Published in Chem Rev on November 07, 1996
Three metal ions at the active site of the Tetrahymena group I ribozyme. Proc Natl Acad Sci U S A (1999) 1.69
Use of plasmon coupling to reveal the dynamics of DNA bending and cleavage by single EcoRV restriction enzymes. Proc Natl Acad Sci U S A (2007) 1.59
DNA-catalyzed sequence-specific hydrolysis of DNA. Nat Chem Biol (2009) 1.54
The crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, defines a third class of sulfatases. Proc Natl Acad Sci U S A (2006) 1.39
Comparative enzymology in the alkaline phosphatase superfamily to determine the catalytic role of an active-site metal ion. J Mol Biol (2008) 1.19
Protein design: toward functional metalloenzymes. Chem Rev (2014) 1.17
Structural basis of catalysis by monometalated methionine aminopeptidase. Proc Natl Acad Sci U S A (2006) 1.17
Alkaline phosphatase mono- and diesterase reactions: comparative transition state analysis. J Am Chem Soc (2006) 1.15
Unraveling the three-metal-ion catalytic mechanism of the DNA repair enzyme endonuclease IV. Proc Natl Acad Sci U S A (2007) 1.14
Characterization of native and recombinant forms of an unusual cobalt-dependent proline dipeptidase (prolidase) from the hyperthermophilic archaeon Pyrococcus furiosus. J Bacteriol (1998) 1.13
Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli. Proc Natl Acad Sci U S A (1998) 1.13
Phosphate forms an unusual tripodal complex with the Fe-Mn center of sweet potato purple acid phosphatase. Proc Natl Acad Sci U S A (2004) 1.12
A two-metal ion mechanism operates in the hammerhead ribozyme-mediated cleavage of an RNA substrate. Proc Natl Acad Sci U S A (1998) 1.06
Functional identification of catalytic metal ion binding sites within RNA. PLoS Biol (2005) 1.05
An unconventional origin of metal-ion rescue and inhibition in the Tetrahymena group I ribozyme reaction. RNA (2000) 1.01
Modeling Structural Coordination and Ligand Binding in Zinc Proteins with a Polarizable Potential. J Chem Theory Comput (2012) 1.01
Evidence for a hydroxide ion bridging two magnesium ions at the active site of the hammerhead ribozyme. Nucleic Acids Res (1997) 0.99
Crystal structure of aminopeptidase N from human pathogen Neisseria meningitidis. Proteins (2008) 0.99
Metal ion-dependent hydrolysis of RNA phosphodiester bonds within hairpin loops. A comparative kinetic study on chimeric ribo/2'-O-methylribo oligonucleotides. Nucleic Acids Res (1998) 0.99
Probing the origin of the compromised catalysis of E. coli alkaline phosphatase in its promiscuous sulfatase reaction. J Am Chem Soc (2007) 0.98
Catalysis and inhibition of Mycobacterium tuberculosis methionine aminopeptidase. J Med Chem (2010) 0.98
Merely two mutations switch a DNA-hydrolyzing deoxyribozyme from heterobimetallic (Zn2+/Mn2+) to monometallic (Zn2+-only) behavior. Chem Commun (Camb) (2010) 0.98
Crystal structures of Wzb of Escherichia coli and CpsB of Streptococcus pneumoniae, representatives of two families of tyrosine phosphatases that regulate capsule assembly. J Mol Biol (2009) 0.94
Promiscuous sulfatase activity and thio-effects in a phosphodiesterase of the alkaline phosphatase superfamily. Biochemistry (2008) 0.93
Synthetic modeling of zinc thiolates: quantitative assessment of hydrogen bonding in modulating sulfur alkylation rates. Proc Natl Acad Sci U S A (2003) 0.93
Determination of binding affinity of metal cofactor to the active site of methionine aminopeptidase based on quantitation of functional enzyme. Anal Biochem (2009) 0.92
Crystal structures of a purple acid phosphatase, representing different steps of this enzyme's catalytic cycle. BMC Struct Biol (2008) 0.91
The high-resolution structures of the neutral and the low pH crystals of aminopeptidase from Aeromonas proteolytica. J Biol Inorg Chem (2006) 0.91
Expression and characterization of Mycobacterium tuberculosis methionine aminopeptidase type 1a. Bioorg Med Chem Lett (2010) 0.88
Structurally distinct active sites in the copper(II)-substituted aminopeptidases from Aeromonas proteolytica and Escherichia coli. J Am Chem Soc (2002) 0.87
Identifying the structure of the active sites of human recombinant prolidase. Eur Biophys J (2009) 0.86
Zinc and antibiotic resistance: metallo-beta-lactamases and their synthetic analogues. J Biol Inorg Chem (2008) 0.85
Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenes. J Am Chem Soc (2008) 0.84
Characterization of the active site and insight into the binding mode of the anti-angiogenesis agent fumagillin to the manganese(II)-loaded methionyl aminopeptidase from Escherichia coli. J Biol Inorg Chem (2004) 0.82
DNA-catalyzed hydrolysis of DNA phosphodiesters. Nat Chem Biol (2009) 0.82
Mechanism of peptide hydrolysis by co-catalytic metal centers containing leucine aminopeptidase enzyme: a DFT approach. J Biol Inorg Chem (2011) 0.81
New macrocyclic terbium(III) complex for use in RNA footprinting experiments. J Am Chem Soc (2009) 0.81
Probing the role of the divalent metal ion in uteroferrin using metal ion replacement and a comparison to isostructural biomimetics. J Biol Inorg Chem (2007) 0.81
Dinickel Bisphenoxyiminato Complexes for the Polymerization of Ethylene and α-Olefins. Organometallics (2012) 0.80
Pneumococcal phosphorylcholine esterase, Pce, contains a metal binuclear center that is essential for substrate binding and catalysis. Protein Sci (2005) 0.80
Specific targeting of the metallophosphoesterase YkuE to the bacillus cell wall requires the twin-arginine translocation system. J Biol Chem (2012) 0.80
Analysis of the stoichiometric metal activation of methionine aminopeptidase. BMC Biochem (2009) 0.78
Characterization of the catalytically active Mn(II)-loaded argE-encoded N-acetyl-L-ornithine deacetylase from Escherichia coli. J Biol Inorg Chem (2007) 0.78
Characterization of an aminoacylase from the hyperthermophilic archaeon Pyrococcus furiosus. J Bacteriol (2001) 0.78
The structure of RdDddP from Roseobacter denitrificans reveals that DMSP lyases in the DddP-family are metalloenzymes. PLoS One (2014) 0.78
Immobilization of the aminopeptidase from Aeromonas proteolytica on Mg2+/Al3+ layered double hydroxide particles. ACS Appl Mater Interfaces (2010) 0.77
Analyzing the catalytic role of Asp97 in the methionine aminopeptidase from Escherichia coli. FEBS J (2008) 0.77
Distinct metal ion requirements for the phosphomonoesterase and phosphodiesterase activities of calf intestinal alkaline phosphatase. Open Biochem J (2011) 0.77
Structural basis of substrate selectivity of E. coli prolidase. PLoS One (2014) 0.77
Catalytic zinc complexes for phosphate diester hydrolysis. Angew Chem Int Ed Engl (2014) 0.77
A new heterobinuclear FeIIICuII complex with a single terminal FeIII-O(phenolate) bond. Relevance to purple acid phosphatases and nucleases. J Biol Inorg Chem (2005) 0.76
Advances in Bacterial Methionine Aminopeptidase Inhibition. Curr Top Med Chem (2016) 0.76
Use of magnetic circular dichroism to study dinuclear metallohydrolases and the corresponding biomimetics. Eur Biophys J (2015) 0.76
Identification and characterization of a novel phosphodiesterase from the metagenome of an Indian coalbed. PLoS One (2015) 0.75
Metal Ion Modeling Using Classical Mechanics. Chem Rev (2017) 0.75
The divalent metal ion in the active site of uteroferrin modulates substrate binding and catalysis. J Am Chem Soc (2010) 0.75
Computational validation of 3-ammonio-3-(4-oxido- 1H-imidazol-1-ium-5-yl) propane-1, 1-bis (olate) as a potent anti-tubercular drug against mt-MetAP. Bioinformation (2012) 0.75
A peptide template as an allosteric supramolecular catalyst for the cleavage of phosphate esters. Proc Natl Acad Sci U S A (2002) 0.75
Asymmetric bisboranes as bidentate catalysts for carbonyl substrates. Org Lett (2009) 0.75
Characterization of LlaKI, a New Metal Ion-Independent Restriction Endonuclease from Lactococcus lactis KLDS4. ISRN Biochem (2012) 0.75
Isotope effect analyses provide evidence for an altered transition state for RNA 2'-O-transphosphorylation catalyzed by Zn(2.). Chem Commun (Camb) (2016) 0.75
Molecular design of an acid-base cooperative catalyst for RNA cleavage based on a dizinc complex. J Biol Inorg Chem (2004) 0.75
Determination of the catalytic activity of binuclear metallohydrolases using isothermal titration calorimetry. J Biol Inorg Chem (2014) 0.75
Elucidation of insulin degrading enzyme catalyzed site specific hydrolytic cleavage of amyloid beta peptide: a comparative density functional theory study. J Biol Inorg Chem (2009) 0.75