Published in J Control Release on February 19, 2002
Absorption enhancers for nasal drug delivery. Clin Pharmacokinet (2003) 0.95
Preparation and characterization of nicotine-magnesium aluminum silicate complex-loaded sodium alginate matrix tablets for buccal delivery. AAPS PharmSciTech (2011) 0.81
Thermoreversible nasal in situ gel of venlafaxine hydrochloride: formulation, characterization, and pharmacodynamic evaluation. AAPS PharmSciTech (2012) 0.75
Influence of pH modifiers and HPMC viscosity grades on nicotine-magnesium aluminum silicate complex-loaded buccal matrix tablets. AAPS PharmSciTech (2012) 0.75
Palatability and physical properties of potassium-binding resin RDX7675: comparison with sodium polystyrene sulfonate. Drug Des Devel Ther (2017) 0.75
Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell (1998) 19.05
Explaining variation in general practitioner referrals to hospital. Fam Pract (1987) 10.27
Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev (1998) 8.51
Prevalence of antibodies to human immunodeficiency virus, gonorrhoea rates, and changed sexual behaviour in homosexual men in London. Lancet (1987) 7.71
Altered immune responses in mice lacking inducible nitric oxide synthase. Nature (1995) 6.20
Integrated care pathways. BMJ (1998) 6.14
Effect of HIV-1 and increasing immunosuppression on malaria parasitaemia and clinical episodes in adults in rural Uganda: a cohort study. Lancet (2000) 5.93
Assessing completeness of cancer registration in the north-western region of England by a method of independent comparison. Br J Cancer (1982) 4.90
14 years of follow-up from the Edinburgh randomised trial of breast-cancer screening. Lancet (1999) 4.80
Relation of particle dimension to carcinogenicity in amphibole asbestoses and other fibrous minerals. J Natl Cancer Inst (1981) 4.60
Fourth International Consultation on Incontinence Recommendations of the International Scientific Committee: Evaluation and treatment of urinary incontinence, pelvic organ prolapse, and fecal incontinence. Neurourol Urodyn (2010) 4.48
Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression. Proc Natl Acad Sci U S A (1994) 4.44
Microchimerism and HLA-compatible relationships of pregnancy in scleroderma. Lancet (1998) 4.44
The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways. Nat Neurosci (1999) 4.35
Smoking habits of oral contraceptive users. Lancet (1969) 4.20
Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells. Dev Biol (1999) 4.00
Major-histocompatibility-complex class I alleles and antigens in hematopoietic-cell transplantation. N Engl J Med (2001) 3.98
Detection in life of confirmed Alzheimer's disease using a simple measurement of medial temporal lobe atrophy by computed tomography. Lancet (1992) 3.94
Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice. Science (1999) 3.85
Campylobacter pyloridis in peptic ulcer disease: microbiology, pathology, and scanning electron microscopy. Gut (1985) 3.48
Identification of the NH2-terminal blocking group of calcineurin B as myristic acid. FEBS Lett (1982) 3.42
Acceptors and rejectors of an invitation to undergo breast screening compared with those who referred themselves. J Epidemiol Community Health (1980) 2.95
Caesarean scar pregnancy. BJOG (2007) 2.77
Predicting successful vaginal birth after Cesarean section using a model based on Cesarean scar features examined by transvaginal sonography. Ultrasound Obstet Gynecol (2013) 2.73
Does it matter where you live? Treatment variation for breast cancer in Yorkshire. The Yorkshire Breast Cancer Group. Br J Cancer (1995) 2.71
Audit commission tackles anaesthetic services. BMJ (1998) 2.70
Contrast extravasation on CT predicts mortality in primary intracerebral hemorrhage. AJNR Am J Neuroradiol (2007) 2.69
Delay in breast cancer and the nature of presenting symptoms. Lancet (1981) 2.67
A radiation hybrid map of the rat genome containing 5,255 markers. Nat Genet (1999) 2.54
Exhaled breath condensate pH is a robust and reproducible assay of airway acidity. Eur Respir J (2003) 2.51
The effect of adjunctive fresh frozen plasma administration on coagulation parameters and survival in a canine model of antivenom-treated brown snake envenoming. Anaesth Intensive Care (2005) 2.49
Prospective randomized clinical trial of the value of intraperitoneal drainage after pancreatic resection. Ann Surg (2001) 2.47
Oral contraceptives and venous thromboembolism: findings in a large prospective study. Br Med J (Clin Res Ed) (1986) 2.47
A national health service and the public health. Public Health (1988) 2.46
On-site HIV testing in resource-poor settings: is one rapid test enough? AIDS (1997) 2.39
Transit of pharmaceutical dosage forms through the small intestine. Gut (1986) 2.35
Randomised controlled trial of self management leaflets and booklets for minor illness provided by post. BMJ (2001) 2.35
Microchimerism of maternal origin persists into adult life. J Clin Invest (1999) 2.35
Anxiety disorders in cancer patients: their nature, associations, and relation to quality of life. J Clin Oncol (2002) 2.34
Antimicrobial resistance: Antibiotics and consultant oral microbiologist posts. Br Dent J (2016) 2.32
Recommendations for conducting the in vivo alkaline Comet assay. 4th International Comet Assay Workshop. Mutagenesis (2003) 2.29
Clinical pharmacology clinics in general practice. Br Med J (1977) 2.28
Acute encephalopathy coincident with seroconversion for anti-HTLV-III. Lancet (1985) 2.26
Qualms about QALYs. Lancet (1987) 2.26
Early pulmonary infection, inflammation, and clinical outcomes in infants with cystic fibrosis. Pediatr Pulmonol (2001) 2.24
Generation of purified neural precursors from embryonic stem cells by lineage selection. Curr Biol (1998) 2.20
Childhood-onset schizophrenia. Progressive ventricular change during adolescence. Arch Gen Psychiatry (1997) 2.15
Isolation of stable mouse cell lines that express cell surface and secreted forms of the vesicular stomatitis virus glycoprotein. J Cell Biol (1983) 2.14
A quantitative assessment of residual protein levels on dental instruments reprocessed by manual, ultrasonic and automated cleaning methods. Br Dent J (2011) 2.13
Non-invasive markers of bone turnover and plasma cytokines differ in osteoporotic patients with multiple myeloma and monoclonal gammopathies of undetermined significance. Intern Med J (2001) 2.12
PLGA nanoparticles prepared by nanoprecipitation: drug loading and release studies of a water soluble drug. J Control Release (1999) 2.08
Cross infection control measures and the treatment of patients at risk of Creutzfeldt Jakob disease in UK general dental practice. Br Dent J (2001) 2.08
Outcome of elective prostatectomy. BMJ (1989) 2.08
The endocrinology of the menopausal transition: a cross-sectional study of a population-based sample. J Clin Endocrinol Metab (1995) 2.07
Maintenance of the pluripotential phenotype of embryonic stem cells through direct activation of gp130 signalling pathways. Mech Dev (1994) 2.07
Sequence of the preprotoxin dsRNA gene of type I killer yeast: multiple processing events produce a two-component toxin. Cell (1984) 2.03
A verandah-trap hut for studying the house-frequenting habits of mosquitoes and for assessing insecticides. 3. The effect of DDT on behavior and mortality. Bull Entomol Res (1969) 2.03
The management of acute abdominal pain in children. J Paediatr Child Health (1996) 2.02
Does the presence of a cesarean section scar influence the site of placental implantation and subsequent migration in future pregnancies: a prospective case-control study. Ultrasound Obstet Gynecol (2012) 1.98
Phase I clinical trial of the flavonoid quercetin: pharmacokinetics and evidence for in vivo tyrosine kinase inhibition. Clin Cancer Res (1996) 1.95
The cardiac conduction system in situs ambiguus. Circulation (1979) 1.92
"Multidimensionally impaired disorder": is it a variant of very early-onset schizophrenia? J Am Acad Child Adolesc Psychiatry (1998) 1.90
Human immunodeficiency viruses in patients attending a sexually transmitted disease clinic in London, 1982-7. BMJ (1989) 1.89
Chitosan as a novel nasal delivery system for vaccines. Adv Drug Deliv Rev (2001) 1.87
Sleep and behavior problems among preschoolers. J Dev Behav Pediatr (1999) 1.86
Defining a pulmonary exacerbation in cystic fibrosis. J Pediatr (2001) 1.83
Atresia of the right atrioventricular orifice. Br Heart J (1977) 1.82
Critical incident reports concerning anaesthetic equipment: analysis of the UK National Reporting and Learning System (NRLS) data from 2006-2008*. Anaesthesia (2011) 1.81
Vocational training for general practice: a preliminary report. Br Med J (1971) 1.79
Psychosocial, lifestyle, and health status variables in predicting high attendance among adults. Br J Gen Pract (2001) 1.76
Relative roles of plaques and tangles in the dementia of Alzheimer's disease: correlations using three sets of neuropathological criteria. Dementia (1995) 1.76
Essential function of LIF receptor in motor neurons. Nature (1995) 1.74
Risk of scrapie in British sheep of different prion protein genotype. J Gen Virol (2004) 1.73
Characterization of cDNAs encoding two isoforms of granule-bound starch synthase which show differential expression in developing storage organs of pea and potato. Plant J (1992) 1.72
Summing up. Postgrad Med J (1984) 1.72
Iris melanoma: risk factors for metastasis in 169 consecutive patients. Ophthalmology (2001) 1.72
Anti-Mullerian hormone-tailored stimulation protocols improve outcomes whilst reducing adverse effects and costs of IVF. Hum Reprod (2011) 1.72
Psychiatrists' models of mental illness and their personal backgrounds. Psychol Med (1979) 1.70
Midazolam--an anti-emetic? Anaesthesia (2002) 1.70
The proto-oncogene/translation factor eIF4E: a survey of its expression in breast carcinomas. Int J Cancer (1995) 1.68
Factors associated with speed of diagnosis, referral, and treatment in colorectal cancer. J Epidemiol Community Health (1984) 1.68
Hypothesis: common bacterial toxins are a possible cause of the sudden infant death syndrome. Med Hypotheses (1987) 1.65
Iatrogenic thoracic migration of the stomach complicating laparoscopic nissen fundoplication. Surg Endosc (2000) 1.65
Occurrence of the alpha thalassaemia-mental retardation syndrome (non-deletional type) in an Australian male. J Med Genet (1990) 1.63
Floating dosage forms: an in vivo study demonstrating prolonged gastric retention. J Control Release (1998) 1.62
Peripheral demyelination and neuropathic pain behavior in periaxin-deficient mice. Neuron (2000) 1.61
Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2). Pharm Res (1994) 1.61
Predictors of successful extubation in neurosurgical patients. Am J Respir Crit Care Med (2001) 1.61
Factors influencing bowel function after ileal pouch-anal anastomosis. Br J Surg (1986) 1.60
Tumor development in the Beckwith-Wiedemann syndrome is associated with a variety of constitutional molecular 11p15 alterations including imprinting defects of KCNQ1OT1. Hum Mol Genet (2001) 1.58
A Shannon entropy analysis of immunoglobulin and T cell receptor. Mol Immunol (1997) 1.58
Type 2 diabetes in obese white children. Arch Dis Child (2002) 1.57
Physiological rationale for responsiveness of mouse embryonic stem cells to gp130 cytokines. Development (2001) 1.56
Prevalence of speech and language disorders in 5-year-old kindergarten children in the Ottawa-Carleton region. J Speech Hear Disord (1986) 1.56
MKP5, a new member of the MAP kinase phosphatase family, which selectively dephosphorylates stress-activated kinases. Oncogene (1999) 1.55
Evaluation of impotence in older men. West J Med (1985) 1.54