Published in Am J Med Genet on February 15, 2002
118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects. BMC Med Genet (2009) 1.74
Genetic variation in the one-carbon transfer pathway and ovarian cancer risk. Cancer Res (2008) 1.42
Insights into metabolic mechanisms underlying folate-responsive neural tube defects: a minireview. Birth Defects Res A Clin Mol Teratol (2009) 1.29
Pharmacogenetic and metabolite measurements are associated with clinical status in patients with rheumatoid arthritis treated with methotrexate: results of a multicentred cross sectional observational study. Ann Rheum Dis (2005) 1.26
Variation in folate pathway genes contributes to risk of congenital heart defects among individuals with Down syndrome. Genet Epidemiol (2010) 1.14
Gene-environment interactions, folate metabolism and the embryonic nervous system. Wiley Interdiscip Rev Syst Biol Med (2010) 1.14
Association of genetic polymorphism in the folate metabolic pathway with methotrexate pharmacokinetics and toxicity in childhood acute lymphoblastic leukaemia and malignant lymphoma. Eur J Clin Pharmacol (2011) 1.10
Genetic determinants of methotrexate toxicity in rheumatoid arthritis patients: a study of polymorphisms affecting methotrexate transport and folate metabolism. Eur J Clin Pharmacol (2008) 1.03
Neural tube defects, folic acid and methylation. Int J Environ Res Public Health (2013) 0.95
Maternal and infant gene-folate interactions and the risk of neural tube defects. Am J Med Genet A (2012) 0.95
The reduced folate carrier (SLC19A1) c.80G>A polymorphism is associated with red cell folate concentrations among women. Ann Hum Genet (2009) 0.94
Current perspectives on the genetic causes of neural tube defects. Neurogenetics (2006) 0.92
Folic acid and human reproduction-ten important issues for clinicians. J Exp Clin Assist Reprod (2011) 0.90
Methylenetetrahydrofolate reductase (MTHFR) and susceptibility for (pre)neoplastic cervical disease. Hum Genet (2005) 0.88
Cleft lip and palate genetics and application in early embryological development. Indian J Plast Surg (2009) 0.88
Reduced folate carrier 80A-->G polymorphism, plasma folate, and risk of placental abruption. Hum Genet (2008) 0.88
Knockout of the folate transporter folt-1 causes germline and somatic defects in C. elegans. BMC Dev Biol (2010) 0.87
Influence of Methylenetetrahydrofolate Reductase C677T, A1298C, and G80A Polymorphisms on the Survival of Pediatric Patients with Acute Lymphoblastic Leukemia. Leuk Res Treatment (2012) 0.84
Identifying women who might benefit from higher doses of folic acid in pregnancy. Can Fam Physician (2012) 0.84
Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex. BMC Genomics (2008) 0.83
Nonsyndromic cleft lip and palate: CRISPLD genes and the folate gene pathway connection. Birth Defects Res A Clin Mol Teratol (2010) 0.79
SLC19A1 pharmacogenomics summary. Pharmacogenet Genomics (2010) 0.78
RFC-1 80G>A polymorphism in case-mother/control-mother dyads is associated with risk of nephroblastoma and neuroblastoma. Genet Test Mol Biomarkers (2014) 0.77
Methylenetetrahydrofolate reductase C677T polymorphism and susceptibility to cervical cancer and cervical intraepithelial neoplasia: a meta-analysis. PLoS One (2012) 0.76
The A1298C Methylenetetrahydrofolate Reductase Gene Variant as a Susceptibility Gene for Non-Syndromic Conotruncal Heart Defects in an Indian Population. Pediatr Cardiol (2015) 0.76
Folic acid supplementation for pregnant women and those planning pregnancy: 2015 update. J Clin Pharmacol (2015) 0.75
Replication and exploratory analysis of 24 candidate risk polymorphisms for neural tube defects. BMC Med Genet (2014) 0.75
Mutations in folate transporter genes and risk for human myelomeningocele. Am J Med Genet A (2017) 0.75
Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes. Nat Genet (2002) 6.29
The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm Genome (2012) 2.65
Decrease in depression symptoms is associated with longer survival in patients with metastatic breast cancer: a secondary analysis. J Clin Oncol (2010) 2.33
Neural tube defects and folate: case far from closed. Nat Rev Neurosci (2006) 2.30
A new partner for the international knockout mouse consortium. Cell (2007) 2.23
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res (2008) 2.08
Maternal periconceptional vitamins: interactions with selected factors and congenital anomalies? Epidemiology (2002) 1.93
The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development. Nat Cell Biol (2009) 1.90
The continuing challenge of understanding, preventing, and treating neural tube defects. Science (2013) 1.86
Variation in IRF6 contributes to nonsyndromic cleft lip and palate. Am J Med Genet A (2005) 1.82
118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects. BMC Med Genet (2009) 1.74
Maternal smoking and environmental tobacco smoke exposure and the risk of orofacial clefts. Epidemiology (2007) 1.67
Maternal smoking and the risk of orofacial clefts: Susceptibility with NAT1 and NAT2 polymorphisms. Epidemiology (2004) 1.63
A mouse model of hereditary folate malabsorption: deletion of the PCFT gene leads to systemic folate deficiency. Blood (2011) 1.62
NAT2 variation and idiopathic talipes equinovarus (clubfoot). Am J Med Genet A (2007) 1.57
Orofacial clefts in the National Birth Defects Prevention Study, 1997-2004. Am J Med Genet A (2009) 1.55
Schizencephaly: heterogeneous etiologies in a population of 4 million California births. Am J Med Genet A (2005) 1.55
FOXE1 association with both isolated cleft lip with or without cleft palate, and isolated cleft palate. Hum Mol Genet (2009) 1.55
Mid-pregnancy cotinine and risks of orofacial clefts and neural tube defects. J Pediatr (2008) 1.52
Design decisions to optimize reliability of daytime cortisol slopes in an older population. Am J Geriatr Psychiatry (2006) 1.49
Prevalence of CGG expansions of the FMR1 gene in a US population-based sample. Am J Med Genet B Neuropsychiatr Genet (2012) 1.49
Identification of novel candidate gene loci and increased sex chromosome aneuploidy among infants with conotruncal heart defects. Am J Med Genet A (2013) 1.48
Diacylglycerol kinase K variants impact hypospadias in a California study population. J Urol (2012) 1.43
Mutations in KAT6B, encoding a histone acetyltransferase, cause Genitopatellar syndrome. Am J Hum Genet (2012) 1.39
Association of selected persistent organic pollutants in the placenta with the risk of neural tube defects. Proc Natl Acad Sci U S A (2011) 1.38
Novel mutations in VANGL1 in neural tube defects. Hum Mutat (2009) 1.37
Multiplexed genetic analysis using an expanded genetic alphabet. Clin Chem (2004) 1.37
Stress-induced redistribution of immune cells--from barracks to boulevards to battlefields: a tale of three hormones--Curt Richter Award winner. Psychoneuroendocrinology (2012) 1.34
Maternal corticosteroid use and orofacial clefts. Am J Obstet Gynecol (2007) 1.34
Homocysteine remethylation enzyme polymorphisms and increased risks for neural tube defects. Mol Genet Metab (2003) 1.25
Selected gene polymorphisms and their interaction with maternal smoking, as risk factors for gastroschisis. Birth Defects Res A Clin Mol Teratol (2006) 1.25
Patterns of infantile hemangiomas: new clues to hemangioma pathogenesis and embryonic facial development. Pediatrics (2006) 1.24
Depression and stress reactivity in metastatic breast cancer. Psychosom Med (2006) 1.22
Comprehensive EMX2 genotyping of a large schizencephaly case series. Am J Med Genet A (2007) 1.22
Integration of DNA sample collection into a multi-site birth defects case-control study. Teratology (2002) 1.22
Association between a leukotriene C4 synthase gene promoter polymorphism and coronary artery calcium in young women: the Muscatine Study. Arterioscler Thromb Vasc Biol (2006) 1.19
Risks of human conotruncal heart defects associated with 32 single nucleotide polymorphisms of selected cardiovascular disease-related genes. Am J Med Genet A (2005) 1.18
Choline and risk of neural tube defects in a folate-fortified population. Epidemiology (2009) 1.18
Environmental and genetic contributors to hypospadias: a review of the epidemiologic evidence. Birth Defects Res A Clin Mol Teratol (2012) 1.17
Folic acid in early pregnancy: a public health success story. FASEB J (2010) 1.16
Maternal occupational exposure to polycyclic aromatic hydrocarbons: effects on gastroschisis among offspring in the National Birth Defects Prevention Study. Environ Health Perspect (2012) 1.16
Maternal periconceptional smoking and alcohol consumption and risk for select congenital anomalies. Birth Defects Res A Clin Mol Teratol (2008) 1.15
Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation. J Clin Invest (2010) 1.14
Cancer supportive care, improving the quality of life for cancer patients. A program evaluation report. Support Care Cancer (2004) 1.13
Maternal reproductive and demographic characteristics as risk factors for hypospadias. Paediatr Perinat Epidemiol (2007) 1.13
Periconceptional multivitamin intake during early pregnancy, genetic variation of acetyl-N-transferase 1 (NAT1), and risk for orofacial clefts. Birth Defects Res A Clin Mol Teratol (2004) 1.13
Embryonic development of folate binding protein-1 (Folbp1) knockout mice: Effects of the chemical form, dose, and timing of maternal folate supplementation. Dev Dyn (2004) 1.10
Association between non-suicidal self-injuries and suicide attempts in Chinese adolescents and college students: a cross-section study. PLoS One (2011) 1.10
The Stanford Integrated Psychosocial Assessment for Transplantation: A Prospective Study of Medical and Psychosocial Outcomes. Psychosom Med (2015) 1.09
Reduced folate carrier polymorphism (80A-->G) and neural tube defects. Eur J Hum Genet (2003) 1.08
Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice. FASEB J (2009) 1.07
Folate pathway and nonsyndromic cleft lip and palate. Birth Defects Res A Clin Mol Teratol (2010) 1.06
Spontaneous neural tube defects in splotch mice supplemented with selected micronutrients. Toxicol Appl Pharmacol (2005) 1.06
Maternal stressful life events and risks of birth defects. Epidemiology (2007) 1.06
Study of MTHFR and MS polymorphisms as risk factors for NTD in the Italian population. J Hum Genet (2002) 1.06
Investigations into the etiology of neural tube defects. Birth Defects Res C Embryo Today (2004) 1.05
Teratogenic effects of antiepileptic drugs. Expert Rev Neurother (2010) 1.05
Whole genome microarray analysis, from neonatal blood cards. BMC Genet (2009) 1.05
Are the betaine-homocysteine methyltransferase (BHMT and BHMT2) genes risk factors for spina bifida and orofacial clefts? Am J Med Genet A (2005) 1.04
HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis. Gastroenterology (2010) 1.04
Endothelial nitric oxide synthase (NOS3) genetic variants, maternal smoking, vitamin use, and risk of human orofacial clefts. Am J Epidemiol (2005) 1.04
Maternal progestin intake and risk of hypospadias. Arch Pediatr Adolesc Med (2005) 1.04
Epidemiologic characteristics of anophthalmia and bilateral microphthalmia among 2.5 million births in California, 1989-1997. Am J Med Genet A (2005) 1.04
Autoantibodies to folate receptor during pregnancy and neural tube defect risk. J Reprod Immunol (2008) 1.03
Fuz controls the morphogenesis and differentiation of hair follicles through the formation of primary cilia. J Invest Dermatol (2010) 1.01
Ovotestes and XY sex reversal in a female with an interstitial 9q33.3-q34.1 deletion encompassing NR5A1 and LMX1B causing features of Genitopatellar syndrome. Am J Med Genet A (2007) 1.01
Maternal occupational exposure to polycyclic aromatic hydrocarbons and risk of neural tube defect-affected pregnancies. Birth Defects Res A Clin Mol Teratol (2012) 1.00
Fetal constraint as a potential risk factor for craniosynostosis. Am J Med Genet A (2010) 1.00
Biomarkers of exposure to combustion by-products in a human population in Shanxi, China. J Expo Sci Environ Epidemiol (2009) 1.00
Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis. Cancer Res (2005) 1.00
Psychophysiological and cortisol responses to psychological stress in depressed and nondepressed older men and women with elevated cardiovascular disease risk. Psychosom Med (2006) 1.00
Neural and orofacial defects in Folp1 knockout mice [corrected]. Birth Defects Res A Clin Mol Teratol (2003) 1.00
Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF-related syndromes. Dev Cell (2013) 0.99
Genetic variation of infant reduced folate carrier (A80G) and risk of orofacial defects and congenital heart defects in China. Ann Epidemiol (2005) 0.99
Associations between polymorphisms within the thymidylate synthase gene and spina bifida. Birth Defects Res A Clin Mol Teratol (2003) 0.99
Maternal smoking, genetic variation of glutathione s-transferases, and risk for orofacial clefts. Epidemiology (2005) 0.98
Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice. Toxicol Lett (2003) 0.98
Genetic variation of infant reduced folate carrier (A80G) and risk of orofacial and conotruncal heart defects. Am J Epidemiol (2003) 0.98
Mutations in planar cell polarity gene SCRIB are associated with spina bifida. PLoS One (2013) 0.98