Published in Lancet on January 12, 2002
Indications for propensity scores and review of their use in pharmacoepidemiology. Basic Clin Pharmacol Toxicol (2006) 4.70
Outcomes with concurrent use of clopidogrel and proton-pump inhibitors: a cohort study. Ann Intern Med (2010) 2.90
Improved comorbidity adjustment for predicting mortality in Medicare populations. Health Serv Res (2003) 2.65
The double-edged sword of COX-2 selective NSAIDs. CMAJ (2002) 2.57
Risk of acute myocardial infarction with nonselective non-steroidal anti-inflammatory drugs: a meta-analysis. Arthritis Res Ther (2006) 1.96
Time variations in the risk of myocardial infarction among elderly users of COX-2 inhibitors. CMAJ (2006) 1.82
Non-steroidal anti-inflammatory drugs and myocardial infarctions: comparative systematic review of evidence from observational studies and randomised controlled trials. Ann Rheum Dis (2007) 1.68
Development and evaluation of a common data model enabling active drug safety surveillance using disparate healthcare databases. J Am Med Inform Assoc (2010) 1.62
Pathological ventricular remodeling: mechanisms: part 1 of 2. Circulation (2013) 1.48
Use of nonsteroidal anti-inflammatory drugs and the risk of first-time acute myocardial infarction. Br J Clin Pharmacol (2002) 1.30
Non-steroidal anti-inflammatory drugs: overall risks and management. Complementary roles for COX-2 inhibitors and proton pump inhibitors. Gut (2003) 1.20
What's all the fuss? Safety concerns about COX-2 inhibitors rofecoxib (Vioxx) and celecoxib (Celebrex). CMAJ (2002) 1.18
No reduction in cardiovascular risk with NSAIDs-including aspirin? Lancet (2002) 1.07
NSAID use selectively increases the risk of non-fatal myocardial infarction: a systematic review of randomised trials and observational studies. PLoS One (2011) 1.04
Macrophages mediate cardioprotective cellular postconditioning in acute myocardial infarction. J Clin Invest (2015) 1.00
On the joint use of propensity and prognostic scores in estimation of the average treatment effect on the treated: a simulation study. Stat Med (2013) 0.99
Risk of new acute myocardial infarction hospitalization associated with use of oral and parenteral non-steroidal anti-inflammation drugs (NSAIDs): a case-crossover study of Taiwan's National Health Insurance claims database and review of current evidence. BMC Cardiovasc Disord (2012) 0.98
Increased risk of myocardial infarction as first manifestation of ischaemic heart disease and nonselective nonsteroidal anti-inflammatory drugs. Br J Clin Pharmacol (2006) 0.93
Platelets and their chemokines in atherosclerosis-clinical applications. Front Physiol (2014) 0.91
Cardiovascular and gastrointestinal effects of COX-2 inhibitors and NSAIDs: achieving a balance. Arthritis Res Ther (2005) 0.89
Non-steroidal anti-inflammatory drugs (NSAIDs) and hypertension treatment intensification: a population-based cohort study. Eur J Clin Pharmacol (2012) 0.86
Cyclooxygenases: mediators of UV-induced skin cancer and potential targets for prevention. J Invest Dermatol (2014) 0.86
Disease risk score as a confounder summary method: systematic review and recommendations. Pharmacoepidemiol Drug Saf (2012) 0.85
Use of non-steroidal anti-inflammatory drugs and risk of incident myocardial infarction and heart failure, and all-cause mortality in the Australian veteran community. Br J Clin Pharmacol (2010) 0.85
Utility of published guidelines on the use of nonsteroidal anti-inflammatory drugs in the elderly. Clin Rheumatol (2008) 0.84
Review of the cardiovascular safety of COXIBs compared to NSAIDS. Cardiovasc J Afr (2008) 0.83
Problem of the atherothrombotic potential of non-steroidal anti-inflammatory drugs. Ann Rheum Dis (2005) 0.81
NSAIDs and Cardiovascular Diseases: Role of Reactive Oxygen Species. Oxid Med Cell Longev (2015) 0.80
Antiplatelet therapy from clinical trials to clinical practice. Clin Med Res (2003) 0.80
Myocardial Infarction and Its Association with the Use of Nonselective NSAIDs: A Nested Case-Control and Time-to-Event Analysis. Perm J (2008) 0.79
Acute coronary disease Athero-Inflammation: Therapeutic approach. Thromb J (2003) 0.78
Non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease. Lancet (2002) 0.78
High-fat diet alters prostanoid balance and perfusion in ischemic myocardium of naproxen-treated swine. Surgery (2011) 0.78
Nonsteroidal Anti-Inflammatory Drug-Induced Gastroduodenal Bleeding: Risk Factors and Prevention Strategies. Pharmaceuticals (Basel) (2010) 0.77
Assessment of the safety of selective cyclo-oxygenase-2 inhibitors: where are we in 2003? Inflammopharmacology (2003) 0.76
Celecoxib in arthritis: relative risk management profile and implications for patients. Ther Clin Risk Manag (2009) 0.76
Regular use of traditional analgesics predicts major coronary events: A cohort study. Ther Clin Risk Manag (2009) 0.75
Antiplatelet therapy in acute coronary syndromes: current agents and impact on patient outcomes. Patient Relat Outcome Meas (2010) 0.75
Effect of ibuprofen on cardioprotective effect of aspirin. Lancet (2003) 0.75
Preemptive Genotyping of CYP2C8 and CYP2C9 Allelic Variants Involved in NSAIDs Metabolism for Sickle Cell Disease Pain Management. Clin Transl Sci (2015) 0.75
Effect of ibuprofen on cardioprotective effect of aspirin. Lancet (2003) 0.75
Effect of ibuprofen on cardioprotective effect of aspirin. Lancet (2003) 0.75
Naproxen aggravates doxorubicin-induced cardiomyopathy in rats. Indian J Pharmacol (2010) 0.75
Discrepancy among observational studies: example of naproxen-associated adverse events. Open Rheumatol J (2009) 0.75
Do NSAIDs inhibit the cardioprotective effects of ASA? CMAJ (2004) 0.75
Current developments in anti-platelet therapy. Wien Med Wochenschr (2006) 0.75
Non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease. Lancet (2002) 0.75
Cox-2: where are we in 2003? - Cardiovascular risk and Cox-2 inhibitors. Arthritis Res Ther (2002) 0.75
Applying a research ethics committee approach to a medical practice controversy: the case of the selective COX-2 inhibitor rofecoxib. J Med Ethics (2004) 0.75
Cardiovascular risk factor analysis in patients with a recent clinical fracture at the fracture liaison service. Biomed Res Int (2014) 0.75
Using Multiple Pharmacovigilance Models Improves the Timeliness of Signal Detection in Simulated Prospective Surveillance. Drug Saf (2017) 0.75
[Pharmacology of cyclooxygenase 2 inhibition]. Wien Med Wochenschr (2003) 0.75
The burden of respiratory syncytial virus infection in young children. N Engl J Med (2009) 8.95
The underrecognized burden of influenza in young children. N Engl J Med (2006) 8.25
Azithromycin and the risk of cardiovascular death. N Engl J Med (2012) 8.18
Atypical antipsychotic drugs and the risk of sudden cardiac death. N Engl J Med (2009) 7.89
Genetic determinants of response to warfarin during initial anticoagulation. N Engl J Med (2008) 7.13
Major congenital malformations after first-trimester exposure to ACE inhibitors. N Engl J Med (2006) 6.83
Oral erythromycin and the risk of sudden death from cardiac causes. N Engl J Med (2004) 6.21
Population-based surveillance for hospitalizations associated with respiratory syncytial virus, influenza virus, and parainfluenza viruses among young children. Pediatrics (2004) 5.74
Decline in pneumonia admissions after routine childhood immunisation with pneumococcal conjugate vaccine in the USA: a time-series analysis. Lancet (2007) 5.50
Antibiotic prescription rates for acute respiratory tract infections in US ambulatory settings. JAMA (2009) 4.61
Premature coronary-artery atherosclerosis in systemic lupus erythematosus. N Engl J Med (2003) 4.58
New drugs for rheumatoid arthritis. N Engl J Med (2004) 4.38
Asthma as a risk factor for invasive pneumococcal disease. N Engl J Med (2005) 4.04
A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose. Blood (2008) 4.02
Evidence of a causal role of winter virus infection during infancy in early childhood asthma. Am J Respir Crit Care Med (2008) 3.84
Burden of interpandemic influenza in children younger than 5 years: a 25-year prospective study. J Infect Dis (2001) 3.73
Improving blood pressure control through provider education, provider alerts, and patient education: a cluster randomized trial. Ann Intern Med (2006) 3.72
Initiation of tumor necrosis factor-α antagonists and the risk of hospitalization for infection in patients with autoimmune diseases. JAMA (2011) 3.58
Rhinovirus-associated hospitalizations in young children. J Infect Dis (2007) 3.35
Superiority of reverse-transcription polymerase chain reaction to conventional viral culture in the diagnosis of acute respiratory tract infections in children. J Infect Dis (2004) 3.25
Increased coronary-artery atherosclerosis in rheumatoid arthritis: relationship to disease duration and cardiovascular risk factors. Arthritis Rheum (2005) 3.17
ADHD drugs and serious cardiovascular events in children and young adults. N Engl J Med (2011) 3.12
Increased concentration of proatherogenic inflammatory cytokines in systemic lupus erythematosus: relationship to cardiovascular risk factors. J Rheumatol (2006) 3.10
Invasive pneumococcal disease among infants before and after introduction of pneumococcal conjugate vaccine. JAMA (2006) 2.93
Effectiveness of seasonal influenza vaccines in the United States during a season with circulation of all three vaccine strains. Clin Infect Dis (2012) 2.91
Outcomes with concurrent use of clopidogrel and proton-pump inhibitors: a cohort study. Ann Intern Med (2010) 2.90
Safety of herpes zoster vaccine in the shingles prevention study: a randomized trial. Ann Intern Med (2010) 2.73
Incidence of invasive pneumococcal disease among individuals with sickle cell disease before and after the introduction of the pneumococcal conjugate vaccine. Clin Infect Dis (2007) 2.60
A novel group of rhinoviruses is associated with asthma hospitalizations. J Allergy Clin Immunol (2008) 2.53
COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease. Lancet (2002) 2.49
Density interactions among Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in the nasopharynx of young Peruvian children. Pediatr Infect Dis J (2013) 2.47
Validation of ICD-9 codes with a high positive predictive value for incident strokes resulting in hospitalization using Medicaid health data. Pharmacoepidemiol Drug Saf (2008) 2.46
Accuracy and interpretation of rapid influenza tests in children. Pediatrics (2007) 2.43
Increasing burden and risk factors for bronchiolitis-related medical visits in infants enrolled in a state health care insurance plan. Pediatrics (2008) 2.29
Maternal asthma and maternal smoking are associated with increased risk of bronchiolitis during infancy. Pediatrics (2007) 2.20
Comparative effectiveness of sulfonylurea and metformin monotherapy on cardiovascular events in type 2 diabetes mellitus: a cohort study. Ann Intern Med (2012) 2.18
Reform of drug regulation--beyond an independent drug-safety board. N Engl J Med (2006) 2.17
Blacks have a greater sensitivity to α1-adrenoceptor-mediated venoconstriction compared with whites. Hypertension (2013) 2.13
Influenza burden for children with asthma. Pediatrics (2008) 2.10
Maternal morbidity and perinatal outcomes among pregnant women with respiratory hospitalizations during influenza season. Am J Obstet Gynecol (2003) 2.09
Increasing incidence of empyema complicating childhood community-acquired pneumonia in the United States. Clin Infect Dis (2010) 2.09
National impact of universal childhood immunization with pneumococcal conjugate vaccine on outpatient medical care visits in the United States. Pediatrics (2006) 2.01
High prevalence of the metabolic syndrome in patients with systemic lupus erythematosus: association with disease characteristics and cardiovascular risk factors. Ann Rheum Dis (2006) 2.00
Relative contribution of CYP2C9 and VKORC1 genotypes and early INR response to the prediction of warfarin sensitivity during initiation of therapy. Blood (2008) 1.99
A computer case definition for sudden cardiac death. Pharmacoepidemiol Drug Saf (2010) 1.97
Antipsychotics and the risk of type 2 diabetes mellitus in children and youth. JAMA Psychiatry (2013) 1.95
Human coronavirus in young children hospitalized for acute respiratory illness and asymptomatic controls. Pediatr Infect Dis J (2012) 1.93
Human rhinovirus species associated with hospitalizations for acute respiratory illness in young US children. J Infect Dis (2011) 1.93
Comparative effectiveness of incident oral antidiabetic drugs on kidney function. Kidney Int (2012) 1.92
The severity-dependent relationship of infant bronchiolitis on the risk and morbidity of early childhood asthma. J Allergy Clin Immunol (2009) 1.91
Cardiovascular risks of nonsteroidal antiinflammatory drugs in patients after hospitalization for serious coronary heart disease. Circ Cardiovasc Qual Outcomes (2009) 1.90
Parainfluenza virus infection of young children: estimates of the population-based burden of hospitalization. J Pediatr (2009) 1.90
Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process. Curr Drug Metab (2014) 1.88
CYP2C9 allelic variants: ethnic distribution and functional significance. Adv Drug Deliv Rev (2002) 1.86
The aprotinin story--is BART the final chapter? N Engl J Med (2008) 1.84
Reduction in high rates of antibiotic-nonsusceptible invasive pneumococcal disease in tennessee after introduction of the pneumococcal conjugate vaccine. Clin Infect Dis (2004) 1.84
Rates of hospitalizations for respiratory syncytial virus, human metapneumovirus, and influenza virus in older adults. J Infect Dis (2012) 1.84
Respiratory syncytial virus-associated hospitalizations among children less than 24 months of age. Pediatrics (2013) 1.83
Risk of peptic ulcer hospitalizations in users of NSAIDs with gastroprotective cotherapy versus coxibs. Gastroenterology (2007) 1.80
Changing epidemiology of pneumococcal meningitis after the introduction of pneumococcal conjugate vaccine in the United States. Clin Infect Dis (2008) 1.80
Obesity is an independent contributor to functional capacity and inflammation in systemic lupus erythematosus. Arthritis Rheum (2005) 1.80
Increasing outpatient fluoroquinolone exposure before tuberculosis diagnosis and impact on culture-negative disease. Arch Intern Med (2007) 1.78
Prospective evaluation of a pharmacogenetics-guided warfarin loading and maintenance dose regimen for initiation of therapy. Blood (2011) 1.77
Failure of routine diagnostic methods to detect influenza in hospitalized older adults. Infect Control Hosp Epidemiol (2010) 1.77
Trends in antibiotic prescribing for adults in the United States--1995 to 2002. J Gen Intern Med (2005) 1.75
Prevalence of the metabolic syndrome is increased in rheumatoid arthritis and is associated with coronary atherosclerosis. Atherosclerosis (2007) 1.73
Prenatal prescription of macrolide antibiotics and infantile hypertrophic pyloric stenosis. Obstet Gynecol (2002) 1.70
Improving medication use in newly admitted home healthcare patients: a randomized controlled trial. J Am Geriatr Soc (2002) 1.69
The burden of influenza in young children, 2004-2009. Pediatrics (2013) 1.68
Seasonality of invasive pneumococcal disease: temporal relation to documented influenza and respiratory syncytial viral circulation. Am J Med (2005) 1.68
Emergence of parapneumonic empyema in the USA. Thorax (2011) 1.67
Cyclic antidepressants and the risk of sudden cardiac death. Clin Pharmacol Ther (2004) 1.67
Burden of human metapneumovirus infection in young children. N Engl J Med (2013) 1.65
Sickle cell trait, hemoglobin C trait, and invasive pneumococcal disease. Epidemiology (2010) 1.63
Inflammation-associated insulin resistance: differential effects in rheumatoid arthritis and systemic lupus erythematosus define potential mechanisms. Arthritis Rheum (2008) 1.63
Associations between CYP2B6 polymorphisms and pharmacokinetics after a single dose of nevirapine or efavirenz in African americans. J Infect Dis (2009) 1.63
Effect of a mental health "carve-out" program on the continuity of antipsychotic therapy. N Engl J Med (2003) 1.63
Assessment of adherence to and persistence on disease-modifying antirheumatic drugs (DMARDs) in patients with rheumatoid arthritis. Med Care (2007) 1.62
Medical care utilization and mortality in sickle cell disease: a population-based study. Am J Hematol (2005) 1.61
Reduction of frequent otitis media and pressure-equalizing tube insertions in children after introduction of pneumococcal conjugate vaccine. Pediatrics (2007) 1.61
Changes in antibiotic prescribing for children after a community-wide campaign. JAMA (2002) 1.59
Resident work hour limits and patient safety. Ann Surg (2005) 1.58
Differences in antibiotic prescribing among physicians, residents, and nonphysician clinicians. Am J Med (2005) 1.58
Vaccine effectiveness against laboratory-confirmed influenza in children 6 to 59 months of age during the 2003-2004 and 2004-2005 influenza seasons. Pediatrics (2008) 1.56