Published in BMC Struct Biol on January 31, 2008
Purple Acid Phosphatase5 is required for maintaining basal resistance against Pseudomonas syringae in Arabidopsis. BMC Plant Biol (2013) 0.87
Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenes. J Am Chem Soc (2008) 0.84
Fluoride inhibition of Sporosarcina pasteurii urease: structure and thermodynamics. J Biol Inorg Chem (2014) 0.80
Electronic and geometric structures of the organophosphate-degrading enzyme from Agrobacterium radiobacter (OpdA). J Biol Inorg Chem (2011) 0.79
The structure of a purple acid phosphatase involved in plant growth and pathogen defence exhibits a novel immunoglobulin-like fold. IUCrJ (2014) 0.79
Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal-ion preference. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.79
Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH). J Biol Inorg Chem (2014) 0.77
Identification and characterization of an unusual metallo-β-lactamase from Serratia proteamaculans. J Biol Inorg Chem (2013) 0.77
Optimal level of purple acid phosphatase5 is required for maintaining complete resistance to Pseudomonas syringae. Front Plant Sci (2015) 0.75
The divalent metal ion in the active site of uteroferrin modulates substrate binding and catalysis. J Am Chem Soc (2010) 0.75
Catalytic scaffolds for phosphoryl group transfer. Curr Opin Struct Biol (2016) 0.75
Cadmium(II) complexes of the glycerophosphodiester-degrading enzyme GpdQ and a biomimetic N,O ligand. J Biol Inorg Chem (2008) 0.75
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Structurally distinct active sites in the copper(II)-substituted aminopeptidases from Aeromonas proteolytica and Escherichia coli. J Am Chem Soc (2002) 0.87
Evidence for nonbridged coordination of p-nitrophenyl phosphate to the dinuclear Fe(III)-M(II) center in bovine spleen purple acid phosphatase during enzymatic turnover. Biochemistry (1999) 0.86
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Identification and molecular modeling of a novel, plant-like, human purple acid phosphatase. Gene (2006) 0.85
The highly exposed loop region in mammalian purple acid phosphatase controls the catalytic activity. Chembiochem (2001) 0.84
Electro-nuclear double resonance spectroscopic evidence for a hydroxo-bridge nucleophile involved in catalysis by a dinuclear hydrolase. J Am Chem Soc (2002) 0.84
Reactivity of M(II) metal-substituted derivatives of pig purple acid phosphatase (uteroferrin) with phosphate. Inorg Chem (2002) 0.83
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An unprecedented Fe(III)(mu-OH)Zn(II) complex that mimics the structural and functional properties of purple acid phosphatases. J Am Chem Soc (2007) 0.81
The reaction mechanism of the Ga(III)Zn(II) derivative of uteroferrin and corresponding biomimetics. J Biol Inorg Chem (2007) 0.81
Probing the role of the divalent metal ion in uteroferrin using metal ion replacement and a comparison to isostructural biomimetics. J Biol Inorg Chem (2007) 0.81
Recombinant purple acid phosphatase isoform 3 from sweet potato is an enzyme with a diiron metal center. FEBS J (2006) 0.80
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Direct observation of multiple protonation states in recombinant human purple acid phosphatase. J Biol Inorg Chem (2005) 0.77
Direct electrochemistry of porcine purple acid phosphatase (uteroferrin). Biochemistry (2004) 0.76
New insights into the mechanism of purple acid phosphatase through (1)H NMR spectroscopy of the recombinant human enzyme. J Am Chem Soc (2002) 0.76
The catalytic mechanisms of binuclear metallohydrolases. Chem Rev (2006) 1.50
Structure and mechanism of inhibition of plant acetohydroxyacid synthase. Plant Physiol Biochem (2008) 1.45
Crystal structure of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors. J Mol Biol (2002) 1.24
Herbicide-binding sites revealed in the structure of plant acetohydroxyacid synthase. Proc Natl Acad Sci U S A (2006) 1.21
Molecular basis of sulfonylurea herbicide inhibition of acetohydroxyacid synthase. J Biol Chem (2002) 1.16
Anomalous scattering analysis of Agrobacterium radiobacter phosphotriesterase: the prominent role of iron in the heterobinuclear active site. Biochem J (2006) 1.14
Structure-activity relationships for a new family of sulfonylurea herbicides. J Comput Aided Mol Des (2005) 1.13
Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthase. Biochemistry (2005) 1.12
Phosphate forms an unusual tripodal complex with the Fe-Mn center of sweet potato purple acid phosphatase. Proc Natl Acad Sci U S A (2004) 1.12
The crystal structures of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate. J Biol Chem (2003) 1.08
Electronic and spectroscopic studies of the non-heme reduced binuclear iron sites of two ribonucleotide reductase variants: comparison to reduced methane monooxygenase and contributions to O2 reactivity. J Am Chem Soc (2004) 1.05
Structure of CcmG/DsbE at 1.14 A resolution: high-fidelity reducing activity in an indiscriminately oxidizing environment. Structure (2002) 1.05
Spectroscopic and kinetic studies of PKU-inducing mutants of phenylalanine hydroxylase: Arg158Gln and Glu280Lys. J Am Chem Soc (2003) 1.03
Diesterase activity and substrate binding in purple acid phosphatases. J Am Chem Soc (2007) 0.96
Systematic characterization of mutations in yeast acetohydroxyacid synthase. Interpretation of herbicide-resistance data. Eur J Biochem (2003) 0.95
Three-dimensional structure of an immunoglobulin light-chain dimer with amyloidogenic properties. Acta Crystallogr D Biol Crystallogr (2002) 0.94
X-ray absorption spectroscopic investigation of the resting ferrous and cosubstrate-bound active sites of phenylalanine hydroxylase. Biochemistry (2002) 0.93
The crystal structure of a bacterial class II ketol-acid reductoisomerase: domain conservation and evolution. Protein Sci (2005) 0.93
Binuclear metallohydrolases: complex mechanistic strategies for a simple chemical reaction. Acc Chem Res (2012) 0.90
Copper(II) coordination chemistry of westiellamide and its imidazole, oxazole, and thiazole analogues. Chemistry (2008) 0.89
Role of human hypoxanthine guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir). Mol Pharmacol (2013) 0.89
Synthesis and structural properties of patellamide A derivatives and their copper(II) compounds. Chemistry (2002) 0.89
Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: a new class of antimalarial therapeutics. J Med Chem (2009) 0.88
Plant collagenase: unique collagenolytic activity of cysteine proteases from ginger. Biochim Biophys Acta (2007) 0.87
Crystal structure of textilinin-1, a Kunitz-type serine protease inhibitor from the venom of the Australian common brown snake (Pseudonaja textilis). FEBS J (2009) 0.87
Metal-ion mutagenesis: conversion of a purple acid phosphatase from sweet potato to a neutral phosphatase with the formation of an unprecedented catalytically competent Mn(II)Mn(II) active site. J Am Chem Soc (2009) 0.86
Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenes. J Am Chem Soc (2008) 0.84
Conformational changes in a plant ketol-acid reductoisomerase upon Mg(2+) and NADPH binding as revealed by two crystal structures. J Mol Biol (2009) 0.84
Probing the mechanism of the bifunctional enzyme ketol-acid reductoisomerase by site-directed mutagenesis of the active site. FEBS J (2005) 0.83
Inhibition of the Escherichia coli 6-oxopurine phosphoribosyltransferases by nucleoside phosphonates: potential for new antibacterial agents. J Med Chem (2013) 0.83
The crystal structure of free human hypoxanthine-guanine phosphoribosyltransferase reveals extensive conformational plasticity throughout the catalytic cycle. J Mol Biol (2005) 0.83
Phosphotyrosyl peptides and analogues as substrates and inhibitors of purple acid phosphatases. Arch Biochem Biophys (2004) 0.83
Phosphate-bound structure of an organophosphate-degrading enzyme from Agrobacterium radiobacter. J Inorg Biochem (2011) 0.83
Structural flexibility enhances the reactivity of the bioremediator glycerophosphodiesterase by fine-tuning its mechanism of hydrolysis. J Am Chem Soc (2009) 0.82
Directed evolution combined with rational design increases activity of GpdQ toward a non-physiological substrate and alters the oligomeric structure of the enzyme. Protein Eng Des Sel (2011) 0.82
Formation of mononuclear and chloro-bridged binuclear copper(II) complexes of patellamide D, a naturally occurring cyclic peptide: influence of anion and solvent. J Inorg Biochem (2004) 0.82
Probing the role of the divalent metal ion in uteroferrin using metal ion replacement and a comparison to isostructural biomimetics. J Biol Inorg Chem (2007) 0.81
The reaction mechanism of the Ga(III)Zn(II) derivative of uteroferrin and corresponding biomimetics. J Biol Inorg Chem (2007) 0.81
Synthesis of novel N-branched acyclic nucleoside phosphonates as potent and selective inhibitors of human, Plasmodium falciparum and Plasmodium vivax 6-oxopurine phosphoribosyltransferases. J Med Chem (2012) 0.81
Bacterial and plant ketol-acid reductoisomerases have different mechanisms of induced fit during the catalytic cycle. J Mol Biol (2012) 0.81
Synthesis and characterization of the tetranuclear iron(III) complex of a new asymmetric multidentate ligand. A structural model for purple acid phosphatases. Dalton Trans (2007) 0.81
Crystal structures of two novel sulfonylurea herbicides in complex with Arabidopsis thaliana acetohydroxyacid synthase. FEBS J (2009) 0.80
Spectroscopic characterization of the active Fe(III)Fe(III) and Fe(III)Fe(II) forms of a purple acid phosphatase model system. Inorg Chem (2012) 0.80
Mutation of outer-shell residues modulates metal ion co-ordination strength in a metalloenzyme. Biochem J (2010) 0.80
Phosphate ester cleavage promoted by a tetrameric iron(III) complex. J Biol Inorg Chem (2010) 0.79
Cyclic peptide marine metabolites and CuII. Dalton Trans (2014) 0.79
Electronic and geometric structures of the organophosphate-degrading enzyme from Agrobacterium radiobacter (OpdA). J Biol Inorg Chem (2011) 0.79
The role of Zn-OR and Zn-OH nucleophiles and the influence of para-substituents in the reactions of binuclear phosphatase mimetics. Dalton Trans (2011) 0.79
Penicillin inhibitors of purple acid phosphatase. Bioorg Med Chem Lett (2012) 0.79
Studies of the interaction of potassium(I), calcium(II), magnesium(II), and copper(II) with cyclosporin A. J Inorg Biochem (2003) 0.79
Structural and catalytic characterization of a heterovalent Mn(II)Mn(III) complex that mimics purple acid phosphatases. Inorg Chem (2009) 0.79
Electronic structure analysis of the dinuclear metal center in the bioremediator glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes. Inorg Chem (2010) 0.79
Identification of purple acid phosphatase inhibitors by fragment-based screening: promising new leads for osteoporosis therapeutics. Chem Biol Drug Des (2012) 0.78
Dinuclear Zn(II) and mixed Cu(II)-Zn(II) complexes of artificial patellamides as phosphatase models. Dalton Trans (2016) 0.78
Lead compounds for antimalarial chemotherapy: purine base analogs discriminate between human and P. falciparum 6-oxopurine phosphoribosyltransferases. J Med Chem (2006) 0.78
Facile crystallization of Escherichia coli ketol-acid reductoisomerase. Acta Crystallogr D Biol Crystallogr (2004) 0.78
Plasmodium vivax hypoxanthine-guanine phosphoribosyltransferase: a target for anti-malarial chemotherapy. Mol Biochem Parasitol (2010) 0.78
The organophosphate-degrading enzyme from Agrobacterium radiobacter displays mechanistic flexibility for catalysis. Biochem J (2010) 0.78
Identification of a non-purple tartrate-resistant acid phosphatase: an evolutionary link to Ser/Thr protein phosphatases? BMC Res Notes (2008) 0.77
Synthesis of purine N9-[2-hydroxy-3-O-(phosphonomethoxy)propyl] derivatives and their side-chain modified analogs as potential antimalarial agents. Bioorg Med Chem (2011) 0.77
Promiscuity comes at a price: catalytic versatility vs efficiency in different metal ion derivatives of the potential bioremediator GpdQ. Biochim Biophys Acta (2012) 0.77
Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexes. Dalton Trans (2013) 0.77
Acyclic nucleoside phosphonates containing a second phosphonate group are potent inhibitors of 6-oxopurine phosphoribosyltransferases and have antimalarial activity. J Med Chem (2013) 0.77
Synthesis, magnetic properties, and phosphoesterase activity of dinuclear cobalt(II) complexes. Inorg Chem (2013) 0.77
6-oxopurine phosphoribosyltransferase: a target for the development of antimalarial drugs. Curr Top Med Chem (2011) 0.77
Inhibition of purple acid phosphatase with alpha-alkoxynaphthylmethylphosphonic acids. Bioorg Med Chem Lett (2008) 0.77
Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH). J Biol Inorg Chem (2014) 0.77
Sulfonylureas have antifungal activity and are potent inhibitors of Candida albicans acetohydroxyacid synthase. J Med Chem (2012) 0.77
Synthesis of 9-phosphonoalkyl and 9-phosphonoalkoxyalkyl purines: evaluation of their ability to act as inhibitors of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases. Bioorg Med Chem (2011) 0.77
Monoesterase activity of a purple acid phosphatase mimic with a cyclam platform. Chemistry (2012) 0.77
The bioremediator glycerophosphodiesterase employs a non-processive mechanism for hydrolysis. J Inorg Biochem (2009) 0.76
Carbonic anhydrase activity of dinuclear Cu(II) complexes with patellamide model ligands. Dalton Trans (2014) 0.76
A new heterobinuclear FeIIICuII complex with a single terminal FeIII-O(phenolate) bond. Relevance to purple acid phosphatases and nucleases. J Biol Inorg Chem (2005) 0.76
Cu(II) coordination chemistry of patellamide derivatives: possible biological functions of cyclic pseudopeptides. Chemistry (2012) 0.76
The structure of human microplasmin in complex with textilinin-1, an aprotinin-like inhibitor from the Australian brown snake. PLoS One (2013) 0.76
Synthesis, conformational studies, and biological properties of phosphonomethoxyethyl derivatives of nucleobases with a locked conformation via a pyrrolidine ring. Org Biomol Chem (2015) 0.76
Unsymmetrical Fe(III)Co(II) and Ga(III)Co(II) complexes as chemical hydrolases: biomimetic models for purple acid phosphatases (PAPs). Inorg Chem (2009) 0.76
Electronic structure and spectro-structural correlations of Fe(III)Zn(II) biomimetics for purple acid phosphatases: relevance to DNA cleavage and cytotoxic activity. Inorg Chem (2010) 0.76
Extent of charge screening in aqueous polysaccharide solutions. Biomacromolecules (2004) 0.75
Structural and spectroscopic studies of a model for catechol oxidase. J Biol Inorg Chem (2008) 0.75
The divalent metal ion in the active site of uteroferrin modulates substrate binding and catalysis. J Am Chem Soc (2010) 0.75
Crystallization and preliminary X-ray analysis of a Kunitz-type inhibitor, textilinin-1 from Pseudonaja textilis textilis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.75
Cadmium(II) complexes of the glycerophosphodiester-degrading enzyme GpdQ and a biomimetic N,O ligand. J Biol Inorg Chem (2008) 0.75
Determination of the catalytic activity of binuclear metallohydrolases using isothermal titration calorimetry. J Biol Inorg Chem (2014) 0.75
Dinuclear zinc(II) complexes with hydrogen bond donors as structural and functional phosphatase models. Inorg Chem (2014) 0.75
The effect of novel [3-fluoro-(2-phosphonoethoxy)propyl]purines on the inhibition of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases. Eur J Med Chem (2013) 0.75
Spectroscopic and catalytic characterization of a functional Fe(III)Fe(II) biomimetic for the active site of uteroferrin and protein cleavage. Inorg Chem (2012) 0.75