Published in Development on February 01, 2002
Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11). Proc Natl Acad Sci U S A (2006) 4.16
Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies. J Neural Transm (Vienna) (2008) 2.43
The MACPF/CDC family of pore-forming toxins. Cell Microbiol (2008) 2.15
Guiding neuronal cell migrations. Cold Spring Harb Perspect Biol (2010) 1.82
Molecular genetics of addiction and related heritable phenotypes: genome-wide association approaches identify "connectivity constellation" and drug target genes with pleiotropic effects. Ann N Y Acad Sci (2008) 1.69
Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cell. Mol Endocrinol (2010) 1.47
N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma. Genes Dev (2009) 1.45
Cerebellum development and medulloblastoma. Curr Top Dev Biol (2011) 1.40
Identification of piRNAs in the central nervous system. RNA (2011) 1.39
Astn2, a novel member of the astrotactin gene family, regulates the trafficking of ASTN1 during glial-guided neuronal migration. J Neurosci (2010) 1.35
Deficits in motor coordination with aberrant cerebellar development in mice lacking testicular orphan nuclear receptor 4. Mol Cell Biol (2005) 1.31
The role of Rho GTPase proteins in CNS neuronal migration. Dev Neurobiol (2011) 1.28
Disruption of the ASTN2/TRIM32 locus at 9q33.1 is a risk factor in males for autism spectrum disorders, ADHD and other neurodevelopmental phenotypes. Hum Mol Genet (2013) 1.26
Timing neurogenesis and differentiation: insights from quantitative clonal analyses of cerebellar granule cells. J Neurosci (2008) 1.19
Completion of neuronal migration regulated by loss of Ca(2+) transients. Proc Natl Acad Sci U S A (2004) 1.14
Long noncoding RNA HOTAIR is relevant to cellular proliferation, invasiveness, and clinical relapse in small-cell lung cancer. Cancer Med (2014) 1.08
Neuronal migration and molecular conservation with leukocyte chemotaxis. Genes Dev (2002) 1.02
Huwe1 ubiquitin ligase is essential to synchronize neuronal and glial differentiation in the developing cerebellum. Proc Natl Acad Sci U S A (2010) 1.01
Neuron-derived FGF9 is essential for scaffold formation of Bergmann radial fibers and migration of granule neurons in the cerebellum. Dev Biol (2009) 1.01
Effects of MACPF/CDC proteins on lipid membranes. Cell Mol Life Sci (2012) 1.00
PAPPA2, an enzyme that cleaves an insulin-like growth-factor-binding protein, is a candidate gene for a quantitative trait locus affecting body size in mice. Genetics (2006) 1.00
Vav3-deficient mice exhibit a transient delay in cerebellar development. Mol Biol Cell (2010) 0.96
N-cadherin regulates radial glial fiber-dependent migration of cortical locomoting neurons. Commun Integr Biol (2011) 0.96
Profilin1 is required for glial cell adhesion and radial migration of cerebellar granule neurons. EMBO Rep (2011) 0.95
Sticky situations: recent advances in control of cell adhesion during neuronal migration. Curr Opin Neurobiol (2012) 0.95
Cell biology in neuroscience: mechanisms of cell migration in the nervous system. J Cell Biol (2013) 0.93
Altered cerebellar development in nuclear receptor TAK1/ TR4 null mice is associated with deficits in GLAST(+) glia, alterations in social behavior, motor learning, startle reactivity, and microglia. Cerebellum (2010) 0.91
Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFdelta/delta mouse model of amyotrophic lateral sclerosis. BMC Genomics (2010) 0.91
Cellullar insights into cerebral cortical development: focusing on the locomotion mode of neuronal migration. Front Cell Neurosci (2015) 0.90
Consensus Paper: Cerebellar Development. Cerebellum (2016) 0.89
Impaired motor coordination and disrupted cerebellar architecture in Fgfr1 and Fgfr2 double knockout mice. Brain Res (2012) 0.89
Regulation of cell adhesion and migration in cortical neurons: Not only Rho but also Rab family small GTPases. Small GTPases (2011) 0.84
Role of the actin-binding protein profilin1 in radial migration and glial cell adhesion of granule neurons in the cerebellum. Cell Adh Migr (2012) 0.83
Characterization of biological pathways associated with a 1.37 Mbp genomic region protective of hypertension in Dahl S rats. Physiol Genomics (2014) 0.82
ASTN1 and alcohol dependence: family-based association analysis in multiplex alcohol dependence families. Am J Med Genet B Neuropsychiatr Genet (2012) 0.81
A marked paucity of granule cells in the developing cerebellum of the Npc1(-/-) mouse is corrected by a single injection of hydroxypropyl-β-cyclodextrin. Neurobiol Dis (2014) 0.81
Repurposing a pore: highly conserved perforin-like proteins with alternative mechanisms. Philos Trans R Soc Lond B Biol Sci (2017) 0.80
Identification of Astrotactin2 as a Genetic Modifier That Regulates the Global Orientation of Mammalian Hair Follicles. PLoS Genet (2015) 0.79
Four distinct phases of basket/stellate cell migration after entering their final destination (the molecular layer) in the developing cerebellum. Dev Biol (2009) 0.79
Brinp1 (-/-) mice exhibit autism-like behaviour, altered memory, hyperactivity and increased parvalbumin-positive cortical interneuron density. Mol Autism (2016) 0.78
1q25.2-q31.3 Deletion in a female with mental retardation, clinodactyly, minor facial anomalies but no growth retardation. Mol Cytogenet (2013) 0.77
A rapid screening method for population-specific neuronal motogens, substrates and associated signaling pathways. J Neurosci Methods (2007) 0.77
Pathway-Based Genome-Wide Association Studies for Plasma Triglycerides in Obese Females and Normal-Weight Controls. PLoS One (2015) 0.77
Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development. Open Biol (2016) 0.76
Neuroblast migration and P2Y(1) receptor mediated calcium signalling depend on 9-O-acetyl GD3 ganglioside. ASN Neuro (2012) 0.75
piRNAs and Their Functions in the Brain. Int J Hum Genet (2016) 0.75
Replicated Risk Nicotinic Cholinergic Receptor Genes for Nicotine Dependence. Genes (Basel) (2016) 0.75
Development of the Cellular Immune System of Drosophila Requires the Membrane Attack Complex/Perforin-Like Protein Torso-Like. Genetics (2016) 0.75
Effects of Transforming Growth Factor Beta 1 in Cerebellar Development: Role in Synapse Formation. Front Cell Neurosci (2016) 0.75
Intramembrane proteolysis of Astrotactins. J Biol Chem (2017) 0.75
Transcriptome-wide piRNA profiling in human brains of Alzheimer's disease. Neurobiol Aging (2017) 0.75
Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain. Front Cell Neurosci (2017) 0.75
A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature (2003) 16.48
Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs. J Neurosci (2007) 5.87
A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development. Nat Cell Biol (2005) 3.89
Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth. Proc Natl Acad Sci U S A (2002) 3.34
Par6alpha signaling controls glial-guided neuronal migration. Nat Neurosci (2004) 3.06
Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1. Nat Neurosci (2010) 2.90
Role of Unc51.1 and its binding partners in CNS axon outgrowth. Genes Dev (2004) 2.34
The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation. Genes Dev (2005) 2.14
A mutation in the SOS1 gene causes hereditary gingival fibromatosis type 1. Am J Hum Genet (2002) 2.04
Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons. Proc Natl Acad Sci U S A (2007) 1.95
Myosin II motors and F-actin dynamics drive the coordinated movement of the centrosome and soma during CNS glial-guided neuronal migration. Neuron (2009) 1.94
DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1. Hum Mol Genet (2006) 1.58
Neuronal polarity in CNS development. Genes Dev (2006) 1.49
Molecular markers of neuronal progenitors in the embryonic cerebellar anlage. J Neurosci (2006) 1.47
Cerebellum development and medulloblastoma. Curr Top Dev Biol (2011) 1.40
UNC-51/ATG1 kinase regulates axonal transport by mediating motor-cargo assembly. Genes Dev (2008) 1.40
Astn2, a novel member of the astrotactin gene family, regulates the trafficking of ASTN1 during glial-guided neuronal migration. J Neurosci (2010) 1.35
The role of Rho GTPase proteins in CNS neuronal migration. Dev Neurobiol (2011) 1.28
Differentiation of ES cells into cerebellar neurons. Proc Natl Acad Sci U S A (2007) 1.27
Unc-51 controls active zone density and protein composition by downregulating ERK signaling. J Neurosci (2009) 1.19
Role of polymorphic variants as genetic modulators of infection in neonatal sepsis. Pediatr Res (2010) 1.19
Expression and mutation analyses implicate ARHGAP29 as the etiologic gene for the cleft lip with or without cleft palate locus identified by genome-wide association on chromosome 1p22. Birth Defects Res A Clin Mol Teratol (2012) 1.16
Growth and micronutrient disturbances in stable, HIV-infected children in Cape Town. Ann Trop Paediatr (2002) 1.01
Differentiation of the midbrain dopaminergic pathways during mouse development. J Comp Neurol (2004) 0.99
mPar6 alpha controls neuronal migration. J Neurosci (2006) 0.94
Genetic loci for pathological myopia are not associated with juvenile myopia. Am J Med Genet (2002) 0.93
PCSK9 reduces the protein levels of the LDL receptor in mouse brain during development and after ischemic stroke. J Lipid Res (2011) 0.93
Gene expression profiling of preplate neurons destined for the subplate: genes involved in transcription, axon extension, neurotransmitter regulation, steroid hormone signaling, and neuronal survival. Cereb Cortex (2009) 0.92
Unc-51/ATG1 controls axonal and dendritic development via kinesin-mediated vesicle transport in the Drosophila brain. PLoS One (2011) 0.92
Mistargeting hippocampal axons by expression of a truncated Eph receptor. Proc Natl Acad Sci U S A (2002) 0.89
DISC1 regulates synaptic vesicle transport via a lithium-sensitive pathway. Neurosci Res (2011) 0.86
WNT3 inhibits cerebellar granule neuron progenitor proliferation and medulloblastoma formation via MAPK activation. PLoS One (2013) 0.86
Radiographic and anatomic characterization of the nasal septal swell body. Arch Otolaryngol Head Neck Surg (2010) 0.86
Lrp12/Mig13a reveals changing patterns of preplate neuronal polarity during corticogenesis that are absent in reeler mutant mice. Cereb Cortex (2010) 0.85
Effects of enamel matrix genes on dental caries are moderated by fluoride exposures. Hum Genet (2014) 0.81
Primary immunodeficiencies: a 27-year review at a tertiary paediatric hospital in Cape Town, South Africa. J Clin Immunol (2010) 0.78
Going to the gemba: identifying opportunities for improvement in radiology. J Am Coll Radiol (2013) 0.75
Markers of susceptibility to acute rheumatic fever: the B-cell antigen D8/17 is not robust as a marker in South Africa. Cardiol Young (2011) 0.75