PubRank

Richard H Finnell

Author PubWeight™ 144.90‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm Genome 2012 2.65
2 Neural tube defects and folate: case far from closed. Nat Rev Neurosci 2006 2.30
3 A new partner for the international knockout mouse consortium. Cell 2007 2.23
4 Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res 2008 2.08
5 Maternal periconceptional vitamins: interactions with selected factors and congenital anomalies? Epidemiology 2002 1.93
6 The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development. Nat Cell Biol 2009 1.90
7 The continuing challenge of understanding, preventing, and treating neural tube defects. Science 2013 1.86
8 Variation in IRF6 contributes to nonsyndromic cleft lip and palate. Am J Med Genet A 2005 1.82
9 118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects. BMC Med Genet 2009 1.74
10 Maternal smoking and the risk of orofacial clefts: Susceptibility with NAT1 and NAT2 polymorphisms. Epidemiology 2004 1.63
11 A mouse model of hereditary folate malabsorption: deletion of the PCFT gene leads to systemic folate deficiency. Blood 2011 1.62
12 Mid-pregnancy cotinine and risks of orofacial clefts and neural tube defects. J Pediatr 2008 1.52
13 Association of selected persistent organic pollutants in the placenta with the risk of neural tube defects. Proc Natl Acad Sci U S A 2011 1.38
14 Novel mutations in VANGL1 in neural tube defects. Hum Mutat 2009 1.37
15 Homocysteine remethylation enzyme polymorphisms and increased risks for neural tube defects. Mol Genet Metab 2003 1.25
16 Integration of DNA sample collection into a multi-site birth defects case-control study. Teratology 2002 1.22
17 Risks of human conotruncal heart defects associated with 32 single nucleotide polymorphisms of selected cardiovascular disease-related genes. Am J Med Genet A 2005 1.18
18 Choline and risk of neural tube defects in a folate-fortified population. Epidemiology 2009 1.18
19 Maternal periconceptional vitamin use, genetic variation of infant reduced folate carrier (A80G), and risk of spina bifida. Am J Med Genet 2002 1.17
20 Folic acid in early pregnancy: a public health success story. FASEB J 2010 1.16
21 Maternal occupational exposure to polycyclic aromatic hydrocarbons: effects on gastroschisis among offspring in the National Birth Defects Prevention Study. Environ Health Perspect 2012 1.16
22 Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation. J Clin Invest 2010 1.14
23 Periconceptional multivitamin intake during early pregnancy, genetic variation of acetyl-N-transferase 1 (NAT1), and risk for orofacial clefts. Birth Defects Res A Clin Mol Teratol 2004 1.13
24 Embryonic development of folate binding protein-1 (Folbp1) knockout mice: Effects of the chemical form, dose, and timing of maternal folate supplementation. Dev Dyn 2004 1.10
25 Reduced folate carrier polymorphism (80A-->G) and neural tube defects. Eur J Hum Genet 2003 1.08
26 Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice. FASEB J 2009 1.07
27 Folate pathway and nonsyndromic cleft lip and palate. Birth Defects Res A Clin Mol Teratol 2010 1.06
28 Spontaneous neural tube defects in splotch mice supplemented with selected micronutrients. Toxicol Appl Pharmacol 2005 1.06
29 Study of MTHFR and MS polymorphisms as risk factors for NTD in the Italian population. J Hum Genet 2002 1.06
30 Investigations into the etiology of neural tube defects. Birth Defects Res C Embryo Today 2004 1.05
31 Teratogenic effects of antiepileptic drugs. Expert Rev Neurother 2010 1.05
32 Whole genome microarray analysis, from neonatal blood cards. BMC Genet 2009 1.05
33 Are the betaine-homocysteine methyltransferase (BHMT and BHMT2) genes risk factors for spina bifida and orofacial clefts? Am J Med Genet A 2005 1.04
34 HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis. Gastroenterology 2010 1.04
35 Endothelial nitric oxide synthase (NOS3) genetic variants, maternal smoking, vitamin use, and risk of human orofacial clefts. Am J Epidemiol 2005 1.04
36 Epidemiologic characteristics of anophthalmia and bilateral microphthalmia among 2.5 million births in California, 1989-1997. Am J Med Genet A 2005 1.04
37 Autoantibodies to folate receptor during pregnancy and neural tube defect risk. J Reprod Immunol 2008 1.03
38 Fuz controls the morphogenesis and differentiation of hair follicles through the formation of primary cilia. J Invest Dermatol 2010 1.01
39 Neural and orofacial defects in Folp1 knockout mice [corrected]. Birth Defects Res A Clin Mol Teratol 2003 1.00
40 Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis. Cancer Res 2005 1.00
41 Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF-related syndromes. Dev Cell 2013 0.99
42 Genetic variation of infant reduced folate carrier (A80G) and risk of orofacial defects and congenital heart defects in China. Ann Epidemiol 2005 0.99
43 Associations between polymorphisms within the thymidylate synthase gene and spina bifida. Birth Defects Res A Clin Mol Teratol 2003 0.99
44 Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice. Toxicol Lett 2003 0.98
45 Maternal smoking, genetic variation of glutathione s-transferases, and risk for orofacial clefts. Epidemiology 2005 0.98
46 Genetic variation of infant reduced folate carrier (A80G) and risk of orofacial and conotruncal heart defects. Am J Epidemiol 2003 0.98
47 Mutations in planar cell polarity gene SCRIB are associated with spina bifida. PLoS One 2013 0.98
48 Embryonic development in the reduced folate carrier knockout mouse is modulated by maternal folate supplementation. Birth Defects Res A Clin Mol Teratol 2008 0.98
49 Defective sumoylation pathway directs congenital heart disease. Birth Defects Res A Clin Mol Teratol 2011 0.97
50 Reproductive consequences of oral arsenate exposure during pregnancy in a mouse model. Birth Defects Res B Dev Reprod Toxicol 2008 0.97
51 Renal tubular reabsorption of folate mediated by folate binding protein 1. J Am Soc Nephrol 2005 0.96
52 Maternal and infant gene-folate interactions and the risk of neural tube defects. Am J Med Genet A 2012 0.95
53 Excess S-adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis. Hepatology 2013 0.94
54 Differentially expressed genes in embryonic cardiac tissues of mice lacking Folr1 gene activity. BMC Dev Biol 2007 0.94
55 Importance of folate-homocysteine homeostasis during early embryonic development. Clin Chem Lab Med 2007 0.93
56 Fetal and maternal MTHFR C677T genotype, maternal folate intake and the risk of nonsyndromic oral clefts. Am J Med Genet A 2007 0.93
57 Maternal occupational chemical exposures and biotransformation genotypes as risk factors for selected congenital anomalies. Am J Epidemiol 2003 0.93
58 Antiepileptic drugs and pregnancy outcomes. Am J Med Genet A 2012 0.92
59 Developmental consequences of abnormal folate transport during murine heart morphogenesis. Birth Defects Res A Clin Mol Teratol 2004 0.91
60 Mouse Fkbp8 activity is required to inhibit cell death and establish dorso-ventral patterning in the posterior neural tube. Hum Mol Genet 2007 0.91
61 Diabetes and obesity-related genes and the risk of neural tube defects in the national birth defects prevention study. Am J Epidemiol 2012 0.90
62 Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid. J Med Chem 2009 0.90
63 Fuz regulates craniofacial development through tissue specific responses to signaling factors. PLoS One 2011 0.90
64 Genetic basis of susceptibility to teratogen induced birth defects. Am J Med Genet C Semin Med Genet 2011 0.89
65 Arsenate-induced maternal glucose intolerance and neural tube defects in a mouse model. Toxicol Appl Pharmacol 2009 0.89
66 Screening for novel PAX3 polymorphisms and risks of spina bifida. Birth Defects Res A Clin Mol Teratol 2007 0.88
67 Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies. Toxicol Appl Pharmacol 2005 0.88
68 Autoantibodies to folate receptor alpha during early pregnancy and risk of oral clefts in Denmark. Pediatr Res 2010 0.88
69 Phosphatidylethanolamine N-methyltransferase (PEMT) gene polymorphisms and risk of spina bifida. Am J Med Genet A 2006 0.87
70 Cardiovascular abnormalities in Folr1 knockout mice and folate rescue. Birth Defects Res A Clin Mol Teratol 2007 0.87
71 Promoter haplotype combinations for the human PDGFRA gene are associated with risk of neural tube defects. Mol Genet Metab 2004 0.87
72 Stereoselective anticonvulsant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential. Epilepsia 2013 0.86
73 Transcriptional regulation of the novel Toll-like receptor Tlr13. J Biol Chem 2009 0.86
74 Effects of dietary folate intake and folate binding protein-2 (Folbp2) on urinary speciation of sodium arsenate in mice. Environ Toxicol Pharmacol 2005 0.86
75 Variable contribution of the MTHFR C677T polymorphism to non-syndromic cleft lip and palate risk in China. Am J Med Genet A 2006 0.85
76 Valproic acid-induced skeletal malformations: associated gene expression cascades. Pharmacogenet Genomics 2005 0.85
77 CHKA and PCYT1A gene polymorphisms, choline intake and spina bifida risk in a California population. BMC Med 2006 0.85
78 Effects of folate supplementation on the risk of spontaneous and induced neural tube defects in Splotch mice. Teratology 2002 0.85
79 Folate-regulated changes in gene expression in the anterior neural tube of folate binding protein-1 (Folbp1)-deficient murine embryos. Neurochem Res 2004 0.84
80 A cannabinoid analogue of Delta9-tetrahydrocannabinol disrupts neural development in chick. Birth Defects Res B Dev Reprod Toxicol 2008 0.84
81 Elevated complement factor C5a in maternal and umbilical cord plasma in preeclampsia. J Reprod Immunol 2013 0.84
82 Valproate-induced neural tube defects in folate-binding protein-2 (Folbp2) knockout mice. Birth Defects Res A Clin Mol Teratol 2003 0.84
83 Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in Apcmin/+ mice. J Nutr Biochem 2006 0.84
84 Evaluation of the antiallodynic, teratogenic and pharmacokinetic profile of stereoisomers of valnoctamide, an amide derivative of a chiral isomer of valproic acid. Neuropharmacology 2010 0.84
85 Arsenic-induced gene expression changes in the neural tube of folate transport defective mouse embryos. Neurotoxicology 2006 0.84
86 Planar cell polarity pathway genes and risk for spina bifida. Am J Med Genet A 2010 0.83
87 Rare LRP6 variants identified in spina bifida patients. Hum Mutat 2015 0.83
88 Risks of human limb deficiency anomalies associated with 29 SNPs of genes involved in homocysteine metabolism, coagulation, cell-cell interactions, inflammatory response, and blood pressure regulation. Am J Med Genet A 2006 0.83
89 Initial characterization of mice null for Lphn3, a gene implicated in ADHD and addiction. Brain Res 2012 0.83
90 Epigenetic alterations in folate transport genes in placental tissue from fetuses with neural tube defects and in leukocytes from subjects with hyperhomocysteinemia. Epigenetics 2013 0.83
91 Anticonvulsant profile and teratogenicity of N-methyl-tetramethylcyclopropyl carboxamide: a new antiepileptic drug. Epilepsia 2002 0.83
92 Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex. BMC Genomics 2008 0.83
93 Risk factors for neural tube defects: associations between uncoupling protein 2 polymorphisms and spina bifida. Birth Defects Res A Clin Mol Teratol 2003 0.83
94 Maternal smoking during early pregnancy, GSTP1 and EPHX1 variants, and risk of isolated orofacial clefts. Cleft Palate Craniofac J 2007 0.83
95 A known functional polymorphism (Ile120Val) of the human PCMT1 gene and risk of spina bifida. Mol Genet Metab 2005 0.82
96 Evaluation of the Cited2 gene and risk for spina bifida and congenital heart defects. Am J Med Genet A 2004 0.82
97 Folate modulates Hox gene-controlled skeletal phenotypes. Genesis 2004 0.82
98 Role of Folbp1 in the regional regulation of apoptosis and cell proliferation in the developing neural tube and craniofacies. Am J Med Genet C Semin Med Genet 2005 0.82
99 C5a receptor signaling prevents folate deficiency-induced neural tube defects in mice. J Immunol 2013 0.82
100 Gene variants in the folate-mediated one-carbon metabolism (FOCM) pathway as risk factors for conotruncal heart defects. Am J Med Genet A 2012 0.81
101 Retinoic acid-dependent signaling pathways and lineage events in the developing mouse spinal cord. PLoS One 2012 0.81
102 Regulation of folate receptor 1 gene expression in the visceral endoderm. Birth Defects Res A Clin Mol Teratol 2009 0.81
103 Reduced folate carrier gene is a risk factor for neural tube defects in a Chinese population. Birth Defects Res A Clin Mol Teratol 2005 0.81
104 Nested case-control study of one-carbon metabolites in mid-pregnancy and risks of cleft lip with and without cleft palate. Pediatr Res 2009 0.81
105 Genetic dissection of hyperthermia-induced neural tube defects in mice. Birth Defects Res A Clin Mol Teratol 2003 0.81
106 Evaluation of the jumonji gene and risk for spina bifida and congenital heart defects. Am J Med Genet A 2004 0.81
107 Association between CFL1 gene polymorphisms and spina bifida risk in a California population. BMC Med Genet 2007 0.81
108 Cannabinoid receptor 1 signaling in embryo neurodevelopment. Birth Defects Res B Dev Reprod Toxicol 2012 0.80
109 Developmental outcome of levetiracetam, its major metabolite in humans, 2-pyrrolidinone N-butyric acid, and its enantiomer (R)-alpha-ethyl-oxo-pyrrolidine acetamide in a mouse model of teratogenicity. Epilepsia 2003 0.80
110 Evaluation of infant methylenetetrahydrofolate reductase genotype, maternal vitamin use, and risk of high versus low level spina bifida defects. Birth Defects Res A Clin Mol Teratol 2003 0.80
111 Limb deficiency defects, MSX1, and exposure to tobacco smoke. Am J Med Genet A 2004 0.79
112 Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid. J Med Chem 2007 0.79
113 Stereoselective pharmacodynamic and pharmacokinetic analysis of sec-Butylpropylacetamide (SPD), a new CNS-active derivative of valproic acid with unique activity against status epilepticus. J Med Chem 2013 0.79
114 Gene-specific monitoring of T7-based RNA amplification by real-time quantitative PCR. Biotechniques 2003 0.79
115 Untargeted metabolite profiling of murine embryos to reveal metabolic perturbations associated with neural tube closure defects. Birth Defects Res A Clin Mol Teratol 2014 0.79
116 Functional regulation of P-glycoprotein at the blood-brain barrier in proton-coupled folate transporter (PCFT) mutant mice. FASEB J 2012 0.79
117 Genes encoding critical transcriptional activators for murine neural tube development and human spina bifida: a case-control study. BMC Med Genet 2010 0.79
118 Genetic polymorphisms in the thioredoxin 2 (TXN2) gene and risk for spina bifida. Am J Med Genet A 2009 0.78
119 Genes encoding catalytic subunits of protein kinase A and risk of spina bifida. Birth Defects Res A Clin Mol Teratol 2005 0.78
120 A GCH1 haplotype and risk of neural tube defects in the National Birth Defects Prevention Study. Mol Genet Metab 2012 0.78
121 Comparative pharmacodynamic and pharmacokinetic analysis of two anticonvulsant halo derivatives of 2,2,3,3-tetramethylcyclopropanecarboxamide, an amide of a cyclic analog of valproic acid. Epilepsia 2010 0.78
122 Characterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents. Br J Pharmacol 2003 0.78
123 Anticonvulsant activity, teratogenicity and pharmacokinetics of novel valproyltaurinamide derivatives in mice. Br J Pharmacol 2003 0.78
124 Arsenic urinary speciation in Mthfr deficient mice injected with sodium arsenate. Toxicol Lett 2012 0.78
125 Gas chromatographic determination of novel valproyl taurinamide derivatives in mouse and dog plasma. J Chromatogr B Analyt Technol Biomed Life Sci 2003 0.77
126 Another key role for the cardiac neural crest in heart development. Am J Physiol Heart Circ Physiol 2006 0.77
127 Syntheses and evaluation of anticonvulsant profile and teratogenicity of novel amide derivatives of branched aliphatic carboxylic acids with 4-aminobenzensulfonamide. J Med Chem 2010 0.77
128 Levels of polycyclic aromatic hydrocarbons in maternal serum and risk of neural tube defects in offspring. Environ Sci Technol 2014 0.77
129 Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative. Epilepsia 2009 0.77
130 Mapping a chromosomal locus for valproic acid-induced exencephaly in mice. Mamm Genome 2004 0.77
131 Levels of PAH-DNA adducts in placental tissue and the risk of fetal neural tube defects in a Chinese population. Reprod Toxicol 2013 0.77
132 Teratogenicity of valproate conjugates with anticonvulsant activity in mice. Epilepsy Res 2003 0.77
133 Use of a novel genetic mouse model to investigate the role of folate in colitis-associated colon cancer. J Nutr Biochem 2008 0.77
134 High-affinity folate receptor in cardiac neural crest migration: a gene knockdown model using siRNA. Dev Dyn 2010 0.77
135 Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS-active carbamate derivatives of valproic acid. Epilepsia 2014 0.77
136 Nicotinamide N-methyl transferase (NNMT) gene polymorphisms and risk for spina bifida. Birth Defects Res A Clin Mol Teratol 2008 0.76
137 Apolipoprotein E and apolipoprotein B genotypes and risk for spina bifida. Teratology 2002 0.76
138 Brief report novel mechanism for valproate-induced teratogenicity. Birth Defects Res A Clin Mol Teratol 2014 0.76
139 The transcobalamin receptor knockout mouse: a model for vitamin B12 deficiency in the central nervous system. FASEB J 2013 0.76
140 Does global hypomethylation contribute to susceptibility to neural tube defects? Am J Clin Nutr 2010 0.76
141 Thymidylate synthase polymorphisms and risk of conotruncal heart defects. Am J Med Genet A 2012 0.76
142 Preclinical evaluation of 2,2,3,3-tetramethylcyclopropanecarbonyl-urea, a novel, second generation to valproic acid, antiepileptic drug. Neuropharmacology 2006 0.76
143 Lack of association between ZIC2 and ZIC3 genes and the risk of neural tube defects (NTDs) in Hispanic populations. Am J Med Genet A 2003 0.76
144 Exon sequencing of PAX3 and T (brachyury) in cases with spina bifida. Birth Defects Res A Clin Mol Teratol 2013 0.76
145 A critical role of noggin in developing folate-nonresponsive NTD in Fkbp8 -/- embryos. Childs Nerv Syst 2014 0.76
146 Myo-inositol enhances teratogenicity of valproic acid in the mouse. Birth Defects Res A Clin Mol Teratol 2006 0.75
147 Genetic variation in the proto-oncogene SKI and risk for orofacial clefting. Mol Genet Metab 2005 0.75
148 Transcriptional analyses of two mouse models of spina bifida. Birth Defects Res A Clin Mol Teratol 2012 0.75
149 Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid. Epilepsia 2008 0.75
150 Novel folate binding protein-1 interactions in embryonic orofacial tissue. Life Sci 2010 0.75
151 Infant C677T MTHFR polymorphism and severe mental retardation. Birth Defects Res A Clin Mol Teratol 2007 0.75
152 Apolipoprotein B and apolipoprotein E genotypes and sporadic holoprosencephaly. Am J Med Genet 2002 0.75
153 Design and pharmacological activity of glycinamide and N-methoxy amide derivatives of analogs and constitutional isomers of valproic acid. Epilepsy Behav 2011 0.75
154 Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide. Epilepsy Res 2006 0.75
155 Correction to Levels of Polycyclic Aromatic Hydrocarbons in Maternal Serum and Risk of Neural Tube Defects in Offspring. Environ Sci Technol 2015 0.75
156 Is Sonic hedgehog (SHH) a candidate gene for spina bifida? A pilot study. Am J Med Genet A 2003 0.75
157 Nutrient intakes in women and risks of anophthalmia and microphthalmia in their offspring. Birth Defects Res A Clin Mol Teratol 2007 0.75