of griffithsin's interactions with human cells confirms its outstanding safety and efficacy profile as a microbicide candidate. PLoS One (2011) 1.30
Effect of sequence polymorphism and drug resistance on two HIV-1 Gag processing sites. Eur J Biochem (2002) 1.30
Combining mutations in HIV-1 protease to understand mechanisms of resistance. Proteins (2002) 1.30
Cyanovirin-N binds to the viral surface glycoprotein, GP1,2 and inhibits infectivity of Ebola virus. Antiviral Res (2003) 1.29
Motions on the millisecond time scale and multiple conformations of HIV-1 capsid protein: implications for structural polymorphism of CA assemblies. J Am Chem Soc (2012) 1.28
Crystal structures of HIV protease V82A and L90M mutants reveal changes in the indinavir-binding site. Eur J Biochem (2004) 1.27
A plant germline-specific integrator of sperm specification and cell cycle progression. PLoS Genet (2009) 1.26
Solution structure of the mature HIV-1 protease monomer: insight into the tertiary fold and stability of a precursor. J Biol Chem (2003) 1.25
Endoscopic treatment or surgery for undifferentiated early gastric cancer? Am J Surg (2004) 1.25
The structure of the cataract-causing P23T mutant of human gammaD-crystallin exhibits distinctive local conformational and dynamic changes. Biochemistry (2009) 1.25
The highly specific carbohydrate-binding protein cyanovirin-N: structure, anti-HIV/Ebola activity and possibilities for therapy. Mini Rev Med Chem (2005) 1.24
A Kruppel-like factor KLF15 contributes fasting-induced transcriptional activation of mitochondrial acetyl-CoA synthetase gene AceCS2. J Biol Chem (2004) 1.24
Measurement of 15N relaxation in the detergent-solubilized tetrameric KcsA potassium channel. J Biomol NMR (2006) 1.23
Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S. J Mol Biol (2005) 1.22
Potent anti-influenza activity of cyanovirin-N and interactions with viral hemagglutinin. Antimicrob Agents Chemother (2003) 1.21
Requirement of fibroblast growth factor 10 in development of white adipose tissue. Genes Dev (2002) 1.21
T7 lytic phage-displayed peptide libraries exhibit less sequence bias than M13 filamentous phage-displayed peptide libraries. Proteomics (2006) 1.20
HIV-1 protease with 20 mutations exhibits extreme resistance to clinical inhibitors through coordinated structural rearrangements. Biochemistry (2012) 1.20
Conformational changes in HIV-1 gp41 in the course of HIV-1 envelope glycoprotein-mediated fusion and inactivation. Biochemistry (2005) 1.20
Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin. Proteins (2007) 1.20
Evolution of cyclic peptide protease inhibitors. Proc Natl Acad Sci U S A (2011) 1.20
Extracting rate coefficients from single-molecule photon trajectories and FRET efficiency histograms for a fast-folding protein. J Phys Chem A (2010) 1.20
The solution NMR structure of Antheraea polyphemus PBP provides new insight into pheromone recognition by pheromone-binding proteins. J Mol Biol (2004) 1.20
Suggestive evidence for Darwinian Selection against asparagine-linked glycans of Plasmodium falciparum and Toxoplasma gondii. Eukaryot Cell (2009) 1.20
Posttranscriptional activation of the transcriptional activator Rob by dipyridyl in Escherichia coli. J Bacteriol (2002) 1.19
Dissecting carbohydrate-Cyanovirin-N binding by structure-guided mutagenesis: functional implications for viral entry inhibition. Protein Eng Des Sel (2006) 1.19
Mapping the binding of the N-terminal extracellular tail of the CXCR4 receptor to stromal cell-derived factor-1alpha. J Mol Biol (2005) 1.18
Development of a cell-based reporter assay for screening of inhibitors of hypoxia-inducible factor 2-induced gene expression. J Biomol Screen (2006) 1.17
Structure and orientation of a G protein fragment in the receptor bound state from residual dipolar couplings. J Mol Biol (2002) 1.17